Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	126205
Gene name Gene Name - the full gene name approved by the HGNC.	NLR family pyrin domain containing 8
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	NLRP8
Synonyms (NCBI Gene) Gene synonyms aliases	CLR19.2, NALP8, NOD16, PAN4
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19q13.43
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the nucleotide-binding oligomerization domain/ leucine rich repeat/ pyrin domain containing (NLRP) subfamily, which belongs to the Nod-like receptor family of proteins. NLRP genes play roles in the mammalian innate immune sys

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miRTarBase ID	miRNA	Experiments	Reference
MIRT540661	hsa-miR-8485	HITS-CLIP	23824327
MIRT540660	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT540659	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT540658	hsa-miR-603	HITS-CLIP	23824327
MIRT540657	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT540656	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT540654	hsa-miR-3941	HITS-CLIP	23824327
MIRT540655	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT540653	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT540652	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT540661	hsa-miR-8485	PAR-CLIP	21572407
MIRT540660	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT540659	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT540658	hsa-miR-603	PAR-CLIP	21572407
MIRT540657	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT540656	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT540654	hsa-miR-3941	PAR-CLIP	21572407
MIRT540655	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT540653	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT540652	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT540661	hsa-miR-8485	HITS-CLIP	23824327
MIRT540660	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT540659	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT540658	hsa-miR-603	HITS-CLIP	23824327
MIRT540657	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT540656	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT540654	hsa-miR-3941	HITS-CLIP	23824327
MIRT540655	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT540653	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT540652	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT540661	hsa-miR-8485	PAR-CLIP	21572407
MIRT540660	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT540659	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT540658	hsa-miR-603	PAR-CLIP	21572407
MIRT540657	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT540656	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT540654	hsa-miR-3941	PAR-CLIP	21572407
MIRT540655	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT540653	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT540652	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT1187290	hsa-miR-122	CLIP-seq
MIRT1187291	hsa-miR-130a	CLIP-seq
MIRT1187292	hsa-miR-130b	CLIP-seq
MIRT1187293	hsa-miR-301a	CLIP-seq
MIRT1187294	hsa-miR-301b	CLIP-seq
MIRT1187295	hsa-miR-3135b	CLIP-seq
MIRT1187296	hsa-miR-3160-3p	CLIP-seq
MIRT1187297	hsa-miR-3194-3p	CLIP-seq
MIRT1187298	hsa-miR-3652	CLIP-seq
MIRT1187299	hsa-miR-3666	CLIP-seq
MIRT1187300	hsa-miR-3672	CLIP-seq
MIRT1187301	hsa-miR-4251	CLIP-seq
MIRT1187302	hsa-miR-4295	CLIP-seq
MIRT1187303	hsa-miR-431	CLIP-seq
MIRT1187304	hsa-miR-4430	CLIP-seq
MIRT1187305	hsa-miR-451b	CLIP-seq
MIRT1187306	hsa-miR-454	CLIP-seq
MIRT1187307	hsa-miR-4659a-3p	CLIP-seq
MIRT1187308	hsa-miR-4659b-3p	CLIP-seq
MIRT1187309	hsa-miR-4685-5p	CLIP-seq
MIRT1187310	hsa-miR-4761-3p	CLIP-seq
MIRT1187311	hsa-miR-4778-3p	CLIP-seq
MIRT1187312	hsa-miR-4797-5p	CLIP-seq
MIRT1187313	hsa-miR-483-3p	CLIP-seq
MIRT1187314	hsa-miR-508-5p	CLIP-seq
MIRT1187315	hsa-miR-526b	CLIP-seq
MIRT1187316	hsa-miR-548m	CLIP-seq
MIRT1187317	hsa-miR-580	CLIP-seq
MIRT1187318	hsa-miR-924	CLIP-seq
MIRT2054266	hsa-miR-1976	CLIP-seq
MIRT2054267	hsa-miR-3663-5p	CLIP-seq
MIRT2054268	hsa-miR-4279	CLIP-seq
MIRT2054269	hsa-miR-4527	CLIP-seq
MIRT2054270	hsa-miR-4722-3p	CLIP-seq
MIRT2054271	hsa-miR-4740-3p	CLIP-seq
MIRT2283406	hsa-miR-1207-3p	CLIP-seq
MIRT1187290	hsa-miR-122	CLIP-seq
MIRT1187291	hsa-miR-130a	CLIP-seq
MIRT1187292	hsa-miR-130b	CLIP-seq
MIRT2283407	hsa-miR-1908	CLIP-seq
MIRT2283408	hsa-miR-197	CLIP-seq
MIRT2054266	hsa-miR-1976	CLIP-seq
MIRT1187293	hsa-miR-301a	CLIP-seq
MIRT1187294	hsa-miR-301b	CLIP-seq
MIRT1187295	hsa-miR-3135b	CLIP-seq
MIRT2283409	hsa-miR-3187-3p	CLIP-seq
MIRT1187297	hsa-miR-3194-3p	CLIP-seq
MIRT1187298	hsa-miR-3652	CLIP-seq
MIRT2054267	hsa-miR-3663-5p	CLIP-seq
MIRT1187299	hsa-miR-3666	CLIP-seq
MIRT2283410	hsa-miR-376c	CLIP-seq
MIRT2283411	hsa-miR-411	CLIP-seq
MIRT2054268	hsa-miR-4279	CLIP-seq
MIRT1187302	hsa-miR-4295	CLIP-seq
MIRT1187303	hsa-miR-431	CLIP-seq
MIRT1187304	hsa-miR-4430	CLIP-seq
MIRT2283412	hsa-miR-4435	CLIP-seq
MIRT2283413	hsa-miR-4438	CLIP-seq
MIRT2054269	hsa-miR-4527	CLIP-seq
MIRT1187306	hsa-miR-454	CLIP-seq
MIRT2283414	hsa-miR-4695-3p	CLIP-seq
MIRT2283415	hsa-miR-4700-3p	CLIP-seq
MIRT2283416	hsa-miR-4701-5p	CLIP-seq
MIRT2283417	hsa-miR-4716-5p	CLIP-seq
MIRT2054270	hsa-miR-4722-3p	CLIP-seq
MIRT2054271	hsa-miR-4740-3p	CLIP-seq
MIRT2283418	hsa-miR-4755-3p	CLIP-seq
MIRT2283419	hsa-miR-4781-3p	CLIP-seq
MIRT1187312	hsa-miR-4797-5p	CLIP-seq
MIRT2283420	hsa-miR-5095	CLIP-seq
MIRT2283421	hsa-miR-5096	CLIP-seq
MIRT2283422	hsa-miR-548s	CLIP-seq
MIRT2283423	hsa-miR-588	CLIP-seq
MIRT2283424	hsa-miR-646	CLIP-seq
MIRT2283425	hsa-miR-663	CLIP-seq
MIRT1187318	hsa-miR-924	CLIP-seq
MIRT1187290	hsa-miR-122	CLIP-seq
MIRT1187291	hsa-miR-130a	CLIP-seq
MIRT1187292	hsa-miR-130b	CLIP-seq
MIRT1187293	hsa-miR-301a	CLIP-seq
MIRT1187294	hsa-miR-301b	CLIP-seq
MIRT1187295	hsa-miR-3135b	CLIP-seq
MIRT1187297	hsa-miR-3194-3p	CLIP-seq
MIRT1187298	hsa-miR-3652	CLIP-seq
MIRT1187299	hsa-miR-3666	CLIP-seq
MIRT1187302	hsa-miR-4295	CLIP-seq
MIRT1187304	hsa-miR-4430	CLIP-seq
MIRT1187306	hsa-miR-454	CLIP-seq
MIRT2283414	hsa-miR-4695-3p	CLIP-seq
MIRT1187290	hsa-miR-122	CLIP-seq
MIRT1187291	hsa-miR-130a	CLIP-seq
MIRT1187292	hsa-miR-130b	CLIP-seq
MIRT1187293	hsa-miR-301a	CLIP-seq
MIRT1187294	hsa-miR-301b	CLIP-seq
MIRT1187295	hsa-miR-3135b	CLIP-seq
MIRT1187297	hsa-miR-3194-3p	CLIP-seq
MIRT1187298	hsa-miR-3652	CLIP-seq
MIRT1187299	hsa-miR-3666	CLIP-seq
MIRT1187302	hsa-miR-4295	CLIP-seq
MIRT1187303	hsa-miR-431	CLIP-seq
MIRT1187304	hsa-miR-4430	CLIP-seq
MIRT1187306	hsa-miR-454	CLIP-seq
MIRT2283414	hsa-miR-4695-3p	CLIP-seq
MIRT1187312	hsa-miR-4797-5p	CLIP-seq
MIRT1187318	hsa-miR-924	CLIP-seq
MIRT1187290	hsa-miR-122	CLIP-seq
MIRT1187291	hsa-miR-130a	CLIP-seq
MIRT1187292	hsa-miR-130b	CLIP-seq
MIRT1187293	hsa-miR-301a	CLIP-seq
MIRT1187294	hsa-miR-301b	CLIP-seq
MIRT1187295	hsa-miR-3135b	CLIP-seq
MIRT1187297	hsa-miR-3194-3p	CLIP-seq
MIRT1187298	hsa-miR-3652	CLIP-seq
MIRT1187299	hsa-miR-3666	CLIP-seq
MIRT1187302	hsa-miR-4295	CLIP-seq
MIRT1187303	hsa-miR-431	CLIP-seq
MIRT1187304	hsa-miR-4430	CLIP-seq
MIRT1187306	hsa-miR-454	CLIP-seq
MIRT2283414	hsa-miR-4695-3p	CLIP-seq
MIRT1187312	hsa-miR-4797-5p	CLIP-seq
MIRT1187318	hsa-miR-924	CLIP-seq

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GO ID	Ontology	Definition	Evidence
GO:0000166	Function	Nucleotide binding	IEA
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0050727	Process	Regulation of inflammatory response	IBA

MIM	HGNC	e!Ensembl
609659	22940	ENSG00000179709

Protein

UniProt ID

Q86W28

Protein name

NACHT, LRR and PYD domains-containing protein 8 (Nucleotide-binding oligomerization domain protein 16) (PYRIN and NACHT-containing protein 4)

Protein function

Involved in inflammation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02758	PYRIN	40 → 115	PAAD/DAPIN/Pyrin domain	Domain
PF05729	NACHT	204 → 373	NACHT domain	Domain
PF17779	NOD2_WH	449 → 505	NOD2 winged helix domain	Domain
PF17776	NLRC4_HD2	508 → 624	NLRC4 helical domain HD2	Domain
PF13516	LRR_6	865 → 887	Leucine Rich repeat	Repeat
PF13516	LRR_6	922 → 945	Leucine Rich repeat	Repeat
PF13516	LRR_6	979 → 1002	Leucine Rich repeat	Repeat

Sequence

MSDVNPPSDTPIPFSSSSTHSSHIPPWTFSCYPGSPCENGVMLYMRNVSHEELQRFKQLL
LTELSTGTMPITWDQVETASWAEVVHLLIERFPGRRAWDVTSNIFAIMNCDKMCVVVRRE
INAILPTLEPEDLNVGETQVNLEEGESGKIRRYKSNVMEKFFPIWDITTWPGNQRDFFYQ
GVHRHEEYLPCLLLPKRPQGRQPKTVAIQGAPGIGKTILAKKVMFEWARNKFYAHKRWCA
FYFHCQEVNQTTDQSFSELIEQKWPGSQDLVSKIMSKPDQLLLLLDGFEELTSTLIDRLE
DLSEDWRQKLPGSVLLSSLLSKTMLPEATLLIMIRFTSWQTCKPLLKCPSLVTLPGFNTM
EKIKYFQMYFGHTEEGDQVLSFAMENTILFSMCRVPVVCWMVCSGLKQQMERGNNLTQSC
PNATSVFVRYISSLFPTRAENFSRKIHQAQLEGLCHLAADSMWHRKWVLGKEDLEEAKLD
QTGVTAFLGMSILRRIAGEEDHYVFTLVTFQEFFAALFYVLCFPQRLKNFHVLSHVNIQR
LIASPRGSKSYLSHMGLFLFGFLNEACASAVEQSFQCKVSFGNKRKLLKVIPLLHKCDPP
SPGSGVPQLFYCLHEIREEAFVSQALNDYHKVVLRIGNNKEVQVSAFCLKRCQYLHEVEL
TVTLNFMNVWKLSSSSHPGSEAPESNGLHRWWQDLCSVFATNDKLEVLTMTNSVLGPPFL
KALAAALRHPQCKLQKLLLRRVNSTMLNQDLIGVLTGNQHLRYLEIQHVEVESKAVKLLC
RVLRSPRCRLQCLRLEDCLATPRIWTDLGNNLQGNGHLKTLILRKNSLENCGAYYLSVAQ
LERLSIENCNLTQLTCESLASCLRQSKMLTHLSLAENALKDEGAKHIWNALPHLRCPLQR
LVLRKCDLTFNCCQDMISALCKNKTLKSLDLSFNSLKDDGVILLCEALKNPDCTLQILEL
ENCLFTSICCQAMASMLRKNQHLRHLDLSKNAIGVYGILTLCEAFSSQKKREEVIFCIPA
WTRITSFSPTPHPPDFTGKSDCLSQINP

Sequence length

1048

Interactions

View interactions

NLRP8 (NLR family pyrin domain containing 8)