ZNF491 (zinc finger protein 491)

Gene

• Entrez ID: 126069
• Gene name: Zinc finger protein 491
• Gene symbol: ZNF491
• Synonyms (NCBI Gene): -
• Chromosome: 19
• Chromosome location: 19p13.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT517639	hsa-miR-4438	PAR-CLIP	23446348
MIRT517638	hsa-miR-512-3p	PAR-CLIP	23446348
MIRT517637	hsa-miR-500b-3p	PAR-CLIP	23446348
MIRT517636	hsa-miR-4427	PAR-CLIP	23446348
MIRT517635	hsa-miR-3130-3p	PAR-CLIP	23446348
MIRT517634	hsa-miR-7155-5p	PAR-CLIP	23446348
MIRT517633	hsa-miR-4252	PAR-CLIP	23446348
MIRT517631	hsa-miR-4731-5p	PAR-CLIP	23446348
MIRT517632	hsa-miR-5589-5p	PAR-CLIP	23446348
MIRT517630	hsa-miR-193b-5p	PAR-CLIP	23446348
MIRT517629	hsa-miR-5095	PAR-CLIP	23446348
MIRT517628	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT517627	hsa-miR-6807-5p	PAR-CLIP	23446348
MIRT517626	hsa-miR-3170	PAR-CLIP	23446348
MIRT517625	hsa-miR-6855-5p	PAR-CLIP	23446348
MIRT446765	hsa-miR-320e	PAR-CLIP	22100165
MIRT446764	hsa-miR-6757-5p	PAR-CLIP	22100165
MIRT446763	hsa-miR-3192-5p	PAR-CLIP	22100165
MIRT446762	hsa-miR-5008-5p	PAR-CLIP	22100165
MIRT446761	hsa-miR-6089	PAR-CLIP	22100165
MIRT446760	hsa-miR-1249-5p	PAR-CLIP	22100165
MIRT446759	hsa-miR-6797-5p	PAR-CLIP	22100165
MIRT446757	hsa-miR-7106-5p	PAR-CLIP	22100165
MIRT446758	hsa-miR-149-3p	PAR-CLIP	22100165
MIRT446756	hsa-miR-4728-5p	PAR-CLIP	22100165
MIRT446755	hsa-miR-6785-5p	PAR-CLIP	22100165
MIRT446754	hsa-miR-6883-5p	PAR-CLIP	22100165
MIRT446753	hsa-miR-6799-5p	PAR-CLIP	22100165
MIRT446752	hsa-miR-6765-5p	PAR-CLIP	22100165
MIRT446751	hsa-miR-1273e	PAR-CLIP	22100165
MIRT446750	hsa-miR-1273h-5p	PAR-CLIP	22100165
MIRT446749	hsa-miR-30b-3p	PAR-CLIP	22100165
MIRT446748	hsa-miR-3689a-3p	PAR-CLIP	22100165
MIRT446747	hsa-miR-3689b-3p	PAR-CLIP	22100165
MIRT446746	hsa-miR-3689c	PAR-CLIP	22100165
MIRT446745	hsa-miR-6779-5p	PAR-CLIP	22100165
MIRT446744	hsa-miR-6780a-5p	PAR-CLIP	22100165
MIRT446743	hsa-miR-498	PAR-CLIP	22100165
MIRT446742	hsa-miR-1304-5p	PAR-CLIP	22100165
MIRT517639	hsa-miR-4438	PAR-CLIP	23446348
MIRT517638	hsa-miR-512-3p	PAR-CLIP	23446348
MIRT517637	hsa-miR-500b-3p	PAR-CLIP	23446348
MIRT517636	hsa-miR-4427	PAR-CLIP	23446348
MIRT517635	hsa-miR-3130-3p	PAR-CLIP	23446348
MIRT517634	hsa-miR-7155-5p	PAR-CLIP	23446348
MIRT517633	hsa-miR-4252	PAR-CLIP	23446348
MIRT517631	hsa-miR-4731-5p	PAR-CLIP	23446348
MIRT517632	hsa-miR-5589-5p	PAR-CLIP	23446348
MIRT517630	hsa-miR-193b-5p	PAR-CLIP	23446348
MIRT517629	hsa-miR-5095	PAR-CLIP	23446348
MIRT517628	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT517627	hsa-miR-6807-5p	PAR-CLIP	23446348
MIRT517626	hsa-miR-3170	PAR-CLIP	23446348
MIRT517625	hsa-miR-6855-5p	PAR-CLIP	23446348
MIRT446765	hsa-miR-320e	PAR-CLIP	22100165
MIRT446764	hsa-miR-6757-5p	PAR-CLIP	22100165
MIRT446763	hsa-miR-3192-5p	PAR-CLIP	22100165
MIRT446762	hsa-miR-5008-5p	PAR-CLIP	22100165
MIRT446761	hsa-miR-6089	PAR-CLIP	22100165
MIRT446760	hsa-miR-1249-5p	PAR-CLIP	22100165
MIRT446759	hsa-miR-6797-5p	PAR-CLIP	22100165
MIRT446757	hsa-miR-7106-5p	PAR-CLIP	22100165
MIRT446758	hsa-miR-149-3p	PAR-CLIP	22100165
MIRT446756	hsa-miR-4728-5p	PAR-CLIP	22100165
MIRT446755	hsa-miR-6785-5p	PAR-CLIP	22100165
MIRT446754	hsa-miR-6883-5p	PAR-CLIP	22100165
MIRT446753	hsa-miR-6799-5p	PAR-CLIP	22100165
MIRT446752	hsa-miR-6765-5p	PAR-CLIP	22100165
MIRT446751	hsa-miR-1273e	PAR-CLIP	22100165
MIRT446750	hsa-miR-1273h-5p	PAR-CLIP	22100165
MIRT446749	hsa-miR-30b-3p	PAR-CLIP	22100165
MIRT446748	hsa-miR-3689a-3p	PAR-CLIP	22100165
MIRT446747	hsa-miR-3689b-3p	PAR-CLIP	22100165
MIRT446746	hsa-miR-3689c	PAR-CLIP	22100165
MIRT446745	hsa-miR-6779-5p	PAR-CLIP	22100165
MIRT446744	hsa-miR-6780a-5p	PAR-CLIP	22100165
MIRT446743	hsa-miR-498	PAR-CLIP	22100165
MIRT446742	hsa-miR-1304-5p	PAR-CLIP	22100165
MIRT1526440	hsa-miR-1208	CLIP-seq
MIRT1526441	hsa-miR-1224-3p	CLIP-seq
MIRT1526442	hsa-miR-1273f	CLIP-seq
MIRT1526443	hsa-miR-129-5p	CLIP-seq
MIRT1526444	hsa-miR-137	CLIP-seq
MIRT1526445	hsa-miR-18a	CLIP-seq
MIRT1526446	hsa-miR-18b	CLIP-seq
MIRT1526447	hsa-miR-198	CLIP-seq
MIRT1526448	hsa-miR-24	CLIP-seq
MIRT1526449	hsa-miR-302a	CLIP-seq
MIRT1526450	hsa-miR-302b	CLIP-seq
MIRT1526451	hsa-miR-302c	CLIP-seq
MIRT1526452	hsa-miR-302d	CLIP-seq
MIRT1526453	hsa-miR-302e	CLIP-seq
MIRT1526454	hsa-miR-30a	CLIP-seq
MIRT1526455	hsa-miR-30b	CLIP-seq
MIRT1526456	hsa-miR-30c	CLIP-seq
MIRT1526457	hsa-miR-30d	CLIP-seq
MIRT1526458	hsa-miR-30e	CLIP-seq
MIRT1526459	hsa-miR-3135b	CLIP-seq
MIRT1526460	hsa-miR-3144-5p	CLIP-seq
MIRT1526461	hsa-miR-3187-3p	CLIP-seq
MIRT1526462	hsa-miR-3191	CLIP-seq
MIRT1526463	hsa-miR-3652	CLIP-seq
MIRT1526464	hsa-miR-3655	CLIP-seq
MIRT1526465	hsa-miR-3672	CLIP-seq
MIRT1526466	hsa-miR-371-5p	CLIP-seq
MIRT1526467	hsa-miR-371b-5p	CLIP-seq
MIRT1526468	hsa-miR-372	CLIP-seq
MIRT1526469	hsa-miR-373	CLIP-seq
MIRT1526470	hsa-miR-411	CLIP-seq
MIRT1526471	hsa-miR-4284	CLIP-seq
MIRT1526472	hsa-miR-4314	CLIP-seq
MIRT1526473	hsa-miR-4420	CLIP-seq
MIRT1526474	hsa-miR-4430	CLIP-seq
MIRT1526475	hsa-miR-4435	CLIP-seq
MIRT1526476	hsa-miR-4454	CLIP-seq
MIRT1526477	hsa-miR-4491	CLIP-seq
MIRT1526478	hsa-miR-4495	CLIP-seq
MIRT1526479	hsa-miR-4633-3p	CLIP-seq
MIRT1526480	hsa-miR-4645-5p	CLIP-seq
MIRT1526481	hsa-miR-4652-5p	CLIP-seq
MIRT1526482	hsa-miR-4657	CLIP-seq
MIRT1526483	hsa-miR-4667-5p	CLIP-seq
MIRT1526484	hsa-miR-4673	CLIP-seq
MIRT1526485	hsa-miR-4700-5p	CLIP-seq
MIRT1526486	hsa-miR-4701-5p	CLIP-seq
MIRT1526487	hsa-miR-4735-3p	CLIP-seq
MIRT1526488	hsa-miR-4755-3p	CLIP-seq
MIRT1526489	hsa-miR-4797-5p	CLIP-seq
MIRT1526490	hsa-miR-496	CLIP-seq
MIRT1526491	hsa-miR-520a-3p	CLIP-seq
MIRT1526492	hsa-miR-520b	CLIP-seq
MIRT1526493	hsa-miR-520c-3p	CLIP-seq
MIRT1526494	hsa-miR-520d-3p	CLIP-seq
MIRT1526495	hsa-miR-520e	CLIP-seq
MIRT1526496	hsa-miR-548s	CLIP-seq
MIRT1526497	hsa-miR-588	CLIP-seq
MIRT1526498	hsa-miR-637	CLIP-seq
MIRT1526499	hsa-miR-892a	CLIP-seq
MIRT2159107	hsa-miR-10a	CLIP-seq
MIRT2159108	hsa-miR-10b	CLIP-seq
MIRT1526441	hsa-miR-1224-3p	CLIP-seq
MIRT1526447	hsa-miR-198	CLIP-seq
MIRT1526459	hsa-miR-3135b	CLIP-seq
MIRT2159109	hsa-miR-339-5p	CLIP-seq
MIRT1526463	hsa-miR-3652	CLIP-seq
MIRT1526464	hsa-miR-3655	CLIP-seq
MIRT1526466	hsa-miR-371-5p	CLIP-seq
MIRT1526467	hsa-miR-371b-5p	CLIP-seq
MIRT2159110	hsa-miR-4421	CLIP-seq
MIRT1526474	hsa-miR-4430	CLIP-seq
MIRT1526476	hsa-miR-4454	CLIP-seq
MIRT2159111	hsa-miR-4474-5p	CLIP-seq
MIRT1526480	hsa-miR-4645-5p	CLIP-seq
MIRT1526484	hsa-miR-4673	CLIP-seq
MIRT2159112	hsa-miR-4725-5p	CLIP-seq
MIRT2159113	hsa-miR-504	CLIP-seq
MIRT2159114	hsa-miR-593	CLIP-seq
MIRT2378512	hsa-miR-106a	CLIP-seq
MIRT2378513	hsa-miR-106b	CLIP-seq
MIRT2159107	hsa-miR-10a	CLIP-seq
MIRT2159108	hsa-miR-10b	CLIP-seq
MIRT1526441	hsa-miR-1224-3p	CLIP-seq
MIRT2378514	hsa-miR-1234	CLIP-seq
MIRT2378515	hsa-miR-1261	CLIP-seq
MIRT2378516	hsa-miR-1304	CLIP-seq
MIRT2378517	hsa-miR-141	CLIP-seq
MIRT2378518	hsa-miR-150	CLIP-seq
MIRT2378519	hsa-miR-17	CLIP-seq
MIRT2378520	hsa-miR-1976	CLIP-seq
MIRT1526447	hsa-miR-198	CLIP-seq
MIRT2378521	hsa-miR-200a	CLIP-seq
MIRT2378522	hsa-miR-20a	CLIP-seq
MIRT2378523	hsa-miR-20b	CLIP-seq
MIRT1526448	hsa-miR-24	CLIP-seq
MIRT1526449	hsa-miR-302a	CLIP-seq
MIRT1526450	hsa-miR-302b	CLIP-seq
MIRT1526451	hsa-miR-302c	CLIP-seq
MIRT1526452	hsa-miR-302d	CLIP-seq
MIRT1526453	hsa-miR-302e	CLIP-seq
MIRT2378524	hsa-miR-3117-5p	CLIP-seq
MIRT1526459	hsa-miR-3135b	CLIP-seq
MIRT2378525	hsa-miR-3174	CLIP-seq
MIRT2378526	hsa-miR-3192	CLIP-seq
MIRT2159109	hsa-miR-339-5p	CLIP-seq
MIRT1526463	hsa-miR-3652	CLIP-seq
MIRT2378527	hsa-miR-3654	CLIP-seq
MIRT1526464	hsa-miR-3655	CLIP-seq
MIRT2378528	hsa-miR-3690	CLIP-seq
MIRT1526468	hsa-miR-372	CLIP-seq
MIRT1526469	hsa-miR-373	CLIP-seq
MIRT2378529	hsa-miR-4261	CLIP-seq
MIRT2378530	hsa-miR-4279	CLIP-seq
MIRT1526471	hsa-miR-4284	CLIP-seq
MIRT2159110	hsa-miR-4421	CLIP-seq
MIRT1526474	hsa-miR-4430	CLIP-seq
MIRT2378531	hsa-miR-4433	CLIP-seq
MIRT2378532	hsa-miR-4459	CLIP-seq
MIRT2378533	hsa-miR-4496	CLIP-seq
MIRT2378534	hsa-miR-4638-3p	CLIP-seq
MIRT1526480	hsa-miR-4645-5p	CLIP-seq
MIRT2378535	hsa-miR-4662a-3p	CLIP-seq
MIRT1526484	hsa-miR-4673	CLIP-seq
MIRT2378536	hsa-miR-4722-3p	CLIP-seq
MIRT2159112	hsa-miR-4725-5p	CLIP-seq
MIRT2378537	hsa-miR-4740-3p	CLIP-seq
MIRT2378538	hsa-miR-4768-3p	CLIP-seq
MIRT2378539	hsa-miR-4786-5p	CLIP-seq
MIRT2378540	hsa-miR-490-3p	CLIP-seq
MIRT2159113	hsa-miR-504	CLIP-seq
MIRT2378541	hsa-miR-519d	CLIP-seq
MIRT1526491	hsa-miR-520a-3p	CLIP-seq
MIRT1526492	hsa-miR-520b	CLIP-seq
MIRT1526493	hsa-miR-520c-3p	CLIP-seq
MIRT1526494	hsa-miR-520d-3p	CLIP-seq
MIRT1526495	hsa-miR-520e	CLIP-seq
MIRT2378542	hsa-miR-520g	CLIP-seq
MIRT2378543	hsa-miR-520h	CLIP-seq
MIRT2378544	hsa-miR-552	CLIP-seq
MIRT2159114	hsa-miR-593	CLIP-seq
MIRT2378545	hsa-miR-619	CLIP-seq
MIRT2378546	hsa-miR-665	CLIP-seq
MIRT2378547	hsa-miR-769-5p	CLIP-seq
MIRT2378548	hsa-miR-921	CLIP-seq
MIRT2378549	hsa-miR-93	CLIP-seq
MIRT2378512	hsa-miR-106a	CLIP-seq
MIRT2378513	hsa-miR-106b	CLIP-seq
MIRT2378519	hsa-miR-17	CLIP-seq
MIRT2378522	hsa-miR-20a	CLIP-seq
MIRT2378523	hsa-miR-20b	CLIP-seq
MIRT1526449	hsa-miR-302a	CLIP-seq
MIRT1526450	hsa-miR-302b	CLIP-seq
MIRT1526451	hsa-miR-302c	CLIP-seq
MIRT1526452	hsa-miR-302d	CLIP-seq
MIRT1526453	hsa-miR-302e	CLIP-seq
MIRT1526468	hsa-miR-372	CLIP-seq
MIRT1526469	hsa-miR-373	CLIP-seq
MIRT2378541	hsa-miR-519d	CLIP-seq
MIRT1526491	hsa-miR-520a-3p	CLIP-seq
MIRT1526492	hsa-miR-520b	CLIP-seq
MIRT1526493	hsa-miR-520c-3p	CLIP-seq
MIRT1526494	hsa-miR-520d-3p	CLIP-seq
MIRT1526495	hsa-miR-520e	CLIP-seq
MIRT2378542	hsa-miR-520g	CLIP-seq
MIRT2378543	hsa-miR-520h	CLIP-seq
MIRT2397582	hsa-miR-9	CLIP-seq
MIRT2378549	hsa-miR-93	CLIP-seq
MIRT2464289	hsa-miR-1915	CLIP-seq
MIRT2378531	hsa-miR-4433	CLIP-seq
MIRT2378532	hsa-miR-4459	CLIP-seq
MIRT2464290	hsa-miR-4726-3p	CLIP-seq
MIRT2378538	hsa-miR-4768-3p	CLIP-seq
MIRT2464289	hsa-miR-1915	CLIP-seq
MIRT2378520	hsa-miR-1976	CLIP-seq
MIRT1526447	hsa-miR-198	CLIP-seq
MIRT1526448	hsa-miR-24	CLIP-seq
MIRT1526459	hsa-miR-3135b	CLIP-seq
MIRT1526463	hsa-miR-3652	CLIP-seq
MIRT1526464	hsa-miR-3655	CLIP-seq
MIRT2378530	hsa-miR-4279	CLIP-seq
MIRT1526471	hsa-miR-4284	CLIP-seq
MIRT1526474	hsa-miR-4430	CLIP-seq
MIRT2378531	hsa-miR-4433	CLIP-seq
MIRT2378532	hsa-miR-4459	CLIP-seq
MIRT1526480	hsa-miR-4645-5p	CLIP-seq
MIRT1526484	hsa-miR-4673	CLIP-seq
MIRT2378536	hsa-miR-4722-3p	CLIP-seq
MIRT2464290	hsa-miR-4726-3p	CLIP-seq
MIRT2378537	hsa-miR-4740-3p	CLIP-seq
MIRT2378538	hsa-miR-4768-3p	CLIP-seq
MIRT2670792	hsa-miR-4772-3p	CLIP-seq
MIRT2670793	hsa-miR-941	CLIP-seq
MIRT1526447	hsa-miR-198	CLIP-seq
MIRT1526448	hsa-miR-24	CLIP-seq
MIRT1526459	hsa-miR-3135b	CLIP-seq
MIRT1526463	hsa-miR-3652	CLIP-seq
MIRT1526464	hsa-miR-3655	CLIP-seq
MIRT1526471	hsa-miR-4284	CLIP-seq
MIRT1526474	hsa-miR-4430	CLIP-seq
MIRT1526480	hsa-miR-4645-5p	CLIP-seq
MIRT1526484	hsa-miR-4673	CLIP-seq
MIRT2670792	hsa-miR-4772-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8N8L2
• Protein name: Zinc finger protein 491
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	187 → 209	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	215 → 237	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	271 → 293	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	411 → 433	Zinc finger, C2H2 type	Domain

• Sequence:

  MGERLFESAEGSQCGETFTQVPEDMLNKKTLPGVKSCESGTCGEIFMGYSSFNRNIRTDT
  GHQPHKCQKFLEKPYKHKQRRKALSHSHCFRTHERPHTREKPFDCKECEKSFISPASIRR
  YMVTHSGDGPYKCKFCGKALDCLSLYLTHERTHTGEKRYECKQCGKAFSWHSSVRIHERT
  HTGEKPYECKECGKSFNFSSSFRRHERTHTGEKPYKCKECGKAFNCPSSFHRHERTHTGE
  KPYECKLYGKALSRLISFRRHMRMHTGERPHKCKICGKAFYSPSSFQRHERSHTGEKPYK
  CKQCGKAFTCSTSFQYHERTHTGEKPDGCKQCGKAFRSAKYIRIHGRTHTGEKPYECKQC
  GKAFHCVSSFHRHERTHAGEKPYECKHCGKAFTCSIYIRIHERIHTGEKPYQCKECGKAF
  IRSSYCRKHERTHTINI

• Sequence length: 437

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations