Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
125950
Gene name Gene Name - the full gene name approved by the HGNC.
Ribonucleoprotein, PTB binding 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RAVER1
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19p13.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT016348 hsa-miR-193b-3p Proteomics 21512034
MIRT022658 hsa-miR-124-3p Proteomics;Microarray 18668037
MIRT052550 hsa-let-7a-5p CLASH 23622248
MIRT049468 hsa-miR-92a-3p CLASH 23622248
MIRT044108 hsa-miR-361-5p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003676 Function Nucleic acid binding IEA
GO:0003723 Function RNA binding HDA 22681889
GO:0003723 Function RNA binding IBA
GO:0003723 Function RNA binding IEA
GO:0005515 Function Protein binding IPI 18377426, 19523901, 32296183, 33961781, 34819669
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
609950 30296 ENSG00000161847
Protein
UniProt ID Q8IY67
Protein name Ribonucleoprotein PTB-binding 1 (Protein raver-1)
Protein function Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).
PDB 3H2U , 3H2V , 3SMZ , 3VF0
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00076 RRM_1 61 124 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 134 204 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 224 293 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
Sequence
MAADVSVTHRPPLSPKSGAEVEAGDAAERRAPEEELPPLDPEEIRKRLEHTERQFRNRRK
ILIRGLPGDVTNQEVHDLLSDYELKYCFVDKYKGTAFVTLLNGEQAEAAINAFHQSRLRE
RELS
VQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEY
MKKDSAARAKSDLLGKPLGPRTLY
VHWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCR
ALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLR
VSFCAPG
PPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSAGGKQG
LLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPLLGELPA
GGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLRGSGLRGPL
SHFYSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHSHLLKVRAGG
GDMQGWEAPAPQRPLTRPALPSVSRPHWAARNAALPTCCPRPSPAQKAAMWASTPRASAA
TTRTPT
Sequence length 606
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Rheumatoid arthritis Rheumatoid arthritis N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
COVID 19 Associate 37567834
Craniopharyngioma Associate 40581690
Death Associate 35134262
Liver Cirrhosis Alcoholic Associate 35134262
Neoplasms Inhibit 40581690