Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
124930
Gene name Gene Name - the full gene name approved by the HGNC.
Ankyrin repeat domain 13B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ANKRD13B
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q11.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT003948 hsa-miR-373-3p Microarray 15685193
MIRT040994 hsa-miR-505-3p CLASH 23622248
MIRT494798 hsa-miR-203a-3p PAR-CLIP 20371350
MIRT494797 hsa-miR-6085 PAR-CLIP 20371350
MIRT494796 hsa-miR-6813-5p PAR-CLIP 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0002091 Process Negative regulation of receptor internalization IMP 22298428
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005737 Component Cytoplasm IDA 22298428
GO:0005769 Component Early endosome IDA 22298428
GO:0005770 Component Late endosome IDA 22298428
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
615124 26363 ENSG00000198720
Protein
UniProt ID Q86YJ7
Protein name Ankyrin repeat domain-containing protein 13B
Protein function Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated E
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF12796 Ank_2 18 110 Ankyrin repeats (3 copies) Repeat
PF11904 GPCR_chapero_1 163 490 GPCR-chaperone Domain
Sequence
Sequence length 626
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Coronary artery disease Coronary Artery Disease rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs1555800701, rs1215189537 29212778