OVCA2 (OVCA2 serine hydrolase domain containing)

Gene

• Entrez ID: 124641
• Gene name: OVCA2 serine hydrolase domain containing
• Gene symbol: OVCA2
• Synonyms (NCBI Gene): -
• Chromosome: 17
• Chromosome location: 17p13.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020587	hsa-miR-155-5p	Proteomics	18668040
MIRT1208299	hsa-miR-1255a	CLIP-seq
MIRT1208300	hsa-miR-1255b	CLIP-seq
MIRT1208301	hsa-miR-1343	CLIP-seq
MIRT1208302	hsa-miR-3174	CLIP-seq
MIRT1208303	hsa-miR-3192	CLIP-seq
MIRT1208304	hsa-miR-3616-3p	CLIP-seq
MIRT1208305	hsa-miR-3622b-5p	CLIP-seq
MIRT1208306	hsa-miR-3689a-3p	CLIP-seq
MIRT1208307	hsa-miR-3689c	CLIP-seq
MIRT1208308	hsa-miR-4253	CLIP-seq
MIRT1208309	hsa-miR-4481	CLIP-seq
MIRT1208310	hsa-miR-4519	CLIP-seq
MIRT1208311	hsa-miR-4728-5p	CLIP-seq
MIRT1208312	hsa-miR-4745-5p	CLIP-seq
MIRT1208313	hsa-miR-4758-5p	CLIP-seq
MIRT1208314	hsa-miR-4761-3p	CLIP-seq
MIRT1208315	hsa-miR-490-5p	CLIP-seq
MIRT2059837	hsa-miR-2355-5p	CLIP-seq
MIRT2059838	hsa-miR-4297	CLIP-seq
MIRT2059839	hsa-miR-582-3p	CLIP-seq
MIRT2586315	hsa-miR-1207-5p	CLIP-seq
MIRT2586316	hsa-miR-1245b-5p	CLIP-seq
MIRT2586317	hsa-miR-218	CLIP-seq
MIRT2586318	hsa-miR-3127-3p	CLIP-seq
MIRT2586319	hsa-miR-3142	CLIP-seq
MIRT2586320	hsa-miR-3918	CLIP-seq
MIRT2586321	hsa-miR-4312	CLIP-seq
MIRT2586322	hsa-miR-4436b-3p	CLIP-seq
MIRT2586323	hsa-miR-4457	CLIP-seq
MIRT2586324	hsa-miR-4659a-3p	CLIP-seq
MIRT2586325	hsa-miR-4659b-3p	CLIP-seq
MIRT2586326	hsa-miR-4753-5p	CLIP-seq
MIRT2586327	hsa-miR-4763-3p	CLIP-seq
MIRT2586328	hsa-miR-5096	CLIP-seq
MIRT2586329	hsa-miR-513b	CLIP-seq
MIRT2586330	hsa-miR-515-5p	CLIP-seq
MIRT2586331	hsa-miR-664	CLIP-seq
MIRT2586332	hsa-miR-885-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	16368187
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0016787	Function	Hydrolase activity	IBA
GO:0016787	Function	Hydrolase activity	IEA
GO:0016787	Function	Hydrolase activity	NAS	11979432
GO:0032526	Process	Response to retinoic acid	IDA	11979432
GO:0052689	Function	Carboxylic ester hydrolase activity	IEA
GO:0106435	Function	Carboxylesterase activity	IDA	32182256
GO:0106435	Function	Carboxylesterase activity	IEA

Other IDs

• MIM: 607896
• HGNC: 24203
• e!Ensembl: ENSG00000262664

Protein

• UniProt ID: Q8WZ82
• Protein name: Esterase OVCA2 (EC 3.1.1.1) (OVCA2 serine hydrolase domain-containing protein) (Ovarian cancer-associated gene 2 protein)
• Protein function: Exhibits ester hydrolase activity with a strong preference for long-chain alkyl ester substrates and high selectivity against a variety of short, branched, and substituted esters. Is able to hydrolyze ester bonds within a wide range of p-nitroph
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03959	FSH1	1 → 218	Serine hydrolase (FSH1)	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:11979432, ECO:0000269|PubMed:8616839}.
• Sequence:

  MAAQRPLRVLCLAGFRQSERGFREKTGALRKALRGRAELVCLSGPHPVPDPPGPEGARSD
  FGSCPPEEQPRGWWFSEQEADVFSALEEPAVCRGLEESLGMVAQALNRLGPFDGLLGFSQ
  GAALAALVCALGQAGDPRFPLPRFILLVSGFCPRGIGFKESILQRPLSLPSLHVFGDTDK
  VIPSQESVQLASQFPGAITLTHSGGHFIPAAAPQRQAYLKFLDQFAE

• Sequence length: 227