ZPBP2 (zona pellucida binding protein 2)

Gene

• Entrez ID: 124626
• Gene name: Zona pellucida binding protein 2
• Gene symbol: ZPBP2
• Synonyms (NCBI Gene): ZPBPL
• Chromosome: 17
• Chromosome location: 17q21.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017875	hsa-miR-335-5p	Microarray	18185580
MIRT1543373	hsa-miR-185	CLIP-seq
MIRT1543374	hsa-miR-4306	CLIP-seq
MIRT1543375	hsa-miR-4644	CLIP-seq
MIRT1543376	hsa-miR-4802-5p	CLIP-seq
MIRT2163954	hsa-miR-1323	CLIP-seq
MIRT2163955	hsa-miR-3148	CLIP-seq
MIRT2163956	hsa-miR-3978	CLIP-seq
MIRT2163957	hsa-miR-548a-3p	CLIP-seq
MIRT2163958	hsa-miR-548an	CLIP-seq
MIRT2163959	hsa-miR-548e	CLIP-seq
MIRT2163960	hsa-miR-548f	CLIP-seq
MIRT2163961	hsa-miR-548g	CLIP-seq
MIRT2163962	hsa-miR-548o	CLIP-seq
MIRT2383119	hsa-miR-3120-3p	CLIP-seq
MIRT2383120	hsa-miR-331-5p	CLIP-seq
MIRT2383121	hsa-miR-3617	CLIP-seq
MIRT2383122	hsa-miR-3914	CLIP-seq
MIRT2383123	hsa-miR-3928	CLIP-seq
MIRT2383124	hsa-miR-4672	CLIP-seq
MIRT2383125	hsa-miR-4802-3p	CLIP-seq
MIRT1543376	hsa-miR-4802-5p	CLIP-seq
MIRT2383126	hsa-miR-641	CLIP-seq
MIRT2383127	hsa-miR-765	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001669	Component	Acrosomal vesicle	IBA
GO:0001669	Component	Acrosomal vesicle	IEA
GO:0001675	Process	Acrosome assembly	IBA
GO:0001675	Process	Acrosome assembly	IEA
GO:0002199	Component	Zona pellucida receptor complex	IBA
GO:0002199	Component	Zona pellucida receptor complex	IEA
GO:0002638	Process	Negative regulation of immunoglobulin production	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0005634	Component	Nucleus	HDA	21630459
GO:0006665	Process	Sphingolipid metabolic process	IEA
GO:0007339	Process	Binding of sperm to zona pellucida	IBA
GO:0007339	Process	Binding of sperm to zona pellucida	IEA
GO:0007339	Process	Binding of sperm to zona pellucida	IEA
GO:0016020	Component	Membrane	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0032922	Process	Circadian regulation of gene expression	IEA
GO:0044297	Component	Cell body	IEA
GO:0046466	Process	Membrane lipid catabolic process	IEA

Other IDs

• MIM: 608499
• HGNC: 20678
• e!Ensembl: ENSG00000186075

Protein

• UniProt ID: Q6X784
• Protein name: Zona pellucida-binding protein 2 (ZPBP-like protein)
• Protein function: Is implicated in sperm-oocyte interaction during fertilization.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07354	Sp38	150 → 327	Zona-pellucida-binding protein (Sp38)	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed specifically in testis. {ECO:0000269|PubMed:17664285}.
• Sequence:

  MMRTCVLLSAVLWCLTGVQCPRFTLFNKKGFIYGKTGQPDKIYVELHQNSPVLICMDFKL
  SKKEIVDPTYLWIGPNEKTLTGNNRINITETGQLMVKDFLEPLSGLYTCTLSYKTVKAET
  QEEKTVKKRYDFMVFAYREPDYSYQMAVRFTTRSCIGRYNDVFFRVLKKILDSLISDLSC
  HVIEPSYKCHSVEIPEHGLIHELFIAFQVNPFAPGWKGACNGSVDCEDTTNHNILQARDR
  IEDFFRSQAYIFYHNFNKTLPAMHFVDHSLQVVRLDSCRPGFGKNERLHSNCASCCVVCS
  PATFSPDVNVTCQTCVSVLTYGAKSCPQTSNKNQQYED

• Sequence length: 338