Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
124359
Gene name Gene Name - the full gene name approved by the HGNC.
Chromodomain Y like 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CDYL2
Synonyms (NCBI Gene) Gene synonyms aliases
PCCP1
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16q23.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT882848 hsa-miR-1178 CLIP-seq
MIRT882849 hsa-miR-1197 CLIP-seq
MIRT882850 hsa-miR-1299 CLIP-seq
MIRT882851 hsa-miR-1343 CLIP-seq
MIRT882852 hsa-miR-3127-3p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003714 Function Transcription corepressor activity IBA 21873635
GO:0003824 Function Catalytic activity IEA
GO:0005515 Function Protein binding IPI 17577209, 23455924, 32296183
GO:0005634 Component Nucleus IBA 21873635
GO:0045892 Process Negative regulation of transcription, DNA-templated IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
618816 23030 ENSG00000166446
Protein
UniProt ID Q8N8U2
Protein name Chromodomain Y-like protein 2 (CDY-like 2)
PDB 2MJ8 , 4HAE , 5JJZ , 6V2D , 6V2H , 6V3N , 6V8W , 8SP6
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00385 Chromo 7 57 Chromo (CHRromatin Organisation MOdifier) domain Domain
PF00378 ECH_1 255 502 Enoyl-CoA hydratase/isomerase Domain
Tissue specificity TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:12837688}.
Sequence
MASGDLYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHM
SKDKRIKSGKQSSTSKLLRDSRGPSVEKLSHRPSDPGKSKGTSHKRKRINPPLAKPKKGY
SGKPSSGGDRATKTVSYRTTPSGLQIMPLKKSQNGMENGDAGSEKDERHFGNGSHQPGLD
LNDHVGEQDMGECDVNHATLAENGLGSALTNGGLNLHSPVKRKLEAEKDYVFDKRLRYSV
RQNESNCRFRDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDDSKLLLL
SAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPALGL
GASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQ
EACSRGLVSQVFWPTTFSQEVMLRVKEMASCSAVVLEESKCLVRSFLKSVLEDVNEKECL
MLKQLWSSSKGLDSLFSYLQDK
IYEV
Sequence length 506
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Breast cancer Malignant neoplasm of breast rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158
View all (309 more)
23535729
Breast carcinoma Breast Carcinoma rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451
View all (71 more)
29059683, 23535729, 25751625
Inflammatory bowel disease Inflammatory Bowel Diseases rs137853579, rs137853580, rs121909601, rs149491038, rs368287711, rs387907326, rs587777338, rs758439420, rs1329427406, rs1264862631, rs1192830343, rs1373354533, rs1419560997, rs1591263883, rs1989014468 27569725
Unknown
Disease term Disease name Evidence References Source
Inflammatory Bowel Disease Inflammatory Bowel Disease GWAS
Prostate cancer Prostate cancer Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population. GWAS, CBGDA
Ulcerative colitis Ulcerative colitis GWAS
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 23593120, 30594178
Disease Associate 36658409