CDYL2 (chromodomain Y like 2)

Gene

• Entrez ID: 124359
• Gene name: Chromodomain Y like 2
• Gene symbol: CDYL2
• Synonyms (NCBI Gene): PCCP1
• Chromosome: 16
• Chromosome location: 16q23.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT882848	hsa-miR-1178	CLIP-seq
MIRT882849	hsa-miR-1197	CLIP-seq
MIRT882850	hsa-miR-1299	CLIP-seq
MIRT882851	hsa-miR-1343	CLIP-seq
MIRT882852	hsa-miR-3127-3p	CLIP-seq
MIRT882853	hsa-miR-3173-3p	CLIP-seq
MIRT882854	hsa-miR-3545-5p	CLIP-seq
MIRT882855	hsa-miR-3667-3p	CLIP-seq
MIRT882856	hsa-miR-3690	CLIP-seq
MIRT882857	hsa-miR-3691-3p	CLIP-seq
MIRT882858	hsa-miR-3926	CLIP-seq
MIRT882859	hsa-miR-3934	CLIP-seq
MIRT882860	hsa-miR-3941	CLIP-seq
MIRT882861	hsa-miR-4254	CLIP-seq
MIRT882862	hsa-miR-4291	CLIP-seq
MIRT882863	hsa-miR-4480	CLIP-seq
MIRT882864	hsa-miR-4527	CLIP-seq
MIRT882865	hsa-miR-466	CLIP-seq
MIRT882866	hsa-miR-4672	CLIP-seq
MIRT882867	hsa-miR-4731-3p	CLIP-seq
MIRT882868	hsa-miR-4796-3p	CLIP-seq
MIRT882869	hsa-miR-4799-5p	CLIP-seq
MIRT882870	hsa-miR-4801	CLIP-seq
MIRT882871	hsa-miR-545	CLIP-seq
MIRT882872	hsa-miR-548s	CLIP-seq
MIRT882873	hsa-miR-587	CLIP-seq
MIRT882874	hsa-miR-765	CLIP-seq
MIRT882875	hsa-miR-875-3p	CLIP-seq
MIRT882876	hsa-miR-885-5p	CLIP-seq
MIRT1961713	hsa-miR-1207-5p	CLIP-seq
MIRT1961714	hsa-miR-1233	CLIP-seq
MIRT1961715	hsa-miR-1250	CLIP-seq
MIRT1961716	hsa-miR-1275	CLIP-seq
MIRT1961717	hsa-miR-1276	CLIP-seq
MIRT1961718	hsa-miR-1321	CLIP-seq
MIRT882851	hsa-miR-1343	CLIP-seq
MIRT1961719	hsa-miR-208a	CLIP-seq
MIRT1961720	hsa-miR-208b	CLIP-seq
MIRT1961721	hsa-miR-2110	CLIP-seq
MIRT1961722	hsa-miR-2277-3p	CLIP-seq
MIRT1961723	hsa-miR-3126-3p	CLIP-seq
MIRT882852	hsa-miR-3127-3p	CLIP-seq
MIRT1961724	hsa-miR-3153	CLIP-seq
MIRT1961725	hsa-miR-3166	CLIP-seq
MIRT1961726	hsa-miR-3176	CLIP-seq
MIRT1961727	hsa-miR-3189-3p	CLIP-seq
MIRT1961728	hsa-miR-3194-3p	CLIP-seq
MIRT1961729	hsa-miR-3202	CLIP-seq
MIRT1961730	hsa-miR-326	CLIP-seq
MIRT1961731	hsa-miR-330-5p	CLIP-seq
MIRT1961732	hsa-miR-338-5p	CLIP-seq
MIRT1961733	hsa-miR-34b	CLIP-seq
MIRT1961734	hsa-miR-3658	CLIP-seq
MIRT882855	hsa-miR-3667-3p	CLIP-seq
MIRT1961735	hsa-miR-3667-5p	CLIP-seq
MIRT1961736	hsa-miR-3689d	CLIP-seq
MIRT882856	hsa-miR-3690	CLIP-seq
MIRT882857	hsa-miR-3691-3p	CLIP-seq
MIRT1961737	hsa-miR-3922-3p	CLIP-seq
MIRT882858	hsa-miR-3926	CLIP-seq
MIRT1961738	hsa-miR-3940-5p	CLIP-seq
MIRT882861	hsa-miR-4254	CLIP-seq
MIRT1961739	hsa-miR-4257	CLIP-seq
MIRT1961740	hsa-miR-4263	CLIP-seq
MIRT1961741	hsa-miR-4270	CLIP-seq
MIRT1961742	hsa-miR-4271	CLIP-seq
MIRT1961743	hsa-miR-4292	CLIP-seq
MIRT1961744	hsa-miR-4293	CLIP-seq
MIRT1961745	hsa-miR-4311	CLIP-seq
MIRT1961746	hsa-miR-4428	CLIP-seq
MIRT1961747	hsa-miR-4435	CLIP-seq
MIRT1961748	hsa-miR-4436b-3p	CLIP-seq
MIRT1961749	hsa-miR-4441	CLIP-seq
MIRT1961750	hsa-miR-4476	CLIP-seq
MIRT882863	hsa-miR-4480	CLIP-seq
MIRT1961751	hsa-miR-4499	CLIP-seq
MIRT1961752	hsa-miR-4507	CLIP-seq
MIRT1961753	hsa-miR-450b-5p	CLIP-seq
MIRT1961754	hsa-miR-4646-5p	CLIP-seq
MIRT1961755	hsa-miR-4649-3p	CLIP-seq
MIRT1961756	hsa-miR-4665-5p	CLIP-seq
MIRT1961757	hsa-miR-4725-3p	CLIP-seq
MIRT1961758	hsa-miR-4730	CLIP-seq
MIRT1961759	hsa-miR-4739	CLIP-seq
MIRT1961760	hsa-miR-4743	CLIP-seq
MIRT1961761	hsa-miR-4746-3p	CLIP-seq
MIRT1961762	hsa-miR-4747-5p	CLIP-seq
MIRT1961763	hsa-miR-4756-5p	CLIP-seq
MIRT1961764	hsa-miR-4763-3p	CLIP-seq
MIRT882869	hsa-miR-4799-5p	CLIP-seq
MIRT1961765	hsa-miR-486-3p	CLIP-seq
MIRT1961766	hsa-miR-491-5p	CLIP-seq
MIRT1961767	hsa-miR-499-5p	CLIP-seq
MIRT1961768	hsa-miR-515-5p	CLIP-seq
MIRT1961769	hsa-miR-518a-5p	CLIP-seq
MIRT1961770	hsa-miR-527	CLIP-seq
MIRT882872	hsa-miR-548s	CLIP-seq
MIRT1961771	hsa-miR-576-5p	CLIP-seq
MIRT1961772	hsa-miR-583	CLIP-seq
MIRT1961773	hsa-miR-629	CLIP-seq
MIRT1961774	hsa-miR-633	CLIP-seq
MIRT1961775	hsa-miR-636	CLIP-seq
MIRT1961776	hsa-miR-892a	CLIP-seq
MIRT1961714	hsa-miR-1233	CLIP-seq
MIRT1961715	hsa-miR-1250	CLIP-seq
MIRT1961723	hsa-miR-3126-3p	CLIP-seq
MIRT1961725	hsa-miR-3166	CLIP-seq
MIRT1961727	hsa-miR-3189-3p	CLIP-seq
MIRT1961732	hsa-miR-338-5p	CLIP-seq
MIRT1961733	hsa-miR-34b	CLIP-seq
MIRT882857	hsa-miR-3691-3p	CLIP-seq
MIRT2198329	hsa-miR-377	CLIP-seq
MIRT882858	hsa-miR-3926	CLIP-seq
MIRT882859	hsa-miR-3934	CLIP-seq
MIRT1961743	hsa-miR-4292	CLIP-seq
MIRT1961746	hsa-miR-4428	CLIP-seq
MIRT1961748	hsa-miR-4436b-3p	CLIP-seq
MIRT882863	hsa-miR-4480	CLIP-seq
MIRT2198330	hsa-miR-4487	CLIP-seq
MIRT1961751	hsa-miR-4499	CLIP-seq
MIRT1961753	hsa-miR-450b-5p	CLIP-seq
MIRT1961754	hsa-miR-4646-5p	CLIP-seq
MIRT1961755	hsa-miR-4649-3p	CLIP-seq
MIRT1961758	hsa-miR-4730	CLIP-seq
MIRT1961760	hsa-miR-4743	CLIP-seq
MIRT1961761	hsa-miR-4746-3p	CLIP-seq
MIRT1961762	hsa-miR-4747-5p	CLIP-seq
MIRT882869	hsa-miR-4799-5p	CLIP-seq
MIRT1961765	hsa-miR-486-3p	CLIP-seq
MIRT1961769	hsa-miR-518a-5p	CLIP-seq
MIRT1961770	hsa-miR-527	CLIP-seq
MIRT882872	hsa-miR-548s	CLIP-seq
MIRT1961773	hsa-miR-629	CLIP-seq
MIRT1961775	hsa-miR-636	CLIP-seq
MIRT882859	hsa-miR-3934	CLIP-seq
MIRT1961746	hsa-miR-4428	CLIP-seq
MIRT1961751	hsa-miR-4499	CLIP-seq
MIRT1961755	hsa-miR-4649-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003714	Function	Transcription corepressor activity	IBA
GO:0005515	Function	Protein binding	IPI	17577209, 23455924, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006325	Process	Chromatin organization	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IEA
GO:0061628	Function	Histone H3K27me3 reader activity	IEA
GO:0062072	Function	Histone H3K9me2/3 reader activity	IEA

Other IDs

• MIM: 618816
• HGNC: 23030
• e!Ensembl: ENSG00000166446

Protein

• UniProt ID: Q8N8U2
• Protein name: Chromodomain Y-like protein 2 (CDY-like 2)
• PDB: 2MJ8, 4HAE, 5JJZ, 6V2D, 6V2H, 6V3N, 6V8W, 8SP6
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00385	Chromo	7 → 57	Chromo (CHRromatin Organisation MOdifier) domain	Domain
  PF00378	ECH_1	255 → 502	Enoyl-CoA hydratase/isomerase	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:12837688}.
• Sequence:

  MASGDLYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHM
  SKDKRIKSGKQSSTSKLLRDSRGPSVEKLSHRPSDPGKSKGTSHKRKRINPPLAKPKKGY
  SGKPSSGGDRATKTVSYRTTPSGLQIMPLKKSQNGMENGDAGSEKDERHFGNGSHQPGLD
  LNDHVGEQDMGECDVNHATLAENGLGSALTNGGLNLHSPVKRKLEAEKDYVFDKRLRYSV
  RQNESNCRFRDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDDSKLLLL
  SAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPALGL
  GASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQ
  EACSRGLVSQVFWPTTFSQEVMLRVKEMASCSAVVLEESKCLVRSFLKSVLEDVNEKECL
  MLKQLWSSSKGLDSLFSYLQDKIYEV

• Sequence length: 506