Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	1241
Gene name Gene Name - the full gene name approved by the HGNC.	Leukotriene B4 receptor
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LTB4R
Synonyms (NCBI Gene) Gene synonyms aliases	BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q12

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miRTarBase ID	miRNA	Experiments
MIRT1122096	hsa-miR-1207-3p	CLIP-seq
MIRT1122097	hsa-miR-122	CLIP-seq
MIRT1122098	hsa-miR-2117	CLIP-seq
MIRT1122099	hsa-miR-3161	CLIP-seq
MIRT1122100	hsa-miR-371-5p	CLIP-seq
MIRT1122101	hsa-miR-371b-5p	CLIP-seq
MIRT1122102	hsa-miR-4254	CLIP-seq
MIRT1122103	hsa-miR-4273	CLIP-seq
MIRT1122104	hsa-miR-4281	CLIP-seq
MIRT1122105	hsa-miR-4330	CLIP-seq
MIRT1122106	hsa-miR-4449	CLIP-seq
MIRT1122107	hsa-miR-4491	CLIP-seq
MIRT1122108	hsa-miR-4519	CLIP-seq
MIRT1122109	hsa-miR-4532	CLIP-seq
MIRT1122110	hsa-miR-4657	CLIP-seq
MIRT1122111	hsa-miR-4684-3p	CLIP-seq
MIRT1122112	hsa-miR-4754	CLIP-seq
MIRT1122113	hsa-miR-4765	CLIP-seq
MIRT1122114	hsa-miR-490-3p	CLIP-seq
MIRT1122115	hsa-miR-493	CLIP-seq
MIRT1122116	hsa-miR-512-3p	CLIP-seq
MIRT1122117	hsa-miR-513c	CLIP-seq
MIRT1122118	hsa-miR-514b-5p	CLIP-seq
MIRT1122119	hsa-miR-619	CLIP-seq
MIRT1122120	hsa-miR-1179	CLIP-seq
MIRT1122096	hsa-miR-1207-3p	CLIP-seq
MIRT1122121	hsa-miR-149	CLIP-seq
MIRT1122098	hsa-miR-2117	CLIP-seq
MIRT1122122	hsa-miR-24	CLIP-seq
MIRT1122100	hsa-miR-371-5p	CLIP-seq
MIRT1122101	hsa-miR-371b-5p	CLIP-seq
MIRT1122103	hsa-miR-4273	CLIP-seq
MIRT1122123	hsa-miR-4284	CLIP-seq
MIRT1122124	hsa-miR-4727-5p	CLIP-seq
MIRT1122125	hsa-miR-4769-3p	CLIP-seq
MIRT1122117	hsa-miR-513c	CLIP-seq
MIRT1122118	hsa-miR-514b-5p	CLIP-seq
MIRT1122126	hsa-miR-621	CLIP-seq
MIRT1122127	hsa-miR-892b	CLIP-seq
MIRT1122096	hsa-miR-1207-3p	CLIP-seq
MIRT1122098	hsa-miR-2117	CLIP-seq
MIRT1122100	hsa-miR-371-5p	CLIP-seq
MIRT1122101	hsa-miR-371b-5p	CLIP-seq
MIRT1122103	hsa-miR-4273	CLIP-seq
MIRT1122117	hsa-miR-513c	CLIP-seq
MIRT1122118	hsa-miR-514b-5p	CLIP-seq
MIRT2034494	hsa-miR-642a	CLIP-seq
MIRT1122096	hsa-miR-1207-3p	CLIP-seq
MIRT2390388	hsa-miR-1281	CLIP-seq
MIRT1122098	hsa-miR-2117	CLIP-seq
MIRT1122100	hsa-miR-371-5p	CLIP-seq
MIRT1122101	hsa-miR-371b-5p	CLIP-seq
MIRT2390389	hsa-miR-4258	CLIP-seq
MIRT1122103	hsa-miR-4273	CLIP-seq
MIRT1122117	hsa-miR-513c	CLIP-seq
MIRT1122118	hsa-miR-514b-5p	CLIP-seq
MIRT2390390	hsa-miR-532-3p	CLIP-seq
MIRT2390391	hsa-miR-662	CLIP-seq
MIRT2453496	hsa-miR-296-5p	CLIP-seq
MIRT2453497	hsa-miR-3184	CLIP-seq
MIRT2453498	hsa-miR-423-5p	CLIP-seq
MIRT1122104	hsa-miR-4281	CLIP-seq
MIRT1122105	hsa-miR-4330	CLIP-seq
MIRT1122106	hsa-miR-4449	CLIP-seq
MIRT2453499	hsa-miR-4523	CLIP-seq
MIRT1122109	hsa-miR-4532	CLIP-seq
MIRT2453500	hsa-miR-4685-5p	CLIP-seq
MIRT2453501	hsa-miR-4733-3p	CLIP-seq
MIRT2453502	hsa-miR-4758-3p	CLIP-seq
MIRT1122115	hsa-miR-493	CLIP-seq
MIRT2453496	hsa-miR-296-5p	CLIP-seq
MIRT2453497	hsa-miR-3184	CLIP-seq
MIRT2453498	hsa-miR-423-5p	CLIP-seq
MIRT2453499	hsa-miR-4523	CLIP-seq
MIRT2453500	hsa-miR-4685-5p	CLIP-seq
MIRT2453501	hsa-miR-4733-3p	CLIP-seq
MIRT2453502	hsa-miR-4758-3p	CLIP-seq
MIRT2453496	hsa-miR-296-5p	CLIP-seq
MIRT2453497	hsa-miR-3184	CLIP-seq
MIRT2453498	hsa-miR-423-5p	CLIP-seq
MIRT2453499	hsa-miR-4523	CLIP-seq
MIRT2453500	hsa-miR-4685-5p	CLIP-seq
MIRT2453501	hsa-miR-4733-3p	CLIP-seq
MIRT2453502	hsa-miR-4758-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	TAS	8702478
GO:0001632	Function	Leukotriene B4 receptor activity	IBA	21873635
GO:0004974	Function	Leukotriene receptor activity	TAS	9177352
GO:0005886	Component	Plasma membrane	TAS
GO:0005887	Component	Integral component of plasma membrane	IBA	21873635
GO:0006936	Process	Muscle contraction	TAS	8702478
GO:0006954	Process	Inflammatory response	IBA	21873635
GO:0006955	Process	Immune response	TAS	9177352
GO:0007186	Process	G protein-coupled receptor signaling pathway	TAS
GO:0007200	Process	Phospholipase C-activating G protein-coupled receptor signaling pathway	TAS	8702478
GO:0007218	Process	Neuropeptide signaling pathway	IBA	21873635
GO:0008528	Function	G protein-coupled peptide receptor activity	IBA	21873635
GO:0045121	Component	Membrane raft	IEA
GO:0061737	Process	Leukotriene signaling pathway	IEA

MIM	HGNC	e!Ensembl
601531	6713	ENSG00000213903

Protein

UniProt ID

Q15722

Protein name

Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) (G-protein coupled receptor 16) (P2Y purinoceptor 7) (P2Y7)

Protein function

Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac mu

PDB

7K15 , 7VKT

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00001	7tm_1	35 → 285	7 transmembrane receptor (rhodopsin family)	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.

Sequence

MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN

Sequence length

352

Interactions

View interactions

	KEGG		Reactome
	Neuroactive ligand-receptor interaction		Leukotriene receptors G alpha (q) signalling events

LTB4R (leukotriene B4 receptor)