DCUN1D3 (defective in cullin neddylation 1 domain containing 3)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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123879 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Defective in cullin neddylation 1 domain containing 3 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DCUN1D3 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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44M2.4, DCNL3, SCCRO3 |
Chromosome
Chromosome number
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16 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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16p12.3 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q8IWE4 | ||||||||||
Protein name | DCN1-like protein 3 (DCNL3) (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3) (Squamous cell carcinoma-related oncogene 3) | ||||||||||
Protein function | Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and may play a role in the cell cycle progression by regulating the | ||||||||||
PDB | 4GBA | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Tends to be down-regulated in different type of cancers, including lung neuroendocrine carcinoma, thyroid Huerthle cell carcinoma and lung squamous cell carcinoma (PubMed:25349211). Mostly expressed in testis and brain (PubMed:26906416 | ||||||||||
Sequence |
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Sequence length | 304 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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