DCUN1D3 (defective in cullin neddylation 1 domain containing 3)
| Gene | |
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
123879 |
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Defective in cullin neddylation 1 domain containing 3 |
|
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
DCUN1D3 |
|
Synonyms (NCBI Gene)
Gene synonyms aliases
|
44M2.4, DCNL3, SCCRO3 |
|
Chromosome
Chromosome number
|
16 |
|
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
16p12.3 |
|
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
|||||||
| Protein | |||||||||||
| UniProt ID | Q8IWE4 | ||||||||||
| Protein name | DCN1-like protein 3 (DCNL3) (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3) (Squamous cell carcinoma-related oncogene 3) | ||||||||||
| Protein function | Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and may play a role in the cell cycle progression by regulating the | ||||||||||
| PDB | 4GBA | ||||||||||
| Family and domains |
Pfam
|
||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Tends to be down-regulated in different type of cancers, including lung neuroendocrine carcinoma, thyroid Huerthle cell carcinoma and lung squamous cell carcinoma (PubMed:25349211). Mostly expressed in testis and brain (PubMed:26906416 | ||||||||||
| Sequence |
|
||||||||||
| Sequence length | 304 | ||||||||||
| Interactions | View interactions | ||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||
|
|||||||