WHAMM (WASP homolog associated with actin, golgi membranes and microtubules)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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123720 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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WASP homolog associated with actin, golgi membranes and microtubules |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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WHAMM |
Synonyms (NCBI Gene)
Gene synonyms aliases
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WHAMM1, WHDC1 |
Chromosome
Chromosome number
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15 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q25.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a protein that plays a role in actin nucleation, Golgi membrane association and microtubule binding. The encoded protein is a nucleation-promoting factor that regulates the Actin-related protein 2/3 complex. The activated complex initiat |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q8TF30 | |||||||||||||||
Protein name | WASP homolog-associated protein with actin, membranes and microtubules (WAS protein homology region 2 domain-containing protein 1) (WH2 domain-containing protein 1) | |||||||||||||||
Protein function | Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes. Its activity in membrane tubulation requires F-actin and interaction with microtubules. Pro | |||||||||||||||
PDB | 5X1G | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed in brain, lung, heart, colon and kidney (at protein level). | |||||||||||||||
Sequence |
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Sequence length | 809 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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