WHAMM (WASP homolog associated with actin, golgi membranes and microtubules)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 123720 |
| Gene name | WASP homolog associated with actin, golgi membranes and microtubules |
| Gene symbol | WHAMM |
| Synonyms (NCBI Gene) |
WHAMM1WHDC1
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| Chromosome | 15 |
| Chromosome location | 15q25.2 |
| Summary | This gene encodes a protein that plays a role in actin nucleation, Golgi membrane association and microtubule binding. The encoded protein is a nucleation-promoting factor that regulates the Actin-related protein 2/3 complex. The activated complex initiat |
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miRNA
miRNA information provided by mirtarbase database.
492
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8TF30 | |||||||||||||||
| Protein name | WASP homolog-associated protein with actin, membranes and microtubules (WAS protein homology region 2 domain-containing protein 1) (WH2 domain-containing protein 1) | |||||||||||||||
| Protein function | Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes. Its activity in membrane tubulation requires F-actin and interaction with microtubules. Pro | |||||||||||||||
| PDB | 5X1G | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in brain, lung, heart, colon and kidney (at protein level). | |||||||||||||||
| Sequence |
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| Sequence length | 809 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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