CSNK1A1L (casein kinase 1 alpha 1 like)

Gene

• Entrez ID: 122011
• Gene name: Casein kinase 1 alpha 1 like
• Gene symbol: CSNK1A1L
• Synonyms (NCBI Gene): CK1
• Chromosome: 13
• Chromosome location: 13q13.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020882	hsa-miR-155-5p	Proteomics	18668040
MIRT735157	hsa-miR-576-3p	Western blotting	32765697
MIRT912143	hsa-miR-1915	CLIP-seq
MIRT912144	hsa-miR-3163	CLIP-seq
MIRT912145	hsa-miR-323b-5p	CLIP-seq
MIRT912146	hsa-miR-4282	CLIP-seq
MIRT912147	hsa-miR-4434	CLIP-seq
MIRT912148	hsa-miR-450b-5p	CLIP-seq
MIRT912149	hsa-miR-4516	CLIP-seq
MIRT912150	hsa-miR-4531	CLIP-seq
MIRT912151	hsa-miR-4534	CLIP-seq
MIRT912152	hsa-miR-4699-3p	CLIP-seq
MIRT912153	hsa-miR-4708-3p	CLIP-seq
MIRT912154	hsa-miR-518a-5p	CLIP-seq
MIRT912155	hsa-miR-527	CLIP-seq
MIRT912156	hsa-miR-584	CLIP-seq
MIRT1970383	hsa-miR-3975	CLIP-seq
MIRT1970384	hsa-miR-4275	CLIP-seq
MIRT1970385	hsa-miR-4797-5p	CLIP-seq
MIRT1970386	hsa-miR-513b	CLIP-seq
MIRT2206320	hsa-miR-3122	CLIP-seq
MIRT912145	hsa-miR-323b-5p	CLIP-seq
MIRT2206321	hsa-miR-371-5p	CLIP-seq
MIRT2206322	hsa-miR-371b-5p	CLIP-seq
MIRT2206323	hsa-miR-3913-5p	CLIP-seq
MIRT1970383	hsa-miR-3975	CLIP-seq
MIRT1970384	hsa-miR-4275	CLIP-seq
MIRT2206324	hsa-miR-450b-3p	CLIP-seq
MIRT2206325	hsa-miR-4652-3p	CLIP-seq
MIRT2206326	hsa-miR-4777-3p	CLIP-seq
MIRT1970385	hsa-miR-4797-5p	CLIP-seq
MIRT1970386	hsa-miR-513b	CLIP-seq
MIRT912156	hsa-miR-584	CLIP-seq
MIRT2206327	hsa-miR-769-3p	CLIP-seq
MIRT2206328	hsa-miR-889	CLIP-seq
MIRT2206329	hsa-miR-935	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0007165	Process	Signal transduction	IBA
GO:0016055	Process	Wnt signaling pathway	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0090090	Process	Negative regulation of canonical Wnt signaling pathway	IBA
GO:0106310	Function	Protein serine kinase activity	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8N752
• Protein name: Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)
• Protein function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00069	Pkinase	17 → 260	Protein kinase domain	Domain

• Sequence:

  MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYE
  SKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
  ISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKH
  LIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKK
  MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTM
  LKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN

• Sequence length: 337

Pathways

KEGG:

Wnt signaling pathway
Hedgehog signaling pathway
Alzheimer disease
Pathways of neurodegeneration - multiple diseases
Human papillomavirus infection
Breast cancer
Hepatocellular carcinoma
Gastric cancer

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