ABTB3 (ankyrin repeat and BTB domain containing 3)

Gene

• Entrez ID: 121551
• Gene name: Ankyrin repeat and BTB domain containing 3
• Gene symbol: ABTB3
• Synonyms (NCBI Gene): ABTB2B, BTBD11
• Chromosome: 12
• Chromosome location: 12q23.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT826252	hsa-miR-1254	CLIP-seq
MIRT826253	hsa-miR-1291	CLIP-seq
MIRT826254	hsa-miR-2054	CLIP-seq
MIRT826255	hsa-miR-3116	CLIP-seq
MIRT826256	hsa-miR-3612	CLIP-seq
MIRT826257	hsa-miR-374c	CLIP-seq
MIRT826258	hsa-miR-4254	CLIP-seq
MIRT826259	hsa-miR-4443	CLIP-seq
MIRT826260	hsa-miR-4539	CLIP-seq
MIRT826261	hsa-miR-650	CLIP-seq
MIRT826262	hsa-miR-655	CLIP-seq
MIRT826263	hsa-miR-661	CLIP-seq
MIRT1944330	hsa-miR-34a	CLIP-seq
MIRT1944331	hsa-miR-34c-5p	CLIP-seq
MIRT1944332	hsa-miR-3910	CLIP-seq
MIRT1944333	hsa-miR-4279	CLIP-seq
MIRT1944334	hsa-miR-449a	CLIP-seq
MIRT1944335	hsa-miR-449b	CLIP-seq
MIRT1944336	hsa-miR-4528	CLIP-seq
MIRT2182886	hsa-miR-1200	CLIP-seq
MIRT2182887	hsa-miR-1207-3p	CLIP-seq
MIRT2182888	hsa-miR-2682	CLIP-seq
MIRT2182889	hsa-miR-27a	CLIP-seq
MIRT2182890	hsa-miR-27b	CLIP-seq
MIRT2182891	hsa-miR-3140-5p	CLIP-seq
MIRT2182892	hsa-miR-3146	CLIP-seq
MIRT2182893	hsa-miR-3190	CLIP-seq
MIRT2182894	hsa-miR-3607-5p	CLIP-seq
MIRT1944332	hsa-miR-3910	CLIP-seq
MIRT2182895	hsa-miR-3921	CLIP-seq
MIRT2182896	hsa-miR-4269	CLIP-seq
MIRT2182897	hsa-miR-4464	CLIP-seq
MIRT2182898	hsa-miR-4491	CLIP-seq
MIRT2182899	hsa-miR-4493	CLIP-seq
MIRT2182900	hsa-miR-4496	CLIP-seq
MIRT2182901	hsa-miR-449c	CLIP-seq
MIRT2182902	hsa-miR-450b-5p	CLIP-seq
MIRT2182903	hsa-miR-4514	CLIP-seq
MIRT2182904	hsa-miR-4653-3p	CLIP-seq
MIRT2182905	hsa-miR-4653-5p	CLIP-seq
MIRT2182906	hsa-miR-4657	CLIP-seq
MIRT2182907	hsa-miR-4692	CLIP-seq
MIRT2182908	hsa-miR-4742-5p	CLIP-seq
MIRT2182909	hsa-miR-4748	CLIP-seq
MIRT2182910	hsa-miR-513a-5p	CLIP-seq
MIRT2182911	hsa-miR-518a-5p	CLIP-seq
MIRT2182912	hsa-miR-527	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0016021	Component	Integral component of membrane	IEA
GO:0046982	Function	Protein heterodimerization activity	IEA
GO:0060395	Process	SMAD protein signal transduction	IBA	21873635

Other IDs

• MIM: 621028
• HGNC: 23844
• e!Ensembl: ENSG00000151136

Protein

• UniProt ID: A6QL63
• Protein name: Ankyrin repeat- and BTB/POZ domain-containing protein 3 (BTB/POZ domain-containing protein 11)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12796	Ank_2	633 → 718	Ankyrin repeats (3 copies)	Repeat
  PF00651	BTB	914 → 1022	BTB/POZ domain	Domain

• Sequence:

  MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMH
  SRHNSFDTVNTALVEDSEGLDCAGQHCSRLLPDLDEVPWTLQELEALLLRSRDPRAGPAV
  PGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTA
  AALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTAC
  MESLFRDIYSRVVASGVPRSCSGPGSGSGSGPGPSSGPGAAPAADKEREAPGGGAASGGA
  CSAASSASGGSSCCAPPAAAAAAVPPAAAANHHHHHHHALHEAPKFTVETLEHTVNNDSE
  IWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRSNKPGELPMFSQSELRTIEQSLLAT
  RVGSIAELSDLVSRAMHHLQPLNAKHHGNGTPLHHKQGALYWEPEALYTLCYFMHCPQME
  WENPNVEPSKVNLQVERPFLVLPPLMEWIRVAVAHAGHRRSFSMDSDDVRQAARLLLPGV
  DCEPRQLRADDCFCASRKLDAVAIEAKFKQDLGFRMLNCGRTDLVKQAVSLLGPDGINTM
  SEQGMTPLMYACVRGDEAMVQMLLDAGADLNVEVVSTPHKYPSVHPETRHWTALTFAVLH
  GHIPVVQLLLDAGAKVEGSVEHGEENYSETPLQLAAAVGNFELVSLLLERGADPLIGTMY
  RNGISTTPQGDMNSFSQAAAHGHRNVFRKLLAQPEKEKSDILSLEEILAEGTDLAETAPP
  PLCASRNSKAKLRALREAMYHSAEHGYVDVTIDIRSIGVPWTLHTWLESLRIAFQQHRRP
  LIQCLLKEFKTIQEEEYTEELVTQGLPLMFEILKASKNEVISQQLCVIFTHCYGPYPIPK
  LTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTNDG
  TCIEIGYVKYSIFQLVMQYLYYGGPESLLIKNNEIMELLSAAKFFQLEALQRHCEIICAK
  SINTDNCVDIYNHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQLLYDKNGEGTGQDVL
  QDLQRTLAIRIQSIHLSSSKGSVV

• Sequence length: 1104

Associated diseases

Unknown
Disease term	Disease name	Evidence	References	Source
Asthma	Asthma		24406073	ClinVar
Chronic obstructive pulmonary disease	Chronic Obstructive Airway Disease		26503814	ClinVar
Coronary artery disease	Coronary artery disease			GWAS
Metabolic Syndrome	Metabolic Syndrome			GWAS
Tremor	Tremor			GWAS
Myocardial Infarction	Myocardial Infarction			GWAS
Eosinophilia	Eosinophilia			GWAS