Gene Gene information from NCBI Gene database.
Entrez ID 120526
Gene name DnaJ heat shock protein family (Hsp40) member C24
Gene symbol DNAJC24
Synonyms (NCBI Gene)
DPH4JJJ3ZCSL3
Chromosome 11
Chromosome location 11p13
Summary Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of
miRNA miRNA information provided by mirtarbase database.
619
miRTarBase ID miRNA Experiments Reference
MIRT572135 hsa-miR-490-3p PAR-CLIP 20371350
MIRT572134 hsa-miR-619-3p PAR-CLIP 20371350
MIRT572133 hsa-miR-4716-3p PAR-CLIP 20371350
MIRT572132 hsa-miR-6794-5p PAR-CLIP 20371350
MIRT572131 hsa-miR-6744-5p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
GO ID Ontology Definition Evidence Reference
GO:0001671 Function ATPase activator activity IBA
GO:0001671 Function ATPase activator activity IDA 22367199
GO:0005737 Component Cytoplasm IEA
GO:0005856 Component Cytoskeleton IEA
GO:0006457 Process Protein folding TAS 22367199
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611072 26979 ENSG00000170946
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6P3W2
Protein name DnaJ homolog subfamily C member 24 (CSL-type zinc finger-containing protein 3) (Diphthamide biosynthesis protein 4)
Protein function Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translation
PDB 2L6L
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00226 DnaJ 11 79 DnaJ domain Domain
PF05207 zf-CSL 95 148 CSL zinc finger Domain
Sequence
Sequence length 149
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Synthesis of diphthamide-EEF2