DNAJC24 (DnaJ heat shock protein family (Hsp40) member C24)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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120526 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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DnaJ heat shock protein family (Hsp40) member C24 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DNAJC24 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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DPH4, JJJ3, ZCSL3 |
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Chromosome
Chromosome number
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11 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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11p13 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q6P3W2 | |||||||||||||||
| Protein name | DnaJ homolog subfamily C member 24 (CSL-type zinc finger-containing protein 3) (Diphthamide biosynthesis protein 4) | |||||||||||||||
| Protein function | Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translation | |||||||||||||||
| PDB | 2L6L | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 149 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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