Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	119587
Gene name	Carboxypeptidase X, M14 family member 2
Gene symbol	CPXM2
Synonyms (NCBI Gene)	CPX2UNQ676
Chromosome	10
Chromosome location	10q26.13

104

Show/Hide all (104)

miRTarBase ID	miRNA	Experiments	Reference
MIRT650450	hsa-miR-6819-3p	HITS-CLIP	23824327
MIRT650449	hsa-miR-6877-3p	HITS-CLIP	23824327
MIRT650448	hsa-miR-3183	HITS-CLIP	23824327
MIRT650447	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT650446	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT650445	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT650444	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT650443	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT650442	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT650440	hsa-miR-4539	HITS-CLIP	23824327
MIRT650441	hsa-miR-4695-3p	HITS-CLIP	23824327
MIRT650439	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT650438	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT650437	hsa-miR-6751-3p	HITS-CLIP	23824327
MIRT650450	hsa-miR-6819-3p	HITS-CLIP	23824327
MIRT650449	hsa-miR-6877-3p	HITS-CLIP	23824327
MIRT650448	hsa-miR-3183	HITS-CLIP	23824327
MIRT650447	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT650446	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT650445	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT650444	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT650443	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT650442	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT650440	hsa-miR-4539	HITS-CLIP	23824327
MIRT650441	hsa-miR-4695-3p	HITS-CLIP	23824327
MIRT650439	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT650438	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT650437	hsa-miR-6751-3p	HITS-CLIP	23824327
MIRT907816	hsa-miR-2117	CLIP-seq
MIRT907817	hsa-miR-3133	CLIP-seq
MIRT907818	hsa-miR-4768-5p	CLIP-seq
MIRT907819	hsa-miR-483-3p	CLIP-seq
MIRT1969111	hsa-miR-1915	CLIP-seq
MIRT1969112	hsa-miR-4726-3p	CLIP-seq
MIRT2205107	hsa-miR-1273d	CLIP-seq
MIRT2205108	hsa-miR-3663-3p	CLIP-seq
MIRT2436453	hsa-miR-29a	CLIP-seq
MIRT2436454	hsa-miR-29b	CLIP-seq
MIRT2436455	hsa-miR-29c	CLIP-seq
MIRT2436456	hsa-miR-4271	CLIP-seq
MIRT2436457	hsa-miR-4725-3p	CLIP-seq
MIRT2436458	hsa-miR-500a	CLIP-seq
MIRT2436459	hsa-miR-501-5p	CLIP-seq
MIRT2508434	hsa-miR-1237	CLIP-seq
MIRT2508435	hsa-miR-1243	CLIP-seq
MIRT2508436	hsa-miR-1248	CLIP-seq
MIRT1969111	hsa-miR-1915	CLIP-seq
MIRT2508437	hsa-miR-214	CLIP-seq
MIRT2436453	hsa-miR-29a	CLIP-seq
MIRT2436454	hsa-miR-29b	CLIP-seq
MIRT2436455	hsa-miR-29c	CLIP-seq
MIRT2508438	hsa-miR-3155	CLIP-seq
MIRT2508439	hsa-miR-3155b	CLIP-seq
MIRT2508440	hsa-miR-3619-5p	CLIP-seq
MIRT2508441	hsa-miR-3920	CLIP-seq
MIRT2508442	hsa-miR-3921	CLIP-seq
MIRT2436456	hsa-miR-4271	CLIP-seq
MIRT2508443	hsa-miR-4279	CLIP-seq
MIRT2508444	hsa-miR-4291	CLIP-seq
MIRT2508445	hsa-miR-4438	CLIP-seq
MIRT2508446	hsa-miR-4653-5p	CLIP-seq
MIRT2508447	hsa-miR-4667-3p	CLIP-seq
MIRT2436457	hsa-miR-4725-3p	CLIP-seq
MIRT1969112	hsa-miR-4726-3p	CLIP-seq
MIRT907818	hsa-miR-4768-5p	CLIP-seq
MIRT2508448	hsa-miR-484	CLIP-seq
MIRT2508449	hsa-miR-761	CLIP-seq
MIRT2508450	hsa-miR-922	CLIP-seq
MIRT2508451	hsa-miR-942	CLIP-seq
MIRT2508434	hsa-miR-1237	CLIP-seq
MIRT2508435	hsa-miR-1243	CLIP-seq
MIRT2508436	hsa-miR-1248	CLIP-seq
MIRT2678563	hsa-miR-1275	CLIP-seq
MIRT2678564	hsa-miR-149	CLIP-seq
MIRT2678565	hsa-miR-2110	CLIP-seq
MIRT2508437	hsa-miR-214	CLIP-seq
MIRT2678566	hsa-miR-2467-5p	CLIP-seq
MIRT2436453	hsa-miR-29a	CLIP-seq
MIRT2436454	hsa-miR-29b	CLIP-seq
MIRT2436455	hsa-miR-29c	CLIP-seq
MIRT2678567	hsa-miR-3064-5p	CLIP-seq
MIRT2678568	hsa-miR-3162-3p	CLIP-seq
MIRT2508440	hsa-miR-3619-5p	CLIP-seq
MIRT2678569	hsa-miR-3654	CLIP-seq
MIRT2678570	hsa-miR-4260	CLIP-seq
MIRT2436456	hsa-miR-4271	CLIP-seq
MIRT2678571	hsa-miR-4287	CLIP-seq
MIRT2508444	hsa-miR-4291	CLIP-seq
MIRT2678572	hsa-miR-4469	CLIP-seq
MIRT2678573	hsa-miR-4665-5p	CLIP-seq
MIRT2508447	hsa-miR-4667-3p	CLIP-seq
MIRT2678574	hsa-miR-4667-5p	CLIP-seq
MIRT2678575	hsa-miR-4685-3p	CLIP-seq
MIRT2678576	hsa-miR-4685-5p	CLIP-seq
MIRT2678577	hsa-miR-4700-5p	CLIP-seq
MIRT2436457	hsa-miR-4725-3p	CLIP-seq
MIRT2678578	hsa-miR-4794	CLIP-seq
MIRT2436458	hsa-miR-500a	CLIP-seq
MIRT2436459	hsa-miR-501-5p	CLIP-seq
MIRT2678579	hsa-miR-619	CLIP-seq
MIRT2678580	hsa-miR-760	CLIP-seq
MIRT2508449	hsa-miR-761	CLIP-seq
MIRT2678581	hsa-miR-887	CLIP-seq
MIRT2508450	hsa-miR-922	CLIP-seq

Show/Hide all (4)

GO ID	Ontology	Definition	Evidence
GO:0004181	Function	Metallocarboxypeptidase activity	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0006508	Process	Proteolysis	IEA
GO:0008270	Function	Zinc ion binding	IEA

MIM	HGNC	e!Ensembl
617348	26977	ENSG00000121898

Q8N436

Protein name

Inactive carboxypeptidase-like protein X2

Protein function

May be involved in cell-cell interactions.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00754	F5_F8_type_C	150 → 290	F5/8 type C domain	Domain
PF00246	Peptidase_M14	324 → 632	Zinc carboxypeptidase	Domain
PF13620	CarboxypepD_reg	643 → 719		Domain

Sequence

MSRPGTATPALALVLLAVTLAGVGAQGAALEDPDYYGQEIWSREPYYARPEPELETFSPP
LPAGPGEEWERRPQEPRPPKRATKPKKAPKREKSAPEPPPPGKHSNKKVMRTKSSEKAAN
DDHSVRVAREDVRESCPPLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFY
DGAWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVK
NGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNN
YYHRRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISD
HPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLP
SLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHY
IAIPEWFLSENATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHT
PTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYL
HTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAI
ISVEGINHDIRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSK
TNMARIREIMEKFGKQPVSLPARRLKLRGQKRRQRG

Sequence length

756

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (11)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast ductal adenocarcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CENTRAL NERVOUS SYSTEM CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EBV-positive nodal T- and NK-cell lymphoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOBLASTOMA MULTIFORME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SUBSTANCE ABUSE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ULCERATIVE COLITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (9)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Alzheimer Disease	Associate	27805002	★★★★★ ★☆☆☆☆ Found in Text Mining only
Bone Diseases Developmental	Associate	31364750	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Associate	31364750, 31651348	★★★★★ ★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Associate	31651348	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Stimulate	31651348	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	31364750, 31651348	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Associate	31651348	★★★★★ ★☆☆☆☆ Found in Text Mining only
Personality Disorders	Associate	30217166	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stimulate	31364750	★★★★★ ★☆☆☆☆ Found in Text Mining only

CPXM2 (carboxypeptidase X, M14 family member 2)