ANKRD22 (ankyrin repeat domain 22)

Gene

• Entrez ID: 118932
• Gene name: Ankyrin repeat domain 22
• Gene symbol: ANKRD22
• Synonyms (NCBI Gene): -
• Chromosome: 10
• Chromosome location: 10q23.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019025	hsa-miR-335-5p	Microarray	18185580
MIRT783137	hsa-miR-101	CLIP-seq
MIRT783138	hsa-miR-1184	CLIP-seq
MIRT783139	hsa-miR-1205	CLIP-seq
MIRT783140	hsa-miR-1246	CLIP-seq
MIRT783141	hsa-miR-1255a	CLIP-seq
MIRT783142	hsa-miR-1255b	CLIP-seq
MIRT783143	hsa-miR-1272	CLIP-seq
MIRT783144	hsa-miR-129-5p	CLIP-seq
MIRT783145	hsa-miR-1305	CLIP-seq
MIRT783146	hsa-miR-135a	CLIP-seq
MIRT783147	hsa-miR-135b	CLIP-seq
MIRT783148	hsa-miR-144	CLIP-seq
MIRT783149	hsa-miR-147	CLIP-seq
MIRT783150	hsa-miR-153	CLIP-seq
MIRT783151	hsa-miR-2355-3p	CLIP-seq
MIRT783152	hsa-miR-30a	CLIP-seq
MIRT783153	hsa-miR-30b	CLIP-seq
MIRT783154	hsa-miR-30c	CLIP-seq
MIRT783155	hsa-miR-30d	CLIP-seq
MIRT783156	hsa-miR-30e	CLIP-seq
MIRT783157	hsa-miR-3119	CLIP-seq
MIRT783158	hsa-miR-3120-5p	CLIP-seq
MIRT783159	hsa-miR-3158-5p	CLIP-seq
MIRT783160	hsa-miR-3163	CLIP-seq
MIRT783161	hsa-miR-3192	CLIP-seq
MIRT783162	hsa-miR-346	CLIP-seq
MIRT783163	hsa-miR-3614-5p	CLIP-seq
MIRT783164	hsa-miR-3622a-3p	CLIP-seq
MIRT783165	hsa-miR-3622b-3p	CLIP-seq
MIRT783166	hsa-miR-3689a-3p	CLIP-seq
MIRT783167	hsa-miR-3689c	CLIP-seq
MIRT783168	hsa-miR-3911	CLIP-seq
MIRT783169	hsa-miR-3928	CLIP-seq
MIRT783170	hsa-miR-409-3p	CLIP-seq
MIRT783171	hsa-miR-4288	CLIP-seq
MIRT783172	hsa-miR-4302	CLIP-seq
MIRT783173	hsa-miR-4421	CLIP-seq
MIRT783174	hsa-miR-4426	CLIP-seq
MIRT783175	hsa-miR-448	CLIP-seq
MIRT783176	hsa-miR-4492	CLIP-seq
MIRT783177	hsa-miR-4498	CLIP-seq
MIRT783178	hsa-miR-4505	CLIP-seq
MIRT783179	hsa-miR-4646-3p	CLIP-seq
MIRT783180	hsa-miR-4647	CLIP-seq
MIRT783181	hsa-miR-4662b	CLIP-seq
MIRT783182	hsa-miR-4698	CLIP-seq
MIRT783183	hsa-miR-4704-3p	CLIP-seq
MIRT783184	hsa-miR-4728-5p	CLIP-seq
MIRT783185	hsa-miR-4738-3p	CLIP-seq
MIRT783186	hsa-miR-485-5p	CLIP-seq
MIRT783187	hsa-miR-544	CLIP-seq
MIRT783188	hsa-miR-581	CLIP-seq
MIRT783189	hsa-miR-582-5p	CLIP-seq
MIRT783190	hsa-miR-586	CLIP-seq
MIRT783191	hsa-miR-607	CLIP-seq
MIRT783192	hsa-miR-622	CLIP-seq
MIRT783193	hsa-miR-629	CLIP-seq
MIRT783194	hsa-miR-632	CLIP-seq
MIRT783195	hsa-miR-644	CLIP-seq
MIRT783196	hsa-miR-762	CLIP-seq
MIRT783138	hsa-miR-1184	CLIP-seq
MIRT783139	hsa-miR-1205	CLIP-seq
MIRT783144	hsa-miR-129-5p	CLIP-seq
MIRT1931061	hsa-miR-1301	CLIP-seq
MIRT783149	hsa-miR-147	CLIP-seq
MIRT1931062	hsa-miR-204	CLIP-seq
MIRT1931063	hsa-miR-211	CLIP-seq
MIRT783158	hsa-miR-3120-5p	CLIP-seq
MIRT1931064	hsa-miR-3154	CLIP-seq
MIRT783159	hsa-miR-3158-5p	CLIP-seq
MIRT783162	hsa-miR-346	CLIP-seq
MIRT1931065	hsa-miR-3591-3p	CLIP-seq
MIRT1931066	hsa-miR-3591-5p	CLIP-seq
MIRT1931067	hsa-miR-4255	CLIP-seq
MIRT783171	hsa-miR-4288	CLIP-seq
MIRT783173	hsa-miR-4421	CLIP-seq
MIRT1931068	hsa-miR-4446-5p	CLIP-seq
MIRT1931069	hsa-miR-4501	CLIP-seq
MIRT1931070	hsa-miR-4660	CLIP-seq
MIRT1931071	hsa-miR-4755-5p	CLIP-seq
MIRT1931072	hsa-miR-5047	CLIP-seq
MIRT1931073	hsa-miR-548l	CLIP-seq
MIRT1931074	hsa-miR-548n	CLIP-seq
MIRT1931075	hsa-miR-592	CLIP-seq
MIRT1931076	hsa-miR-597	CLIP-seq
MIRT1931077	hsa-miR-599	CLIP-seq
MIRT1931078	hsa-miR-623	CLIP-seq
MIRT783194	hsa-miR-632	CLIP-seq
MIRT2171667	hsa-miR-106a	CLIP-seq
MIRT2171668	hsa-miR-106b	CLIP-seq
MIRT2171669	hsa-miR-1224-3p	CLIP-seq
MIRT2171670	hsa-miR-1245	CLIP-seq
MIRT2171671	hsa-miR-1260	CLIP-seq
MIRT2171672	hsa-miR-1260b	CLIP-seq
MIRT2171673	hsa-miR-1279	CLIP-seq
MIRT2171674	hsa-miR-1280	CLIP-seq
MIRT2171675	hsa-miR-1297	CLIP-seq
MIRT2171676	hsa-miR-150	CLIP-seq
MIRT2171677	hsa-miR-17	CLIP-seq
MIRT2171678	hsa-miR-203	CLIP-seq
MIRT2171679	hsa-miR-20a	CLIP-seq
MIRT2171680	hsa-miR-20b	CLIP-seq
MIRT2171681	hsa-miR-26a	CLIP-seq
MIRT2171682	hsa-miR-26b	CLIP-seq
MIRT2171683	hsa-miR-3117-5p	CLIP-seq
MIRT2171684	hsa-miR-3136-5p	CLIP-seq
MIRT2171685	hsa-miR-3609	CLIP-seq
MIRT2171686	hsa-miR-4282	CLIP-seq
MIRT2171687	hsa-miR-4438	CLIP-seq
MIRT2171688	hsa-miR-4439	CLIP-seq
MIRT2171689	hsa-miR-4465	CLIP-seq
MIRT2171690	hsa-miR-4682	CLIP-seq
MIRT2171691	hsa-miR-4796-3p	CLIP-seq
MIRT2171692	hsa-miR-5095	CLIP-seq
MIRT2171693	hsa-miR-519d	CLIP-seq
MIRT2171694	hsa-miR-532-3p	CLIP-seq
MIRT2171695	hsa-miR-548ah	CLIP-seq
MIRT2171696	hsa-miR-562	CLIP-seq
MIRT2171697	hsa-miR-93	CLIP-seq
MIRT2443658	hsa-miR-1182	CLIP-seq
MIRT2443659	hsa-miR-146b-3p	CLIP-seq
MIRT2443660	hsa-miR-3064-5p	CLIP-seq
MIRT2443661	hsa-miR-3157-3p	CLIP-seq
MIRT2443662	hsa-miR-3173-5p	CLIP-seq
MIRT2443663	hsa-miR-4423-5p	CLIP-seq
MIRT2443664	hsa-miR-720	CLIP-seq
MIRT2443665	hsa-miR-874	CLIP-seq
MIRT783143	hsa-miR-1272	CLIP-seq
MIRT1931062	hsa-miR-204	CLIP-seq
MIRT1931063	hsa-miR-211	CLIP-seq
MIRT2171684	hsa-miR-3136-5p	CLIP-seq
MIRT1931064	hsa-miR-3154	CLIP-seq
MIRT2474739	hsa-miR-3159	CLIP-seq
MIRT2474740	hsa-miR-345	CLIP-seq
MIRT1931066	hsa-miR-3591-5p	CLIP-seq
MIRT2474741	hsa-miR-3616-5p	CLIP-seq
MIRT2474742	hsa-miR-3647-5p	CLIP-seq
MIRT1931067	hsa-miR-4255	CLIP-seq
MIRT2474743	hsa-miR-4256	CLIP-seq
MIRT2474744	hsa-miR-4328	CLIP-seq
MIRT2171688	hsa-miR-4439	CLIP-seq
MIRT1931068	hsa-miR-4446-5p	CLIP-seq
MIRT2474745	hsa-miR-4513	CLIP-seq
MIRT1931071	hsa-miR-4755-5p	CLIP-seq
MIRT2474746	hsa-miR-4762-3p	CLIP-seq
MIRT2474747	hsa-miR-4795-5p	CLIP-seq
MIRT2474748	hsa-miR-494	CLIP-seq
MIRT2474749	hsa-miR-573	CLIP-seq
MIRT1931078	hsa-miR-623	CLIP-seq
MIRT2171684	hsa-miR-3136-5p	CLIP-seq
MIRT2474740	hsa-miR-345	CLIP-seq
MIRT2474741	hsa-miR-3616-5p	CLIP-seq
MIRT2474742	hsa-miR-3647-5p	CLIP-seq
MIRT2474743	hsa-miR-4256	CLIP-seq
MIRT2474744	hsa-miR-4328	CLIP-seq
MIRT2171688	hsa-miR-4439	CLIP-seq
MIRT2474745	hsa-miR-4513	CLIP-seq
MIRT2474746	hsa-miR-4762-3p	CLIP-seq
MIRT2474747	hsa-miR-4795-5p	CLIP-seq
MIRT2474748	hsa-miR-494	CLIP-seq
MIRT2474749	hsa-miR-573	CLIP-seq

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q5VYY1
• Protein name: Ankyrin repeat domain-containing protein 22
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12796	Ank_2	9 → 95	Ankyrin repeats (3 copies)	Repeat
  PF13857	Ank_5	121 → 175		Repeat

• Sequence:

  MGILYSEPICQAAYQNDFGQVWRWVKEDSSYANVQDGFNGDTPLICACRRGHVRIVSFLL
  RRNANVNLKNQKERTCLHYAVKKKFTFIDYLLIILLMPVLLIGYFLMVSKTKQNEALVRM
  LLDAGVEVNATDCYGCTALHYACEMKNQSLIPLLLEARADPTIKNKHGESSLDIARRLKF
  SQIELMLRKAL

• Sequence length: 191

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
COLORECTAL MUCINOUS ADENOCARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LATE-ONSET ALZHEIMER'S DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SMALL VESSEL STROKE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Breast Neoplasms	Associate	32651974	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Inhibit	35697697	★☆☆☆☆ Found in Text Mining only
Carcinoma Intraductal Noninfiltrating	Inhibit	35697697	★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Stimulate	34337010	★☆☆☆☆ Found in Text Mining only
Neoplasms	Stimulate	32651974	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Associate	36906533, 39487387	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Stimulate	40225855	★☆☆☆☆ Found in Text Mining only
Tuberculosis Meningeal	Associate	38288122	★☆☆☆☆ Found in Text Mining only