Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	116159
Gene name	Cysteine and tyrosine rich 1
Gene symbol	CYYR1
Synonyms (NCBI Gene)	C21orf95
Chromosome	21
Chromosome location	21q21.3

128

Show/Hide all (128)

miRTarBase ID	miRNA	Experiments	Reference
MIRT019006	hsa-miR-335-5p	Microarray	18185580
MIRT711132	hsa-miR-5692a	HITS-CLIP	19536157
MIRT711131	hsa-miR-3156-5p	HITS-CLIP	19536157
MIRT711130	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT711129	hsa-miR-1267	HITS-CLIP	19536157
MIRT711128	hsa-miR-367-5p	HITS-CLIP	19536157
MIRT711127	hsa-miR-4743-3p	HITS-CLIP	19536157
MIRT711126	hsa-miR-4652-3p	HITS-CLIP	19536157
MIRT711132	hsa-miR-5692a	HITS-CLIP	19536157
MIRT711131	hsa-miR-3156-5p	HITS-CLIP	19536157
MIRT711130	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT711129	hsa-miR-1267	HITS-CLIP	19536157
MIRT711128	hsa-miR-367-5p	HITS-CLIP	19536157
MIRT711127	hsa-miR-4743-3p	HITS-CLIP	19536157
MIRT711126	hsa-miR-4652-3p	HITS-CLIP	19536157
MIRT711132	hsa-miR-5692a	HITS-CLIP	19536157
MIRT711131	hsa-miR-3156-5p	HITS-CLIP	19536157
MIRT711130	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT711129	hsa-miR-1267	HITS-CLIP	19536157
MIRT711128	hsa-miR-367-5p	HITS-CLIP	19536157
MIRT711127	hsa-miR-4743-3p	HITS-CLIP	19536157
MIRT711126	hsa-miR-4652-3p	HITS-CLIP	19536157
MIRT711132	hsa-miR-5692a	HITS-CLIP	19536157
MIRT711131	hsa-miR-3156-5p	HITS-CLIP	19536157
MIRT711130	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT711129	hsa-miR-1267	HITS-CLIP	19536157
MIRT711128	hsa-miR-367-5p	HITS-CLIP	19536157
MIRT711127	hsa-miR-4743-3p	HITS-CLIP	19536157
MIRT711126	hsa-miR-4652-3p	HITS-CLIP	19536157
MIRT711125	hsa-miR-7849-3p	HITS-CLIP	19536157
MIRT711124	hsa-miR-4666a-3p	HITS-CLIP	19536157
MIRT711122	hsa-miR-4286	HITS-CLIP	19536157
MIRT711123	hsa-miR-4713-5p	HITS-CLIP	19536157
MIRT711121	hsa-miR-6867-3p	HITS-CLIP	19536157
MIRT711120	hsa-miR-629-3p	HITS-CLIP	19536157
MIRT711132	hsa-miR-5692a	HITS-CLIP	19536157
MIRT711131	hsa-miR-3156-5p	HITS-CLIP	19536157
MIRT711130	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT711129	hsa-miR-1267	HITS-CLIP	19536157
MIRT711128	hsa-miR-367-5p	HITS-CLIP	19536157
MIRT711127	hsa-miR-4743-3p	HITS-CLIP	19536157
MIRT711126	hsa-miR-4652-3p	HITS-CLIP	19536157
MIRT711132	hsa-miR-5692a	HITS-CLIP	19536157
MIRT711131	hsa-miR-3156-5p	HITS-CLIP	19536157
MIRT711130	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT711129	hsa-miR-1267	HITS-CLIP	19536157
MIRT711128	hsa-miR-367-5p	HITS-CLIP	19536157
MIRT711127	hsa-miR-4743-3p	HITS-CLIP	19536157
MIRT711126	hsa-miR-4652-3p	HITS-CLIP	19536157
MIRT711132	hsa-miR-5692a	HITS-CLIP	19536157
MIRT711131	hsa-miR-3156-5p	HITS-CLIP	19536157
MIRT711130	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT711129	hsa-miR-1267	HITS-CLIP	19536157
MIRT711128	hsa-miR-367-5p	HITS-CLIP	19536157
MIRT711127	hsa-miR-4743-3p	HITS-CLIP	19536157
MIRT711126	hsa-miR-4652-3p	HITS-CLIP	19536157
MIRT711132	hsa-miR-5692a	HITS-CLIP	19536157
MIRT711131	hsa-miR-3156-5p	HITS-CLIP	19536157
MIRT711130	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT711129	hsa-miR-1267	HITS-CLIP	19536157
MIRT711128	hsa-miR-367-5p	HITS-CLIP	19536157
MIRT711127	hsa-miR-4743-3p	HITS-CLIP	19536157
MIRT711126	hsa-miR-4652-3p	HITS-CLIP	19536157
MIRT711125	hsa-miR-7849-3p	HITS-CLIP	19536157
MIRT711124	hsa-miR-4666a-3p	HITS-CLIP	19536157
MIRT711122	hsa-miR-4286	HITS-CLIP	19536157
MIRT711123	hsa-miR-4713-5p	HITS-CLIP	19536157
MIRT711121	hsa-miR-6867-3p	HITS-CLIP	19536157
MIRT711120	hsa-miR-629-3p	HITS-CLIP	19536157
MIRT922355	hsa-miR-1272	CLIP-seq
MIRT922356	hsa-miR-1273d	CLIP-seq
MIRT922357	hsa-miR-128	CLIP-seq
MIRT922358	hsa-miR-3122	CLIP-seq
MIRT922359	hsa-miR-3167	CLIP-seq
MIRT922360	hsa-miR-3180-5p	CLIP-seq
MIRT922361	hsa-miR-330-3p	CLIP-seq
MIRT922362	hsa-miR-335	CLIP-seq
MIRT922363	hsa-miR-346	CLIP-seq
MIRT922364	hsa-miR-3616-5p	CLIP-seq
MIRT922365	hsa-miR-3622a-5p	CLIP-seq
MIRT922366	hsa-miR-3647-5p	CLIP-seq
MIRT922367	hsa-miR-3682-3p	CLIP-seq
MIRT922368	hsa-miR-3913-5p	CLIP-seq
MIRT922369	hsa-miR-4288	CLIP-seq
MIRT922370	hsa-miR-4420	CLIP-seq
MIRT922371	hsa-miR-4423-3p	CLIP-seq
MIRT922372	hsa-miR-450b-3p	CLIP-seq
MIRT922373	hsa-miR-4662a-5p	CLIP-seq
MIRT922374	hsa-miR-4680-3p	CLIP-seq
MIRT922375	hsa-miR-4684-5p	CLIP-seq
MIRT922376	hsa-miR-4719	CLIP-seq
MIRT922377	hsa-miR-4778-3p	CLIP-seq
MIRT922378	hsa-miR-4795-5p	CLIP-seq
MIRT922379	hsa-miR-513b	CLIP-seq
MIRT922380	hsa-miR-573	CLIP-seq
MIRT922381	hsa-miR-593	CLIP-seq
MIRT922382	hsa-miR-632	CLIP-seq
MIRT922383	hsa-miR-665	CLIP-seq
MIRT922384	hsa-miR-769-3p	CLIP-seq
MIRT922385	hsa-miR-876-5p	CLIP-seq
MIRT922386	hsa-miR-890	CLIP-seq
MIRT922387	hsa-miR-924	CLIP-seq
MIRT1973201	hsa-miR-1323	CLIP-seq
MIRT1973202	hsa-miR-3157-5p	CLIP-seq
MIRT1973203	hsa-miR-548o	CLIP-seq
MIRT922386	hsa-miR-890	CLIP-seq
MIRT922357	hsa-miR-128	CLIP-seq
MIRT2208884	hsa-miR-4266	CLIP-seq
MIRT922373	hsa-miR-4662a-5p	CLIP-seq
MIRT2208885	hsa-miR-4666-3p	CLIP-seq
MIRT2208886	hsa-miR-4695-5p	CLIP-seq
MIRT2208887	hsa-miR-4779	CLIP-seq
MIRT2208888	hsa-miR-545	CLIP-seq
MIRT2208889	hsa-miR-548p	CLIP-seq
MIRT922387	hsa-miR-924	CLIP-seq
MIRT2428085	hsa-miR-3145-3p	CLIP-seq
MIRT2428086	hsa-miR-4503	CLIP-seq
MIRT2428087	hsa-miR-4760-5p	CLIP-seq
MIRT2447977	hsa-miR-150	CLIP-seq
MIRT2447978	hsa-miR-532-3p	CLIP-seq
MIRT2512649	hsa-miR-3613-5p	CLIP-seq
MIRT2512650	hsa-miR-3690	CLIP-seq
MIRT2512651	hsa-miR-4254	CLIP-seq
MIRT2512652	hsa-miR-4638-3p	CLIP-seq
MIRT2512653	hsa-miR-483-3p	CLIP-seq
MIRT2512654	hsa-miR-630	CLIP-seq
MIRT2679010	hsa-miR-340	CLIP-seq
MIRT2679011	hsa-miR-494	CLIP-seq

Show/Hide all (3)

GO ID	Ontology	Definition	Evidence
GO:0003674	Function	Molecular_function	ND
GO:0008150	Process	Biological_process	ND
GO:0016020	Component	Membrane	IEA

MIM	HGNC	e!Ensembl
616020	16274	ENSG00000166265

Q96J86

Protein name

Cysteine and tyrosine-rich protein 1 (Proline-rich domain-containing protein)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10873	CYYR1	7 → 154	Cysteine and tyrosine-rich protein 1	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:12036297, ECO:0000269|PubMed:17442112}.

Sequence

MDAPRLPVRPGVLLPKLVLLFVYADDCLAQCGKDCKSYCCDGTTPYCCSYYAYIGNILSG
TAIAGIVFGIVFIMGVIAGIAICICMCMKNHRATRVGILRTTHINTVSSYPGPPPYGHDH
EMEYCADLPPPYSPTPQGPAQRSPPPPYPGNARK

Sequence length

154

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LATE-ONSET ALZHEIMER'S DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Bronchopulmonary Dysplasia	Associate	38277517	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Associate	26646589	★★★★★ ★☆☆☆☆ Found in Text Mining only

CYYR1 (cysteine and tyrosine rich 1)