BATF2 (basic leucine zipper ATF-like transcription factor 2)

Gene

• Entrez ID: 116071
• Gene name: Basic leucine zipper ATF-like transcription factor 2
• Gene symbol: BATF2
• Synonyms (NCBI Gene): SARI
• Chromosome: 11
• Chromosome location: 11q13.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017734	hsa-miR-335-5p	Microarray	18185580
MIRT019820	hsa-miR-375	Microarray	20215506
MIRT023328	hsa-miR-122-5p	Microarray	17612493
MIRT736956	hsa-miR-765	Luciferase reporter assay, Western blotting, qRT-PCR, Flow cytometry	32166887
MIRT755973	hsa-miR-5189-3p	Luciferase reporter assay, Western blotting, qRT-PCR	35246006
MIRT816062	hsa-miR-122	CLIP-seq
MIRT816063	hsa-miR-1231	CLIP-seq
MIRT816064	hsa-miR-1288	CLIP-seq
MIRT816065	hsa-miR-1827	CLIP-seq
MIRT816066	hsa-miR-217	CLIP-seq
MIRT816067	hsa-miR-2909	CLIP-seq
MIRT816068	hsa-miR-3119	CLIP-seq
MIRT816069	hsa-miR-3150a-3p	CLIP-seq
MIRT816070	hsa-miR-3170	CLIP-seq
MIRT816071	hsa-miR-3175	CLIP-seq
MIRT816072	hsa-miR-3192	CLIP-seq
MIRT816073	hsa-miR-3199	CLIP-seq
MIRT816074	hsa-miR-34a	CLIP-seq
MIRT816075	hsa-miR-34c-5p	CLIP-seq
MIRT816076	hsa-miR-3612	CLIP-seq
MIRT816077	hsa-miR-4255	CLIP-seq
MIRT816078	hsa-miR-4278	CLIP-seq
MIRT816079	hsa-miR-4288	CLIP-seq
MIRT816080	hsa-miR-4314	CLIP-seq
MIRT816081	hsa-miR-449a	CLIP-seq
MIRT816082	hsa-miR-449b	CLIP-seq
MIRT816083	hsa-miR-4637	CLIP-seq
MIRT816084	hsa-miR-4646-5p	CLIP-seq
MIRT816085	hsa-miR-4688	CLIP-seq
MIRT816086	hsa-miR-4729	CLIP-seq
MIRT816087	hsa-miR-4765	CLIP-seq
MIRT816088	hsa-miR-4766-5p	CLIP-seq
MIRT816089	hsa-miR-4796-3p	CLIP-seq
MIRT816090	hsa-miR-4803	CLIP-seq
MIRT816091	hsa-miR-486-3p	CLIP-seq
MIRT816092	hsa-miR-491-5p	CLIP-seq
MIRT816093	hsa-miR-548t	CLIP-seq
MIRT816094	hsa-miR-579	CLIP-seq
MIRT816095	hsa-miR-632	CLIP-seq
MIRT816096	hsa-miR-650	CLIP-seq
MIRT816097	hsa-miR-939	CLIP-seq
MIRT1941391	hsa-miR-1236	CLIP-seq
MIRT1941392	hsa-miR-1238	CLIP-seq
MIRT1941393	hsa-miR-3124-3p	CLIP-seq
MIRT1941394	hsa-miR-759	CLIP-seq
MIRT2180137	hsa-miR-1233	CLIP-seq
MIRT2180138	hsa-miR-1254	CLIP-seq
MIRT2180139	hsa-miR-128	CLIP-seq
MIRT2180140	hsa-miR-27a	CLIP-seq
MIRT2180141	hsa-miR-27b	CLIP-seq
MIRT2180142	hsa-miR-3116	CLIP-seq
MIRT2180143	hsa-miR-3180-5p	CLIP-seq
MIRT2180144	hsa-miR-3200-3p	CLIP-seq
MIRT2180145	hsa-miR-3667-3p	CLIP-seq
MIRT2180146	hsa-miR-4267	CLIP-seq
MIRT2180147	hsa-miR-4434	CLIP-seq
MIRT2180148	hsa-miR-4436a	CLIP-seq
MIRT2180149	hsa-miR-4516	CLIP-seq
MIRT2180150	hsa-miR-4640-5p	CLIP-seq
MIRT2180151	hsa-miR-4726-5p	CLIP-seq
MIRT2180152	hsa-miR-4768-3p	CLIP-seq
MIRT2180153	hsa-miR-508-5p	CLIP-seq
MIRT2180154	hsa-miR-661	CLIP-seq
MIRT2180155	hsa-miR-766	CLIP-seq
MIRT2180144	hsa-miR-3200-3p	CLIP-seq
MIRT2180145	hsa-miR-3667-3p	CLIP-seq
MIRT816077	hsa-miR-4255	CLIP-seq
MIRT816083	hsa-miR-4637	CLIP-seq
MIRT816090	hsa-miR-4803	CLIP-seq
MIRT816077	hsa-miR-4255	CLIP-seq
MIRT816083	hsa-miR-4637	CLIP-seq
MIRT816090	hsa-miR-4803	CLIP-seq
MIRT2483524	hsa-miR-1207-3p	CLIP-seq
MIRT2483525	hsa-miR-1225-5p	CLIP-seq
MIRT2483526	hsa-miR-1226	CLIP-seq
MIRT2483527	hsa-miR-1228	CLIP-seq
MIRT1941391	hsa-miR-1236	CLIP-seq
MIRT2180138	hsa-miR-1254	CLIP-seq
MIRT2483528	hsa-miR-1265	CLIP-seq
MIRT2180139	hsa-miR-128	CLIP-seq
MIRT2483529	hsa-miR-1293	CLIP-seq
MIRT2483530	hsa-miR-1321	CLIP-seq
MIRT2483531	hsa-miR-1343	CLIP-seq
MIRT2483532	hsa-miR-150	CLIP-seq
MIRT2483533	hsa-miR-1912	CLIP-seq
MIRT2483534	hsa-miR-199a-3p	CLIP-seq
MIRT2483535	hsa-miR-199b-3p	CLIP-seq
MIRT2483536	hsa-miR-2392	CLIP-seq
MIRT2483537	hsa-miR-2467-3p	CLIP-seq
MIRT2180140	hsa-miR-27a	CLIP-seq
MIRT2180141	hsa-miR-27b	CLIP-seq
MIRT2483538	hsa-miR-298	CLIP-seq
MIRT2483539	hsa-miR-3065-3p	CLIP-seq
MIRT2483540	hsa-miR-3115	CLIP-seq
MIRT2180142	hsa-miR-3116	CLIP-seq
MIRT2483541	hsa-miR-3126-5p	CLIP-seq
MIRT2483542	hsa-miR-3129-5p	CLIP-seq
MIRT2483543	hsa-miR-3130-5p	CLIP-seq
MIRT2483544	hsa-miR-3150b-3p	CLIP-seq
MIRT2483545	hsa-miR-3157-5p	CLIP-seq
MIRT2483546	hsa-miR-3158-5p	CLIP-seq
MIRT2483547	hsa-miR-3167	CLIP-seq
MIRT2483548	hsa-miR-3173-3p	CLIP-seq
MIRT2483549	hsa-miR-3174	CLIP-seq
MIRT2180143	hsa-miR-3180-5p	CLIP-seq
MIRT816076	hsa-miR-3612	CLIP-seq
MIRT2483550	hsa-miR-3650	CLIP-seq
MIRT2483551	hsa-miR-3689a-3p	CLIP-seq
MIRT2483552	hsa-miR-3689c	CLIP-seq
MIRT2483553	hsa-miR-3909	CLIP-seq
MIRT2483554	hsa-miR-4419a	CLIP-seq
MIRT2180147	hsa-miR-4434	CLIP-seq
MIRT2180148	hsa-miR-4436a	CLIP-seq
MIRT2483555	hsa-miR-4436b-3p	CLIP-seq
MIRT2483556	hsa-miR-4468	CLIP-seq
MIRT2483557	hsa-miR-4474-3p	CLIP-seq
MIRT2483558	hsa-miR-4482	CLIP-seq
MIRT2483559	hsa-miR-4483	CLIP-seq
MIRT2483560	hsa-miR-4510	CLIP-seq
MIRT2180149	hsa-miR-4516	CLIP-seq
MIRT2180150	hsa-miR-4640-5p	CLIP-seq
MIRT2483561	hsa-miR-4690-3p	CLIP-seq
MIRT2483562	hsa-miR-4691-3p	CLIP-seq
MIRT2483563	hsa-miR-4711-5p	CLIP-seq
MIRT2483564	hsa-miR-4713-5p	CLIP-seq
MIRT2483565	hsa-miR-4725-5p	CLIP-seq
MIRT2180151	hsa-miR-4726-5p	CLIP-seq
MIRT2483566	hsa-miR-4728-5p	CLIP-seq
MIRT2483567	hsa-miR-4739	CLIP-seq
MIRT2483568	hsa-miR-4756-5p	CLIP-seq
MIRT2180152	hsa-miR-4768-3p	CLIP-seq
MIRT2483569	hsa-miR-4784	CLIP-seq
MIRT2483570	hsa-miR-504	CLIP-seq
MIRT2483571	hsa-miR-516a-3p	CLIP-seq
MIRT2483572	hsa-miR-532-3p	CLIP-seq
MIRT2483573	hsa-miR-605	CLIP-seq
MIRT2483574	hsa-miR-644	CLIP-seq
MIRT816096	hsa-miR-650	CLIP-seq
MIRT2180154	hsa-miR-661	CLIP-seq
MIRT2483575	hsa-miR-665	CLIP-seq
MIRT2483576	hsa-miR-876-5p	CLIP-seq
MIRT2483577	hsa-miR-921	CLIP-seq
MIRT2483524	hsa-miR-1207-3p	CLIP-seq
MIRT2483525	hsa-miR-1225-5p	CLIP-seq
MIRT2483526	hsa-miR-1226	CLIP-seq
MIRT2483527	hsa-miR-1228	CLIP-seq
MIRT2180138	hsa-miR-1254	CLIP-seq
MIRT2483528	hsa-miR-1265	CLIP-seq
MIRT2180139	hsa-miR-128	CLIP-seq
MIRT2483529	hsa-miR-1293	CLIP-seq
MIRT2483530	hsa-miR-1321	CLIP-seq
MIRT2483531	hsa-miR-1343	CLIP-seq
MIRT2483532	hsa-miR-150	CLIP-seq
MIRT2483533	hsa-miR-1912	CLIP-seq
MIRT2483534	hsa-miR-199a-3p	CLIP-seq
MIRT2483535	hsa-miR-199b-3p	CLIP-seq
MIRT2483536	hsa-miR-2392	CLIP-seq
MIRT2483537	hsa-miR-2467-3p	CLIP-seq
MIRT2180140	hsa-miR-27a	CLIP-seq
MIRT2180141	hsa-miR-27b	CLIP-seq
MIRT2483538	hsa-miR-298	CLIP-seq
MIRT2483539	hsa-miR-3065-3p	CLIP-seq
MIRT2483540	hsa-miR-3115	CLIP-seq
MIRT2180142	hsa-miR-3116	CLIP-seq
MIRT2483541	hsa-miR-3126-5p	CLIP-seq
MIRT2483542	hsa-miR-3129-5p	CLIP-seq
MIRT2483543	hsa-miR-3130-5p	CLIP-seq
MIRT2483544	hsa-miR-3150b-3p	CLIP-seq
MIRT2483545	hsa-miR-3157-5p	CLIP-seq
MIRT2483546	hsa-miR-3158-5p	CLIP-seq
MIRT2483547	hsa-miR-3167	CLIP-seq
MIRT2483548	hsa-miR-3173-3p	CLIP-seq
MIRT2483549	hsa-miR-3174	CLIP-seq
MIRT2180143	hsa-miR-3180-5p	CLIP-seq
MIRT2675872	hsa-miR-3181	CLIP-seq
MIRT816076	hsa-miR-3612	CLIP-seq
MIRT2483550	hsa-miR-3650	CLIP-seq
MIRT2483551	hsa-miR-3689a-3p	CLIP-seq
MIRT2483552	hsa-miR-3689c	CLIP-seq
MIRT2675873	hsa-miR-3944-3p	CLIP-seq
MIRT2483554	hsa-miR-4419a	CLIP-seq
MIRT2180147	hsa-miR-4434	CLIP-seq
MIRT2180148	hsa-miR-4436a	CLIP-seq
MIRT2483555	hsa-miR-4436b-3p	CLIP-seq
MIRT2483556	hsa-miR-4468	CLIP-seq
MIRT2483557	hsa-miR-4474-3p	CLIP-seq
MIRT2483558	hsa-miR-4482	CLIP-seq
MIRT2483559	hsa-miR-4483	CLIP-seq
MIRT2483560	hsa-miR-4510	CLIP-seq
MIRT2180149	hsa-miR-4516	CLIP-seq
MIRT2180150	hsa-miR-4640-5p	CLIP-seq
MIRT2483561	hsa-miR-4690-3p	CLIP-seq
MIRT2483562	hsa-miR-4691-3p	CLIP-seq
MIRT2675874	hsa-miR-4694-5p	CLIP-seq
MIRT2483563	hsa-miR-4711-5p	CLIP-seq
MIRT2483564	hsa-miR-4713-5p	CLIP-seq
MIRT2483565	hsa-miR-4725-5p	CLIP-seq
MIRT2180151	hsa-miR-4726-5p	CLIP-seq
MIRT2483566	hsa-miR-4728-5p	CLIP-seq
MIRT2483567	hsa-miR-4739	CLIP-seq
MIRT2675875	hsa-miR-4747-3p	CLIP-seq
MIRT2675876	hsa-miR-4750	CLIP-seq
MIRT2483568	hsa-miR-4756-5p	CLIP-seq
MIRT2180152	hsa-miR-4768-3p	CLIP-seq
MIRT2483569	hsa-miR-4784	CLIP-seq
MIRT2483570	hsa-miR-504	CLIP-seq
MIRT2483571	hsa-miR-516a-3p	CLIP-seq
MIRT2483572	hsa-miR-532-3p	CLIP-seq
MIRT2483573	hsa-miR-605	CLIP-seq
MIRT2483574	hsa-miR-644	CLIP-seq
MIRT816096	hsa-miR-650	CLIP-seq
MIRT2180154	hsa-miR-661	CLIP-seq
MIRT2483575	hsa-miR-665	CLIP-seq
MIRT2483576	hsa-miR-876-5p	CLIP-seq
MIRT2483577	hsa-miR-921	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 19060904, 19074269, 21988832, 23661758, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	NAS	23661758
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	NAS	23661758
GO:0030154	Process	Cell differentiation	IEA
GO:0042832	Process	Defense response to protozoan	IEA
GO:0042832	Process	Defense response to protozoan	ISS
GO:0043011	Process	Myeloid dendritic cell differentiation	IEA
GO:0043011	Process	Myeloid dendritic cell differentiation	ISS
GO:0090575	Component	RNA polymerase II transcription regulator complex	IPI	23661758
GO:0140467	Process	Integrated stress response signaling	NAS	28566324

Other IDs

• MIM: 614983
• HGNC: 25163
• e!Ensembl: ENSG00000168062

Protein

• UniProt ID: Q8N1L9
• Protein name: Basic leucine zipper transcriptional factor ATF-like 2 (B-ATF-2) (Suppressor of AP-1 regulated by IFN) (SARI)
• Protein function: AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00170	bZIP_1	15 → 72	bZIP transcription factor	Coiled-coil

• Sequence:

  MHLCGGNGLLTQTDPKEQQRQLKKQKNRAAAQRSRQKHTDKADALHQQHESLEKDNLALR
  KEIQSLQAELAWWSRTLHVHERLCPMDCASCSAPGLLGCWDQAEGLLGPGPQGQHGCREQ
  LELFQTPGSCYPAQPLSPGPQPHDSPSLLQCPLPSLSLGPAVVAEPPVQLSPSPLLFASH
  TGSSLQGSSSKLSALQPSLTAQTAPPQPLELEHPTRGKLGSSPDNPSSALGLARLQSREH
  KPALSAATWQGLVVDPSPHPLLAFPLLSSAQVHF

• Sequence length: 274

Pathways

KEGG:

PD-L1 expression and PD-1 checkpoint pathway in cancer