RAB3C (RAB3C, member RAS oncogene family)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 115827 |
| Gene name | RAB3C, member RAS oncogene family |
| Gene symbol | RAB3C |
| Synonyms (NCBI Gene) |
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| Chromosome | 5 |
| Chromosome location | 5q11.2 |
| Summary | This gene is a member of the RAS oncogene family and encodes a small GTPase. Other similar small GTPases are known to be involved in vesicle trafficking, and the encoded protein was shown to play a role in recycling phagocytosed MHC class 1 complexes to t |
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miRNA
miRNA information provided by mirtarbase database.
354
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
26
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q96E17 | ||||||||||
| Protein name | Ras-related protein Rab-3C (EC 3.6.5.2) | ||||||||||
| Protein function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to r | ||||||||||
| PDB | 6Y7G | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in brain, placenta and lung. {ECO:0000269|PubMed:12296628}. | ||||||||||
| Sequence |
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| Sequence length | 227 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
5
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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