Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
115761
Gene name Gene Name - the full gene name approved by the HGNC.
ARF like GTPase 11
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ARL11
Synonyms (NCBI Gene) Gene synonyms aliases
ARLTS1
Chromosome Chromosome number
13
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
13q14.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancer
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT719233 hsa-miR-4274 HITS-CLIP 19536157
MIRT719232 hsa-miR-6892-3p HITS-CLIP 19536157
MIRT719231 hsa-miR-2276-5p HITS-CLIP 19536157
MIRT719230 hsa-miR-6515-3p HITS-CLIP 19536157
MIRT719229 hsa-miR-1236-3p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 16189514, 19060904, 31515488
GO:0005525 Function GTP binding IBA 21873635
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005886 Component Plasma membrane IBA 21873635
GO:0006886 Process Intracellular protein transport IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
609351 24046 ENSG00000152213
Protein
UniProt ID Q969Q4
Protein name ADP-ribosylation factor-like protein 11 (ADP-ribosylation factor-like tumor suppressor protein 1)
Protein function May play a role in apoptosis. May act as a tumor suppressor.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00025 Arf 3 173 ADP-ribosylation factor family Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in lung and leukocytes. {ECO:0000269|PubMed:15843669}.
Sequence
Sequence length 196
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Ovarian cancer Malignant neoplasm of ovary rs34424986, rs137853060, rs28934575, rs79658334, rs121913021, rs62625308, rs80356898, rs80357579, rs41293497, rs80356904, rs80357471, rs80357522, rs80357234, rs80357912, rs80357828
View all (31 more)
17079447
Unknown
Disease term Disease name Evidence References Source
Multiple Sclerosis Multiple Sclerosis GWAS
Schizophrenia Schizophrenia GWAS
Systemic lupus erythematosus Systemic lupus erythematosus GWAS
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 18337727
Inflammation Associate 29934367
Keratoconus Associate 39300613
Neoplasms Associate 18337727
Neoplasms Inhibit 23940804, 29934367
Prostate cancer familial Associate 18337727
Prostatic Neoplasms Associate 18337727, 23940804
Prostatic Neoplasms Inhibit 23940804