Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	1153
Gene name Gene Name - the full gene name approved by the HGNC.	Cold inducible RNA binding protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CIRBP
Synonyms (NCBI Gene) Gene synonyms aliases	CIRP
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19p13.3

Show/Hide all(145)

miRTarBase ID	miRNA	Experiments	Reference
MIRT028434	hsa-miR-30a-5p	Proteomics	18668040
MIRT030423	hsa-miR-24-3p	Microarray	19748357
MIRT893552	hsa-miR-145	CLIP-seq
MIRT893553	hsa-miR-188-3p	CLIP-seq
MIRT893554	hsa-miR-3148	CLIP-seq
MIRT893555	hsa-miR-3155	CLIP-seq
MIRT893556	hsa-miR-3155b	CLIP-seq
MIRT893557	hsa-miR-3157-5p	CLIP-seq
MIRT893558	hsa-miR-3202	CLIP-seq
MIRT893559	hsa-miR-325	CLIP-seq
MIRT893560	hsa-miR-338-5p	CLIP-seq
MIRT893561	hsa-miR-3610	CLIP-seq
MIRT893562	hsa-miR-377	CLIP-seq
MIRT893563	hsa-miR-383	CLIP-seq
MIRT893564	hsa-miR-3978	CLIP-seq
MIRT893565	hsa-miR-4252	CLIP-seq
MIRT893566	hsa-miR-4468	CLIP-seq
MIRT893567	hsa-miR-4476	CLIP-seq
MIRT893568	hsa-miR-4505	CLIP-seq
MIRT893569	hsa-miR-4529-5p	CLIP-seq
MIRT893570	hsa-miR-4533	CLIP-seq
MIRT893571	hsa-miR-4534	CLIP-seq
MIRT893572	hsa-miR-4643	CLIP-seq
MIRT893573	hsa-miR-466	CLIP-seq
MIRT893574	hsa-miR-4691-3p	CLIP-seq
MIRT893575	hsa-miR-4699-3p	CLIP-seq
MIRT893576	hsa-miR-4712-5p	CLIP-seq
MIRT893577	hsa-miR-4789-3p	CLIP-seq
MIRT893578	hsa-miR-4796-3p	CLIP-seq
MIRT893579	hsa-miR-484	CLIP-seq
MIRT893580	hsa-miR-514	CLIP-seq
MIRT893581	hsa-miR-514b-3p	CLIP-seq
MIRT893582	hsa-miR-526b	CLIP-seq
MIRT893583	hsa-miR-532-3p	CLIP-seq
MIRT893584	hsa-miR-571	CLIP-seq
MIRT893585	hsa-miR-628-3p	CLIP-seq
MIRT893586	hsa-miR-629	CLIP-seq
MIRT893587	hsa-miR-770-5p	CLIP-seq
MIRT893588	hsa-miR-802	CLIP-seq
MIRT893557	hsa-miR-3157-5p	CLIP-seq
MIRT893565	hsa-miR-4252	CLIP-seq
MIRT893571	hsa-miR-4534	CLIP-seq
MIRT893574	hsa-miR-4691-3p	CLIP-seq
MIRT1964907	hsa-miR-1266	CLIP-seq
MIRT1964908	hsa-miR-1276	CLIP-seq
MIRT1964909	hsa-miR-128	CLIP-seq
MIRT1964910	hsa-miR-140-3p	CLIP-seq
MIRT893552	hsa-miR-145	CLIP-seq
MIRT1964911	hsa-miR-27a	CLIP-seq
MIRT1964912	hsa-miR-27b	CLIP-seq
MIRT893554	hsa-miR-3148	CLIP-seq
MIRT893555	hsa-miR-3155	CLIP-seq
MIRT893556	hsa-miR-3155b	CLIP-seq
MIRT893557	hsa-miR-3157-5p	CLIP-seq
MIRT893560	hsa-miR-338-5p	CLIP-seq
MIRT1964913	hsa-miR-3664-3p	CLIP-seq
MIRT893564	hsa-miR-3978	CLIP-seq
MIRT893565	hsa-miR-4252	CLIP-seq
MIRT1964914	hsa-miR-4270	CLIP-seq
MIRT1964915	hsa-miR-4441	CLIP-seq
MIRT893568	hsa-miR-4505	CLIP-seq
MIRT1964916	hsa-miR-4518	CLIP-seq
MIRT893569	hsa-miR-4529-5p	CLIP-seq
MIRT893571	hsa-miR-4534	CLIP-seq
MIRT893574	hsa-miR-4691-3p	CLIP-seq
MIRT893576	hsa-miR-4712-5p	CLIP-seq
MIRT893579	hsa-miR-484	CLIP-seq
MIRT1964917	hsa-miR-513a-5p	CLIP-seq
MIRT1964918	hsa-miR-548b-3p	CLIP-seq
MIRT893584	hsa-miR-571	CLIP-seq
MIRT1964919	hsa-miR-615-5p	CLIP-seq
MIRT893586	hsa-miR-629	CLIP-seq
MIRT893587	hsa-miR-770-5p	CLIP-seq
MIRT2200885	hsa-miR-1178	CLIP-seq
MIRT1964908	hsa-miR-1276	CLIP-seq
MIRT1964909	hsa-miR-128	CLIP-seq
MIRT1964910	hsa-miR-140-3p	CLIP-seq
MIRT893552	hsa-miR-145	CLIP-seq
MIRT893553	hsa-miR-188-3p	CLIP-seq
MIRT1964911	hsa-miR-27a	CLIP-seq
MIRT1964912	hsa-miR-27b	CLIP-seq
MIRT893554	hsa-miR-3148	CLIP-seq
MIRT2200886	hsa-miR-3151	CLIP-seq
MIRT893555	hsa-miR-3155	CLIP-seq
MIRT893556	hsa-miR-3155b	CLIP-seq
MIRT893557	hsa-miR-3157-5p	CLIP-seq
MIRT2200887	hsa-miR-3174	CLIP-seq
MIRT893558	hsa-miR-3202	CLIP-seq
MIRT893560	hsa-miR-338-5p	CLIP-seq
MIRT893563	hsa-miR-383	CLIP-seq
MIRT2200888	hsa-miR-3919	CLIP-seq
MIRT893564	hsa-miR-3978	CLIP-seq
MIRT893565	hsa-miR-4252	CLIP-seq
MIRT2200889	hsa-miR-4330	CLIP-seq
MIRT2200890	hsa-miR-4481	CLIP-seq
MIRT893568	hsa-miR-4505	CLIP-seq
MIRT893570	hsa-miR-4533	CLIP-seq
MIRT893572	hsa-miR-4643	CLIP-seq
MIRT893573	hsa-miR-466	CLIP-seq
MIRT893574	hsa-miR-4691-3p	CLIP-seq
MIRT2200891	hsa-miR-4695-3p	CLIP-seq
MIRT893576	hsa-miR-4712-5p	CLIP-seq
MIRT2200892	hsa-miR-4745-5p	CLIP-seq
MIRT2200893	hsa-miR-4756-3p	CLIP-seq
MIRT2200894	hsa-miR-4758-5p	CLIP-seq
MIRT893577	hsa-miR-4789-3p	CLIP-seq
MIRT893579	hsa-miR-484	CLIP-seq
MIRT2200895	hsa-miR-486-3p	CLIP-seq
MIRT1964917	hsa-miR-513a-5p	CLIP-seq
MIRT893580	hsa-miR-514	CLIP-seq
MIRT893581	hsa-miR-514b-3p	CLIP-seq
MIRT893583	hsa-miR-532-3p	CLIP-seq
MIRT2200896	hsa-miR-548a-3p	CLIP-seq
MIRT2200897	hsa-miR-548e	CLIP-seq
MIRT2200898	hsa-miR-548f	CLIP-seq
MIRT893584	hsa-miR-571	CLIP-seq
MIRT893586	hsa-miR-629	CLIP-seq
MIRT893587	hsa-miR-770-5p	CLIP-seq
MIRT2200885	hsa-miR-1178	CLIP-seq
MIRT1964908	hsa-miR-1276	CLIP-seq
MIRT1964909	hsa-miR-128	CLIP-seq
MIRT1964910	hsa-miR-140-3p	CLIP-seq
MIRT893552	hsa-miR-145	CLIP-seq
MIRT1964911	hsa-miR-27a	CLIP-seq
MIRT1964912	hsa-miR-27b	CLIP-seq
MIRT2503734	hsa-miR-3064-3p	CLIP-seq
MIRT893554	hsa-miR-3148	CLIP-seq
MIRT893557	hsa-miR-3157-5p	CLIP-seq
MIRT893564	hsa-miR-3978	CLIP-seq
MIRT893565	hsa-miR-4252	CLIP-seq
MIRT893571	hsa-miR-4534	CLIP-seq
MIRT893574	hsa-miR-4691-3p	CLIP-seq
MIRT893576	hsa-miR-4712-5p	CLIP-seq
MIRT1964917	hsa-miR-513a-5p	CLIP-seq
MIRT893584	hsa-miR-571	CLIP-seq
MIRT1964919	hsa-miR-615-5p	CLIP-seq
MIRT893587	hsa-miR-770-5p	CLIP-seq
MIRT2200885	hsa-miR-1178	CLIP-seq
MIRT1964908	hsa-miR-1276	CLIP-seq
MIRT1964910	hsa-miR-140-3p	CLIP-seq
MIRT2503734	hsa-miR-3064-3p	CLIP-seq
MIRT893554	hsa-miR-3148	CLIP-seq
MIRT893564	hsa-miR-3978	CLIP-seq
MIRT893584	hsa-miR-571	CLIP-seq
MIRT1964919	hsa-miR-615-5p	CLIP-seq

Show/Hide all(27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IBA
GO:0003723	Function	RNA binding	IEA
GO:0003730	Function	MRNA 3'-UTR binding	IDA	11574538, 16513844
GO:0005515	Function	Protein binding	IPI	16189514, 16513844, 16713569, 21516116, 22365833, 25416956, 29892012, 31515488, 32296183, 32814053
GO:0005634	Component	Nucleus	HDA	16791210
GO:0005634	Component	Nucleus	IDA	11574538
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005681	Component	Spliceosomal complex	IBA
GO:0005737	Component	Cytoplasm	IDA	11574538
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0009409	Process	Response to cold	IEA
GO:0009409	Process	Response to cold	TAS	9151692
GO:0009411	Process	Response to UV	IDA	11574538
GO:0010494	Component	Cytoplasmic stress granule	ISS
GO:0017148	Process	Negative regulation of translation	IEA
GO:0030371	Function	Translation repressor activity	ISS
GO:0034063	Process	Stress granule assembly	ISS
GO:0045727	Process	Positive regulation of translation	IDA	11574538
GO:0048026	Process	Positive regulation of mRNA splicing, via spliceosome	IBA
GO:0048255	Process	MRNA stabilization	IDA	11574538
GO:0070181	Function	Small ribosomal subunit rRNA binding	IDA	11574538

MIM	HGNC	e!Ensembl
602649	1982	ENSG00000099622

Protein

UniProt ID

Q14011

Protein name

Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP)

Protein function

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced s

PDB

1X5S , 5TBX , 8CMK

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00076	RRM_1	8 → 78	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous.

Sequence

MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDA
KDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGGGD
RGYGGNRFESRSGGYGGSRDYYSSRSQSGGYSDRSSGGSYRDSYDSYATHNE

Sequence length

172

Interactions

View interactions

CIRBP (cold inducible RNA binding protein)