Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	115019
Gene name Gene Name - the full gene name approved by the HGNC.	Solute carrier family 26 member 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SLC26A9
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q32.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns.

Show/Hide all(213)

miRTarBase ID	miRNA	Experiments	Reference
MIRT646128	hsa-miR-618	HITS-CLIP	23824327
MIRT646127	hsa-miR-4640-3p	HITS-CLIP	23824327
MIRT646126	hsa-miR-6871-3p	HITS-CLIP	23824327
MIRT646125	hsa-miR-3065-3p	HITS-CLIP	23824327
MIRT646124	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT646123	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT646122	hsa-miR-302b-5p	HITS-CLIP	23824327
MIRT646121	hsa-miR-302d-5p	HITS-CLIP	23824327
MIRT646119	hsa-miR-4764-3p	HITS-CLIP	23824327
MIRT646120	hsa-miR-548s	HITS-CLIP	23824327
MIRT646118	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT646117	hsa-miR-588	HITS-CLIP	23824327
MIRT646116	hsa-miR-4435	HITS-CLIP	23824327
MIRT646115	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT483602	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT483600	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT483599	hsa-miR-4476	PAR-CLIP	23592263
MIRT483598	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT483597	hsa-miR-1321	PAR-CLIP	23592263
MIRT483596	hsa-miR-4739	PAR-CLIP	23592263
MIRT483595	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT483594	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT483593	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT483592	hsa-miR-7515	PAR-CLIP	23592263
MIRT483591	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT483589	hsa-miR-4784	PAR-CLIP	23592263
MIRT483590	hsa-miR-3202	PAR-CLIP	23592263
MIRT483588	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT483587	hsa-miR-4306	PAR-CLIP	23592263
MIRT483586	hsa-miR-4644	PAR-CLIP	23592263
MIRT483585	hsa-miR-765	PAR-CLIP	23592263
MIRT483584	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT483583	hsa-miR-8085	PAR-CLIP	23592263
MIRT483582	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT483580	hsa-miR-3175	PAR-CLIP	23592263
MIRT483581	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT483579	hsa-miR-5698	PAR-CLIP	23592263
MIRT483578	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT483577	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT483602	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT483600	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT483599	hsa-miR-4476	PAR-CLIP	23592263
MIRT483598	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT483597	hsa-miR-1321	PAR-CLIP	23592263
MIRT483596	hsa-miR-4739	PAR-CLIP	23592263
MIRT483595	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT483594	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT483593	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT483592	hsa-miR-7515	PAR-CLIP	23592263
MIRT483591	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT483589	hsa-miR-4784	PAR-CLIP	23592263
MIRT483590	hsa-miR-3202	PAR-CLIP	23592263
MIRT483588	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT483587	hsa-miR-4306	PAR-CLIP	23592263
MIRT483586	hsa-miR-4644	PAR-CLIP	23592263
MIRT483585	hsa-miR-765	PAR-CLIP	23592263
MIRT483584	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT483583	hsa-miR-8085	PAR-CLIP	23592263
MIRT483582	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT483580	hsa-miR-3175	PAR-CLIP	23592263
MIRT483581	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT483579	hsa-miR-5698	PAR-CLIP	23592263
MIRT483578	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT483577	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT483588	hsa-miR-185-5p	PAR-CLIP	26701625
MIRT483591	hsa-miR-3150b-3p	PAR-CLIP	26701625
MIRT483580	hsa-miR-3175	PAR-CLIP	26701625
MIRT483587	hsa-miR-4306	PAR-CLIP	26701625
MIRT483586	hsa-miR-4644	PAR-CLIP	26701625
MIRT483594	hsa-miR-4716-3p	PAR-CLIP	26701625
MIRT483581	hsa-miR-4723-5p	PAR-CLIP	26701625
MIRT483589	hsa-miR-4784	PAR-CLIP	26701625
MIRT483579	hsa-miR-5698	PAR-CLIP	26701625
MIRT483584	hsa-miR-6731-5p	PAR-CLIP	26701625
MIRT483602	hsa-miR-6758-5p	PAR-CLIP	26701625
MIRT483593	hsa-miR-6794-5p	PAR-CLIP	26701625
MIRT483600	hsa-miR-6856-5p	PAR-CLIP	26701625
MIRT483578	hsa-miR-6870-5p	PAR-CLIP	26701625
MIRT483577	hsa-miR-7111-5p	PAR-CLIP	26701625
MIRT483583	hsa-miR-8085	PAR-CLIP	26701625
MIRT646128	hsa-miR-618	HITS-CLIP	23824327
MIRT646127	hsa-miR-4640-3p	HITS-CLIP	23824327
MIRT646126	hsa-miR-6871-3p	HITS-CLIP	23824327
MIRT646125	hsa-miR-3065-3p	HITS-CLIP	23824327
MIRT646124	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT646123	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT646122	hsa-miR-302b-5p	HITS-CLIP	23824327
MIRT646121	hsa-miR-302d-5p	HITS-CLIP	23824327
MIRT646119	hsa-miR-4764-3p	HITS-CLIP	23824327
MIRT646120	hsa-miR-548s	HITS-CLIP	23824327
MIRT646118	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT646117	hsa-miR-588	HITS-CLIP	23824327
MIRT646116	hsa-miR-4435	HITS-CLIP	23824327
MIRT646115	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT483602	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT483600	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT483599	hsa-miR-4476	PAR-CLIP	23592263
MIRT483598	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT483597	hsa-miR-1321	PAR-CLIP	23592263
MIRT483596	hsa-miR-4739	PAR-CLIP	23592263
MIRT483595	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT483594	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT483593	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT483592	hsa-miR-7515	PAR-CLIP	23592263
MIRT483591	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT483589	hsa-miR-4784	PAR-CLIP	23592263
MIRT483590	hsa-miR-3202	PAR-CLIP	23592263
MIRT483588	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT483587	hsa-miR-4306	PAR-CLIP	23592263
MIRT483586	hsa-miR-4644	PAR-CLIP	23592263
MIRT483585	hsa-miR-765	PAR-CLIP	23592263
MIRT483584	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT483583	hsa-miR-8085	PAR-CLIP	23592263
MIRT483582	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT483580	hsa-miR-3175	PAR-CLIP	23592263
MIRT483581	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT483579	hsa-miR-5698	PAR-CLIP	23592263
MIRT483578	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT483577	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT483602	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT483600	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT483599	hsa-miR-4476	PAR-CLIP	23592263
MIRT483598	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT483597	hsa-miR-1321	PAR-CLIP	23592263
MIRT483596	hsa-miR-4739	PAR-CLIP	23592263
MIRT483595	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT483594	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT483593	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT483592	hsa-miR-7515	PAR-CLIP	23592263
MIRT483591	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT483589	hsa-miR-4784	PAR-CLIP	23592263
MIRT483590	hsa-miR-3202	PAR-CLIP	23592263
MIRT483588	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT483587	hsa-miR-4306	PAR-CLIP	23592263
MIRT483586	hsa-miR-4644	PAR-CLIP	23592263
MIRT483585	hsa-miR-765	PAR-CLIP	23592263
MIRT483584	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT483583	hsa-miR-8085	PAR-CLIP	23592263
MIRT483582	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT483580	hsa-miR-3175	PAR-CLIP	23592263
MIRT483581	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT483579	hsa-miR-5698	PAR-CLIP	23592263
MIRT483578	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT483577	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT1357963	hsa-miR-1200	CLIP-seq
MIRT1357964	hsa-miR-1270	CLIP-seq
MIRT1357965	hsa-miR-1297	CLIP-seq
MIRT1357966	hsa-miR-1305	CLIP-seq
MIRT1357967	hsa-miR-185	CLIP-seq
MIRT1357968	hsa-miR-2467-5p	CLIP-seq
MIRT1357969	hsa-miR-26a	CLIP-seq
MIRT1357970	hsa-miR-26b	CLIP-seq
MIRT1357971	hsa-miR-3188	CLIP-seq
MIRT1357972	hsa-miR-345	CLIP-seq
MIRT1357973	hsa-miR-3975	CLIP-seq
MIRT1357974	hsa-miR-3978	CLIP-seq
MIRT1357975	hsa-miR-4324	CLIP-seq
MIRT1357976	hsa-miR-4465	CLIP-seq
MIRT1357977	hsa-miR-4643	CLIP-seq
MIRT1357978	hsa-miR-4649-3p	CLIP-seq
MIRT1357979	hsa-miR-466	CLIP-seq
MIRT1357980	hsa-miR-4683	CLIP-seq
MIRT1357981	hsa-miR-4706	CLIP-seq
MIRT1357982	hsa-miR-4708-5p	CLIP-seq
MIRT1357983	hsa-miR-4717-3p	CLIP-seq
MIRT1357984	hsa-miR-4728-5p	CLIP-seq
MIRT1357985	hsa-miR-4749-5p	CLIP-seq
MIRT1357986	hsa-miR-4789-3p	CLIP-seq
MIRT1357987	hsa-miR-4802-3p	CLIP-seq
MIRT1357988	hsa-miR-485-5p	CLIP-seq
MIRT1357989	hsa-miR-498	CLIP-seq
MIRT1357990	hsa-miR-544b	CLIP-seq
MIRT1357991	hsa-miR-620	CLIP-seq
MIRT1357992	hsa-miR-744	CLIP-seq
MIRT1357993	hsa-miR-760	CLIP-seq
MIRT1357994	hsa-miR-890	CLIP-seq
MIRT1357995	hsa-miR-3161	CLIP-seq
MIRT1357996	hsa-miR-3929	CLIP-seq
MIRT1357997	hsa-miR-4419b	CLIP-seq
MIRT1357998	hsa-miR-4438	CLIP-seq
MIRT1357999	hsa-miR-4478	CLIP-seq
MIRT1357993	hsa-miR-760	CLIP-seq
MIRT1357963	hsa-miR-1200	CLIP-seq
MIRT1357968	hsa-miR-2467-5p	CLIP-seq
MIRT1357971	hsa-miR-3188	CLIP-seq
MIRT1357972	hsa-miR-345	CLIP-seq
MIRT1357973	hsa-miR-3975	CLIP-seq
MIRT1357974	hsa-miR-3978	CLIP-seq
MIRT1357975	hsa-miR-4324	CLIP-seq
MIRT1357978	hsa-miR-4649-3p	CLIP-seq
MIRT2106020	hsa-miR-4714-5p	CLIP-seq
MIRT1357988	hsa-miR-485-5p	CLIP-seq
MIRT1357990	hsa-miR-544b	CLIP-seq
MIRT1357993	hsa-miR-760	CLIP-seq
MIRT1357994	hsa-miR-890	CLIP-seq
MIRT2330370	hsa-miR-3152-5p	CLIP-seq
MIRT2330371	hsa-miR-4519	CLIP-seq
MIRT1357978	hsa-miR-4649-3p	CLIP-seq
MIRT2330372	hsa-miR-4774-3p	CLIP-seq
MIRT1357988	hsa-miR-485-5p	CLIP-seq
MIRT2394692	hsa-miR-2467-3p	CLIP-seq
MIRT2394693	hsa-miR-3678-3p	CLIP-seq
MIRT2394694	hsa-miR-4292	CLIP-seq
MIRT1357965	hsa-miR-1297	CLIP-seq
MIRT1357966	hsa-miR-1305	CLIP-seq
MIRT1357969	hsa-miR-26a	CLIP-seq
MIRT1357970	hsa-miR-26b	CLIP-seq
MIRT2466047	hsa-miR-296-3p	CLIP-seq
MIRT2466048	hsa-miR-421	CLIP-seq
MIRT1357976	hsa-miR-4465	CLIP-seq
MIRT2466049	hsa-miR-4709-5p	CLIP-seq
MIRT1357989	hsa-miR-498	CLIP-seq
MIRT2466050	hsa-miR-505	CLIP-seq

Show/Hide all(29)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IDA	26801567
GO:0005254	Function	Chloride channel activity	IDA	17673510, 18769029, 19289574, 20658517, 22544634, 32818062
GO:0005254	Function	Chloride channel activity	TAS
GO:0005452	Function	Solute:inorganic anion antiporter activity	IDA	15800055, 22544634
GO:0005515	Function	Protein binding	IPI	28360110
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	26801567
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	26801567
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006811	Process	Monoatomic ion transport	TAS
GO:0006820	Process	Monoatomic anion transport	IDA	17673510
GO:0006821	Process	Chloride transport	IDA	17673510, 18769029, 20658517, 22544634
GO:0009986	Component	Cell surface	IDA	17673510, 20658517, 22544634
GO:0010008	Component	Endosome membrane	IDA	26801567
GO:0010628	Process	Positive regulation of gene expression	IDA	20658517
GO:0012505	Component	Endomembrane system	IEA
GO:0015116	Function	Sulfate transmembrane transporter activity	IBA
GO:0016020	Component	Membrane	IEA
GO:0016324	Component	Apical plasma membrane	IDA	20658517
GO:0019531	Function	Oxalate transmembrane transporter activity	IBA
GO:0019532	Process	Oxalate transport	IEA
GO:0051117	Function	ATPase binding	IPI	19289574, 20658517
GO:0055085	Process	Transmembrane transport	IEA
GO:0070062	Component	Extracellular exosome	HDA	19199708
GO:0140900	Function	Chloride:bicarbonate antiporter activity	IBA
GO:1902358	Process	Sulfate transmembrane transport	IBA
GO:1902476	Process	Chloride transmembrane transport	IBA
GO:1902476	Process	Chloride transmembrane transport	IDA	15800055

MIM	HGNC	e!Ensembl
608481	14469	ENSG00000174502

Protein

UniProt ID

Q7LBE3

Protein name

Solute carrier family 26 member 9 (Anion transporter/exchanger protein 9)

Protein function

Ion transporter that can act both as an ion channel and anion exchanger (PubMed:15800055, PubMed:17673510, PubMed:26801567, PubMed:32818062). Mainly acts as a chloride channel, which mediate uncoupled chloride anion transport in an alternate-acc

PDB

7CH1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00916	Sulfate_transp	71 → 469	Sulfate permease family	Family
PF01740	STAS	520 → 733	STAS domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Predominantly expressed in lung at the luminal side of the bronchiolar and alveolar epithelium of lung. To a lower extent, also expressed in pancreas and prostate. {ECO:0000269|PubMed:11834742}.

Sequence

MSQPRPRYVVDRAAYSLTLFDDEFEKKDRTYPVGEKLRNAFRCSSAKIKAVVFGLLPVLS
WLPKYKIKDYIIPDLLGGLSGGSIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGV
HQMVPGTFAVISILVGNICLQLAPESKFQVFNNATNESYVDTAAMEAERLHVSATLACLT
AIIQMGLGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFT
FIDICKNLPHTNIASLIFALISGAFLVLVKELNARYMHKIRFPIPTEMIVVVVATAISGG
CKMPKKYHMQIVGEIQRGFPTPVSPVVSQWKDMIGTAFSLAIVSYVINLAMGRTLANKHG
YDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITML
VLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCIWVVSFLSSFFLSLPY
GVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVNPKTYNRAQDIQGIKIITYCSPLYF
ANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRRMRPTQQRRSLFMKTKTVSLQELQQ
DFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQSEPPASAEAPGEPSDMLASVPPFV
TFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFEDGS
LECKHVFPSIHDAVLFAQANARDVTPGHNFQGAPGDAELSLYDSEEDIRSYWDLEQEMFG
SMFHAETLTAL

Sequence length

791

Interactions

View interactions

	KEGG		Reactome
	Mineral absorption Chemical carcinogenesis - reactive oxygen species		Multifunctional anion exchangers

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Cystic Fibrosis	cystic fibrosis	N/A	N/A	GenCC

Show/Hide Text Mining Associations (12)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma	Associate	33832101
Asthma	Associate	34884866, 35328418
Autoimmune Diseases	Associate	34944008
Bronchiectasis	Associate	34884866
Cystic Fibrosis	Associate	23670970, 24550193, 25771386, 28171547, 30716472, 30807572, 31581148, 31697830, 33674211, 34884866, 36206743
Diabetes Mellitus	Associate	23670970, 31581148
Exocrine Pancreatic Insufficiency	Associate	25771386
Huntington Disease	Associate	22466613
Inflammation	Associate	34884866
Lung Diseases	Associate	28171547
Meconium Ileus	Associate	22466613, 30807572
Neuroendocrine Tumors	Associate	34944008

SLC26A9 (solute carrier family 26 member 9)