Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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114907
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
F-box protein 32 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
FBXO32 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
Fbx32, MAFbx |
Chromosome
Chromosome number
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8 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
8q24.13 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Atrial fibrillation |
Atrial Fibrillation |
rs120074192, rs121908590, rs121908593, rs121434558, rs587776851, rs387906612, rs387906613, rs387906614, rs387906615, rs199472687, rs199472705, rs199473324, rs587777336, rs587777339, rs587777557, rs587777558, rs587777559, rs587777560, rs886037778, rs769405762, rs770372675 View all (6 more) |
29892015, 30061737 |
Glaucoma |
Glaucoma, Open-Angle |
rs121918355, rs1566660365, rs1566635134, rs121918356, rs1566634475, rs28936700, rs55771538, rs28936701, rs104893622, rs55989760, rs72549387, rs104893628, rs2125316417, rs104893629, rs74315328, rs121909193, rs74315330, rs74315329, rs74315332, rs74315334, rs74315336, rs74315338, rs74315341, rs121909194, rs74315331, rs1558603396, rs387907175, rs587778873, rs587778875, rs104894979, rs137854895, rs766425037, rs72549380, rs148542782, rs541217363, rs753021890, rs771076928, rs56010818, rs777678299, rs1446110883, rs1573274915, rs1587545234, rs751768343, rs944452644 View all (29 more) |
29891935 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Paroxysmal atrial fibrillation |
Paroxysmal atrial fibrillation |
|
30061737, 29892015 |
ClinVar |
Myopathy |
dilated cardiomyopathy |
|
|
GenCC |
Atrial Fibrillation |
Atrial Fibrillation |
|
|
GWAS |
Neuroblastoma |
Neuroblastoma |
Loss of SNAI2 function reduces self-renewal, 3D invasion as well as metastatic spread in vivo, while strongly sensitizing neuroblastoma cells to RA-induced growth inhibition. |
|
GWAS, CBGDA |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Arthritis Rheumatoid |
Stimulate
|
29129636 |
Atrophy |
Associate
|
15100091, 16916907, 18240972, 22518834, 27526027, 28947926, 37335026 |
Breast Neoplasms |
Associate
|
17437993, 34197655 |
Burns |
Stimulate
|
23816995 |
Carcinogenesis |
Inhibit
|
32516567 |
Carcinoma Pancreatic Ductal |
Stimulate
|
35046938 |
Cardiomyopathy Dilated |
Associate
|
26753747, 36344977 |
Colorectal Neoplasms |
Associate
|
29465067 |
Cryopyrin Associated Periodic Syndromes |
Stimulate
|
37380094 |
Diabetes Mellitus |
Associate
|
20966391 |
Endometrial Neoplasms |
Associate
|
34854395, 35832124 |
Esophageal Squamous Cell Carcinoma |
Inhibit
|
24798237 |
Glioma |
Associate
|
36961398 |
Heart Failure |
Stimulate
|
21098579 |
Hemangioma capillary infantile |
Associate
|
36181115 |
Hypertrophy |
Stimulate
|
16916907 |
Hypoxia |
Stimulate
|
24200883 |
Idiopathic Pulmonary Fibrosis |
Associate
|
20451601 |
Inflammation |
Associate
|
39946176 |
Ischemia |
Associate
|
22761181 |
Lower Extremity Deformities Congenital |
Stimulate
|
20538844 |
Lung Neoplasms |
Associate
|
30697967 |
Male Infertility with Large Headed Multiflagellar Polyploid Spermatozoa |
Associate
|
24803180 |
Multiple Myeloma |
Associate
|
32975519 |
Muscular Atrophy |
Associate
|
15100091, 21098579, 21304964, 23844868, 29364489, 30901379, 31016887, 32871759, 34854395, 35204692, 35454154, 35565825, 35704697, 35736168, 36764073, 38004107, 39946176 View all (2 more) |
Muscular Atrophy |
Stimulate
|
23284670 |
Muscular Disorders Atrophic |
Stimulate
|
23284670 |
Myocardial Infarction |
Associate
|
31698570 |
Myositis |
Associate
|
39946176 |
Myotonia with Skeletal Abnormalities and Mental Retardation |
Associate
|
30901379 |
Myotonic Dystrophy |
Associate
|
30901379 |
Neoplasm Metastasis |
Associate
|
21300763 |
Neoplasms |
Inhibit
|
35316572 |
Osteosarcoma |
Associate
|
37227155 |
Ovarian Neoplasms |
Associate
|
21540640 |
Pancreatic Neoplasms |
Associate
|
34606473 |
Pancreatic Neoplasms |
Stimulate
|
35146962 |
Prostatic Neoplasms |
Associate
|
21652578 |
Pulmonary Disease Chronic Obstructive |
Associate
|
19717478, 25339614, 27526027 |
Pulmonary Disease Chronic Obstructive |
Stimulate
|
22518834, 23844868 |
Pulmonary Disease Chronic Obstructive |
Inhibit
|
27680944 |
Smoke Inhalation Injury |
Stimulate
|
17609255 |
Spinal Cord Injuries |
Stimulate
|
17218363 |
Squamous Cell Carcinoma of Head and Neck |
Associate
|
21300763, 27713166 |
Stomach Neoplasms |
Inhibit
|
23861230 |
Systemic Inflammatory Response Syndrome |
Associate
|
31016887 |
|