Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	114805
Gene name Gene Name - the full gene name approved by the HGNC.	Polypeptide N-acetylgalactosaminyltransferase 13
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	GALNT13
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2q23.3
Summary Summary of gene provided in NCBI Entrez Gene.	The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-ace

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miRTarBase ID	miRNA	Experiments	Reference
MIRT643959	hsa-miR-561-3p	HITS-CLIP	23824327
MIRT643958	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT643957	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT643956	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT643955	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT643954	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT643959	hsa-miR-561-3p	HITS-CLIP	23824327
MIRT643958	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT643957	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT643956	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT643955	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT643954	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT1010903	hsa-let-7a	CLIP-seq
MIRT1010904	hsa-let-7b	CLIP-seq
MIRT1010905	hsa-let-7c	CLIP-seq
MIRT1010906	hsa-let-7d	CLIP-seq
MIRT1010907	hsa-let-7e	CLIP-seq
MIRT1010908	hsa-let-7f	CLIP-seq
MIRT1010909	hsa-let-7g	CLIP-seq
MIRT1010910	hsa-let-7i	CLIP-seq
MIRT1010911	hsa-miR-196a	CLIP-seq
MIRT1010912	hsa-miR-196b	CLIP-seq
MIRT1010913	hsa-miR-203	CLIP-seq
MIRT1010914	hsa-miR-223	CLIP-seq
MIRT1010915	hsa-miR-23a	CLIP-seq
MIRT1010916	hsa-miR-23b	CLIP-seq
MIRT1010917	hsa-miR-23c	CLIP-seq
MIRT1010918	hsa-miR-3065-5p	CLIP-seq
MIRT1010919	hsa-miR-3617	CLIP-seq
MIRT1010920	hsa-miR-3662	CLIP-seq
MIRT1010921	hsa-miR-3909	CLIP-seq
MIRT1010922	hsa-miR-3920	CLIP-seq
MIRT1010923	hsa-miR-3978	CLIP-seq
MIRT1010924	hsa-miR-4274	CLIP-seq
MIRT1010925	hsa-miR-4282	CLIP-seq
MIRT1010926	hsa-miR-4421	CLIP-seq
MIRT1010927	hsa-miR-4450	CLIP-seq
MIRT1010928	hsa-miR-4458	CLIP-seq
MIRT1010929	hsa-miR-4475	CLIP-seq
MIRT1010930	hsa-miR-4500	CLIP-seq
MIRT1010931	hsa-miR-4519	CLIP-seq
MIRT1010932	hsa-miR-4677-3p	CLIP-seq
MIRT1010933	hsa-miR-4697-3p	CLIP-seq
MIRT1010934	hsa-miR-4698	CLIP-seq
MIRT1010935	hsa-miR-4765	CLIP-seq
MIRT1010936	hsa-miR-4799-5p	CLIP-seq
MIRT1010937	hsa-miR-500a	CLIP-seq
MIRT1010938	hsa-miR-501-5p	CLIP-seq
MIRT1010939	hsa-miR-509-3p	CLIP-seq
MIRT1010940	hsa-miR-5096	CLIP-seq
MIRT1010941	hsa-miR-548c-3p	CLIP-seq
MIRT1010942	hsa-miR-548p	CLIP-seq
MIRT1010943	hsa-miR-586	CLIP-seq
MIRT1010944	hsa-miR-590-3p	CLIP-seq
MIRT1010945	hsa-miR-591	CLIP-seq
MIRT1010946	hsa-miR-641	CLIP-seq
MIRT1010947	hsa-miR-656	CLIP-seq
MIRT1010948	hsa-miR-877	CLIP-seq
MIRT1010949	hsa-miR-98	CLIP-seq
MIRT1999394	hsa-miR-124	CLIP-seq
MIRT1999395	hsa-miR-3185	CLIP-seq
MIRT1999396	hsa-miR-34c-3p	CLIP-seq
MIRT1999397	hsa-miR-3611	CLIP-seq
MIRT1999398	hsa-miR-3691-3p	CLIP-seq
MIRT1999399	hsa-miR-3910	CLIP-seq
MIRT1010927	hsa-miR-4450	CLIP-seq
MIRT1999400	hsa-miR-4476	CLIP-seq
MIRT1999401	hsa-miR-4703-3p	CLIP-seq
MIRT1999402	hsa-miR-506	CLIP-seq
MIRT2233065	hsa-miR-1323	CLIP-seq
MIRT2233066	hsa-miR-4666-5p	CLIP-seq
MIRT2233067	hsa-miR-548o	CLIP-seq
MIRT1010944	hsa-miR-590-3p	CLIP-seq
MIRT2450024	hsa-miR-3143	CLIP-seq
MIRT2450025	hsa-miR-3163	CLIP-seq
MIRT2450026	hsa-miR-340	CLIP-seq
MIRT2450027	hsa-miR-3646	CLIP-seq
MIRT2450028	hsa-miR-3647-3p	CLIP-seq
MIRT1010920	hsa-miR-3662	CLIP-seq
MIRT2450029	hsa-miR-376c	CLIP-seq
MIRT1010925	hsa-miR-4282	CLIP-seq
MIRT2450030	hsa-miR-4645-3p	CLIP-seq
MIRT2450031	hsa-miR-4659a-5p	CLIP-seq
MIRT2450032	hsa-miR-4659b-5p	CLIP-seq
MIRT2450033	hsa-miR-4742-3p	CLIP-seq
MIRT2450034	hsa-miR-4776-3p	CLIP-seq
MIRT2450035	hsa-miR-4803	CLIP-seq
MIRT1010941	hsa-miR-548c-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0004653	Function	Polypeptide N-acetylgalactosaminyltransferase activity	IBA
GO:0004653	Function	Polypeptide N-acetylgalactosaminyltransferase activity	IDA	22186971
GO:0004653	Function	Polypeptide N-acetylgalactosaminyltransferase activity	IEA
GO:0004653	Function	Polypeptide N-acetylgalactosaminyltransferase activity	TAS
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IEA
GO:0006486	Process	Protein glycosylation	IEA
GO:0006493	Process	Protein O-linked glycosylation	IBA
GO:0006493	Process	Protein O-linked glycosylation	IEA
GO:0016020	Component	Membrane	IEA
GO:0016266	Process	Protein O-linked glycosylation via N-acetyl-galactosamine	IEA
GO:0016266	Process	Protein O-linked glycosylation via N-acetyl-galactosamine	TAS
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0030246	Function	Carbohydrate binding	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
608369	23242	ENSG00000144278

Protein

UniProt ID

Q8IUC8

Protein name

Polypeptide N-acetylgalactosaminyltransferase 13 (EC 2.4.1.41) (Polypeptide GalNAc transferase 13) (GalNAc-T13) (pp-GaNTase 13) (Protein-UDP acetylgalactosaminyltransferase 13) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13)

Protein function

Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine (GalNAc) residue from UDP-GalNAc to a serine or threonine residue on the protein receptor (PubMed:12407114, PubMed:22186971). Ge

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00535	Glycos_transf_2	118 → 302	Glycosyl transferase family 2	Family
PF00652	Ricin_B_lectin	429 → 547	Ricin-type beta-trefoil lectin domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Specifically expressed in neuronal cells. Expressed in fetal brain, whole adult brain, cerebral cortex and cerebellum. Not expressed in other tissues tested. {ECO:0000269|PubMed:12407114}.

Sequence

MRRFVYCKVVLATSLMWVLVDVFLLLYFSECNKCDDKKERSLLPALRAVISRNQEGPGEM
GKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVV
IVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKNLEVPVKII
RMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVI
SDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRN
YFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHV
INKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPD
SQIPRRYYSLGEIRNVETNQCLDNMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTDDL
CLDVSRLNGPVIMLKCHHMRGNQLWEYDAERLTLRHVNSNQCLDEPSEEDKMVPTMQDCS
GSRSQQWLLRNMTLGT

Sequence length

556

Interactions

View interactions

	KEGG		Reactome
	Mucin type O-glycan biosynthesis Other types of O-glycan biosynthesis Metabolic pathways		O-linked glycosylation of mucins

Show/Hide Unknown Diseases (5)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or gastroesophageal reflux disease	N/A	N/A	GWAS
Astrocytoma	Astrocytoma	N/A	N/A	GWAS
Glioblastoma	Glioblastoma	N/A	N/A	GWAS
Metabolic Syndrome	Metabolic syndrome	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (10)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	36575396
Anemia Sickle Cell	Associate	22679008
Anxiety	Associate	35577822
Glioma	Associate	18492260
Hypoxia	Associate	36944699
Inflammation	Associate	36944699
Motor Disorders	Associate	35577822
Neurodegenerative Diseases	Associate	35577822
Severe Acute Respiratory Syndrome	Associate	36944699
Tricuspid Valve Insufficiency	Associate	22679008

GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)