Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	114805
Gene name	Polypeptide N-acetylgalactosaminyltransferase 13
Gene symbol	GALNT13
Synonyms (NCBI Gene)	-
Chromosome	2
Chromosome location	2q23.3
Summary	The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-ace

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miRTarBase ID	miRNA	Experiments	Reference
MIRT643959	hsa-miR-561-3p	HITS-CLIP	23824327
MIRT643958	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT643957	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT643956	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT643955	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT643954	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT643959	hsa-miR-561-3p	HITS-CLIP	23824327
MIRT643958	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT643957	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT643956	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT643955	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT643954	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT1010903	hsa-let-7a	CLIP-seq
MIRT1010904	hsa-let-7b	CLIP-seq
MIRT1010905	hsa-let-7c	CLIP-seq
MIRT1010906	hsa-let-7d	CLIP-seq
MIRT1010907	hsa-let-7e	CLIP-seq
MIRT1010908	hsa-let-7f	CLIP-seq
MIRT1010909	hsa-let-7g	CLIP-seq
MIRT1010910	hsa-let-7i	CLIP-seq
MIRT1010911	hsa-miR-196a	CLIP-seq
MIRT1010912	hsa-miR-196b	CLIP-seq
MIRT1010913	hsa-miR-203	CLIP-seq
MIRT1010914	hsa-miR-223	CLIP-seq
MIRT1010915	hsa-miR-23a	CLIP-seq
MIRT1010916	hsa-miR-23b	CLIP-seq
MIRT1010917	hsa-miR-23c	CLIP-seq
MIRT1010918	hsa-miR-3065-5p	CLIP-seq
MIRT1010919	hsa-miR-3617	CLIP-seq
MIRT1010920	hsa-miR-3662	CLIP-seq
MIRT1010921	hsa-miR-3909	CLIP-seq
MIRT1010922	hsa-miR-3920	CLIP-seq
MIRT1010923	hsa-miR-3978	CLIP-seq
MIRT1010924	hsa-miR-4274	CLIP-seq
MIRT1010925	hsa-miR-4282	CLIP-seq
MIRT1010926	hsa-miR-4421	CLIP-seq
MIRT1010927	hsa-miR-4450	CLIP-seq
MIRT1010928	hsa-miR-4458	CLIP-seq
MIRT1010929	hsa-miR-4475	CLIP-seq
MIRT1010930	hsa-miR-4500	CLIP-seq
MIRT1010931	hsa-miR-4519	CLIP-seq
MIRT1010932	hsa-miR-4677-3p	CLIP-seq
MIRT1010933	hsa-miR-4697-3p	CLIP-seq
MIRT1010934	hsa-miR-4698	CLIP-seq
MIRT1010935	hsa-miR-4765	CLIP-seq
MIRT1010936	hsa-miR-4799-5p	CLIP-seq
MIRT1010937	hsa-miR-500a	CLIP-seq
MIRT1010938	hsa-miR-501-5p	CLIP-seq
MIRT1010939	hsa-miR-509-3p	CLIP-seq
MIRT1010940	hsa-miR-5096	CLIP-seq
MIRT1010941	hsa-miR-548c-3p	CLIP-seq
MIRT1010942	hsa-miR-548p	CLIP-seq
MIRT1010943	hsa-miR-586	CLIP-seq
MIRT1010944	hsa-miR-590-3p	CLIP-seq
MIRT1010945	hsa-miR-591	CLIP-seq
MIRT1010946	hsa-miR-641	CLIP-seq
MIRT1010947	hsa-miR-656	CLIP-seq
MIRT1010948	hsa-miR-877	CLIP-seq
MIRT1010949	hsa-miR-98	CLIP-seq
MIRT1999394	hsa-miR-124	CLIP-seq
MIRT1999395	hsa-miR-3185	CLIP-seq
MIRT1999396	hsa-miR-34c-3p	CLIP-seq
MIRT1999397	hsa-miR-3611	CLIP-seq
MIRT1999398	hsa-miR-3691-3p	CLIP-seq
MIRT1999399	hsa-miR-3910	CLIP-seq
MIRT1010927	hsa-miR-4450	CLIP-seq
MIRT1999400	hsa-miR-4476	CLIP-seq
MIRT1999401	hsa-miR-4703-3p	CLIP-seq
MIRT1999402	hsa-miR-506	CLIP-seq
MIRT2233065	hsa-miR-1323	CLIP-seq
MIRT2233066	hsa-miR-4666-5p	CLIP-seq
MIRT2233067	hsa-miR-548o	CLIP-seq
MIRT1010944	hsa-miR-590-3p	CLIP-seq
MIRT2450024	hsa-miR-3143	CLIP-seq
MIRT2450025	hsa-miR-3163	CLIP-seq
MIRT2450026	hsa-miR-340	CLIP-seq
MIRT2450027	hsa-miR-3646	CLIP-seq
MIRT2450028	hsa-miR-3647-3p	CLIP-seq
MIRT1010920	hsa-miR-3662	CLIP-seq
MIRT2450029	hsa-miR-376c	CLIP-seq
MIRT1010925	hsa-miR-4282	CLIP-seq
MIRT2450030	hsa-miR-4645-3p	CLIP-seq
MIRT2450031	hsa-miR-4659a-5p	CLIP-seq
MIRT2450032	hsa-miR-4659b-5p	CLIP-seq
MIRT2450033	hsa-miR-4742-3p	CLIP-seq
MIRT2450034	hsa-miR-4776-3p	CLIP-seq
MIRT2450035	hsa-miR-4803	CLIP-seq
MIRT1010941	hsa-miR-548c-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0004653	Function	Polypeptide N-acetylgalactosaminyltransferase activity	IBA
GO:0004653	Function	Polypeptide N-acetylgalactosaminyltransferase activity	IDA	22186971
GO:0004653	Function	Polypeptide N-acetylgalactosaminyltransferase activity	IEA
GO:0004653	Function	Polypeptide N-acetylgalactosaminyltransferase activity	TAS
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IEA
GO:0006486	Process	Protein glycosylation	IEA
GO:0006493	Process	Protein O-linked glycosylation	IBA
GO:0006493	Process	Protein O-linked glycosylation	IEA
GO:0016020	Component	Membrane	IEA
GO:0016266	Process	Protein O-linked glycosylation via N-acetyl-galactosamine	IEA
GO:0016266	Process	Protein O-linked glycosylation via N-acetyl-galactosamine	TAS
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0030246	Function	Carbohydrate binding	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
608369	23242	ENSG00000144278

Q8IUC8

Protein name

Polypeptide N-acetylgalactosaminyltransferase 13 (EC 2.4.1.41) (Polypeptide GalNAc transferase 13) (GalNAc-T13) (pp-GaNTase 13) (Protein-UDP acetylgalactosaminyltransferase 13) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13)

Protein function

Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine (GalNAc) residue from UDP-GalNAc to a serine or threonine residue on the protein receptor (PubMed:12407114, PubMed:22186971). Ge

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00535	Glycos_transf_2	118 → 302	Glycosyl transferase family 2	Family
PF00652	Ricin_B_lectin	429 → 547	Ricin-type beta-trefoil lectin domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Specifically expressed in neuronal cells. Expressed in fetal brain, whole adult brain, cerebral cortex and cerebellum. Not expressed in other tissues tested. {ECO:0000269|PubMed:12407114}.

Sequence

MRRFVYCKVVLATSLMWVLVDVFLLLYFSECNKCDDKKERSLLPALRAVISRNQEGPGEM
GKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVV
IVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKNLEVPVKII
RMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVI
SDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRN
YFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHV
INKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPD
SQIPRRYYSLGEIRNVETNQCLDNMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTDDL
CLDVSRLNGPVIMLKCHHMRGNQLWEYDAERLTLRHVNSNQCLDEPSEEDKMVPTMQDCS
GSRSQQWLLRNMTLGT

Sequence length

556

Interactions

View interactions

	KEGG		Reactome
	Mucin type O-glycan biosynthesis Other types of O-glycan biosynthesis Metabolic pathways		O-linked glycosylation of mucins

GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13)