RNF157 (ring finger protein 157)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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114804 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Ring finger protein 157 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RNF157 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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Chromosome
Chromosome number
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17 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17q25.1 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q96PX1 | ||||||||||
Protein name | E3 ubiquitin ligase RNF157 (EC 2.3.2.27) (RING finger protein 157) (RING-type E3 ubiquitin transferase RNF157) | ||||||||||
Protein function | E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the proteasome and thus prevents apoptosis and promotes survival of neurons (PubMed:25342469). Has a dual role in neurons as it is also required for dendrite growth and maintena | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 679 | ||||||||||
Interactions | View interactions |