CSMD3 (CUB and Sushi multiple domains 3)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 114788
Gene name CUB and Sushi multiple domains 3
Gene symbol CSMD3
Synonyms (NCBI Gene)
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Chromosome 8
Chromosome location 8q23.3
miRNA miRNA information provided by mirtarbase database.
31
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (31)
miRTarBase ID miRNA Experiments Reference
MIRT912005 hsa-miR-1 CLIP-seq
MIRT912006 hsa-miR-1183 CLIP-seq
MIRT912007 hsa-miR-1256 CLIP-seq
MIRT912008 hsa-miR-206 CLIP-seq
MIRT912009 hsa-miR-2114 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
5
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (5)
GO ID Ontology Definition Evidence Reference
GO:0005886 Component Plasma membrane IEA
GO:0005886 Component Plasma membrane ISS
GO:0016020 Component Membrane IEA
GO:0050773 Process Regulation of dendrite development IEA
GO:0050773 Process Regulation of dendrite development ISS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
608399 19291 ENSG00000164796
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7Z407
Protein name CUB and sushi domain-containing protein 3 (CUB and sushi multiple domains protein 3)
Protein function Involved in dendrite development.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00431 CUB 65 → 170 CUB domain Domain
PF00084 Sushi 178 → 235 Sushi repeat (SCR repeat) Domain
PF00431 CUB 241 → 342 CUB domain Domain
PF00084 Sushi 486 → 543 Sushi repeat (SCR repeat) Domain
PF00431 CUB 548 → 656 CUB domain Domain
PF00084 Sushi 664 → 717 Sushi repeat (SCR repeat) Domain
PF00431 CUB 721 → 826 CUB domain Domain
PF00084 Sushi 834 → 891 Sushi repeat (SCR repeat) Domain
PF00431 CUB 895 → 1000 CUB domain Domain
PF00084 Sushi 1010 → 1063 Sushi repeat (SCR repeat) Domain
PF00431 CUB 1067 → 1174 CUB domain Domain
PF00084 Sushi 1182 → 1237 Sushi repeat (SCR repeat) Domain
PF00431 CUB 1241 → 1346 CUB domain Domain
PF00084 Sushi 1354 → 1410 Sushi repeat (SCR repeat) Domain
PF00431 CUB 1414 → 1520 CUB domain Domain
PF00084 Sushi 1528 → 1584 Sushi repeat (SCR repeat) Domain
PF00431 CUB 1588 → 1693 CUB domain Domain
PF00084 Sushi 1701 → 1758 Sushi repeat (SCR repeat) Domain
PF00431 CUB 1762 → 1867 CUB domain Domain
PF00084 Sushi 1878 → 1935 Sushi repeat (SCR repeat) Domain
PF00431 CUB 1939 → 2044 CUB domain Domain
PF00084 Sushi 2052 → 2107 Sushi repeat (SCR repeat) Domain
PF00431 CUB 2111 → 2216 CUB domain Domain
PF00084 Sushi 2224 → 2279 Sushi repeat (SCR repeat) Domain
PF00431 CUB 2283 → 2387 CUB domain Domain
PF00084 Sushi 2395 → 2452 Sushi repeat (SCR repeat) Domain
PF00431 CUB 2456 → 2564 CUB domain Domain
PF00084 Sushi 2569 → 2627 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 2632 → 2689 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 2694 → 2754 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 2759 → 2812 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 2817 → 2870 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 2875 → 2928 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 2933 → 2990 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 2995 → 3048 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 3056 → 3109 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 3114 → 3168 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 3173 → 3228 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 3233 → 3286 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 3291 → 3344 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 3352 → 3406 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 3411 → 3466 Sushi repeat (SCR repeat) Domain
Tissue specificity TISSUE SPECIFICITY: Weakly expressed in most tissues, except in brain. Expressed at intermediate level in brain, including cerebellum, substantia nigra, thalamus, spinal cord, hippocampus and fetal brain. Also expressed in testis. {ECO:0000269|PubMed:1157
Sequence 
MKGIRKGESRAKESKPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFWNLVFLLTVSCVKG
FIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS
LYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN
PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA
CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGS
EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEH
NRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLSPHPA
DTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIK
TASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHR
PVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGY
DTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIE
KESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFP
CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDG
DSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP
INARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFS
APSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSP
LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGR
RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILS
PGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSD
LPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGI
GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLN
YENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTL
SSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYG
CNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLR
CMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNI
VTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYEL
QGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITV
NADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRS
DGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLT
CIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVV
FGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITA
KGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCET
VPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQ
VVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGF
HLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRW
NYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET
IHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ
LQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE
ALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVW
DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPP
VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE
LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNI
QSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYI
ISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTN
GGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSF
ILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCG
ELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIP
ELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGS
PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPA
NSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGV
PPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPG
TPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTT
ANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPA
NGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQIS
NGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQG
KREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRH
GSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHA
NVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPA
LGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELL
LSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKD
YGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKT
QYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV
Sequence length 3707
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
94
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (16)
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Acute myeloid leukemia Benign rs61753741 RCV005935352
Adrenocortical carcinoma, hereditary Likely benign rs61753739 RCV005911962
Cervical cancer Likely benign rs61753739 RCV005911963
Cholangiocarcinoma Benign rs17652171 RCV005935173
Show/Hide Text Mining Associations (22)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma Associate 30720096
Adenocarcinoma Clear Cell Associate 37697729
Adenocarcinoma of Lung Associate 34951053, 38166691
Carcinoma Neuroendocrine Associate 34326338
Carcinoma Non Small Cell Lung Associate 40007122
Colorectal Neoplasms Associate 24408017, 24475022, 35975176
Glioblastoma Associate 34015961
Hemangioma Associate 40416971
Hemangiosarcoma Associate 37106027
Hemorrhage Associate 36264285