Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
114786
Gene name Gene Name - the full gene name approved by the HGNC.
XK related 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
XKR4
Synonyms (NCBI Gene) Gene synonyms aliases
XRG4, hXKR4
Chromosome Chromosome number
8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8q12.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT017434 hsa-miR-335-5p Microarray 18185580
MIRT629715 hsa-miR-3173-3p HITS-CLIP 23824327
MIRT629714 hsa-miR-6891-5p HITS-CLIP 23824327
MIRT629713 hsa-miR-4779 HITS-CLIP 23824327
MIRT629712 hsa-miR-4436b-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005886 Component Plasma membrane IBA 21873635
GO:0016020 Component Membrane IBA 21873635
GO:0016021 Component Integral component of membrane IEA
GO:0043652 Process Engulfment of apoptotic cell IBA 21873635
GO:0070782 Process Phosphatidylserine exposure on apoptotic cell surface IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
UniProt ID Q5GH76
Protein name XK-related protein 4 (hXKR4) [Cleaved into: XK-related protein 4, processed form]
Protein function [XK-related protein 4, processed form]: Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface (PubMed:25231987, PubMed:33725486). Phosphatidylserine is a specific marker only present at the surface of apopto
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF09815 XK-related 113 516 XK-related protein Family
Sequence
Sequence length 650
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Efferocytosis  
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Unknown
Disease term Disease name Evidence References Source
Endometriosis Endometriosis GWAS
Coronary artery disease Coronary artery disease GWAS
Metabolic Syndrome Metabolic Syndrome GWAS
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 36549768
Neoplasm Metastasis Associate 30429477
Peripheral Nervous System Diseases Associate 36549768