LACTB (lactamase beta)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 114294 |
| Gene name | Lactamase beta |
| Gene symbol | LACTB |
| Synonyms (NCBI Gene) |
G24MRPL56
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| Chromosome | 15 |
| Chromosome location | 15q22.2 |
| Summary | This gene encodes a mitochondrially-localized protein that has sequence similarity to prokaryotic beta-lactamases. Many of the residues responsible for beta-lactamase activity are not conserved in this protein, suggesting it may have a different enzymatic |
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miRNA
miRNA information provided by mirtarbase database.
339
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P83111 | |||||||||||||||
| Protein name | Serine beta-lactamase-like protein LACTB, mitochondrial (EC 3.4.-.-) | |||||||||||||||
| Protein function | Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism (PubMed:28329758). Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine ( | |||||||||||||||
| PDB | 7ULW , 7V1Y , 7V1Z , 7V21 | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed predominantly in skeletal muscle. {ECO:0000269|PubMed:11707067}. | |||||||||||||||
| Sequence |
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| Sequence length | 547 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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