LACTB (lactamase beta)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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114294 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Lactamase beta |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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LACTB |
Synonyms (NCBI Gene)
Gene synonyms aliases
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G24, MRPL56 |
Chromosome
Chromosome number
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15 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q22.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a mitochondrially-localized protein that has sequence similarity to prokaryotic beta-lactamases. Many of the residues responsible for beta-lactamase activity are not conserved in this protein, suggesting it may have a different enzymatic |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | P83111 | |||||||||||||||
Protein name | Serine beta-lactamase-like protein LACTB, mitochondrial (EC 3.4.-.-) | |||||||||||||||
Protein function | Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism (PubMed:28329758). Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine ( | |||||||||||||||
PDB | 7ULW , 7V1Y , 7V1Z , 7V21 | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed predominantly in skeletal muscle. {ECO:0000269|PubMed:11707067}. | |||||||||||||||
Sequence |
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Sequence length | 547 | |||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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