Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	114134
Gene name Gene Name - the full gene name approved by the HGNC.	Solute carrier family 2 member 13
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SLC2A13
Synonyms (NCBI Gene) Gene synonyms aliases	HMIT
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12q12

Show/Hide all(217)

miRTarBase ID	miRNA	Experiments	Reference
MIRT019106	hsa-miR-335-5p	Microarray	18185580
MIRT496282	hsa-miR-1910-3p	PAR-CLIP	22291592
MIRT496281	hsa-miR-6511a-5p	PAR-CLIP	22291592
MIRT496280	hsa-miR-6808-5p	PAR-CLIP	22291592
MIRT496279	hsa-miR-6893-5p	PAR-CLIP	22291592
MIRT496278	hsa-miR-940	PAR-CLIP	22291592
MIRT496277	hsa-miR-2682-5p	PAR-CLIP	22291592
MIRT496276	hsa-miR-34b-5p	PAR-CLIP	22291592
MIRT496275	hsa-miR-449c-5p	PAR-CLIP	22291592
MIRT496274	hsa-miR-6826-5p	PAR-CLIP	22291592
MIRT496273	hsa-miR-4705	PAR-CLIP	22291592
MIRT496272	hsa-miR-4270	PAR-CLIP	22291592
MIRT496271	hsa-miR-4441	PAR-CLIP	22291592
MIRT496270	hsa-miR-6754-5p	PAR-CLIP	22291592
MIRT496269	hsa-miR-1207-5p	PAR-CLIP	22291592
MIRT496268	hsa-miR-4763-3p	PAR-CLIP	22291592
MIRT439611	hsa-miR-381-3p	HITS-CLIP	24374217
MIRT439611	hsa-miR-381-3p	HITS-CLIP	24374217
MIRT496282	hsa-miR-1910-3p	PAR-CLIP	22291592
MIRT496281	hsa-miR-6511a-5p	PAR-CLIP	22291592
MIRT496280	hsa-miR-6808-5p	PAR-CLIP	22291592
MIRT496279	hsa-miR-6893-5p	PAR-CLIP	22291592
MIRT496278	hsa-miR-940	PAR-CLIP	22291592
MIRT496277	hsa-miR-2682-5p	PAR-CLIP	22291592
MIRT496276	hsa-miR-34b-5p	PAR-CLIP	22291592
MIRT496275	hsa-miR-449c-5p	PAR-CLIP	22291592
MIRT496274	hsa-miR-6826-5p	PAR-CLIP	22291592
MIRT496273	hsa-miR-4705	PAR-CLIP	22291592
MIRT496272	hsa-miR-4270	PAR-CLIP	22291592
MIRT496271	hsa-miR-4441	PAR-CLIP	22291592
MIRT496270	hsa-miR-6754-5p	PAR-CLIP	22291592
MIRT496269	hsa-miR-1207-5p	PAR-CLIP	22291592
MIRT496268	hsa-miR-4763-3p	PAR-CLIP	22291592
MIRT1358675	hsa-miR-1297	CLIP-seq
MIRT1358676	hsa-miR-1323	CLIP-seq
MIRT1358677	hsa-miR-136	CLIP-seq
MIRT1358678	hsa-miR-142-5p	CLIP-seq
MIRT1358679	hsa-miR-145	CLIP-seq
MIRT1358680	hsa-miR-146a	CLIP-seq
MIRT1358681	hsa-miR-146b-5p	CLIP-seq
MIRT1358682	hsa-miR-26a	CLIP-seq
MIRT1358683	hsa-miR-26b	CLIP-seq
MIRT1358684	hsa-miR-3074-3p	CLIP-seq
MIRT1358685	hsa-miR-3120-3p	CLIP-seq
MIRT1358686	hsa-miR-3140-3p	CLIP-seq
MIRT1358687	hsa-miR-3148	CLIP-seq
MIRT1358688	hsa-miR-3150b-3p	CLIP-seq
MIRT1358689	hsa-miR-323-3p	CLIP-seq
MIRT1358690	hsa-miR-34c-3p	CLIP-seq
MIRT1358691	hsa-miR-3682-5p	CLIP-seq
MIRT1358692	hsa-miR-371-5p	CLIP-seq
MIRT1358693	hsa-miR-371b-5p	CLIP-seq
MIRT1358694	hsa-miR-384	CLIP-seq
MIRT1358695	hsa-miR-3915	CLIP-seq
MIRT1358696	hsa-miR-3928	CLIP-seq
MIRT1358697	hsa-miR-3944-5p	CLIP-seq
MIRT1358698	hsa-miR-409-3p	CLIP-seq
MIRT1358699	hsa-miR-4279	CLIP-seq
MIRT1358700	hsa-miR-4282	CLIP-seq
MIRT1358701	hsa-miR-4303	CLIP-seq
MIRT1358702	hsa-miR-4318	CLIP-seq
MIRT1358703	hsa-miR-4465	CLIP-seq
MIRT1358704	hsa-miR-4474-3p	CLIP-seq
MIRT1358705	hsa-miR-4649-3p	CLIP-seq
MIRT1358706	hsa-miR-4662a-3p	CLIP-seq
MIRT1358707	hsa-miR-4666-5p	CLIP-seq
MIRT1358708	hsa-miR-4686	CLIP-seq
MIRT1358709	hsa-miR-4691-5p	CLIP-seq
MIRT1358710	hsa-miR-4724-3p	CLIP-seq
MIRT1358711	hsa-miR-4762-3p	CLIP-seq
MIRT1358712	hsa-miR-4777-5p	CLIP-seq
MIRT1358713	hsa-miR-4784	CLIP-seq
MIRT1358714	hsa-miR-4795-3p	CLIP-seq
MIRT1358715	hsa-miR-513a-3p	CLIP-seq
MIRT1358716	hsa-miR-513c	CLIP-seq
MIRT1358717	hsa-miR-514b-5p	CLIP-seq
MIRT1358718	hsa-miR-518d-5p	CLIP-seq
MIRT1358719	hsa-miR-519b-5p	CLIP-seq
MIRT1358720	hsa-miR-519c-5p	CLIP-seq
MIRT1358721	hsa-miR-520c-5p	CLIP-seq
MIRT1358722	hsa-miR-526a	CLIP-seq
MIRT1358723	hsa-miR-545	CLIP-seq
MIRT1358724	hsa-miR-548c-3p	CLIP-seq
MIRT1358725	hsa-miR-548o	CLIP-seq
MIRT1358726	hsa-miR-548p	CLIP-seq
MIRT1358727	hsa-miR-630	CLIP-seq
MIRT1358728	hsa-miR-648	CLIP-seq
MIRT1358729	hsa-miR-765	CLIP-seq
MIRT2106224	hsa-miR-150	CLIP-seq
MIRT2106225	hsa-miR-3185	CLIP-seq
MIRT2106226	hsa-miR-3200-5p	CLIP-seq
MIRT2106227	hsa-miR-383	CLIP-seq
MIRT1358702	hsa-miR-4318	CLIP-seq
MIRT2106228	hsa-miR-4511	CLIP-seq
MIRT1358714	hsa-miR-4795-3p	CLIP-seq
MIRT2330536	hsa-miR-1225-5p	CLIP-seq
MIRT2330537	hsa-miR-151-3p	CLIP-seq
MIRT2330538	hsa-miR-193a-3p	CLIP-seq
MIRT2330539	hsa-miR-193b	CLIP-seq
MIRT2330540	hsa-miR-221	CLIP-seq
MIRT2330541	hsa-miR-222	CLIP-seq
MIRT2330542	hsa-miR-224	CLIP-seq
MIRT2330543	hsa-miR-331-3p	CLIP-seq
MIRT2330544	hsa-miR-338-5p	CLIP-seq
MIRT2330545	hsa-miR-3617	CLIP-seq
MIRT2330546	hsa-miR-3682-3p	CLIP-seq
MIRT2330547	hsa-miR-4252	CLIP-seq
MIRT1358702	hsa-miR-4318	CLIP-seq
MIRT2330548	hsa-miR-4463	CLIP-seq
MIRT2330549	hsa-miR-4499	CLIP-seq
MIRT2330550	hsa-miR-4682	CLIP-seq
MIRT2330551	hsa-miR-4690-3p	CLIP-seq
MIRT2330552	hsa-miR-4693-5p	CLIP-seq
MIRT2330553	hsa-miR-4711-5p	CLIP-seq
MIRT2330554	hsa-miR-548v	CLIP-seq
MIRT2330555	hsa-miR-568	CLIP-seq
MIRT2330556	hsa-miR-641	CLIP-seq
MIRT2330557	hsa-miR-642b	CLIP-seq
MIRT2330558	hsa-miR-646	CLIP-seq
MIRT2330559	hsa-miR-664	CLIP-seq
MIRT2330560	hsa-miR-892a	CLIP-seq
MIRT2330540	hsa-miR-221	CLIP-seq
MIRT2330541	hsa-miR-222	CLIP-seq
MIRT2330558	hsa-miR-646	CLIP-seq
MIRT2394712	hsa-miR-885-3p	CLIP-seq
MIRT2440458	hsa-miR-1237	CLIP-seq
MIRT2440459	hsa-miR-1248	CLIP-seq
MIRT1358700	hsa-miR-4282	CLIP-seq
MIRT2440460	hsa-miR-4684-5p	CLIP-seq
MIRT1358715	hsa-miR-513a-3p	CLIP-seq
MIRT2440461	hsa-miR-942	CLIP-seq
MIRT2330542	hsa-miR-224	CLIP-seq
MIRT2440458	hsa-miR-1237	CLIP-seq
MIRT2624588	hsa-miR-1245b-3p	CLIP-seq
MIRT2440459	hsa-miR-1248	CLIP-seq
MIRT2624589	hsa-miR-1257	CLIP-seq
MIRT2624590	hsa-miR-1264	CLIP-seq
MIRT2624591	hsa-miR-1265	CLIP-seq
MIRT2624592	hsa-miR-1276	CLIP-seq
MIRT2624593	hsa-miR-1343	CLIP-seq
MIRT2624594	hsa-miR-181a	CLIP-seq
MIRT2624595	hsa-miR-181b	CLIP-seq
MIRT2624596	hsa-miR-181c	CLIP-seq
MIRT2624597	hsa-miR-181d	CLIP-seq
MIRT2624598	hsa-miR-203	CLIP-seq
MIRT2330540	hsa-miR-221	CLIP-seq
MIRT2330541	hsa-miR-222	CLIP-seq
MIRT2624599	hsa-miR-23a	CLIP-seq
MIRT2624600	hsa-miR-23b	CLIP-seq
MIRT2624601	hsa-miR-23c	CLIP-seq
MIRT2624602	hsa-miR-300	CLIP-seq
MIRT2624603	hsa-miR-3074-5p	CLIP-seq
MIRT2624604	hsa-miR-3119	CLIP-seq
MIRT2624605	hsa-miR-3157-5p	CLIP-seq
MIRT1358689	hsa-miR-323-3p	CLIP-seq
MIRT2624606	hsa-miR-3614-3p	CLIP-seq
MIRT2624607	hsa-miR-3646	CLIP-seq
MIRT2624608	hsa-miR-3653	CLIP-seq
MIRT2624609	hsa-miR-3658	CLIP-seq
MIRT2624610	hsa-miR-3690	CLIP-seq
MIRT2624611	hsa-miR-381	CLIP-seq
MIRT2624612	hsa-miR-3913-3p	CLIP-seq
MIRT2624613	hsa-miR-4254	CLIP-seq
MIRT2624614	hsa-miR-4262	CLIP-seq
MIRT1358700	hsa-miR-4282	CLIP-seq
MIRT1358701	hsa-miR-4303	CLIP-seq
MIRT2624615	hsa-miR-4311	CLIP-seq
MIRT2624616	hsa-miR-4493	CLIP-seq
MIRT2624617	hsa-miR-4495	CLIP-seq
MIRT2624618	hsa-miR-4509	CLIP-seq
MIRT2624619	hsa-miR-451b	CLIP-seq
MIRT2624620	hsa-miR-4643	CLIP-seq
MIRT2440460	hsa-miR-4684-5p	CLIP-seq
MIRT2330551	hsa-miR-4690-3p	CLIP-seq
MIRT2624621	hsa-miR-4729	CLIP-seq
MIRT2624622	hsa-miR-4744	CLIP-seq
MIRT2624623	hsa-miR-489	CLIP-seq
MIRT2624624	hsa-miR-499-3p	CLIP-seq
MIRT2624625	hsa-miR-499a-3p	CLIP-seq
MIRT1358715	hsa-miR-513a-3p	CLIP-seq
MIRT1358724	hsa-miR-548c-3p	CLIP-seq
MIRT2330554	hsa-miR-548v	CLIP-seq
MIRT2624626	hsa-miR-570	CLIP-seq
MIRT2624627	hsa-miR-579	CLIP-seq
MIRT2624628	hsa-miR-583	CLIP-seq
MIRT2394712	hsa-miR-885-3p	CLIP-seq
MIRT2440461	hsa-miR-942	CLIP-seq
MIRT2440458	hsa-miR-1237	CLIP-seq
MIRT2440459	hsa-miR-1248	CLIP-seq
MIRT2624589	hsa-miR-1257	CLIP-seq
MIRT2624591	hsa-miR-1265	CLIP-seq
MIRT2624592	hsa-miR-1276	CLIP-seq
MIRT2624593	hsa-miR-1343	CLIP-seq
MIRT2624602	hsa-miR-300	CLIP-seq
MIRT2624603	hsa-miR-3074-5p	CLIP-seq
MIRT2624606	hsa-miR-3614-3p	CLIP-seq
MIRT2624610	hsa-miR-3690	CLIP-seq
MIRT2624611	hsa-miR-381	CLIP-seq
MIRT2624613	hsa-miR-4254	CLIP-seq
MIRT1358700	hsa-miR-4282	CLIP-seq
MIRT1358701	hsa-miR-4303	CLIP-seq
MIRT2624615	hsa-miR-4311	CLIP-seq
MIRT2624617	hsa-miR-4495	CLIP-seq
MIRT2624618	hsa-miR-4509	CLIP-seq
MIRT2624619	hsa-miR-451b	CLIP-seq
MIRT2624620	hsa-miR-4643	CLIP-seq
MIRT2440460	hsa-miR-4684-5p	CLIP-seq
MIRT2624621	hsa-miR-4729	CLIP-seq
MIRT2624622	hsa-miR-4744	CLIP-seq
MIRT1358715	hsa-miR-513a-3p	CLIP-seq
MIRT1358724	hsa-miR-548c-3p	CLIP-seq
MIRT2624626	hsa-miR-570	CLIP-seq
MIRT2624627	hsa-miR-579	CLIP-seq
MIRT2624628	hsa-miR-583	CLIP-seq
MIRT2330558	hsa-miR-646	CLIP-seq
MIRT2394712	hsa-miR-885-3p	CLIP-seq
MIRT2440461	hsa-miR-942	CLIP-seq

Show/Hide all(47)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002020	Function	Protease binding	IEA
GO:0002020	Function	Protease binding	IPI	26094765
GO:0002020	Function	Protease binding	ISS	26094765
GO:0005365	Function	Myo-inositol transmembrane transporter activity	IEA
GO:0005365	Function	Myo-inositol transmembrane transporter activity	ISS
GO:0005366	Function	Myo-inositol:proton symporter activity	IBA
GO:0005366	Function	Myo-inositol:proton symporter activity	IDA	11500374
GO:0005366	Function	Myo-inositol:proton symporter activity	TAS
GO:0005515	Function	Protein binding	IPI	32296183, 32814053
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS	19607714
GO:0005764	Component	Lysosome	ISS
GO:0005769	Component	Early endosome	ISS
GO:0005794	Component	Golgi apparatus	ISS	19607714
GO:0005886	Component	Plasma membrane	IDA	11500374
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0008021	Component	Synaptic vesicle	ISS
GO:0015798	Process	Myo-inositol transport	IBA
GO:0015798	Process	Myo-inositol transport	IDA	11500374
GO:0015798	Process	Myo-inositol transport	IEA
GO:0015798	Process	Myo-inositol transport	ISS
GO:0015798	Process	Myo-inositol transport	TAS
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	ISS
GO:0016324	Component	Apical plasma membrane	IBA
GO:0022857	Function	Transmembrane transporter activity	IEA
GO:0030426	Component	Growth cone	IEA
GO:0030426	Component	Growth cone	ISS
GO:0031090	Component	Organelle membrane	IEA
GO:0031090	Component	Organelle membrane	ISS
GO:0042995	Component	Cell projection	IDA	19607714
GO:0042995	Component	Cell projection	IEA
GO:0043231	Component	Intracellular membrane-bounded organelle	IEA
GO:0044297	Component	Cell body	IDA	19607714
GO:0044297	Component	Cell body	IEA
GO:0044297	Component	Cell body	ISS
GO:0051117	Function	ATPase binding	IPI	26094765
GO:0055085	Process	Transmembrane transport	IBA
GO:0055085	Process	Transmembrane transport	IEA
GO:0071944	Component	Cell periphery	IDA	19607714
GO:0071944	Component	Cell periphery	IEA
GO:0071944	Component	Cell periphery	ISS	11500374
GO:0097450	Component	Astrocyte end-foot	IEA
GO:0097450	Component	Astrocyte end-foot	ISS	11500374
GO:0150104	Process	Transport across blood-brain barrier	NAS	26590417, 30280653
GO:1902004	Process	Positive regulation of amyloid-beta formation	IGI	26094765

MIM	HGNC	e!Ensembl
611036	15956	ENSG00000151229

Protein

UniProt ID

Q96QE2

Protein name

Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13)

Protein function

H(+)-myo-inositol cotransporter (PubMed:11500374). Can also transport related stereoisomers (PubMed:11500374).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00083	Sugar_tr	84 → 425	Sugar (and other) transporter	Family
PF00083	Sugar_tr	497 → 609	Sugar (and other) transporter	Family

Tissue specificity

TISSUE SPECIFICITY: Predominantly expressed in the brain. {ECO:0000269|PubMed:11500374}.

Sequence

MSRKASENVEYTLRSLSSLMGERRRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGG
VGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQ
ELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLV
VGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRY
MLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIE
EEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDD
RLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSP
RITFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAW
GRCENETKFKTEDIFWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWA
RSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGK
KLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVKGSNYHLSDNDASDVE

Sequence length

648

Interactions

View interactions

	Reactome
			Inositol transporters

Show/Hide Unknown Diseases (6)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Colorectal Cancer	Overall survival in colorectal cancer	N/A	N/A	GWAS
Crohn Disease	Crohn's disease	N/A	N/A	GWAS
Inflammatory Bowel Disease	Inflammatory bowel disease (MTAG), Inflammatory bowel disease	N/A	N/A	GWAS
Insomnia	Insomnia	N/A	N/A	GWAS
Leprosy	Leprosy	N/A	N/A	GWAS
Ulcerative colitis	Ulcerative colitis	N/A	N/A	GWAS

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Dental Plaque	Associate	29482039
Leukemia Myeloid Acute	Associate	31918632
Pancreatic Neoplasms	Associate	30972876
Parkinson Disease	Associate	22763023, 33341150
Squamous Cell Carcinoma of Head and Neck	Stimulate	37542344
Supranuclear Palsy Progressive	Associate	33341150, 35384155, 39260141

SLC2A13 (solute carrier family 2 member 13)