Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
113263
Gene name Gene Name - the full gene name approved by the HGNC.
Glucocorticoid induced 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GLCCI1
Synonyms (NCBI Gene) Gene synonyms aliases
FAM117C, GCTR, GIG18, TSSN1
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7p21.3
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a protein of unknown function. Expression of this gene is induced by glucocorticoids and may be an early marker for glucocorticoid-induced apoptosis. Single nucleotide polymorphisms in this gene are associated with a decreased response t
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT017656 hsa-miR-335-5p Microarray 18185580
MIRT026406 hsa-miR-192-5p Microarray 19074876
MIRT002411 hsa-miR-21-5p Sequencing 20371350
MIRT002411 hsa-miR-21-5p Microarray 18591254
MIRT612230 hsa-miR-8485 HITS-CLIP 22927820
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005737 Component Cytoplasm IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
614283 18713 ENSG00000106415
Protein
UniProt ID Q86VQ1
Protein name Glucocorticoid-induced transcript 1 protein
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15388 FAM117 167 477 Protein Family FAM117 Family
Tissue specificity TISSUE SPECIFICITY: Predominantly expressed in lung, spleen, thymus and testis and, at lower levels, in brain, bone marrow, peripheral leukocytes, skin and trachea. {ECO:0000269|PubMed:12557054, ECO:0000269|PubMed:21991891}.
Sequence
MSTASSSSSSSSSQTPHPPSQRMRRSAAGSPPAVAAAGSGNGAGGGGGVGCAPAAGAGRL
LQPIRATVPYQLLRGSQHSPTRPPVAAAAASLGSLPGPGAARGPSPSSPTPPAAAAPAEQ
APRAKGRPRRSPESHRRSSSPERRSPGSPVCRADKAKSQQVRTSSTIRRTSSLDTITGPY
LTGQWPRDPHVHYPSCMKDKATQTPSCWAEEGAEKRSHQRSASWGSADQLKEQIAKLRQQ
LQRSKQSSRHSKEKDRQSPLHGNHITISHTQATGSRSVPMPLSNISVPKSSVSRVPCNVE
GISPELEKVFIKENNGKEEVSKPLDIPDGRRAPLPAHYRSSSTRSIDTQTPSVQERSSSC
SSHSPCVSPFCPPESQDGSPCSTEDLLYDRDKDSGSSSPLPKYASSPKPNNSYMFKREPP
EGCERVKVFEEMASRQPISAPLFSCPDKNKVNFIPTGSAFCPVKLLGPLLPASDLML
KNS
PNSGQSSALATLTVEQLSSRVSFTSLSDDTSTAGSMEASVQQPSQQQQLLQELQGEDHIS
AQNYVII
Sequence length 547
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Unknown
Disease term Disease name Evidence References Source
Coronary heart disease Coronary heart disease 28753643 ClinVar
Coronary syndrome Acute Coronary Syndrome 28753643 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma Associate 23301059
Adenoma Associate 23301059
Arthritis Rheumatoid Associate 25724472
Asthma Associate 21991891, 27852250, 29224020, 29345236, 29384926, 31391381
Behcet Syndrome Associate 39278467
Bipolar and Related Disorders Associate 39278467
Bipolar Disorder Associate 39278467
Carcinogenesis Associate 23301059
Glaucoma Associate 23836780
Glaucoma Open Angle Associate 23836780