Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
113251
Gene name Gene Name - the full gene name approved by the HGNC.
La ribonucleoprotein 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
LARP4
Synonyms (NCBI Gene) Gene synonyms aliases
PP13296
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q13.12
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT003525 hsa-miR-1-3p Luciferase reporter assay 20144220
MIRT028536 hsa-miR-30a-5p Proteomics 18668040
MIRT031626 hsa-miR-16-5p Proteomics 18668040
MIRT043579 hsa-miR-148b-3p CLASH 23622248
MIRT042545 hsa-miR-423-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003730 Function MRNA 3'-UTR binding IDA 26001795
GO:0005515 Function Protein binding IPI 21098120, 26496610, 29513927, 30021884, 31046837
GO:0005829 Component Cytosol IDA 21098120
GO:0005844 Component Polysome IDA 21098120
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
618657 24320 ENSG00000161813
Protein
UniProt ID Q71RC2
Protein name La-related protein 4 (La ribonucleoprotein domain family member 4)
Protein function RNA binding protein that binds to the poly-A tract of mRNA molecules (PubMed:21098120). Associates with the 40S ribosomal subunit and with polysomes (PubMed:21098120). Plays a role in the regulation of mRNA translation (PubMed:21098120). Plays a
PDB 2CQK , 3PKN , 6I9B
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05383 La 123 179 La domain Domain
Sequence
MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAEL
SEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLK
ECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSS
PMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYI
TFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINTFFAKNGYRLMDSSIYSHPIQTQAQ
YASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPNGSFVNGFNSPGSYKTN
AAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHNPTVTGH
QEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPTPKFDLL
ASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTECTSAQQL
NMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPPSTTKPSRASTASPCN
NNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELRSNVVSPTKNEDNGAPENS
VEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQFSHRAIPQGVTRRNGKEQYVPP
RSPK
Sequence length 724
Interactions View interactions