Gene Gene information from NCBI Gene database.
Entrez ID 113251
Gene name La ribonucleoprotein 4
Gene symbol LARP4
Synonyms (NCBI Gene)
PP13296
Chromosome 12
Chromosome location 12q13.12
miRNA miRNA information provided by mirtarbase database.
689
miRTarBase ID miRNA Experiments Reference
MIRT003525 hsa-miR-1-3p Luciferase reporter assay 20144220
MIRT028536 hsa-miR-30a-5p Proteomics 18668040
MIRT031626 hsa-miR-16-5p Proteomics 18668040
MIRT043579 hsa-miR-148b-3p CLASH 23622248
MIRT042545 hsa-miR-423-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
GO ID Ontology Definition Evidence Reference
GO:0003676 Function Nucleic acid binding IEA
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003723 Function RNA binding IEA
GO:0003730 Function MRNA 3'-UTR binding IBA
GO:0003730 Function MRNA 3'-UTR binding IDA 26001795
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
618657 24320 ENSG00000161813
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q71RC2
Protein name La-related protein 4 (La ribonucleoprotein domain family member 4)
Protein function RNA binding protein that binds to the poly-A tract of mRNA molecules (PubMed:21098120). Associates with the 40S ribosomal subunit and with polysomes (PubMed:21098120). Plays a role in the regulation of mRNA translation (PubMed:21098120). Plays a
PDB 2CQK , 3PKN , 6I9B
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05383 La 123 179 La domain Domain
Sequence
MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAEL
SEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLK
ECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSS
PMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYI
TFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINTFFAKNGYRLMDSSIYSHPIQTQAQ
YASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPNGSFVNGFNSPGSYKTN
AAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHNPTVTGH
QEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPTPKFDLL
ASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTECTSAQQL
NMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPPSTTKPSRASTASPCN
NNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELRSNVVSPTKNEDNGAPENS
VEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQFSHRAIPQGVTRRNGKEQYVPP
RSPK
Sequence length 724
Interactions View interactions