Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	113130
Gene name Gene Name - the full gene name approved by the HGNC.	Cell division cycle associated 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CDCA5
Synonyms (NCBI Gene) Gene synonyms aliases	SORORIN
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11q13.1

Show/Hide all(221)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016488	hsa-miR-193b-3p	Microarray	20304954
MIRT050732	hsa-miR-18a-5p	CLASH	23622248
MIRT042416	hsa-miR-18b-5p	CLASH	23622248
MIRT878939	hsa-miR-1197	CLIP-seq
MIRT878940	hsa-miR-1224-5p	CLIP-seq
MIRT878941	hsa-miR-1231	CLIP-seq
MIRT878942	hsa-miR-1236	CLIP-seq
MIRT878943	hsa-miR-1296	CLIP-seq
MIRT878944	hsa-miR-1321	CLIP-seq
MIRT878945	hsa-miR-148a	CLIP-seq
MIRT878946	hsa-miR-148b	CLIP-seq
MIRT878947	hsa-miR-152	CLIP-seq
MIRT878948	hsa-miR-1909	CLIP-seq
MIRT878949	hsa-miR-2110	CLIP-seq
MIRT878950	hsa-miR-214	CLIP-seq
MIRT878951	hsa-miR-2355-5p	CLIP-seq
MIRT878952	hsa-miR-302f	CLIP-seq
MIRT878953	hsa-miR-3120-5p	CLIP-seq
MIRT878954	hsa-miR-3144-5p	CLIP-seq
MIRT878955	hsa-miR-3150a-3p	CLIP-seq
MIRT878956	hsa-miR-3175	CLIP-seq
MIRT878957	hsa-miR-3183	CLIP-seq
MIRT878958	hsa-miR-3192	CLIP-seq
MIRT878959	hsa-miR-3199	CLIP-seq
MIRT878960	hsa-miR-326	CLIP-seq
MIRT878961	hsa-miR-330-5p	CLIP-seq
MIRT878962	hsa-miR-3619-5p	CLIP-seq
MIRT878963	hsa-miR-3689d	CLIP-seq
MIRT878964	hsa-miR-3909	CLIP-seq
MIRT878965	hsa-miR-3943	CLIP-seq
MIRT878966	hsa-miR-411	CLIP-seq
MIRT878967	hsa-miR-4260	CLIP-seq
MIRT878968	hsa-miR-4270	CLIP-seq
MIRT878969	hsa-miR-4276	CLIP-seq
MIRT878970	hsa-miR-4282	CLIP-seq
MIRT878971	hsa-miR-4314	CLIP-seq
MIRT878972	hsa-miR-4436a	CLIP-seq
MIRT878973	hsa-miR-4441	CLIP-seq
MIRT878974	hsa-miR-4459	CLIP-seq
MIRT878975	hsa-miR-4468	CLIP-seq
MIRT878976	hsa-miR-4476	CLIP-seq
MIRT878977	hsa-miR-4480	CLIP-seq
MIRT878978	hsa-miR-4490	CLIP-seq
MIRT878979	hsa-miR-4496	CLIP-seq
MIRT878980	hsa-miR-4512	CLIP-seq
MIRT878981	hsa-miR-4530	CLIP-seq
MIRT878982	hsa-miR-4533	CLIP-seq
MIRT878983	hsa-miR-4646-5p	CLIP-seq
MIRT878984	hsa-miR-4690-3p	CLIP-seq
MIRT878985	hsa-miR-4699-3p	CLIP-seq
MIRT878986	hsa-miR-4700-3p	CLIP-seq
MIRT878987	hsa-miR-4723-3p	CLIP-seq
MIRT878988	hsa-miR-4728-5p	CLIP-seq
MIRT878989	hsa-miR-4739	CLIP-seq
MIRT878990	hsa-miR-4751	CLIP-seq
MIRT878991	hsa-miR-4753-3p	CLIP-seq
MIRT878992	hsa-miR-4756-5p	CLIP-seq
MIRT878993	hsa-miR-4768-5p	CLIP-seq
MIRT878994	hsa-miR-4774-5p	CLIP-seq
MIRT878995	hsa-miR-548ae	CLIP-seq
MIRT878996	hsa-miR-548aj	CLIP-seq
MIRT878997	hsa-miR-548am	CLIP-seq
MIRT878998	hsa-miR-548x	CLIP-seq
MIRT878999	hsa-miR-595	CLIP-seq
MIRT879000	hsa-miR-626	CLIP-seq
MIRT879001	hsa-miR-645	CLIP-seq
MIRT879002	hsa-miR-661	CLIP-seq
MIRT879003	hsa-miR-761	CLIP-seq
MIRT879004	hsa-miR-939	CLIP-seq
MIRT878939	hsa-miR-1197	CLIP-seq
MIRT1960551	hsa-miR-1226	CLIP-seq
MIRT878941	hsa-miR-1231	CLIP-seq
MIRT1960552	hsa-miR-1256	CLIP-seq
MIRT1960553	hsa-miR-1273f	CLIP-seq
MIRT878944	hsa-miR-1321	CLIP-seq
MIRT1960554	hsa-miR-143	CLIP-seq
MIRT878945	hsa-miR-148a	CLIP-seq
MIRT878946	hsa-miR-148b	CLIP-seq
MIRT878947	hsa-miR-152	CLIP-seq
MIRT878948	hsa-miR-1909	CLIP-seq
MIRT1960555	hsa-miR-198	CLIP-seq
MIRT1960556	hsa-miR-203	CLIP-seq
MIRT878950	hsa-miR-214	CLIP-seq
MIRT878951	hsa-miR-2355-5p	CLIP-seq
MIRT1960557	hsa-miR-2467-3p	CLIP-seq
MIRT1960558	hsa-miR-2964a-3p	CLIP-seq
MIRT1960559	hsa-miR-29a	CLIP-seq
MIRT1960560	hsa-miR-29b	CLIP-seq
MIRT1960561	hsa-miR-29c	CLIP-seq
MIRT1960562	hsa-miR-3065-3p	CLIP-seq
MIRT878953	hsa-miR-3120-5p	CLIP-seq
MIRT878954	hsa-miR-3144-5p	CLIP-seq
MIRT1960563	hsa-miR-3155	CLIP-seq
MIRT1960564	hsa-miR-3155b	CLIP-seq
MIRT1960565	hsa-miR-3157-3p	CLIP-seq
MIRT878958	hsa-miR-3192	CLIP-seq
MIRT878959	hsa-miR-3199	CLIP-seq
MIRT878960	hsa-miR-326	CLIP-seq
MIRT878961	hsa-miR-330-5p	CLIP-seq
MIRT878962	hsa-miR-3619-5p	CLIP-seq
MIRT1960566	hsa-miR-3661	CLIP-seq
MIRT1960567	hsa-miR-3925-3p	CLIP-seq
MIRT878965	hsa-miR-3943	CLIP-seq
MIRT1960568	hsa-miR-4267	CLIP-seq
MIRT878969	hsa-miR-4276	CLIP-seq
MIRT1960569	hsa-miR-4290	CLIP-seq
MIRT878971	hsa-miR-4314	CLIP-seq
MIRT878975	hsa-miR-4468	CLIP-seq
MIRT1960570	hsa-miR-4505	CLIP-seq
MIRT878981	hsa-miR-4530	CLIP-seq
MIRT1960571	hsa-miR-4640-5p	CLIP-seq
MIRT878983	hsa-miR-4646-5p	CLIP-seq
MIRT878984	hsa-miR-4690-3p	CLIP-seq
MIRT1960572	hsa-miR-4691-5p	CLIP-seq
MIRT878985	hsa-miR-4699-3p	CLIP-seq
MIRT1960573	hsa-miR-4708-5p	CLIP-seq
MIRT1960574	hsa-miR-4720-5p	CLIP-seq
MIRT1960575	hsa-miR-4726-5p	CLIP-seq
MIRT878988	hsa-miR-4728-5p	CLIP-seq
MIRT878989	hsa-miR-4739	CLIP-seq
MIRT1960576	hsa-miR-4755-3p	CLIP-seq
MIRT1960577	hsa-miR-4756-3p	CLIP-seq
MIRT878992	hsa-miR-4756-5p	CLIP-seq
MIRT878993	hsa-miR-4768-5p	CLIP-seq
MIRT1960578	hsa-miR-4770	CLIP-seq
MIRT1960579	hsa-miR-4778-3p	CLIP-seq
MIRT1960580	hsa-miR-4799-3p	CLIP-seq
MIRT1960581	hsa-miR-484	CLIP-seq
MIRT1960582	hsa-miR-515-5p	CLIP-seq
MIRT1960583	hsa-miR-520a-5p	CLIP-seq
MIRT1960584	hsa-miR-525-5p	CLIP-seq
MIRT878999	hsa-miR-595	CLIP-seq
MIRT1960585	hsa-miR-618	CLIP-seq
MIRT879000	hsa-miR-626	CLIP-seq
MIRT1960586	hsa-miR-631	CLIP-seq
MIRT1960587	hsa-miR-634	CLIP-seq
MIRT879001	hsa-miR-645	CLIP-seq
MIRT879003	hsa-miR-761	CLIP-seq
MIRT1960588	hsa-miR-766	CLIP-seq
MIRT1960589	hsa-miR-874	CLIP-seq
MIRT2197254	hsa-miR-10a	CLIP-seq
MIRT2197255	hsa-miR-10b	CLIP-seq
MIRT878939	hsa-miR-1197	CLIP-seq
MIRT878940	hsa-miR-1224-5p	CLIP-seq
MIRT1960551	hsa-miR-1226	CLIP-seq
MIRT1960552	hsa-miR-1256	CLIP-seq
MIRT878943	hsa-miR-1296	CLIP-seq
MIRT878945	hsa-miR-148a	CLIP-seq
MIRT878946	hsa-miR-148b	CLIP-seq
MIRT878947	hsa-miR-152	CLIP-seq
MIRT2197256	hsa-miR-1910	CLIP-seq
MIRT878949	hsa-miR-2110	CLIP-seq
MIRT878950	hsa-miR-214	CLIP-seq
MIRT878951	hsa-miR-2355-5p	CLIP-seq
MIRT2197257	hsa-miR-2909	CLIP-seq
MIRT1960559	hsa-miR-29a	CLIP-seq
MIRT1960560	hsa-miR-29b	CLIP-seq
MIRT1960561	hsa-miR-29c	CLIP-seq
MIRT1960562	hsa-miR-3065-3p	CLIP-seq
MIRT2197258	hsa-miR-3119	CLIP-seq
MIRT2197259	hsa-miR-3130-3p	CLIP-seq
MIRT878954	hsa-miR-3144-5p	CLIP-seq
MIRT878955	hsa-miR-3150a-3p	CLIP-seq
MIRT1960563	hsa-miR-3155	CLIP-seq
MIRT1960564	hsa-miR-3155b	CLIP-seq
MIRT2197260	hsa-miR-3157-5p	CLIP-seq
MIRT878956	hsa-miR-3175	CLIP-seq
MIRT2197261	hsa-miR-3176	CLIP-seq
MIRT878962	hsa-miR-3619-5p	CLIP-seq
MIRT2197262	hsa-miR-3691-3p	CLIP-seq
MIRT2197263	hsa-miR-3922-3p	CLIP-seq
MIRT2197264	hsa-miR-421	CLIP-seq
MIRT878967	hsa-miR-4260	CLIP-seq
MIRT878969	hsa-miR-4276	CLIP-seq
MIRT2197265	hsa-miR-4419a	CLIP-seq
MIRT2197266	hsa-miR-4435	CLIP-seq
MIRT878972	hsa-miR-4436a	CLIP-seq
MIRT878974	hsa-miR-4459	CLIP-seq
MIRT2197267	hsa-miR-4510	CLIP-seq
MIRT878980	hsa-miR-4512	CLIP-seq
MIRT878981	hsa-miR-4530	CLIP-seq
MIRT2197268	hsa-miR-4676-5p	CLIP-seq
MIRT2197269	hsa-miR-4691-3p	CLIP-seq
MIRT878986	hsa-miR-4700-3p	CLIP-seq
MIRT2197270	hsa-miR-4707-3p	CLIP-seq
MIRT2197271	hsa-miR-4709-5p	CLIP-seq
MIRT2197272	hsa-miR-4711-5p	CLIP-seq
MIRT2197273	hsa-miR-4714-3p	CLIP-seq
MIRT1960574	hsa-miR-4720-5p	CLIP-seq
MIRT878988	hsa-miR-4728-5p	CLIP-seq
MIRT2197274	hsa-miR-4732-3p	CLIP-seq
MIRT2197275	hsa-miR-4738-5p	CLIP-seq
MIRT878990	hsa-miR-4751	CLIP-seq
MIRT2197276	hsa-miR-4779	CLIP-seq
MIRT1960580	hsa-miR-4799-3p	CLIP-seq
MIRT1960581	hsa-miR-484	CLIP-seq
MIRT2197277	hsa-miR-490-3p	CLIP-seq
MIRT2197278	hsa-miR-575	CLIP-seq
MIRT878999	hsa-miR-595	CLIP-seq
MIRT1960585	hsa-miR-618	CLIP-seq
MIRT1960587	hsa-miR-634	CLIP-seq
MIRT879001	hsa-miR-645	CLIP-seq
MIRT879003	hsa-miR-761	CLIP-seq
MIRT2197279	hsa-miR-922	CLIP-seq
MIRT879004	hsa-miR-939	CLIP-seq
MIRT1960562	hsa-miR-3065-3p	CLIP-seq
MIRT2197259	hsa-miR-3130-3p	CLIP-seq
MIRT2197261	hsa-miR-3176	CLIP-seq
MIRT2197263	hsa-miR-3922-3p	CLIP-seq
MIRT2197269	hsa-miR-4691-3p	CLIP-seq
MIRT2197270	hsa-miR-4707-3p	CLIP-seq
MIRT2446660	hsa-miR-103a	CLIP-seq
MIRT2446661	hsa-miR-107	CLIP-seq
MIRT2446662	hsa-miR-1184	CLIP-seq
MIRT2446663	hsa-miR-759	CLIP-seq
MIRT2197279	hsa-miR-922	CLIP-seq
MIRT2446660	hsa-miR-103a	CLIP-seq
MIRT2446661	hsa-miR-107	CLIP-seq
MIRT2446662	hsa-miR-1184	CLIP-seq
MIRT2446663	hsa-miR-759	CLIP-seq
MIRT2197279	hsa-miR-922	CLIP-seq

Show/Hide all(23)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000775	Component	Chromosome, centromeric region	TAS
GO:0000785	Component	Chromatin	IEA
GO:0000785	Component	Chromatin	ISS
GO:0003682	Function	Chromatin binding	TAS	15837422
GO:0005515	Function	Protein binding	IPI	21111234, 22885700, 23242214, 26496610, 32296183, 33961781, 35271311
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005694	Component	Chromosome	IEA
GO:0005694	Component	Chromosome	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005829	Component	Cytosol	TAS
GO:0006302	Process	Double-strand break repair	IBA
GO:0006302	Process	Double-strand break repair	IMP	17349791
GO:0007064	Process	Mitotic sister chromatid cohesion	IBA
GO:0007064	Process	Mitotic sister chromatid cohesion	IEA
GO:0007064	Process	Mitotic sister chromatid cohesion	IMP	15837422, 17349791, 21111234
GO:0007064	Process	Mitotic sister chromatid cohesion	IPI	21111234
GO:0044877	Function	Protein-containing complex binding	IDA	15837422
GO:0051301	Process	Cell division	IEA

MIM	HGNC	e!Ensembl
609374	14626	ENSG00000146670

Protein

UniProt ID

Q96FF9

Protein name

Sororin (Cell division cycle-associated protein 5) (p35)

Protein function

Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is ac

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF09666	Sororin	89 → 215	Sororin protein	Family

Sequence

MSGRRTRSGGAAQRSGPRAPSPTKPLRRSQRKSGSELPSILPEIWPKTPSAAAVRKPIVL
KRIVAHAVEVPAVQSPRRSPRISFFLEKENEPPGRELTKEDLFKTHSVPATPTSTPVPNP
EAESSSKEGELDARDLEMSKKVRRSYSRLETLGSASTSTPGRRSCFGFEGLLGAEDLSGV
SPVVCSKLTEVPRVCAKPWAPDMTLPGISPPPEKQKRKKKKMPEILKTELDEWAAAMNAE
FEAAEQFDLLVE

Sequence length

252

Interactions

View interactions

	KEGG		Reactome
	Cell cycle MicroRNAs in cancer		Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Resolution of Sister Chromatid Cohesion

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Metabolic Syndrome	Metabolic syndrome	N/A	N/A	GWAS

Show/Hide Text Mining Associations (24)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	32149105, 35354488, 35373420
Atrial Fibrillation	Associate	35003319
Breast Neoplasms	Stimulate	31280346
Breast Neoplasms	Associate	31758680, 35506437, 36004470
Carcinogenesis	Associate	36233194
Carcinoma Hepatocellular	Associate	31811111, 32694239, 33830865, 34737790, 39874008
Carcinoma Non Small Cell Lung	Associate	35373420
Carcinoma Ovarian Epithelial	Associate	34143800
Colorectal Neoplasms	Associate	33190424
Fibrosarcoma	Associate	35993042
Fibrosis	Associate	31811111
Glioblastoma	Stimulate	33449451
Lung Neoplasms	Associate	35373420
Lymphatic Metastasis	Stimulate	34509929
Lymphoma Non Hodgkin	Associate	37828118
Mesothelioma Malignant	Associate	27840913
Neoplasms	Associate	21878504, 32694239, 32716971, 33190424, 33437202, 34082692, 34143800, 34509929, 35373420, 35506437, 36004470
Ovarian Neoplasms	Associate	34077004
Pancreatic Neoplasms	Associate	33437202
Prostatic Neoplasms	Associate	34509929, 35119046
Squamous Cell Carcinoma of Head and Neck	Associate	32716971
Stomach Neoplasms	Associate	32759885
Tertiary Lymphoid Structures	Associate	31280346
Urinary Bladder Neoplasms	Associate	35993042

CDCA5 (cell division cycle associated 5)