Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	112885
Gene name	PHD finger protein 21B
Gene symbol	PHF21B
Synonyms (NCBI Gene)	BHC80LPHF4
Chromosome	22
Chromosome location	22q13.31

161

Show/Hide all (161)

miRTarBase ID	miRNA	Experiments	Reference
MIRT022492	hsa-miR-124-3p	Microarray	18668037
MIRT640005	hsa-miR-4267	HITS-CLIP	23824327
MIRT640004	hsa-miR-1470	HITS-CLIP	23824327
MIRT640003	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT640002	hsa-miR-5193	HITS-CLIP	23824327
MIRT640001	hsa-miR-3183	HITS-CLIP	23824327
MIRT640000	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT639999	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT639998	hsa-miR-4469	HITS-CLIP	23824327
MIRT639997	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT639996	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT655156	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT655155	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT655154	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT639995	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT639994	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT639992	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT639991	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT639990	hsa-miR-4279	HITS-CLIP	23824327
MIRT655153	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT639989	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT640005	hsa-miR-4267	HITS-CLIP	23824327
MIRT640004	hsa-miR-1470	HITS-CLIP	23824327
MIRT640003	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT640002	hsa-miR-5193	HITS-CLIP	23824327
MIRT640001	hsa-miR-3183	HITS-CLIP	23824327
MIRT640000	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT639999	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT639998	hsa-miR-4469	HITS-CLIP	23824327
MIRT639997	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT639996	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT639995	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT639994	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT639993	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT639992	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT639991	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT639990	hsa-miR-4279	HITS-CLIP	23824327
MIRT639989	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT640005	hsa-miR-4267	HITS-CLIP	23824327
MIRT640004	hsa-miR-1470	HITS-CLIP	23824327
MIRT640003	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT640002	hsa-miR-5193	HITS-CLIP	23824327
MIRT640001	hsa-miR-3183	HITS-CLIP	23824327
MIRT640000	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT639999	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT639998	hsa-miR-4469	HITS-CLIP	23824327
MIRT639997	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT639996	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT639995	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT639994	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT639993	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT639992	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT639991	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT639990	hsa-miR-4279	HITS-CLIP	23824327
MIRT639989	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT570562	hsa-miR-4747-3p	PAR-CLIP	20371350
MIRT570561	hsa-miR-4716-3p	PAR-CLIP	20371350
MIRT570560	hsa-miR-6794-5p	PAR-CLIP	20371350
MIRT570559	hsa-miR-6798-5p	PAR-CLIP	20371350
MIRT570558	hsa-miR-1915-3p	PAR-CLIP	20371350
MIRT570557	hsa-miR-6764-5p	PAR-CLIP	20371350
MIRT570556	hsa-miR-7108-3p	PAR-CLIP	20371350
MIRT570555	hsa-miR-4707-3p	PAR-CLIP	20371350
MIRT640005	hsa-miR-4267	HITS-CLIP	23824327
MIRT640004	hsa-miR-1470	HITS-CLIP	23824327
MIRT640003	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT640002	hsa-miR-5193	HITS-CLIP	23824327
MIRT640001	hsa-miR-3183	HITS-CLIP	23824327
MIRT640000	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT639999	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT639998	hsa-miR-4469	HITS-CLIP	23824327
MIRT639997	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT639996	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT655156	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT655155	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT655154	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT639995	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT639994	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT639992	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT639991	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT639990	hsa-miR-4279	HITS-CLIP	23824327
MIRT655153	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT639989	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT640005	hsa-miR-4267	HITS-CLIP	23824327
MIRT640004	hsa-miR-1470	HITS-CLIP	23824327
MIRT640003	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT640002	hsa-miR-5193	HITS-CLIP	23824327
MIRT640001	hsa-miR-3183	HITS-CLIP	23824327
MIRT640000	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT639999	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT639998	hsa-miR-4469	HITS-CLIP	23824327
MIRT639997	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT639996	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT639995	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT639994	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT639993	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT639992	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT639991	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT639990	hsa-miR-4279	HITS-CLIP	23824327
MIRT639989	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT640005	hsa-miR-4267	HITS-CLIP	23824327
MIRT640004	hsa-miR-1470	HITS-CLIP	23824327
MIRT640003	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT640002	hsa-miR-5193	HITS-CLIP	23824327
MIRT640001	hsa-miR-3183	HITS-CLIP	23824327
MIRT640000	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT639999	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT639998	hsa-miR-4469	HITS-CLIP	23824327
MIRT639997	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT639996	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT639995	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT639994	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT639993	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT639992	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT639991	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT639990	hsa-miR-4279	HITS-CLIP	23824327
MIRT639989	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT570562	hsa-miR-4747-3p	PAR-CLIP	20371350
MIRT570561	hsa-miR-4716-3p	PAR-CLIP	20371350
MIRT570560	hsa-miR-6794-5p	PAR-CLIP	20371350
MIRT570559	hsa-miR-6798-5p	PAR-CLIP	20371350
MIRT570558	hsa-miR-1915-3p	PAR-CLIP	20371350
MIRT570557	hsa-miR-6764-5p	PAR-CLIP	20371350
MIRT570556	hsa-miR-7108-3p	PAR-CLIP	20371350
MIRT570555	hsa-miR-4707-3p	PAR-CLIP	20371350
MIRT1230880	hsa-miR-1224-3p	CLIP-seq
MIRT1230881	hsa-miR-1245b-5p	CLIP-seq
MIRT1230882	hsa-miR-149	CLIP-seq
MIRT1230883	hsa-miR-3142	CLIP-seq
MIRT1230884	hsa-miR-645	CLIP-seq
MIRT1230885	hsa-miR-760	CLIP-seq
MIRT1230886	hsa-miR-182	CLIP-seq
MIRT1230887	hsa-miR-1913	CLIP-seq
MIRT1230888	hsa-miR-3157-5p	CLIP-seq
MIRT1230889	hsa-miR-3173-3p	CLIP-seq
MIRT1230890	hsa-miR-324-3p	CLIP-seq
MIRT1230891	hsa-miR-4470	CLIP-seq
MIRT1230892	hsa-miR-4476	CLIP-seq
MIRT1230893	hsa-miR-4533	CLIP-seq
MIRT1230894	hsa-miR-4691-3p	CLIP-seq
MIRT1230895	hsa-miR-4734	CLIP-seq
MIRT1230896	hsa-miR-4749-3p	CLIP-seq
MIRT1230897	hsa-miR-4763-5p	CLIP-seq
MIRT1230898	hsa-miR-596	CLIP-seq
MIRT1230899	hsa-miR-885-3p	CLIP-seq
MIRT2067790	hsa-miR-548ac	CLIP-seq
MIRT2067791	hsa-miR-548d-3p	CLIP-seq
MIRT2067792	hsa-miR-548z	CLIP-seq
MIRT2067793	hsa-miR-595	CLIP-seq
MIRT2295243	hsa-miR-1231	CLIP-seq
MIRT1230891	hsa-miR-4470	CLIP-seq
MIRT2295244	hsa-miR-4514	CLIP-seq
MIRT2295245	hsa-miR-4645-5p	CLIP-seq
MIRT2295246	hsa-miR-4673	CLIP-seq
MIRT2295247	hsa-miR-4692	CLIP-seq
MIRT2687839	hsa-miR-3155	CLIP-seq
MIRT2687840	hsa-miR-3155b	CLIP-seq
MIRT2687841	hsa-miR-3202	CLIP-seq
MIRT2687842	hsa-miR-4438	CLIP-seq
MIRT1230892	hsa-miR-4476	CLIP-seq
MIRT2687843	hsa-miR-484	CLIP-seq

Show/Hide all (3)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	26871637
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
616727	25161	ENSG00000056487

Q96EK2

Protein name

PHD finger protein 21B

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00628	PHD	354 → 399	PHD-finger	Domain

Sequence

MELQSRPEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGTITAVPVTGPQVSSLQR
LAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKNPSPALPTANNTV
SHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAVSVVSDSIKVQP
LLISADNKPPPRLLSSPHPATHHCPLHPSSLPLTPPSPSLSPSPLHGIFQVIIIQPQVQT
QPESTAESRPPTEEPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKR
QERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKR
GANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGVPWTGMLAIVHSYV
THKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCLELKTSLLARQRGTQSSLD
RLRALLRLIQGEQLLQVTMTTTSPAPLLAGPWTKPSVAATHPTVQHPQGHN

Sequence length

531

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ERECTILE DYSFUNCTION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
POST-TRAUMATIC STRESS DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SPONDYLOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Colorectal Neoplasms	Associate	25454821	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Inhibit	25454821	★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Associate	25454821	★★★★★ ★☆☆☆☆ Found in Text Mining only

PHF21B (PHD finger protein 21B)