Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	112858
Gene name Gene Name - the full gene name approved by the HGNC.	TP53 regulating kinase
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TP53RK
Synonyms (NCBI Gene) Gene synonyms aliases	BUD32, C20orf64, GAMOS4, Nori-2, Nori-2p, PRPK, TPRKB, dJ101A2
Disease Acronyms (UniProt) Disease acronyms from UniProt database	GAMOS4
Chromosome Chromosome number	20
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	20q13.12

Show/Hide all(6)

SNP ID	Visualize variation	Clinical significance	Consequence
rs553547069	G>A	Likely-pathogenic	Coding sequence variant, missense variant
rs773814837	C>A,T	Pathogenic	Missense variant, coding sequence variant
rs776588426	C>A,T	Pathogenic	Missense variant, coding sequence variant
rs886913294	G>A	Likely-pathogenic	Missense variant, coding sequence variant
rs1431526147	T>-	Pathogenic	Coding sequence variant, frameshift variant
rs1432218739	G>A,C,T	Pathogenic	Coding sequence variant, missense variant

Show/Hide all(395)

miRTarBase ID	miRNA	Experiments	Reference
MIRT048227	hsa-miR-196a-5p	CLASH	23622248
MIRT037962	hsa-miR-505-5p	CLASH	23622248
MIRT550710	hsa-miR-4311	PAR-CLIP	20371350
MIRT296120	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT550709	hsa-miR-345-3p	PAR-CLIP	20371350
MIRT550708	hsa-miR-4766-5p	PAR-CLIP	20371350
MIRT550707	hsa-miR-3913-3p	PAR-CLIP	20371350
MIRT550706	hsa-miR-4725-5p	PAR-CLIP	20371350
MIRT550705	hsa-miR-539-5p	PAR-CLIP	20371350
MIRT550704	hsa-miR-489-3p	PAR-CLIP	20371350
MIRT550703	hsa-miR-514a-3p	PAR-CLIP	20371350
MIRT550702	hsa-miR-514b-3p	PAR-CLIP	20371350
MIRT550710	hsa-miR-4311	PAR-CLIP	21572407
MIRT296120	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT550709	hsa-miR-345-3p	PAR-CLIP	21572407
MIRT550708	hsa-miR-4766-5p	PAR-CLIP	21572407
MIRT550707	hsa-miR-3913-3p	PAR-CLIP	21572407
MIRT550706	hsa-miR-4725-5p	PAR-CLIP	21572407
MIRT550705	hsa-miR-539-5p	PAR-CLIP	21572407
MIRT550704	hsa-miR-489-3p	PAR-CLIP	21572407
MIRT550703	hsa-miR-514a-3p	PAR-CLIP	21572407
MIRT550702	hsa-miR-514b-3p	PAR-CLIP	21572407
MIRT550710	hsa-miR-4311	PAR-CLIP	20371350
MIRT296120	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT550709	hsa-miR-345-3p	PAR-CLIP	20371350
MIRT550708	hsa-miR-4766-5p	PAR-CLIP	20371350
MIRT550707	hsa-miR-3913-3p	PAR-CLIP	20371350
MIRT550706	hsa-miR-4725-5p	PAR-CLIP	20371350
MIRT550705	hsa-miR-539-5p	PAR-CLIP	20371350
MIRT550704	hsa-miR-489-3p	PAR-CLIP	20371350
MIRT550703	hsa-miR-514a-3p	PAR-CLIP	20371350
MIRT550702	hsa-miR-514b-3p	PAR-CLIP	20371350
MIRT550710	hsa-miR-4311	PAR-CLIP	21572407
MIRT296120	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT550709	hsa-miR-345-3p	PAR-CLIP	21572407
MIRT550708	hsa-miR-4766-5p	PAR-CLIP	21572407
MIRT550707	hsa-miR-3913-3p	PAR-CLIP	21572407
MIRT550706	hsa-miR-4725-5p	PAR-CLIP	21572407
MIRT550705	hsa-miR-539-5p	PAR-CLIP	21572407
MIRT550704	hsa-miR-489-3p	PAR-CLIP	21572407
MIRT550703	hsa-miR-514a-3p	PAR-CLIP	21572407
MIRT550702	hsa-miR-514b-3p	PAR-CLIP	21572407
MIRT1448616	hsa-let-7a	CLIP-seq
MIRT1448617	hsa-let-7b	CLIP-seq
MIRT1448618	hsa-let-7c	CLIP-seq
MIRT1448619	hsa-let-7d	CLIP-seq
MIRT1448620	hsa-let-7e	CLIP-seq
MIRT1448621	hsa-let-7f	CLIP-seq
MIRT1448622	hsa-let-7g	CLIP-seq
MIRT1448623	hsa-let-7i	CLIP-seq
MIRT1448624	hsa-miR-103b	CLIP-seq
MIRT1448625	hsa-miR-1183	CLIP-seq
MIRT1448626	hsa-miR-1193	CLIP-seq
MIRT1448627	hsa-miR-1224-3p	CLIP-seq
MIRT1448628	hsa-miR-1260	CLIP-seq
MIRT1448629	hsa-miR-1260b	CLIP-seq
MIRT1448630	hsa-miR-1273f	CLIP-seq
MIRT1448631	hsa-miR-1278	CLIP-seq
MIRT1448632	hsa-miR-128	CLIP-seq
MIRT1448633	hsa-miR-1280	CLIP-seq
MIRT1448634	hsa-miR-1294	CLIP-seq
MIRT1448635	hsa-miR-129-5p	CLIP-seq
MIRT1448636	hsa-miR-1323	CLIP-seq
MIRT1448637	hsa-miR-1343	CLIP-seq
MIRT1448638	hsa-miR-143	CLIP-seq
MIRT1448639	hsa-miR-146a	CLIP-seq
MIRT1448640	hsa-miR-146b-5p	CLIP-seq
MIRT1448641	hsa-miR-147	CLIP-seq
MIRT1448642	hsa-miR-1470	CLIP-seq
MIRT1448643	hsa-miR-1827	CLIP-seq
MIRT1448644	hsa-miR-188-3p	CLIP-seq
MIRT1448645	hsa-miR-1914	CLIP-seq
MIRT1448646	hsa-miR-197	CLIP-seq
MIRT1448647	hsa-miR-2053	CLIP-seq
MIRT1448648	hsa-miR-22	CLIP-seq
MIRT1448649	hsa-miR-224	CLIP-seq
MIRT1448650	hsa-miR-2467-3p	CLIP-seq
MIRT1448651	hsa-miR-27a	CLIP-seq
MIRT1448652	hsa-miR-27b	CLIP-seq
MIRT1448653	hsa-miR-3065-3p	CLIP-seq
MIRT1448654	hsa-miR-3065-5p	CLIP-seq
MIRT1448655	hsa-miR-3156-3p	CLIP-seq
MIRT1448656	hsa-miR-3159	CLIP-seq
MIRT1448657	hsa-miR-3163	CLIP-seq
MIRT1448658	hsa-miR-3187-3p	CLIP-seq
MIRT1448659	hsa-miR-3189-3p	CLIP-seq
MIRT1448660	hsa-miR-3190	CLIP-seq
MIRT1448661	hsa-miR-324-5p	CLIP-seq
MIRT1448662	hsa-miR-330-3p	CLIP-seq
MIRT1448663	hsa-miR-340	CLIP-seq
MIRT1448664	hsa-miR-3607-3p	CLIP-seq
MIRT1448665	hsa-miR-3614-3p	CLIP-seq
MIRT1448666	hsa-miR-362-5p	CLIP-seq
MIRT1448667	hsa-miR-365	CLIP-seq
MIRT1448668	hsa-miR-3652	CLIP-seq
MIRT1448669	hsa-miR-3653	CLIP-seq
MIRT1448670	hsa-miR-3658	CLIP-seq
MIRT1448671	hsa-miR-3678-3p	CLIP-seq
MIRT1448672	hsa-miR-3680	CLIP-seq
MIRT1448673	hsa-miR-376a	CLIP-seq
MIRT1448674	hsa-miR-376b	CLIP-seq
MIRT1448675	hsa-miR-3911	CLIP-seq
MIRT1448676	hsa-miR-3915	CLIP-seq
MIRT1448677	hsa-miR-3928	CLIP-seq
MIRT1448678	hsa-miR-3936	CLIP-seq
MIRT1448679	hsa-miR-3944-5p	CLIP-seq
MIRT1448680	hsa-miR-412	CLIP-seq
MIRT1448681	hsa-miR-4260	CLIP-seq
MIRT1448682	hsa-miR-4263	CLIP-seq
MIRT1448683	hsa-miR-4291	CLIP-seq
MIRT1448684	hsa-miR-4301	CLIP-seq
MIRT1448685	hsa-miR-4302	CLIP-seq
MIRT1448686	hsa-miR-4310	CLIP-seq
MIRT1448687	hsa-miR-4316	CLIP-seq
MIRT1448688	hsa-miR-432	CLIP-seq
MIRT1448689	hsa-miR-4328	CLIP-seq
MIRT1448690	hsa-miR-4430	CLIP-seq
MIRT1448691	hsa-miR-4450	CLIP-seq
MIRT1448692	hsa-miR-4455	CLIP-seq
MIRT1448693	hsa-miR-4457	CLIP-seq
MIRT1448694	hsa-miR-4458	CLIP-seq
MIRT1448695	hsa-miR-4477a	CLIP-seq
MIRT1448696	hsa-miR-4496	CLIP-seq
MIRT1448697	hsa-miR-4500	CLIP-seq
MIRT1448698	hsa-miR-4501	CLIP-seq
MIRT1448699	hsa-miR-4505	CLIP-seq
MIRT1448700	hsa-miR-450b-5p	CLIP-seq
MIRT1448701	hsa-miR-4520a-3p	CLIP-seq
MIRT1448702	hsa-miR-4520b-3p	CLIP-seq
MIRT1448703	hsa-miR-4529-5p	CLIP-seq
MIRT1448704	hsa-miR-4632	CLIP-seq
MIRT1448705	hsa-miR-4640-5p	CLIP-seq
MIRT1448706	hsa-miR-4645-3p	CLIP-seq
MIRT1448707	hsa-miR-4661-5p	CLIP-seq
MIRT1448708	hsa-miR-4667-3p	CLIP-seq
MIRT1448709	hsa-miR-4667-5p	CLIP-seq
MIRT1448710	hsa-miR-4681	CLIP-seq
MIRT1448711	hsa-miR-4693-3p	CLIP-seq
MIRT1448712	hsa-miR-4694-5p	CLIP-seq
MIRT1448713	hsa-miR-4700-5p	CLIP-seq
MIRT1448714	hsa-miR-4708-5p	CLIP-seq
MIRT1448715	hsa-miR-4709-5p	CLIP-seq
MIRT1448716	hsa-miR-4726-5p	CLIP-seq
MIRT1448717	hsa-miR-4731-5p	CLIP-seq
MIRT1448718	hsa-miR-4738-3p	CLIP-seq
MIRT1448719	hsa-miR-4760-3p	CLIP-seq
MIRT1448720	hsa-miR-4770	CLIP-seq
MIRT1448721	hsa-miR-4773	CLIP-seq
MIRT1448722	hsa-miR-4777-3p	CLIP-seq
MIRT1448723	hsa-miR-4789-5p	CLIP-seq
MIRT1448724	hsa-miR-4795-3p	CLIP-seq
MIRT1448725	hsa-miR-4796-5p	CLIP-seq
MIRT1448726	hsa-miR-4799-5p	CLIP-seq
MIRT1448727	hsa-miR-489	CLIP-seq
MIRT1448728	hsa-miR-499a-5p	CLIP-seq
MIRT1448729	hsa-miR-500b	CLIP-seq
MIRT1448730	hsa-miR-501-5p	CLIP-seq
MIRT1448731	hsa-miR-507	CLIP-seq
MIRT1448732	hsa-miR-512-5p	CLIP-seq
MIRT1448733	hsa-miR-513b	CLIP-seq
MIRT1448734	hsa-miR-514	CLIP-seq
MIRT1448735	hsa-miR-515-5p	CLIP-seq
MIRT1448736	hsa-miR-532-3p	CLIP-seq
MIRT1448737	hsa-miR-548a-3p	CLIP-seq
MIRT1448738	hsa-miR-548aa	CLIP-seq
MIRT1448739	hsa-miR-548e	CLIP-seq
MIRT1448740	hsa-miR-548f	CLIP-seq
MIRT1448741	hsa-miR-548k	CLIP-seq
MIRT1448742	hsa-miR-548o	CLIP-seq
MIRT1448743	hsa-miR-549	CLIP-seq
MIRT1448744	hsa-miR-550a	CLIP-seq
MIRT1448745	hsa-miR-557	CLIP-seq
MIRT1448746	hsa-miR-569	CLIP-seq
MIRT1448747	hsa-miR-570	CLIP-seq
MIRT1448748	hsa-miR-574-5p	CLIP-seq
MIRT1448749	hsa-miR-576-5p	CLIP-seq
MIRT1448750	hsa-miR-589	CLIP-seq
MIRT1448751	hsa-miR-601	CLIP-seq
MIRT1448752	hsa-miR-609	CLIP-seq
MIRT1448753	hsa-miR-622	CLIP-seq
MIRT1448754	hsa-miR-644	CLIP-seq
MIRT1448755	hsa-miR-648	CLIP-seq
MIRT1448756	hsa-miR-98	CLIP-seq
MIRT1448627	hsa-miR-1224-3p	CLIP-seq
MIRT2134285	hsa-miR-1254	CLIP-seq
MIRT1448628	hsa-miR-1260	CLIP-seq
MIRT1448629	hsa-miR-1260b	CLIP-seq
MIRT1448632	hsa-miR-128	CLIP-seq
MIRT1448633	hsa-miR-1280	CLIP-seq
MIRT1448634	hsa-miR-1294	CLIP-seq
MIRT2134286	hsa-miR-138	CLIP-seq
MIRT1448639	hsa-miR-146a	CLIP-seq
MIRT1448640	hsa-miR-146b-5p	CLIP-seq
MIRT1448651	hsa-miR-27a	CLIP-seq
MIRT1448652	hsa-miR-27b	CLIP-seq
MIRT1448654	hsa-miR-3065-5p	CLIP-seq
MIRT2134287	hsa-miR-3116	CLIP-seq
MIRT2134288	hsa-miR-3133	CLIP-seq
MIRT2134289	hsa-miR-3192	CLIP-seq
MIRT2134290	hsa-miR-3202	CLIP-seq
MIRT2134291	hsa-miR-323b-5p	CLIP-seq
MIRT1448662	hsa-miR-330-3p	CLIP-seq
MIRT2134292	hsa-miR-34b	CLIP-seq
MIRT1448665	hsa-miR-3614-3p	CLIP-seq
MIRT2134293	hsa-miR-3614-5p	CLIP-seq
MIRT2134294	hsa-miR-3622b-5p	CLIP-seq
MIRT1448668	hsa-miR-3652	CLIP-seq
MIRT2134295	hsa-miR-3662	CLIP-seq
MIRT1448672	hsa-miR-3680	CLIP-seq
MIRT2134296	hsa-miR-3713	CLIP-seq
MIRT2134297	hsa-miR-3908	CLIP-seq
MIRT2134298	hsa-miR-3909	CLIP-seq
MIRT2134299	hsa-miR-3942-5p	CLIP-seq
MIRT2134300	hsa-miR-3978	CLIP-seq
MIRT1448681	hsa-miR-4260	CLIP-seq
MIRT1448683	hsa-miR-4291	CLIP-seq
MIRT2134301	hsa-miR-4307	CLIP-seq
MIRT1448686	hsa-miR-4310	CLIP-seq
MIRT2134302	hsa-miR-4314	CLIP-seq
MIRT1448687	hsa-miR-4316	CLIP-seq
MIRT1448690	hsa-miR-4430	CLIP-seq
MIRT2134303	hsa-miR-4434	CLIP-seq
MIRT1448691	hsa-miR-4450	CLIP-seq
MIRT2134304	hsa-miR-4476	CLIP-seq
MIRT1448698	hsa-miR-4501	CLIP-seq
MIRT1448699	hsa-miR-4505	CLIP-seq
MIRT2134305	hsa-miR-4516	CLIP-seq
MIRT1448705	hsa-miR-4640-5p	CLIP-seq
MIRT1448706	hsa-miR-4645-3p	CLIP-seq
MIRT2134306	hsa-miR-4646-5p	CLIP-seq
MIRT2134307	hsa-miR-4653-3p	CLIP-seq
MIRT1448707	hsa-miR-4661-5p	CLIP-seq
MIRT1448709	hsa-miR-4667-5p	CLIP-seq
MIRT2134308	hsa-miR-4690-3p	CLIP-seq
MIRT2134309	hsa-miR-4697-3p	CLIP-seq
MIRT2134310	hsa-miR-4698	CLIP-seq
MIRT2134311	hsa-miR-4699-3p	CLIP-seq
MIRT1448713	hsa-miR-4700-5p	CLIP-seq
MIRT2134312	hsa-miR-4703-5p	CLIP-seq
MIRT2134313	hsa-miR-4705	CLIP-seq
MIRT2134314	hsa-miR-4718	CLIP-seq
MIRT2134315	hsa-miR-4720-5p	CLIP-seq
MIRT1448716	hsa-miR-4726-5p	CLIP-seq
MIRT1448717	hsa-miR-4731-5p	CLIP-seq
MIRT2134316	hsa-miR-4733-5p	CLIP-seq
MIRT2134317	hsa-miR-4742-3p	CLIP-seq
MIRT2134318	hsa-miR-4760-5p	CLIP-seq
MIRT2134319	hsa-miR-4766-3p	CLIP-seq
MIRT1448722	hsa-miR-4777-3p	CLIP-seq
MIRT2134320	hsa-miR-4799-3p	CLIP-seq
MIRT2134321	hsa-miR-5096	CLIP-seq
MIRT2134322	hsa-miR-511	CLIP-seq
MIRT1448735	hsa-miR-515-5p	CLIP-seq
MIRT2134323	hsa-miR-548g	CLIP-seq
MIRT2134324	hsa-miR-579	CLIP-seq
MIRT2134325	hsa-miR-587	CLIP-seq
MIRT1448750	hsa-miR-589	CLIP-seq
MIRT2134326	hsa-miR-607	CLIP-seq
MIRT2134327	hsa-miR-661	CLIP-seq
MIRT2134328	hsa-miR-943	CLIP-seq
MIRT2355498	hsa-miR-124	CLIP-seq
MIRT2355499	hsa-miR-1245b-3p	CLIP-seq
MIRT1448632	hsa-miR-128	CLIP-seq
MIRT1448634	hsa-miR-1294	CLIP-seq
MIRT1448647	hsa-miR-2053	CLIP-seq
MIRT1448649	hsa-miR-224	CLIP-seq
MIRT1448651	hsa-miR-27a	CLIP-seq
MIRT1448652	hsa-miR-27b	CLIP-seq
MIRT1448654	hsa-miR-3065-5p	CLIP-seq
MIRT1448655	hsa-miR-3156-3p	CLIP-seq
MIRT1448657	hsa-miR-3163	CLIP-seq
MIRT2355500	hsa-miR-3200-5p	CLIP-seq
MIRT2355501	hsa-miR-323b-3p	CLIP-seq
MIRT2355502	hsa-miR-3616-5p	CLIP-seq
MIRT1448666	hsa-miR-362-5p	CLIP-seq
MIRT2355503	hsa-miR-3647-5p	CLIP-seq
MIRT1448668	hsa-miR-3652	CLIP-seq
MIRT2355504	hsa-miR-3682-3p	CLIP-seq
MIRT2355505	hsa-miR-371b-5p	CLIP-seq
MIRT1448680	hsa-miR-412	CLIP-seq
MIRT2355506	hsa-miR-4251	CLIP-seq
MIRT1448683	hsa-miR-4291	CLIP-seq
MIRT1448684	hsa-miR-4301	CLIP-seq
MIRT1448686	hsa-miR-4310	CLIP-seq
MIRT1448687	hsa-miR-4316	CLIP-seq
MIRT2355507	hsa-miR-4329	CLIP-seq
MIRT1448690	hsa-miR-4430	CLIP-seq
MIRT1448691	hsa-miR-4450	CLIP-seq
MIRT1448692	hsa-miR-4455	CLIP-seq
MIRT1448693	hsa-miR-4457	CLIP-seq
MIRT1448698	hsa-miR-4501	CLIP-seq
MIRT1448699	hsa-miR-4505	CLIP-seq
MIRT1448706	hsa-miR-4645-3p	CLIP-seq
MIRT2355508	hsa-miR-4658	CLIP-seq
MIRT1448709	hsa-miR-4667-5p	CLIP-seq
MIRT1448712	hsa-miR-4694-5p	CLIP-seq
MIRT2134310	hsa-miR-4698	CLIP-seq
MIRT1448713	hsa-miR-4700-5p	CLIP-seq
MIRT1448717	hsa-miR-4731-5p	CLIP-seq
MIRT2355509	hsa-miR-4758-5p	CLIP-seq
MIRT2355510	hsa-miR-4765	CLIP-seq
MIRT1448721	hsa-miR-4773	CLIP-seq
MIRT2355511	hsa-miR-4789-3p	CLIP-seq
MIRT2355512	hsa-miR-4795-5p	CLIP-seq
MIRT1448729	hsa-miR-500b	CLIP-seq
MIRT2355513	hsa-miR-506	CLIP-seq
MIRT1448733	hsa-miR-513b	CLIP-seq
MIRT2355514	hsa-miR-519a	CLIP-seq
MIRT2355515	hsa-miR-519b-3p	CLIP-seq
MIRT2355516	hsa-miR-519c-3p	CLIP-seq
MIRT2355517	hsa-miR-526b	CLIP-seq
MIRT2355518	hsa-miR-545	CLIP-seq
MIRT2355519	hsa-miR-548an	CLIP-seq
MIRT1448743	hsa-miR-549	CLIP-seq
MIRT1448746	hsa-miR-569	CLIP-seq
MIRT2355520	hsa-miR-573	CLIP-seq
MIRT1448752	hsa-miR-609	CLIP-seq
MIRT2355521	hsa-miR-642b	CLIP-seq
MIRT2355522	hsa-miR-888	CLIP-seq
MIRT1448626	hsa-miR-1193	CLIP-seq
MIRT2396234	hsa-miR-3144-5p	CLIP-seq
MIRT2396235	hsa-miR-3191	CLIP-seq
MIRT2396236	hsa-miR-4652-5p	CLIP-seq
MIRT1448632	hsa-miR-128	CLIP-seq
MIRT2462185	hsa-miR-136	CLIP-seq
MIRT1448651	hsa-miR-27a	CLIP-seq
MIRT1448652	hsa-miR-27b	CLIP-seq
MIRT1448657	hsa-miR-3163	CLIP-seq
MIRT1448668	hsa-miR-3652	CLIP-seq
MIRT2134295	hsa-miR-3662	CLIP-seq
MIRT1448683	hsa-miR-4291	CLIP-seq
MIRT1448686	hsa-miR-4310	CLIP-seq
MIRT1448690	hsa-miR-4430	CLIP-seq
MIRT1448691	hsa-miR-4450	CLIP-seq
MIRT1448699	hsa-miR-4505	CLIP-seq
MIRT1448709	hsa-miR-4667-5p	CLIP-seq
MIRT1448713	hsa-miR-4700-5p	CLIP-seq
MIRT1448717	hsa-miR-4731-5p	CLIP-seq
MIRT1448735	hsa-miR-515-5p	CLIP-seq
MIRT1448632	hsa-miR-128	CLIP-seq
MIRT1448651	hsa-miR-27a	CLIP-seq
MIRT1448652	hsa-miR-27b	CLIP-seq
MIRT1448668	hsa-miR-3652	CLIP-seq
MIRT1448683	hsa-miR-4291	CLIP-seq
MIRT1448686	hsa-miR-4310	CLIP-seq
MIRT1448690	hsa-miR-4430	CLIP-seq
MIRT1448691	hsa-miR-4450	CLIP-seq
MIRT1448699	hsa-miR-4505	CLIP-seq
MIRT1448709	hsa-miR-4667-5p	CLIP-seq
MIRT1448713	hsa-miR-4700-5p	CLIP-seq
MIRT1448717	hsa-miR-4731-5p	CLIP-seq
MIRT1448632	hsa-miR-128	CLIP-seq
MIRT2649123	hsa-miR-1324	CLIP-seq
MIRT1448651	hsa-miR-27a	CLIP-seq
MIRT1448652	hsa-miR-27b	CLIP-seq
MIRT2649124	hsa-miR-3123	CLIP-seq
MIRT2649125	hsa-miR-342-3p	CLIP-seq
MIRT1448666	hsa-miR-362-5p	CLIP-seq
MIRT1448668	hsa-miR-3652	CLIP-seq
MIRT2649126	hsa-miR-3672	CLIP-seq
MIRT1448683	hsa-miR-4291	CLIP-seq
MIRT1448686	hsa-miR-4310	CLIP-seq
MIRT1448690	hsa-miR-4430	CLIP-seq
MIRT1448691	hsa-miR-4450	CLIP-seq
MIRT1448693	hsa-miR-4457	CLIP-seq
MIRT1448699	hsa-miR-4505	CLIP-seq
MIRT1448709	hsa-miR-4667-5p	CLIP-seq
MIRT1448713	hsa-miR-4700-5p	CLIP-seq
MIRT1448717	hsa-miR-4731-5p	CLIP-seq
MIRT2649127	hsa-miR-4759	CLIP-seq
MIRT2649128	hsa-miR-4793-5p	CLIP-seq
MIRT2649129	hsa-miR-494	CLIP-seq
MIRT1448729	hsa-miR-500b	CLIP-seq
MIRT1448733	hsa-miR-513b	CLIP-seq
MIRT1448632	hsa-miR-128	CLIP-seq
MIRT1448651	hsa-miR-27a	CLIP-seq
MIRT1448652	hsa-miR-27b	CLIP-seq
MIRT2649124	hsa-miR-3123	CLIP-seq
MIRT2649125	hsa-miR-342-3p	CLIP-seq
MIRT1448666	hsa-miR-362-5p	CLIP-seq
MIRT1448668	hsa-miR-3652	CLIP-seq
MIRT2649126	hsa-miR-3672	CLIP-seq
MIRT1448683	hsa-miR-4291	CLIP-seq
MIRT1448686	hsa-miR-4310	CLIP-seq
MIRT1448690	hsa-miR-4430	CLIP-seq
MIRT1448691	hsa-miR-4450	CLIP-seq
MIRT1448693	hsa-miR-4457	CLIP-seq
MIRT1448699	hsa-miR-4505	CLIP-seq
MIRT1448709	hsa-miR-4667-5p	CLIP-seq
MIRT1448713	hsa-miR-4700-5p	CLIP-seq
MIRT1448717	hsa-miR-4731-5p	CLIP-seq
MIRT2649127	hsa-miR-4759	CLIP-seq
MIRT2649128	hsa-miR-4793-5p	CLIP-seq
MIRT1448729	hsa-miR-500b	CLIP-seq
MIRT1448733	hsa-miR-513b	CLIP-seq

Show/Hide all(20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000408	Component	EKC/KEOPS complex	IBA	21873635
GO:0000408	Component	EKC/KEOPS complex	IDA	27903914, 28805828
GO:0002039	Function	P53 binding	IDA	11546806
GO:0004674	Function	Protein serine/threonine kinase activity	IBA	21873635
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	11546806
GO:0004674	Function	Protein serine/threonine kinase activity	TAS
GO:0005515	Function	Protein binding	IPI	11546806, 12659830, 16189514, 23414517, 23455922, 25416956, 27903914, 28514442, 28805828, 31515488, 32296183
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	11546806, 27903914, 28805828
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IDA	28805828
GO:0006468	Process	Protein phosphorylation	IBA	21873635
GO:0006468	Process	Protein phosphorylation	IDA	11546806
GO:0008033	Process	TRNA processing	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0070525	Process	TRNA threonylcarbamoyladenosine metabolic process	IBA	21873635
GO:0106310	Function	Protein serine kinase activity	IEA
GO:0106311	Function	Protein threonine kinase activity	IEA
GO:1901796	Process	Regulation of signal transduction by p53 class mediator	TAS

MIM	HGNC	e!Ensembl
608679	16197	ENSG00000172315

Protein

UniProt ID

Q96S44

Protein name

EKC/KEOPS complex subunit TP53RK (EC 3.6.-.-) (Atypical serine/threonine protein kinase TP53RK) (Nori-2) (TP53-regulating kinase) (EC 2.7.11.1) (p53-related protein kinase)

Protein function

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:27903914). The complex is probably

PDB

6WQX , 7SZA , 7SZB , 7SZC , 7SZD

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF06293	Kdo	49 → 225		Family

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in testis. Weakly expressed in heart kidney and spleen. {ECO:0000269|PubMed:11546806}.

Sequence

MAAARATTPADGEEPAPEAEALAAARERSSRFLSGLELVKQGAEARVFRGRFQGRAAVIK
HRFPKGYRHPALEARLGRRRTVQEARALLRCRRAGISAPVVFFVDYASNCLYMEEIEGSV
TVRDYIQSTMETEKTPQGLSNLAKTIGQVLARMHDEDLIHGDLTTSNMLLKPPLEQLNIV
LIDFGLSFISALPEDKGVDLYVLEKAFLSTHPNTETVFEAFLKSYSTSSKKARPVLKKLD
EVRLRGRKRSMVG

Sequence length

253

Interactions

View interactions

	Reactome
			Regulation of TP53 Activity through Phosphorylation

Show/Hide Causal Diseases (7)

Disease term	Disease name	dbSNP ID	References
Causal
Developmental delay	Global developmental delay	rs28941770, rs199469464, rs281865469, rs143747297, rs398123009, rs587777428, rs786205133, rs606231459, rs797044854, rs797045027, rs864309504, rs878853160, rs886039902, rs886042046, rs886041291 View all (32 more)
Galloway-mowat syndrome	Galloway Mowat syndrome, GALLOWAY-MOWAT SYNDROME 4, Galloway-Mowat syndrome	rs727502863, rs727502864, rs730882216, rs797044992, rs767086146, rs754099015, rs797044993, rs797044994, rs797044995, rs863223396, rs869320712, rs776760122, rs1555976610, rs1557211306, rs1557211209 View all (22 more)	28805828
Glomerulonephritis	Glomerulonephritis	rs778043831
Kidney disease	Kidney Diseases, Chronic kidney disease stage 5	rs74315342, rs749740335, rs757649673, rs112417755, rs35138315
Microcephaly	Microcephaly	rs397704721, rs267607176, rs267607177, rs397704725, rs267606717, rs267606718, rs199422202, rs121434311, rs199422203, rs199422126, rs387906274, rs121434305, rs199422125, rs199422135, rs189678019 View all (280 more)
Nephrotic syndrome	Nephrotic Syndrome	rs876657369, rs121912601, rs121912602, rs876657370, rs121912603, rs121912604, rs121912605, rs121907900, rs121907901, rs28941778, rs587776576, rs28942089, rs587776577, rs28941777, rs121907910 View all (152 more)
Polymicrogyria	Polymicrogyria	rs1558010146, rs1558003446, rs1575508937

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Galloway-Mowat Syndrome	Galloway-Mowat syndrome			GenCC

Show/Hide Text Mining Associations (7)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	40352177
Colorectal Neoplasms	Associate	26263387, 33547416
Galloway Mowat syndrome	Associate	30053862, 33547416, 36755238
Microcephaly	Associate	36755238
Multiple Myeloma	Associate	28082445
Neoplasms	Associate	33547416
Osteosarcoma	Associate	32944406

TP53RK (TP53 regulating kinase)