KLF8 (KLF transcription factor 8)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 11279 |
| Gene name | KLF transcription factor 8 |
| Gene symbol | KLF8 |
| Synonyms (NCBI Gene) |
BKLF3ZNF741
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| Chromosome | X |
| Chromosome location | Xp11.21 |
| Summary | This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in t |
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miRNA
miRNA information provided by mirtarbase database.
451
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O95600 | ||||||||||||||||||||
| Protein name | Krueppel-like factor 8 (Basic krueppel-like factor 3) (Zinc finger protein 741) | ||||||||||||||||||||
| Protein function | Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK). {ECO:0000269|Pu | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:10756197}. | ||||||||||||||||||||
| Sequence |
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| Sequence length | 359 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
13
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