PRR4 (proline rich 4)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
11272
Gene name Gene Name - the full gene name approved by the HGNC.
Proline rich 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PRR4
Synonyms (NCBI Gene) Gene synonyms aliases
LPRP, PROL4
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12p13.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the proline-rich protein family that lacks a conserved repetitive domain. This protein may play a role in protective functions in the eye. Alternative splicing result in multiple transcript variants. Read-through transcriptio
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(2)
miRTarBase ID miRNA Experiments Reference
MIRT025052 hsa-miR-181a-5p Microarray 17612493
MIRT029235 hsa-miR-26b-5p Microarray 19088304
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(4)
GO ID Ontology Definition Evidence Reference
GO:0001895 Process Retina homeostasis HEP 23580065
GO:0005515 Function Protein binding IPI 32296183
GO:0005615 Component Extracellular space HDA 22664934, 23580065
GO:0007601 Process Visual perception TAS 7544782
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
605359 18020 ENSG00000111215
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q16378
Protein name Proline-rich protein 4 (Lacrimal proline-rich protein) (Nasopharyngeal carcinoma-associated proline-rich protein 4)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15240 Pro-rich 1 → 133 Proline-rich Disordered
Tissue specificity TISSUE SPECIFICITY: Abundantly expressed in lacrimal gland where it is found in the acinar cells but not in the intralobular ducts. Also found in the submandibular gland, the parotid and sublingual glands. {ECO:0000269|PubMed:7544782}.
Sequence
Sequence length 134
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Hypertension Hypertension GWAS
Show/Hide Text Mining Associations (5)
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Non Small Cell Lung Associate 35076987
Colorectal Neoplasms Associate 36104170
Drug Hypersensitivity Associate 37876509
Dry Eye Syndromes Associate 27436115, 37876509
Neoplasms Associate 35076987