Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
11254
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier family 6 member 14
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLC6A14
Synonyms (NCBI Gene) Gene synonyms aliases
BMIQ11
Chromosome Chromosome number
X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xq23
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a be
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT030183 hsa-miR-26b-5p Microarray 19088304
MIRT1365912 hsa-miR-1228 CLIP-seq
MIRT1365913 hsa-miR-125a-5p CLIP-seq
MIRT1365914 hsa-miR-125b CLIP-seq
MIRT1365915 hsa-miR-140-5p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003333 Process Amino acid transmembrane transport TAS 10446133
GO:0005886 Component Plasma membrane TAS
GO:0005887 Component Integral component of plasma membrane IBA 21873635
GO:0006865 Process Amino acid transport TAS
GO:0009636 Process Response to toxic substance IDA 17575980
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
300444 11047 ENSG00000268104
Protein
UniProt ID Q9UN76
Protein name Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14)
Protein function Amino acid transporter that plays an important role in the absorption of amino acids in the intestinal tract. Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent man
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00209 SNF 36 588 Sodium:neurotransmitter symporter family Family
Tissue specificity TISSUE SPECIFICITY: Levels are highest in adult and fetal lung, in trachea and salivary gland. Lower levels detected in mammary gland, stomach and pituitary gland, and very low levels in colon, uterus, prostate and testis. {ECO:0000269|PubMed:10446133}.
Sequence
Sequence length 642
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Amino acid transport across the plasma membrane
Na+/Cl- dependent neurotransmitter transporters
Variant SLC6A14 may confer susceptibility towards obesity
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Cystic fibrosis CYSTIC FIBROSIS MODIFIER 1 rs113993960, rs121908745, rs77101217, rs78655421, rs77932196, rs74551128, rs76713772, rs80055610, rs121909006, rs113993959, rs121908755, rs121908758, rs75527207, rs74597325, rs75549581
View all (694 more)
22466613
Unknown
Disease term Disease name Evidence References Source
Celiac disease Celiac Disease 30097691 ClinVar
Cystic Fibrosis cystic fibrosis GenCC
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 12381519, 14563674
Carcinoma Pancreatic Ductal Associate 26106611, 31731384
Cholangiocarcinoma Associate 39670859
Colitis Ulcerative Associate 18700007, 32190668, 36272033, 36419192, 38070204
Colorectal Neoplasms Associate 15905073
Colorectal Neoplasms Stimulate 35907820
Cystic Fibrosis Associate 25771386, 30807572, 33438800
Huntington Disease Associate 22466613
Inflammation Associate 38070204
Lung Diseases Associate 30807572