ERI2 (ERI1 exoribonuclease family member 2)

Gene

• Entrez ID: 112479
• Gene name: ERI1 exoribonuclease family member 2
• Gene symbol: ERI2
• Synonyms (NCBI Gene): EXOD1, ZGRF5
• Chromosome: 16
• Chromosome location: 16p12.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT021172	hsa-miR-186-5p	Sequencing	20371350
MIRT025955	hsa-miR-7-5p	Sequencing	20371350
MIRT030187	hsa-miR-26b-5p	Microarray	19088304
MIRT194695	hsa-miR-3646	PAR-CLIP	20371350
MIRT562378	hsa-miR-5680	PAR-CLIP	20371350
MIRT562377	hsa-miR-5094	PAR-CLIP	20371350
MIRT562376	hsa-miR-5693	PAR-CLIP	20371350
MIRT562375	hsa-miR-194-3p	PAR-CLIP	20371350
MIRT562374	hsa-miR-4747-5p	PAR-CLIP	20371350
MIRT562373	hsa-miR-5196-5p	PAR-CLIP	20371350
MIRT562372	hsa-miR-203b-3p	PAR-CLIP	20371350
MIRT194695	hsa-miR-3646	PAR-CLIP	20371350
MIRT562378	hsa-miR-5680	PAR-CLIP	20371350
MIRT562377	hsa-miR-5094	PAR-CLIP	20371350
MIRT562376	hsa-miR-5693	PAR-CLIP	20371350
MIRT562375	hsa-miR-194-3p	PAR-CLIP	20371350
MIRT562374	hsa-miR-4747-5p	PAR-CLIP	20371350
MIRT562373	hsa-miR-5196-5p	PAR-CLIP	20371350
MIRT562372	hsa-miR-203b-3p	PAR-CLIP	20371350
MIRT969129	hsa-miR-1271	CLIP-seq
MIRT969130	hsa-miR-182	CLIP-seq
MIRT969131	hsa-miR-300	CLIP-seq
MIRT969132	hsa-miR-3119	CLIP-seq
MIRT969133	hsa-miR-3127-3p	CLIP-seq
MIRT969134	hsa-miR-3130-3p	CLIP-seq
MIRT969135	hsa-miR-3180-5p	CLIP-seq
MIRT969136	hsa-miR-361-5p	CLIP-seq
MIRT969137	hsa-miR-377	CLIP-seq
MIRT969138	hsa-miR-380	CLIP-seq
MIRT969139	hsa-miR-381	CLIP-seq
MIRT969140	hsa-miR-3924	CLIP-seq
MIRT969141	hsa-miR-412	CLIP-seq
MIRT969142	hsa-miR-4282	CLIP-seq
MIRT969143	hsa-miR-4426	CLIP-seq
MIRT969144	hsa-miR-4470	CLIP-seq
MIRT969145	hsa-miR-4495	CLIP-seq
MIRT969146	hsa-miR-4643	CLIP-seq
MIRT969147	hsa-miR-4645-5p	CLIP-seq
MIRT969148	hsa-miR-4647	CLIP-seq
MIRT969149	hsa-miR-4659a-3p	CLIP-seq
MIRT969150	hsa-miR-4659b-3p	CLIP-seq
MIRT969151	hsa-miR-4662b	CLIP-seq
MIRT969152	hsa-miR-4666-3p	CLIP-seq
MIRT969153	hsa-miR-4673	CLIP-seq
MIRT969154	hsa-miR-4691-5p	CLIP-seq
MIRT969155	hsa-miR-4735-5p	CLIP-seq
MIRT969156	hsa-miR-4775	CLIP-seq
MIRT969157	hsa-miR-4780	CLIP-seq
MIRT969158	hsa-miR-513a-3p	CLIP-seq
MIRT969159	hsa-miR-548c-3p	CLIP-seq
MIRT969160	hsa-miR-577	CLIP-seq
MIRT969161	hsa-miR-590-3p	CLIP-seq
MIRT969162	hsa-miR-767-5p	CLIP-seq
MIRT969163	hsa-miR-96	CLIP-seq
MIRT2525312	hsa-miR-1273d	CLIP-seq
MIRT2525313	hsa-miR-4446-5p	CLIP-seq
MIRT2525314	hsa-miR-4687-3p	CLIP-seq
MIRT969155	hsa-miR-4735-5p	CLIP-seq
MIRT2525315	hsa-miR-4755-5p	CLIP-seq
MIRT2525316	hsa-miR-548u	CLIP-seq
MIRT2525317	hsa-miR-576-5p	CLIP-seq
MIRT2525318	hsa-miR-647	CLIP-seq
MIRT2525319	hsa-miR-660	CLIP-seq
MIRT2525312	hsa-miR-1273d	CLIP-seq
MIRT2525313	hsa-miR-4446-5p	CLIP-seq
MIRT2525314	hsa-miR-4687-3p	CLIP-seq
MIRT969155	hsa-miR-4735-5p	CLIP-seq
MIRT2525315	hsa-miR-4755-5p	CLIP-seq
MIRT2525316	hsa-miR-548u	CLIP-seq
MIRT2525317	hsa-miR-576-5p	CLIP-seq
MIRT2525318	hsa-miR-647	CLIP-seq
MIRT2525319	hsa-miR-660	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000175	Function	3'-5'-RNA exonuclease activity	IBA
GO:0000175	Function	3'-5'-RNA exonuclease activity	IEA
GO:0003676	Function	Nucleic acid binding	IEA
GO:0004518	Function	Nuclease activity	IEA
GO:0004527	Function	Exonuclease activity	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: A8K979
• Protein name: ERI1 exoribonuclease 2 (EC 3.1.-.-) (Exonuclease domain-containing protein 1)
• PDB: 7N8V, 7N8W
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00929	RNase_T	38 → 226	Exonuclease	Family
  PF06839	zf-GRF	595 → 643	GRF zinc finger	Domain

• Sequence:

  MATKRLARQLGLIRRKSIAPANGNLGRSKSKQLFDYLIVIDFESTCWNDGKHHHSQEIIE
  FPAVLLNTSTGQIDSEFQAYVQPQEHPILSEFCMELTGIKQAQVDEGVPLKICLSQFCKW
  IHKIQQQKNIIFATGISEPSASEVKLCAFVTWSDWDLGVCLEYECKRKQLLKPVFLNSWI
  DLRATYKLFYRRKPKGLSGALQEVGIEFSGREHSGLDDSRNTALLAWKMIRDGCVMKITR
  SLNKVPTKKNFSILARNLNTIQVEEMSACNISIQGPSIYNKEPKNIINPHEKVQMKSICA
  NSPIKAQQDQLQVKNNIKASLHNVKSSLPLFNTKSSTSVGQLQSPTLNSPIYMQKQGKNE
  HLAFNTKSKASTVGSELVLVSTTVPTVHHVSDLEMSSTLDCLPVLADWEDVVLLPASQPE
  ENVDCTVPISDSDLEISFNSGERLMVLKELEMSSHENFGDIEETPQKSETSKSIVYKSPH
  TTIYNVKEAKDPGSDISAFKLPEHKSSTFNRVNANMSHPLVLGKHPLLSGGTKRNPCSPQ
  AFPPAKKQPFTIHEEKPTSSDCSPVRSSSWRRLPSILTSTVNLQEPWKSGKMTPPLCKCG
  RRSKRLVVSNNGPNHGKVFYCCPIGKYQENRKCCGYFKWEQTLQKERANSMVPSHSTGGL
  TFSSPETSHICDRNLSISTKNSLRLRPSMRN

• Sequence length: 691