Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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11228
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Ras association domain family member 8 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RASSF8 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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C12orf2, HOJ1 |
Chromosome
Chromosome number
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12 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12p12.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor supp |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Lung carcinoma |
Small cell carcinoma of lung |
rs1805076, rs121909071, rs121913530, rs112445441, rs121913529, rs121913535, rs121913297, rs121913279, rs104886003, rs397516975, rs11554290, rs121913364, rs121913351, rs121913369, rs121913355, rs121912470, rs121913273, rs121913281, rs121913348, rs727503093, rs121913353, rs397516890, rs397516896, rs121913378, rs397516897, rs397516977, rs397516978, rs397516979, rs397516980, rs397516981, rs397516982, rs121913240, rs17851045, rs397517086, rs121913428, rs397517094, rs397517098, rs397517106, rs121913465, rs397517108, rs397517111, rs397517112, rs397517114, rs397517116, rs1554350366, rs397517127, rs397517200, rs397517202, rs121913283, rs121913370, rs121913357, rs727503106, rs121913238, rs727503108, rs397517040, rs397516976, rs1555618025, rs1057519729, rs1584238193 View all (44 more) |
22941189 |
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Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Atrial Fibrillation |
Atrial Fibrillation |
|
|
GWAS |
Ankylosing Spondylitis |
Ankylosing Spondylitis |
|
|
GWAS |
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Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Breast Neoplasms |
Inhibit
|
29467226 |
Esophageal Squamous Cell Carcinoma |
Associate
|
36266257 |
Goiter Nodular |
Associate
|
24516056 |
Lymphatic Metastasis |
Associate
|
24516056 |
Neoplasm Metastasis |
Associate
|
24516056 |
Neoplasms |
Associate
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24516056, 34077011, 36266257 |
Neoplasms |
Inhibit
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33000257 |
Osteosarcoma |
Associate
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34077011 |
Squamous Cell Carcinoma of Head and Neck |
Inhibit
|
33000257 |
Thyroid cancer medullary |
Stimulate
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24516056 |
Thyroid Cancer Papillary |
Stimulate
|
24516056 |
Thyroid Neoplasms |
Associate
|
24516056 |
Uterine Cervical Neoplasms |
Associate
|
27626930 |
|