Gene Gene information from NCBI Gene database.
Entrez ID 11228
Gene name Ras association domain family member 8
Gene symbol RASSF8
Synonyms (NCBI Gene)
C12orf2HOJ1
Chromosome 12
Chromosome location 12p12.1
Summary This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor supp
miRNA miRNA information provided by mirtarbase database.
415
miRTarBase ID miRNA Experiments Reference
MIRT017153 hsa-miR-335-5p Microarray 18185580
MIRT019781 hsa-miR-375 Microarray 20215506
MIRT020197 hsa-miR-130b-3p Sequencing 20371350
MIRT021333 hsa-miR-9-5p Microarray 17612493
MIRT026013 hsa-miR-148a-3p Sequencing 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
2
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 16189514, 28514442, 32296183, 32814053, 33961781, 35512704
GO:0007165 Process Signal transduction IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608231 13232 ENSG00000123094
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8NHQ8
Protein name Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1)
PDB 2CS4
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00788 RA 1 82 Ras association (RalGDS/AF-6) domain Domain
Tissue specificity TISSUE SPECIFICITY: Widely expressed as a 6.2 kb transcript. A 2.2 kb alternatively spliced transcript is expressed exclusively in testis. {ECO:0000269|PubMed:10951517}.
Sequence
MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPI
ISLNKWGQYASDVQLILRRTGP
SLSERPTSDSVARIPERTLYRQSLPPLAKLRPQIDKSI
KRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSI
EKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQL
KDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKG
EIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKV
TVLPAEPIEIEASHADIEREAPFQSGSLKRPGSSRQLPSNLRILQNPISSGFNPEGIYV
Sequence length 419
Interactions View interactions