Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	11213
Gene name	Interleukin 1 receptor associated kinase 3
Gene symbol	IRAK3
Synonyms (NCBI Gene)	ASRT5IRAKM
Chromosome	12
Chromosome location	12q14.3
Summary	This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophag

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SNP ID	Visualize variation	Clinical significance	Consequence
rs121912630	G>A	Risk-factor	Coding sequence variant, intron variant, stop gained
rs150116809	G>A,T	Risk-factor	Splice donor variant
rs367600113	C>T	Likely-pathogenic	Stop gained, coding sequence variant
rs764674154	->TGA	Likely-pathogenic	Coding sequence variant, stop gained

645

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miRTarBase ID	miRNA	Experiments	Reference
MIRT005808	hsa-miR-155-3p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	20852130
MIRT023129	hsa-miR-124-3p	Microarray	18668037
MIRT051159	hsa-miR-16-5p	CLASH	23622248
MIRT664811	hsa-miR-4486	HITS-CLIP	23824327
MIRT670949	hsa-miR-605-3p	HITS-CLIP	23824327
MIRT664810	hsa-miR-4493	HITS-CLIP	23824327
MIRT649846	hsa-miR-4284	HITS-CLIP	23824327
MIRT649845	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT664809	hsa-miR-4505	HITS-CLIP	23824327
MIRT664808	hsa-miR-5787	HITS-CLIP	23824327
MIRT664807	hsa-miR-3178	HITS-CLIP	23824327
MIRT649844	hsa-miR-7977	HITS-CLIP	23824327
MIRT664806	hsa-miR-6126	HITS-CLIP	23824327
MIRT664805	hsa-miR-4508	HITS-CLIP	23824327
MIRT519130	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT664811	hsa-miR-4486	HITS-CLIP	23824327
MIRT670949	hsa-miR-605-3p	HITS-CLIP	23824327
MIRT664810	hsa-miR-4493	HITS-CLIP	23824327
MIRT649846	hsa-miR-4284	HITS-CLIP	23824327
MIRT649845	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT664809	hsa-miR-4505	HITS-CLIP	23824327
MIRT664808	hsa-miR-5787	HITS-CLIP	23824327
MIRT664807	hsa-miR-3178	HITS-CLIP	23824327
MIRT649844	hsa-miR-7977	HITS-CLIP	23824327
MIRT664806	hsa-miR-6126	HITS-CLIP	23824327
MIRT664805	hsa-miR-4508	HITS-CLIP	23824327
MIRT510122	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT510121	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT510120	hsa-miR-940	HITS-CLIP	23824327
MIRT519130	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT510119	hsa-miR-4514	HITS-CLIP	23824327
MIRT510118	hsa-miR-4692	HITS-CLIP	23824327
MIRT510116	hsa-miR-3937	HITS-CLIP	23824327
MIRT510117	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT510115	hsa-miR-4673	HITS-CLIP	23824327
MIRT664811	hsa-miR-4486	HITS-CLIP	23824327
MIRT664810	hsa-miR-4493	HITS-CLIP	23824327
MIRT649846	hsa-miR-4284	HITS-CLIP	23824327
MIRT649845	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT664809	hsa-miR-4505	HITS-CLIP	23824327
MIRT664808	hsa-miR-5787	HITS-CLIP	23824327
MIRT510113	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT510112	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT510111	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT510110	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT510108	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT510109	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT664807	hsa-miR-3178	HITS-CLIP	23824327
MIRT649844	hsa-miR-7977	HITS-CLIP	23824327
MIRT664806	hsa-miR-6126	HITS-CLIP	23824327
MIRT510107	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT510106	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT510105	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT510104	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT510103	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT510102	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT510101	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT510100	hsa-miR-3689c	HITS-CLIP	23824327
MIRT510099	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT510098	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT510097	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT510096	hsa-miR-3122	HITS-CLIP	23824327
MIRT510095	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT510094	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT510093	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT510092	hsa-miR-1233-5p	HITS-CLIP	23824327
MIRT664805	hsa-miR-4508	HITS-CLIP	23824327
MIRT510122	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT510121	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT510120	hsa-miR-940	HITS-CLIP	23824327
MIRT519130	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT510119	hsa-miR-4514	HITS-CLIP	23824327
MIRT510118	hsa-miR-4692	HITS-CLIP	23824327
MIRT510117	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT510115	hsa-miR-4673	HITS-CLIP	23824327
MIRT510114	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT649846	hsa-miR-4284	HITS-CLIP	23824327
MIRT649845	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT510113	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT510112	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT510111	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT510110	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT510108	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT510109	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT649844	hsa-miR-7977	HITS-CLIP	23824327
MIRT510107	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT510106	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT510105	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT510104	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT510103	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT510102	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT510101	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT510100	hsa-miR-3689c	HITS-CLIP	23824327
MIRT510099	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT510098	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT510097	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT510096	hsa-miR-3122	HITS-CLIP	23824327
MIRT510095	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT510094	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT510093	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT510092	hsa-miR-1233-5p	HITS-CLIP	23824327
MIRT510122	hsa-miR-6808-5p	PAR-CLIP	20371350
MIRT510121	hsa-miR-6893-5p	PAR-CLIP	20371350
MIRT510120	hsa-miR-940	PAR-CLIP	20371350
MIRT510119	hsa-miR-4514	PAR-CLIP	20371350
MIRT510118	hsa-miR-4692	PAR-CLIP	20371350
MIRT510116	hsa-miR-3937	PAR-CLIP	20371350
MIRT510117	hsa-miR-4645-5p	PAR-CLIP	20371350
MIRT510115	hsa-miR-4673	PAR-CLIP	20371350
MIRT510114	hsa-miR-4755-3p	PAR-CLIP	20371350
MIRT510113	hsa-miR-7106-5p	PAR-CLIP	20371350
MIRT510112	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT510111	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT510110	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT510108	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT510109	hsa-miR-6799-5p	PAR-CLIP	20371350
MIRT510107	hsa-miR-30c-1-3p	PAR-CLIP	20371350
MIRT510106	hsa-miR-30c-2-3p	PAR-CLIP	20371350
MIRT510105	hsa-miR-6788-5p	PAR-CLIP	20371350
MIRT510104	hsa-miR-1273h-5p	PAR-CLIP	20371350
MIRT510103	hsa-miR-30b-3p	PAR-CLIP	20371350
MIRT510102	hsa-miR-3689a-3p	PAR-CLIP	20371350
MIRT510101	hsa-miR-3689b-3p	PAR-CLIP	20371350
MIRT510100	hsa-miR-3689c	PAR-CLIP	20371350
MIRT510099	hsa-miR-6779-5p	PAR-CLIP	20371350
MIRT510098	hsa-miR-6780a-5p	PAR-CLIP	20371350
MIRT510097	hsa-miR-450a-1-3p	PAR-CLIP	20371350
MIRT510096	hsa-miR-3122	PAR-CLIP	20371350
MIRT510095	hsa-miR-3913-5p	PAR-CLIP	20371350
MIRT510094	hsa-miR-887-5p	PAR-CLIP	20371350
MIRT510093	hsa-miR-6513-5p	PAR-CLIP	20371350
MIRT510092	hsa-miR-1233-5p	PAR-CLIP	20371350
MIRT510122	hsa-miR-6808-5p	PAR-CLIP	21572407
MIRT510121	hsa-miR-6893-5p	PAR-CLIP	21572407
MIRT510120	hsa-miR-940	PAR-CLIP	21572407
MIRT510119	hsa-miR-4514	PAR-CLIP	21572407
MIRT510118	hsa-miR-4692	PAR-CLIP	21572407
MIRT510116	hsa-miR-3937	PAR-CLIP	21572407
MIRT510117	hsa-miR-4645-5p	PAR-CLIP	21572407
MIRT510115	hsa-miR-4673	PAR-CLIP	21572407
MIRT510114	hsa-miR-4755-3p	PAR-CLIP	21572407
MIRT510113	hsa-miR-7106-5p	PAR-CLIP	21572407
MIRT510112	hsa-miR-149-3p	PAR-CLIP	21572407
MIRT510111	hsa-miR-4728-5p	PAR-CLIP	21572407
MIRT510110	hsa-miR-6785-5p	PAR-CLIP	21572407
MIRT510108	hsa-miR-6883-5p	PAR-CLIP	21572407
MIRT510109	hsa-miR-6799-5p	PAR-CLIP	21572407
MIRT510107	hsa-miR-30c-1-3p	PAR-CLIP	21572407
MIRT510106	hsa-miR-30c-2-3p	PAR-CLIP	21572407
MIRT510105	hsa-miR-6788-5p	PAR-CLIP	21572407
MIRT510104	hsa-miR-1273h-5p	PAR-CLIP	21572407
MIRT510103	hsa-miR-30b-3p	PAR-CLIP	21572407
MIRT510102	hsa-miR-3689a-3p	PAR-CLIP	21572407
MIRT510101	hsa-miR-3689b-3p	PAR-CLIP	21572407
MIRT510100	hsa-miR-3689c	PAR-CLIP	21572407
MIRT510099	hsa-miR-6779-5p	PAR-CLIP	21572407
MIRT510098	hsa-miR-6780a-5p	PAR-CLIP	21572407
MIRT510097	hsa-miR-450a-1-3p	PAR-CLIP	21572407
MIRT510096	hsa-miR-3122	PAR-CLIP	21572407
MIRT510095	hsa-miR-3913-5p	PAR-CLIP	21572407
MIRT510094	hsa-miR-887-5p	PAR-CLIP	21572407
MIRT510093	hsa-miR-6513-5p	PAR-CLIP	21572407
MIRT510092	hsa-miR-1233-5p	PAR-CLIP	21572407
MIRT510122	hsa-miR-6808-5p	PAR-CLIP	23446348
MIRT510121	hsa-miR-6893-5p	PAR-CLIP	23446348
MIRT510120	hsa-miR-940	PAR-CLIP	23446348
MIRT519130	hsa-miR-383-3p	PAR-CLIP	23446348
MIRT510119	hsa-miR-4514	PAR-CLIP	23446348
MIRT510118	hsa-miR-4692	PAR-CLIP	23446348
MIRT510116	hsa-miR-3937	PAR-CLIP	23446348
MIRT510117	hsa-miR-4645-5p	PAR-CLIP	23446348
MIRT510115	hsa-miR-4673	PAR-CLIP	23446348
MIRT510114	hsa-miR-4755-3p	PAR-CLIP	23446348
MIRT510113	hsa-miR-7106-5p	PAR-CLIP	23446348
MIRT510112	hsa-miR-149-3p	PAR-CLIP	23446348
MIRT510111	hsa-miR-4728-5p	PAR-CLIP	23446348
MIRT510110	hsa-miR-6785-5p	PAR-CLIP	23446348
MIRT510108	hsa-miR-6883-5p	PAR-CLIP	23446348
MIRT510109	hsa-miR-6799-5p	PAR-CLIP	23446348
MIRT510107	hsa-miR-30c-1-3p	PAR-CLIP	23446348
MIRT510106	hsa-miR-30c-2-3p	PAR-CLIP	23446348
MIRT510105	hsa-miR-6788-5p	PAR-CLIP	23446348
MIRT510104	hsa-miR-1273h-5p	PAR-CLIP	23446348
MIRT510103	hsa-miR-30b-3p	PAR-CLIP	23446348
MIRT510102	hsa-miR-3689a-3p	PAR-CLIP	23446348
MIRT510101	hsa-miR-3689b-3p	PAR-CLIP	23446348
MIRT510100	hsa-miR-3689c	PAR-CLIP	23446348
MIRT510099	hsa-miR-6779-5p	PAR-CLIP	23446348
MIRT510098	hsa-miR-6780a-5p	PAR-CLIP	23446348
MIRT510097	hsa-miR-450a-1-3p	PAR-CLIP	23446348
MIRT510096	hsa-miR-3122	PAR-CLIP	23446348
MIRT510095	hsa-miR-3913-5p	PAR-CLIP	23446348
MIRT510094	hsa-miR-887-5p	PAR-CLIP	23446348
MIRT510093	hsa-miR-6513-5p	PAR-CLIP	23446348
MIRT510092	hsa-miR-1233-5p	PAR-CLIP	23446348
MIRT510122	hsa-miR-6808-5p	PAR-CLIP	23446348
MIRT510121	hsa-miR-6893-5p	PAR-CLIP	23446348
MIRT510120	hsa-miR-940	PAR-CLIP	23446348
MIRT510119	hsa-miR-4514	PAR-CLIP	23446348
MIRT510118	hsa-miR-4692	PAR-CLIP	23446348
MIRT510116	hsa-miR-3937	PAR-CLIP	23446348
MIRT510117	hsa-miR-4645-5p	PAR-CLIP	23446348
MIRT510115	hsa-miR-4673	PAR-CLIP	23446348
MIRT510114	hsa-miR-4755-3p	PAR-CLIP	23446348
MIRT510113	hsa-miR-7106-5p	PAR-CLIP	23446348
MIRT510112	hsa-miR-149-3p	PAR-CLIP	23446348
MIRT510111	hsa-miR-4728-5p	PAR-CLIP	23446348
MIRT510110	hsa-miR-6785-5p	PAR-CLIP	23446348
MIRT510108	hsa-miR-6883-5p	PAR-CLIP	23446348
MIRT510109	hsa-miR-6799-5p	PAR-CLIP	23446348
MIRT510107	hsa-miR-30c-1-3p	PAR-CLIP	23446348
MIRT510106	hsa-miR-30c-2-3p	PAR-CLIP	23446348
MIRT510105	hsa-miR-6788-5p	PAR-CLIP	23446348
MIRT510104	hsa-miR-1273h-5p	PAR-CLIP	23446348
MIRT510103	hsa-miR-30b-3p	PAR-CLIP	23446348
MIRT510102	hsa-miR-3689a-3p	PAR-CLIP	23446348
MIRT510101	hsa-miR-3689b-3p	PAR-CLIP	23446348
MIRT510100	hsa-miR-3689c	PAR-CLIP	23446348
MIRT510099	hsa-miR-6779-5p	PAR-CLIP	23446348
MIRT510098	hsa-miR-6780a-5p	PAR-CLIP	23446348
MIRT510097	hsa-miR-450a-1-3p	PAR-CLIP	23446348
MIRT510096	hsa-miR-3122	PAR-CLIP	23446348
MIRT510095	hsa-miR-3913-5p	PAR-CLIP	23446348
MIRT510094	hsa-miR-887-5p	PAR-CLIP	23446348
MIRT510093	hsa-miR-6513-5p	PAR-CLIP	23446348
MIRT510092	hsa-miR-1233-5p	PAR-CLIP	23446348
MIRT664811	hsa-miR-4486	HITS-CLIP	23824327
MIRT670949	hsa-miR-605-3p	HITS-CLIP	23824327
MIRT664810	hsa-miR-4493	HITS-CLIP	23824327
MIRT649846	hsa-miR-4284	HITS-CLIP	23824327
MIRT649845	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT664809	hsa-miR-4505	HITS-CLIP	23824327
MIRT664808	hsa-miR-5787	HITS-CLIP	23824327
MIRT664807	hsa-miR-3178	HITS-CLIP	23824327
MIRT649844	hsa-miR-7977	HITS-CLIP	23824327
MIRT664806	hsa-miR-6126	HITS-CLIP	23824327
MIRT664805	hsa-miR-4508	HITS-CLIP	23824327
MIRT519130	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT664811	hsa-miR-4486	HITS-CLIP	23824327
MIRT670949	hsa-miR-605-3p	HITS-CLIP	23824327
MIRT664810	hsa-miR-4493	HITS-CLIP	23824327
MIRT649846	hsa-miR-4284	HITS-CLIP	23824327
MIRT649845	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT664809	hsa-miR-4505	HITS-CLIP	23824327
MIRT664808	hsa-miR-5787	HITS-CLIP	23824327
MIRT664807	hsa-miR-3178	HITS-CLIP	23824327
MIRT649844	hsa-miR-7977	HITS-CLIP	23824327
MIRT664806	hsa-miR-6126	HITS-CLIP	23824327
MIRT664805	hsa-miR-4508	HITS-CLIP	23824327
MIRT510122	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT510121	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT510120	hsa-miR-940	HITS-CLIP	23824327
MIRT519130	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT510119	hsa-miR-4514	HITS-CLIP	23824327
MIRT510118	hsa-miR-4692	HITS-CLIP	23824327
MIRT510116	hsa-miR-3937	HITS-CLIP	23824327
MIRT510117	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT510115	hsa-miR-4673	HITS-CLIP	23824327
MIRT664811	hsa-miR-4486	HITS-CLIP	23824327
MIRT664810	hsa-miR-4493	HITS-CLIP	23824327
MIRT649846	hsa-miR-4284	HITS-CLIP	23824327
MIRT649845	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT664809	hsa-miR-4505	HITS-CLIP	23824327
MIRT664808	hsa-miR-5787	HITS-CLIP	23824327
MIRT510113	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT510112	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT510111	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT510110	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT510108	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT510109	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT664807	hsa-miR-3178	HITS-CLIP	23824327
MIRT649844	hsa-miR-7977	HITS-CLIP	23824327
MIRT664806	hsa-miR-6126	HITS-CLIP	23824327
MIRT510107	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT510106	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT510105	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT510104	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT510103	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT510102	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT510101	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT510100	hsa-miR-3689c	HITS-CLIP	23824327
MIRT510099	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT510098	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT510097	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT510096	hsa-miR-3122	HITS-CLIP	23824327
MIRT510095	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT510094	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT510093	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT510092	hsa-miR-1233-5p	HITS-CLIP	23824327
MIRT664805	hsa-miR-4508	HITS-CLIP	23824327
MIRT510122	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT510121	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT510120	hsa-miR-940	HITS-CLIP	23824327
MIRT519130	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT510119	hsa-miR-4514	HITS-CLIP	23824327
MIRT510118	hsa-miR-4692	HITS-CLIP	23824327
MIRT510117	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT510115	hsa-miR-4673	HITS-CLIP	23824327
MIRT510114	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT649846	hsa-miR-4284	HITS-CLIP	23824327
MIRT649845	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT510113	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT510112	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT510111	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT510110	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT510108	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT510109	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT649844	hsa-miR-7977	HITS-CLIP	23824327
MIRT510107	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT510106	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT510105	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT510104	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT510103	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT510102	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT510101	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT510100	hsa-miR-3689c	HITS-CLIP	23824327
MIRT510099	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT510098	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT510097	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT510096	hsa-miR-3122	HITS-CLIP	23824327
MIRT510095	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT510094	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT510093	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT510092	hsa-miR-1233-5p	HITS-CLIP	23824327
MIRT510122	hsa-miR-6808-5p	PAR-CLIP	20371350
MIRT510121	hsa-miR-6893-5p	PAR-CLIP	20371350
MIRT510120	hsa-miR-940	PAR-CLIP	20371350
MIRT510119	hsa-miR-4514	PAR-CLIP	20371350
MIRT510118	hsa-miR-4692	PAR-CLIP	20371350
MIRT510116	hsa-miR-3937	PAR-CLIP	20371350
MIRT510117	hsa-miR-4645-5p	PAR-CLIP	20371350
MIRT510115	hsa-miR-4673	PAR-CLIP	20371350
MIRT510114	hsa-miR-4755-3p	PAR-CLIP	20371350
MIRT510113	hsa-miR-7106-5p	PAR-CLIP	20371350
MIRT510112	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT510111	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT510110	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT510108	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT510109	hsa-miR-6799-5p	PAR-CLIP	20371350
MIRT510107	hsa-miR-30c-1-3p	PAR-CLIP	20371350
MIRT510106	hsa-miR-30c-2-3p	PAR-CLIP	20371350
MIRT510105	hsa-miR-6788-5p	PAR-CLIP	20371350
MIRT510104	hsa-miR-1273h-5p	PAR-CLIP	20371350
MIRT510103	hsa-miR-30b-3p	PAR-CLIP	20371350
MIRT510102	hsa-miR-3689a-3p	PAR-CLIP	20371350
MIRT510101	hsa-miR-3689b-3p	PAR-CLIP	20371350
MIRT510100	hsa-miR-3689c	PAR-CLIP	20371350
MIRT510099	hsa-miR-6779-5p	PAR-CLIP	20371350
MIRT510098	hsa-miR-6780a-5p	PAR-CLIP	20371350
MIRT510097	hsa-miR-450a-1-3p	PAR-CLIP	20371350
MIRT510096	hsa-miR-3122	PAR-CLIP	20371350
MIRT510095	hsa-miR-3913-5p	PAR-CLIP	20371350
MIRT510094	hsa-miR-887-5p	PAR-CLIP	20371350
MIRT510093	hsa-miR-6513-5p	PAR-CLIP	20371350
MIRT510092	hsa-miR-1233-5p	PAR-CLIP	20371350
MIRT510122	hsa-miR-6808-5p	PAR-CLIP	21572407
MIRT510121	hsa-miR-6893-5p	PAR-CLIP	21572407
MIRT510120	hsa-miR-940	PAR-CLIP	21572407
MIRT510119	hsa-miR-4514	PAR-CLIP	21572407
MIRT510118	hsa-miR-4692	PAR-CLIP	21572407
MIRT510116	hsa-miR-3937	PAR-CLIP	21572407
MIRT510117	hsa-miR-4645-5p	PAR-CLIP	21572407
MIRT510115	hsa-miR-4673	PAR-CLIP	21572407
MIRT510114	hsa-miR-4755-3p	PAR-CLIP	21572407
MIRT510113	hsa-miR-7106-5p	PAR-CLIP	21572407
MIRT510112	hsa-miR-149-3p	PAR-CLIP	21572407
MIRT510111	hsa-miR-4728-5p	PAR-CLIP	21572407
MIRT510110	hsa-miR-6785-5p	PAR-CLIP	21572407
MIRT510108	hsa-miR-6883-5p	PAR-CLIP	21572407
MIRT510109	hsa-miR-6799-5p	PAR-CLIP	21572407
MIRT510107	hsa-miR-30c-1-3p	PAR-CLIP	21572407
MIRT510106	hsa-miR-30c-2-3p	PAR-CLIP	21572407
MIRT510105	hsa-miR-6788-5p	PAR-CLIP	21572407
MIRT510104	hsa-miR-1273h-5p	PAR-CLIP	21572407
MIRT510103	hsa-miR-30b-3p	PAR-CLIP	21572407
MIRT510102	hsa-miR-3689a-3p	PAR-CLIP	21572407
MIRT510101	hsa-miR-3689b-3p	PAR-CLIP	21572407
MIRT510100	hsa-miR-3689c	PAR-CLIP	21572407
MIRT510099	hsa-miR-6779-5p	PAR-CLIP	21572407
MIRT510098	hsa-miR-6780a-5p	PAR-CLIP	21572407
MIRT510097	hsa-miR-450a-1-3p	PAR-CLIP	21572407
MIRT510096	hsa-miR-3122	PAR-CLIP	21572407
MIRT510095	hsa-miR-3913-5p	PAR-CLIP	21572407
MIRT510094	hsa-miR-887-5p	PAR-CLIP	21572407
MIRT510093	hsa-miR-6513-5p	PAR-CLIP	21572407
MIRT510092	hsa-miR-1233-5p	PAR-CLIP	21572407
MIRT510122	hsa-miR-6808-5p	PAR-CLIP	23446348
MIRT510121	hsa-miR-6893-5p	PAR-CLIP	23446348
MIRT510120	hsa-miR-940	PAR-CLIP	23446348
MIRT519130	hsa-miR-383-3p	PAR-CLIP	23446348
MIRT510119	hsa-miR-4514	PAR-CLIP	23446348
MIRT510118	hsa-miR-4692	PAR-CLIP	23446348
MIRT510116	hsa-miR-3937	PAR-CLIP	23446348
MIRT510117	hsa-miR-4645-5p	PAR-CLIP	23446348
MIRT510115	hsa-miR-4673	PAR-CLIP	23446348
MIRT510114	hsa-miR-4755-3p	PAR-CLIP	23446348
MIRT510113	hsa-miR-7106-5p	PAR-CLIP	23446348
MIRT510112	hsa-miR-149-3p	PAR-CLIP	23446348
MIRT510111	hsa-miR-4728-5p	PAR-CLIP	23446348
MIRT510110	hsa-miR-6785-5p	PAR-CLIP	23446348
MIRT510108	hsa-miR-6883-5p	PAR-CLIP	23446348
MIRT510109	hsa-miR-6799-5p	PAR-CLIP	23446348
MIRT510107	hsa-miR-30c-1-3p	PAR-CLIP	23446348
MIRT510106	hsa-miR-30c-2-3p	PAR-CLIP	23446348
MIRT510105	hsa-miR-6788-5p	PAR-CLIP	23446348
MIRT510104	hsa-miR-1273h-5p	PAR-CLIP	23446348
MIRT510103	hsa-miR-30b-3p	PAR-CLIP	23446348
MIRT510102	hsa-miR-3689a-3p	PAR-CLIP	23446348
MIRT510101	hsa-miR-3689b-3p	PAR-CLIP	23446348
MIRT510100	hsa-miR-3689c	PAR-CLIP	23446348
MIRT510099	hsa-miR-6779-5p	PAR-CLIP	23446348
MIRT510098	hsa-miR-6780a-5p	PAR-CLIP	23446348
MIRT510097	hsa-miR-450a-1-3p	PAR-CLIP	23446348
MIRT510096	hsa-miR-3122	PAR-CLIP	23446348
MIRT510095	hsa-miR-3913-5p	PAR-CLIP	23446348
MIRT510094	hsa-miR-887-5p	PAR-CLIP	23446348
MIRT510093	hsa-miR-6513-5p	PAR-CLIP	23446348
MIRT510092	hsa-miR-1233-5p	PAR-CLIP	23446348
MIRT510122	hsa-miR-6808-5p	PAR-CLIP	23446348
MIRT510121	hsa-miR-6893-5p	PAR-CLIP	23446348
MIRT510120	hsa-miR-940	PAR-CLIP	23446348
MIRT510119	hsa-miR-4514	PAR-CLIP	23446348
MIRT510118	hsa-miR-4692	PAR-CLIP	23446348
MIRT510116	hsa-miR-3937	PAR-CLIP	23446348
MIRT510117	hsa-miR-4645-5p	PAR-CLIP	23446348
MIRT510115	hsa-miR-4673	PAR-CLIP	23446348
MIRT510114	hsa-miR-4755-3p	PAR-CLIP	23446348
MIRT510113	hsa-miR-7106-5p	PAR-CLIP	23446348
MIRT510112	hsa-miR-149-3p	PAR-CLIP	23446348
MIRT510111	hsa-miR-4728-5p	PAR-CLIP	23446348
MIRT510110	hsa-miR-6785-5p	PAR-CLIP	23446348
MIRT510108	hsa-miR-6883-5p	PAR-CLIP	23446348
MIRT510109	hsa-miR-6799-5p	PAR-CLIP	23446348
MIRT510107	hsa-miR-30c-1-3p	PAR-CLIP	23446348
MIRT510106	hsa-miR-30c-2-3p	PAR-CLIP	23446348
MIRT510105	hsa-miR-6788-5p	PAR-CLIP	23446348
MIRT510104	hsa-miR-1273h-5p	PAR-CLIP	23446348
MIRT510103	hsa-miR-30b-3p	PAR-CLIP	23446348
MIRT510102	hsa-miR-3689a-3p	PAR-CLIP	23446348
MIRT510101	hsa-miR-3689b-3p	PAR-CLIP	23446348
MIRT510100	hsa-miR-3689c	PAR-CLIP	23446348
MIRT510099	hsa-miR-6779-5p	PAR-CLIP	23446348
MIRT510098	hsa-miR-6780a-5p	PAR-CLIP	23446348
MIRT510097	hsa-miR-450a-1-3p	PAR-CLIP	23446348
MIRT510096	hsa-miR-3122	PAR-CLIP	23446348
MIRT510095	hsa-miR-3913-5p	PAR-CLIP	23446348
MIRT510094	hsa-miR-887-5p	PAR-CLIP	23446348
MIRT510093	hsa-miR-6513-5p	PAR-CLIP	23446348
MIRT510092	hsa-miR-1233-5p	PAR-CLIP	23446348
MIRT1070479	hsa-miR-1183	CLIP-seq
MIRT1070480	hsa-miR-1200	CLIP-seq
MIRT1070481	hsa-miR-1254	CLIP-seq
MIRT1070482	hsa-miR-1255a	CLIP-seq
MIRT1070483	hsa-miR-1255b	CLIP-seq
MIRT1070484	hsa-miR-1286	CLIP-seq
MIRT1070485	hsa-miR-1324	CLIP-seq
MIRT1070486	hsa-miR-143	CLIP-seq
MIRT1070487	hsa-miR-1827	CLIP-seq
MIRT1070488	hsa-miR-24	CLIP-seq
MIRT1070489	hsa-miR-3116	CLIP-seq
MIRT1070490	hsa-miR-3130-3p	CLIP-seq
MIRT1070491	hsa-miR-3137	CLIP-seq
MIRT1070492	hsa-miR-3200-3p	CLIP-seq
MIRT1070493	hsa-miR-3612	CLIP-seq
MIRT1070494	hsa-miR-3662	CLIP-seq
MIRT1070495	hsa-miR-3684	CLIP-seq
MIRT1070496	hsa-miR-376c	CLIP-seq
MIRT1070497	hsa-miR-3943	CLIP-seq
MIRT1070498	hsa-miR-4267	CLIP-seq
MIRT1070499	hsa-miR-4297	CLIP-seq
MIRT1070500	hsa-miR-4307	CLIP-seq
MIRT1070501	hsa-miR-4323	CLIP-seq
MIRT1070502	hsa-miR-4324	CLIP-seq
MIRT1070503	hsa-miR-4423-5p	CLIP-seq
MIRT1070504	hsa-miR-4436a	CLIP-seq
MIRT1070505	hsa-miR-4468	CLIP-seq
MIRT1070506	hsa-miR-4537	CLIP-seq
MIRT1070507	hsa-miR-4666-5p	CLIP-seq
MIRT1070508	hsa-miR-4683	CLIP-seq
MIRT1070509	hsa-miR-4722-3p	CLIP-seq
MIRT1070510	hsa-miR-4722-5p	CLIP-seq
MIRT1070511	hsa-miR-4746-3p	CLIP-seq
MIRT1070512	hsa-miR-4768-3p	CLIP-seq
MIRT1070513	hsa-miR-4770	CLIP-seq
MIRT1070514	hsa-miR-4777-5p	CLIP-seq
MIRT1070515	hsa-miR-4786-5p	CLIP-seq
MIRT1070516	hsa-miR-4792	CLIP-seq
MIRT1070517	hsa-miR-4793-3p	CLIP-seq
MIRT1070518	hsa-miR-4793-5p	CLIP-seq
MIRT1070519	hsa-miR-487a	CLIP-seq
MIRT1070520	hsa-miR-502-5p	CLIP-seq
MIRT1070521	hsa-miR-508-5p	CLIP-seq
MIRT1070522	hsa-miR-518d-5p	CLIP-seq
MIRT1070523	hsa-miR-519b-5p	CLIP-seq
MIRT1070524	hsa-miR-519c-5p	CLIP-seq
MIRT1070525	hsa-miR-520c-5p	CLIP-seq
MIRT1070526	hsa-miR-520f	CLIP-seq
MIRT1070527	hsa-miR-526a	CLIP-seq
MIRT1070528	hsa-miR-539	CLIP-seq
MIRT1070529	hsa-miR-544b	CLIP-seq
MIRT1070530	hsa-miR-580	CLIP-seq
MIRT1070531	hsa-miR-650	CLIP-seq
MIRT1070532	hsa-miR-766	CLIP-seq
MIRT1070533	hsa-miR-889	CLIP-seq
MIRT1070534	hsa-miR-1224-3p	CLIP-seq
MIRT1070535	hsa-miR-1260	CLIP-seq
MIRT1070536	hsa-miR-1260b	CLIP-seq
MIRT1070537	hsa-miR-1280	CLIP-seq
MIRT1070485	hsa-miR-1324	CLIP-seq
MIRT1070538	hsa-miR-139-5p	CLIP-seq
MIRT1070539	hsa-miR-1908	CLIP-seq
MIRT1070540	hsa-miR-2114	CLIP-seq
MIRT1070541	hsa-miR-3174	CLIP-seq
MIRT1070542	hsa-miR-3613-3p	CLIP-seq
MIRT1070543	hsa-miR-3677-5p	CLIP-seq
MIRT1070544	hsa-miR-425	CLIP-seq
MIRT1070545	hsa-miR-4272	CLIP-seq
MIRT1070546	hsa-miR-4502	CLIP-seq
MIRT1070547	hsa-miR-4684-5p	CLIP-seq
MIRT1070548	hsa-miR-4700-3p	CLIP-seq
MIRT1070549	hsa-miR-4762-3p	CLIP-seq
MIRT1070550	hsa-miR-4767	CLIP-seq
MIRT1070551	hsa-miR-4790-3p	CLIP-seq
MIRT1070552	hsa-miR-4797-5p	CLIP-seq
MIRT1070553	hsa-miR-548c-3p	CLIP-seq
MIRT1070554	hsa-miR-566	CLIP-seq
MIRT1070555	hsa-miR-582-5p	CLIP-seq
MIRT1070556	hsa-miR-585	CLIP-seq
MIRT1070557	hsa-miR-633	CLIP-seq
MIRT1070558	hsa-miR-663	CLIP-seq
MIRT2017328	hsa-miR-1270	CLIP-seq
MIRT2017329	hsa-miR-185	CLIP-seq
MIRT2017330	hsa-miR-3125	CLIP-seq
MIRT2017331	hsa-miR-3189-3p	CLIP-seq
MIRT1070542	hsa-miR-3613-3p	CLIP-seq
MIRT2017332	hsa-miR-3647-3p	CLIP-seq
MIRT2017333	hsa-miR-3714	CLIP-seq
MIRT2017334	hsa-miR-3916	CLIP-seq
MIRT2017335	hsa-miR-4306	CLIP-seq
MIRT2017336	hsa-miR-432	CLIP-seq
MIRT2017337	hsa-miR-4448	CLIP-seq
MIRT2017338	hsa-miR-4531	CLIP-seq
MIRT2017339	hsa-miR-4644	CLIP-seq
MIRT1070553	hsa-miR-548c-3p	CLIP-seq
MIRT2017340	hsa-miR-620	CLIP-seq
MIRT2249220	hsa-miR-1227	CLIP-seq
MIRT2249221	hsa-miR-1245	CLIP-seq
MIRT1070481	hsa-miR-1254	CLIP-seq
MIRT1070482	hsa-miR-1255a	CLIP-seq
MIRT1070483	hsa-miR-1255b	CLIP-seq
MIRT2249222	hsa-miR-1266	CLIP-seq
MIRT2249223	hsa-miR-1267	CLIP-seq
MIRT2249224	hsa-miR-1305	CLIP-seq
MIRT1070485	hsa-miR-1324	CLIP-seq
MIRT1070489	hsa-miR-3116	CLIP-seq
MIRT2249225	hsa-miR-3127-3p	CLIP-seq
MIRT2249226	hsa-miR-3148	CLIP-seq
MIRT2249227	hsa-miR-3545-3p	CLIP-seq
MIRT2249228	hsa-miR-3616-5p	CLIP-seq
MIRT2017332	hsa-miR-3647-3p	CLIP-seq
MIRT2249229	hsa-miR-3647-5p	CLIP-seq
MIRT2249230	hsa-miR-3664-3p	CLIP-seq
MIRT2249231	hsa-miR-4252	CLIP-seq
MIRT2249232	hsa-miR-4282	CLIP-seq
MIRT2249233	hsa-miR-4420	CLIP-seq
MIRT2249234	hsa-miR-4484	CLIP-seq
MIRT2249235	hsa-miR-4518	CLIP-seq
MIRT2249236	hsa-miR-4539	CLIP-seq
MIRT2249237	hsa-miR-4724-5p	CLIP-seq
MIRT2249238	hsa-miR-4747-5p	CLIP-seq
MIRT1070512	hsa-miR-4768-3p	CLIP-seq
MIRT2249239	hsa-miR-4789-3p	CLIP-seq
MIRT1070517	hsa-miR-4793-3p	CLIP-seq
MIRT1070521	hsa-miR-508-5p	CLIP-seq
MIRT2249240	hsa-miR-548an	CLIP-seq
MIRT2249241	hsa-miR-573	CLIP-seq
MIRT2249242	hsa-miR-605	CLIP-seq
MIRT2249243	hsa-miR-635	CLIP-seq
MIRT2249244	hsa-miR-653	CLIP-seq
MIRT2249245	hsa-miR-660	CLIP-seq
MIRT2249246	hsa-miR-668	CLIP-seq
MIRT1070532	hsa-miR-766	CLIP-seq
MIRT2249247	hsa-miR-873	CLIP-seq
MIRT2249248	hsa-miR-875-3p	CLIP-seq
MIRT1070481	hsa-miR-1254	CLIP-seq
MIRT1070489	hsa-miR-3116	CLIP-seq
MIRT1070539	hsa-miR-1908	CLIP-seq
MIRT1070542	hsa-miR-3613-3p	CLIP-seq
MIRT1070543	hsa-miR-3677-5p	CLIP-seq
MIRT1070547	hsa-miR-4684-5p	CLIP-seq
MIRT1070550	hsa-miR-4767	CLIP-seq
MIRT1070553	hsa-miR-548c-3p	CLIP-seq
MIRT1070554	hsa-miR-566	CLIP-seq
MIRT1070556	hsa-miR-585	CLIP-seq
MIRT1070558	hsa-miR-663	CLIP-seq
MIRT2552769	hsa-miR-1185	CLIP-seq
MIRT1070481	hsa-miR-1254	CLIP-seq
MIRT1070482	hsa-miR-1255a	CLIP-seq
MIRT1070483	hsa-miR-1255b	CLIP-seq
MIRT2017329	hsa-miR-185	CLIP-seq
MIRT1070539	hsa-miR-1908	CLIP-seq
MIRT2552770	hsa-miR-204	CLIP-seq
MIRT2552771	hsa-miR-2052	CLIP-seq
MIRT2552772	hsa-miR-211	CLIP-seq
MIRT1070540	hsa-miR-2114	CLIP-seq
MIRT2552773	hsa-miR-219-5p	CLIP-seq
MIRT1070489	hsa-miR-3116	CLIP-seq
MIRT2552774	hsa-miR-3134	CLIP-seq
MIRT2552775	hsa-miR-323-3p	CLIP-seq
MIRT2552776	hsa-miR-3605-5p	CLIP-seq
MIRT1070542	hsa-miR-3613-3p	CLIP-seq
MIRT1070543	hsa-miR-3677-5p	CLIP-seq
MIRT2552777	hsa-miR-3679-5p	CLIP-seq
MIRT2552778	hsa-miR-371-5p	CLIP-seq
MIRT2552779	hsa-miR-371b-5p	CLIP-seq
MIRT2249231	hsa-miR-4252	CLIP-seq
MIRT2017335	hsa-miR-4306	CLIP-seq
MIRT2552780	hsa-miR-4445	CLIP-seq
MIRT2552781	hsa-miR-4464	CLIP-seq
MIRT2552782	hsa-miR-4477b	CLIP-seq
MIRT2552783	hsa-miR-4534	CLIP-seq
MIRT2017339	hsa-miR-4644	CLIP-seq
MIRT1070547	hsa-miR-4684-5p	CLIP-seq
MIRT2552784	hsa-miR-4748	CLIP-seq
MIRT1070550	hsa-miR-4767	CLIP-seq
MIRT2552785	hsa-miR-4782-3p	CLIP-seq
MIRT1070517	hsa-miR-4793-3p	CLIP-seq
MIRT2552786	hsa-miR-508-3p	CLIP-seq
MIRT1070521	hsa-miR-508-5p	CLIP-seq
MIRT1070553	hsa-miR-548c-3p	CLIP-seq
MIRT1070554	hsa-miR-566	CLIP-seq
MIRT1070556	hsa-miR-585	CLIP-seq
MIRT2552787	hsa-miR-647	CLIP-seq
MIRT1070558	hsa-miR-663	CLIP-seq
MIRT1070532	hsa-miR-766	CLIP-seq
MIRT1070539	hsa-miR-1908	CLIP-seq
MIRT1070540	hsa-miR-2114	CLIP-seq
MIRT1070542	hsa-miR-3613-3p	CLIP-seq
MIRT1070543	hsa-miR-3677-5p	CLIP-seq
MIRT1070547	hsa-miR-4684-5p	CLIP-seq
MIRT1070550	hsa-miR-4767	CLIP-seq
MIRT1070553	hsa-miR-548c-3p	CLIP-seq
MIRT1070554	hsa-miR-566	CLIP-seq
MIRT1070556	hsa-miR-585	CLIP-seq
MIRT1070558	hsa-miR-663	CLIP-seq

Show/Hide all (72)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000287	Function	Magnesium ion binding	IDA	10383454
GO:0000287	Function	Magnesium ion binding	IEA
GO:0001819	Process	Positive regulation of cytokine production	IEA
GO:0001960	Process	Negative regulation of cytokine-mediated signaling pathway	IC	12150927
GO:0001960	Process	Negative regulation of cytokine-mediated signaling pathway	IEA
GO:0002684	Process	Positive regulation of immune system process	IEA
GO:0002755	Process	MyD88-dependent toll-like receptor signaling pathway	TAS	10383454
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	10383454
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	29686383, 32296183
GO:0005524	Function	ATP binding	IDA	10383454
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	17379480
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	17379480
GO:0005737	Component	Cytoplasm	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0006468	Process	Protein phosphorylation	IDA	10383454
GO:0007165	Process	Signal transduction	IEA
GO:0008063	Process	Toll signaling pathway	IBA
GO:0009615	Process	Response to virus	IC	12150927
GO:0009615	Process	Response to virus	IEA
GO:0010933	Process	Positive regulation of macrophage tolerance induction	IEA
GO:0010933	Process	Positive regulation of macrophage tolerance induction	ISS	12150927
GO:0010936	Process	Negative regulation of macrophage cytokine production	IEA
GO:0010936	Process	Negative regulation of macrophage cytokine production	ISS	12150927
GO:0019221	Process	Cytokine-mediated signaling pathway	IEA
GO:0019221	Process	Cytokine-mediated signaling pathway	ISS
GO:0019901	Function	Protein kinase binding	IPI	33238146
GO:0031663	Process	Lipopolysaccharide-mediated signaling pathway	IBA
GO:0031663	Process	Lipopolysaccharide-mediated signaling pathway	IMP	18156187
GO:0032494	Process	Response to peptidoglycan	IEA
GO:0032494	Process	Response to peptidoglycan	ISS	12150927
GO:0032496	Process	Response to lipopolysaccharide	IEA
GO:0032496	Process	Response to lipopolysaccharide	ISS	12150927
GO:0032695	Process	Negative regulation of interleukin-12 production	IEA
GO:0032695	Process	Negative regulation of interleukin-12 production	IMP	18156187
GO:0032695	Process	Negative regulation of interleukin-12 production	ISS	12150927
GO:0032715	Process	Negative regulation of interleukin-6 production	IEA
GO:0032715	Process	Negative regulation of interleukin-6 production	IMP	18156187
GO:0032715	Process	Negative regulation of interleukin-6 production	ISS	12150927
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IEA
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IMP	15728517
GO:0034122	Process	Negative regulation of toll-like receptor signaling pathway	IEA
GO:0034122	Process	Negative regulation of toll-like receptor signaling pathway	ISS	12150927
GO:0035556	Process	Intracellular signal transduction	IBA
GO:0042177	Process	Negative regulation of protein catabolic process	IEA
GO:0042177	Process	Negative regulation of protein catabolic process	IMP	17379480
GO:0042803	Function	Protein homodimerization activity	IDA	33238146
GO:0042803	Function	Protein homodimerization activity	IPI	10383454
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IBA
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IMP	10383454
GO:0043242	Process	Negative regulation of protein-containing complex disassembly	IMP	12150927
GO:0043244	Process	Regulation of protein-containing complex disassembly	IEA
GO:0043244	Process	Regulation of protein-containing complex disassembly	ISS
GO:0043330	Process	Response to exogenous dsRNA	IEA
GO:0043330	Process	Response to exogenous dsRNA	ISS	12150927
GO:0043409	Process	Negative regulation of MAPK cascade	IEA
GO:0043409	Process	Negative regulation of MAPK cascade	IMP	17379480
GO:0045088	Process	Regulation of innate immune response	IEA
GO:0045824	Process	Negative regulation of innate immune response	IEA
GO:0045824	Process	Negative regulation of innate immune response	ISS	12150927
GO:0046982	Function	Protein heterodimerization activity	IPI	10383454
GO:0070498	Process	Interleukin-1-mediated signaling pathway	IBA
GO:0070498	Process	Interleukin-1-mediated signaling pathway	IEA
GO:0070498	Process	Interleukin-1-mediated signaling pathway	IEA
GO:0070498	Process	Interleukin-1-mediated signaling pathway	IMP	10383454
GO:0070555	Process	Response to interleukin-1	IMP	10383454

MIM	HGNC	e!Ensembl
604459	17020	ENSG00000090376

Q9Y616

Protein name

Interleukin-1 receptor-associated kinase 3 (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) (Inactive IL-1 receptor-associated kinase 3)

Protein function

Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors (PubMed:10383454, PubMed:29686383). Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling c

PDB

5UKE , 6RUU , 6ZIW

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00531	Death	26 → 106	Death domain	Domain
PF00069	Pkinase	165 → 443	Protein kinase domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in eosinophils, dendritic cells and/or monocytes (at protein level) (PubMed:29686383). Expressed predominantly in peripheral blood lymphocytes (PubMed:10383454). {ECO:0000269|PubMed:10383454, ECO:0000269|PubMed:29686383}.

Sequence

MAGNCGARGALSAHTLLFDLPPALLGELCAVLDSCDGALGWRGLAERLSSSWLDVRHIEK
YVDQGKSGTRELLWSWAQKNKTIGDLLQVLQEMGHRRAIHLITNYGAVLSPSEKSYQEGG
FPNILFKETANVTVDNVLIPEHNEKGILLKSSISFQNIIEGTRNFHKDFLIGEGEIFEVY
RVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFTETEKFCLI
YPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANIL
LDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSF
GIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFC
LAGRCAATRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVE
DDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSSCE
ESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESSCSSKFSWDEYEQYKKE

Sequence length

596

Interactions

View interactions

	KEGG		Reactome
	Neurotrophin signaling pathway		MyD88:MAL(TIRAP) cascade initiated on plasma membrane Interleukin-1 signaling

Show/Hide Unknown Diseases (14)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Benign	rs56001649, rs138190862	RCV005907987 RCV005905899
Asthma-related traits, susceptibility to, 5	risk factor	rs121912630, rs150116809	RCV000005873 RCV000005874
Familial cancer of breast	Benign	rs138190862	RCV005905898
Hirschsprung disease, susceptibility to, 1	Likely benign	rs776951445	RCV000201309
IRAK3-related disorder	Likely benign; Benign	rs376280813, rs11465987, rs535521918, rs11465988, rs146120640, rs368882241, rs777458740, rs1152888, rs11465972, rs34682166, rs138190862	RCV003912149 RCV003939639 RCV003961373 RCV003914504 RCV003936938 RCV003922184 RCV003934231 RCV003981844 RCV003971728 RCV003959867 RCV003910554
Lung cancer	Benign	rs56001649	RCV005907993
Malignant tumor of esophagus	Benign	rs56001649	RCV005907988
Melanoma	Benign	rs56001649	RCV005907992
Multisystem inflammatory syndrome in children	Likely benign	rs776951445	RCV001778770
Ovarian serous cystadenocarcinoma	risk factor; Benign	rs150116809, rs56001649, rs138190862	RCV005887323 RCV005907990 RCV005905900
Sarcoma	Benign	rs56001649	RCV005907989
Susceptibility to severe COVID-19	Likely risk allele	rs768767136	RCV003120370
Thyroid cancer, nonmedullary, 1	Benign	rs56001649	RCV005907991
Uterine corpus endometrial carcinoma	Benign	rs56001649	RCV005907994

Show/Hide Text Mining Associations (49)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Acute Lung Injury	Associate	21297081, 22742663
Alzheimer Disease	Associate	32755048
Aneurysm Ruptured	Associate	33990177
Aortic Dissection	Associate	35178459
Asthma	Associate	17503328, 33156843, 37029363
Asthma	Stimulate	28223794
Carcinoma Hepatocellular	Associate	25852282
Cardiomyopathy Hypertrophic	Associate	38277535
Cerebral Infarction	Associate	35432334
Colitis Lymphocytic	Stimulate	25232259
Colitis Ulcerative	Stimulate	25232259, 26462859
Colitis Ulcerative	Associate	36419192
Coronavirus Infections	Stimulate	28118607
COVID 19	Associate	33156843, 34975885
Crohn Disease	Associate	26462859
Endometriosis	Associate	40187212
Glioblastoma	Associate	26956052
Glioma	Associate	19423540
Healthcare Associated Pneumonia	Associate	25481771
Heart Arrest	Stimulate	27260481
Hemorrhage	Associate	23468366
Inflammation	Associate	17503328, 22393448, 25481771, 33156843, 34248968, 37029363
Inflammation	Inhibit	22272346
Lung Neoplasms	Associate	25481771
Malaria Cerebral	Associate	36782344
Melanoma	Associate	33373316
Metabolic Syndrome	Associate	22272346, 37138862
Myocardial Infarction	Associate	35432334
Neoplasms	Associate	25852282, 31659097, 33373316, 40755754
Obesity	Inhibit	22272346
Obesity	Associate	31900140
Osteoarthritis	Associate	33658057, 37138862, 39849508
Osteosarcoma	Associate	31690262
Oto palato digital syndrome type 2	Associate	33328540
Pneumonia	Associate	37029363
Pulmonary Disease Chronic Obstructive	Stimulate	28223794
Pulmonary Disease Chronic Obstructive	Associate	36655999
Sarcoidosis	Stimulate	27402699
Sepsis	Associate	21297081
ST Elevation Myocardial Infarction	Associate	26025919
Status Asthmaticus	Stimulate	22154382
Stroke	Associate	23468366
Subarachnoid Hemorrhage	Associate	33990177
Tuberculosis	Stimulate	25887604
Tuberculosis	Associate	33328540
Tuberculosis Pulmonary	Associate	28835201
Urinary Bladder Neoplasms	Associate	40755754
Weight Gain	Associate	31900140
Weight Loss	Stimulate	22272346

IRAK3 (interleukin 1 receptor associated kinase 3)