Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	11186
Gene name Gene Name - the full gene name approved by the HGNC.	Ras association domain family member 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RASSF1
Synonyms (NCBI Gene) Gene synonyms aliases	123F2, NORE2A, RASSF1A, RDA32, REH3P21
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3p21.31
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of thi

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miRTarBase ID	miRNA	Experiments	Reference
MIRT006022	hsa-miR-373-3p	Luciferase reporter assay, qRT-PCR, Western blot	21086164
MIRT006022	hsa-miR-373-3p	Luciferase reporter assay, qRT-PCR, Western blot	21086164
MIRT006022	hsa-miR-373-3p	Luciferase reporter assay, qRT-PCR, Western blot	21086164
MIRT006022	hsa-miR-373-3p	Luciferase reporter assay, qRT-PCR, Western blot	21086164
MIRT006022	hsa-miR-373-3p	Luciferase reporter assay, qRT-PCR, Western blot	21086164
MIRT006022	hsa-miR-373-3p	Luciferase reporter assay, qRT-PCR, Western blot	21086164
MIRT016088	hsa-miR-744-5p	Sequencing	20371350
MIRT020199	hsa-miR-130b-3p	Sequencing	20371350
MIRT022310	hsa-miR-124-3p	Microarray	18668037
MIRT023590	hsa-miR-1-3p	Microarray	18668037
MIRT031097	hsa-miR-19b-3p	Sequencing	20371350
MIRT045120	hsa-miR-186-5p	CLASH	23622248
MIRT1292630	hsa-miR-1285	CLIP-seq
MIRT1292631	hsa-miR-2117	CLIP-seq
MIRT1292632	hsa-miR-3138	CLIP-seq
MIRT1292633	hsa-miR-3187-5p	CLIP-seq
MIRT1292634	hsa-miR-326	CLIP-seq
MIRT1292635	hsa-miR-330-5p	CLIP-seq
MIRT1292636	hsa-miR-378g	CLIP-seq
MIRT1292637	hsa-miR-4270	CLIP-seq
MIRT1292638	hsa-miR-4273	CLIP-seq
MIRT1292639	hsa-miR-4437	CLIP-seq
MIRT1292640	hsa-miR-4441	CLIP-seq
MIRT1292641	hsa-miR-4486	CLIP-seq
MIRT1292642	hsa-miR-4674	CLIP-seq
MIRT1292643	hsa-miR-4794	CLIP-seq
MIRT1292644	hsa-miR-552	CLIP-seq
MIRT1292645	hsa-miR-612	CLIP-seq
MIRT1292646	hsa-miR-619	CLIP-seq
MIRT1292647	hsa-miR-639	CLIP-seq
MIRT1292648	hsa-miR-10a	CLIP-seq
MIRT1292649	hsa-miR-10b	CLIP-seq
MIRT1292650	hsa-miR-1182	CLIP-seq
MIRT1292651	hsa-miR-1207-3p	CLIP-seq
MIRT1292652	hsa-miR-1224-5p	CLIP-seq
MIRT1292653	hsa-miR-1291	CLIP-seq
MIRT1292654	hsa-miR-146b-3p	CLIP-seq
MIRT1292655	hsa-miR-1825	CLIP-seq
MIRT1292656	hsa-miR-1909	CLIP-seq
MIRT1292657	hsa-miR-2355-5p	CLIP-seq
MIRT1292658	hsa-miR-3120-5p	CLIP-seq
MIRT1292659	hsa-miR-3150b-3p	CLIP-seq
MIRT1292660	hsa-miR-3182	CLIP-seq
MIRT1292661	hsa-miR-328	CLIP-seq
MIRT1292662	hsa-miR-339-5p	CLIP-seq
MIRT1292663	hsa-miR-342-3p	CLIP-seq
MIRT1292664	hsa-miR-346	CLIP-seq
MIRT1292665	hsa-miR-3612	CLIP-seq
MIRT1292666	hsa-miR-3679-3p	CLIP-seq
MIRT1292667	hsa-miR-371b-3p	CLIP-seq
MIRT1292668	hsa-miR-3915	CLIP-seq
MIRT1292669	hsa-miR-4251	CLIP-seq
MIRT1292670	hsa-miR-4286	CLIP-seq
MIRT1292671	hsa-miR-4288	CLIP-seq
MIRT1292672	hsa-miR-4303	CLIP-seq
MIRT1292673	hsa-miR-4329	CLIP-seq
MIRT1292674	hsa-miR-4459	CLIP-seq
MIRT1292675	hsa-miR-4640-5p	CLIP-seq
MIRT1292676	hsa-miR-4649-3p	CLIP-seq
MIRT1292677	hsa-miR-4652-3p	CLIP-seq
MIRT1292678	hsa-miR-4689	CLIP-seq
MIRT1292679	hsa-miR-4695-5p	CLIP-seq
MIRT1292680	hsa-miR-4717-5p	CLIP-seq
MIRT1292681	hsa-miR-4725-5p	CLIP-seq
MIRT1292682	hsa-miR-4726-5p	CLIP-seq
MIRT1292683	hsa-miR-4784	CLIP-seq
MIRT1292684	hsa-miR-490-3p	CLIP-seq
MIRT1292685	hsa-miR-504	CLIP-seq
MIRT1292686	hsa-miR-5096	CLIP-seq
MIRT1292687	hsa-miR-515-5p	CLIP-seq
MIRT1292688	hsa-miR-632	CLIP-seq
MIRT1292689	hsa-miR-650	CLIP-seq
MIRT1292674	hsa-miR-4459	CLIP-seq
MIRT2086928	hsa-miR-4512	CLIP-seq
MIRT2086929	hsa-miR-4779	CLIP-seq
MIRT1292663	hsa-miR-342-3p	CLIP-seq
MIRT2457790	hsa-miR-185	CLIP-seq
MIRT2457791	hsa-miR-3119	CLIP-seq
MIRT2457792	hsa-miR-3126-5p	CLIP-seq
MIRT2457793	hsa-miR-3622a-3p	CLIP-seq
MIRT2457794	hsa-miR-3622b-3p	CLIP-seq
MIRT2457795	hsa-miR-4306	CLIP-seq
MIRT2457796	hsa-miR-4419a	CLIP-seq
MIRT2457797	hsa-miR-4510	CLIP-seq
MIRT2457798	hsa-miR-4644	CLIP-seq
MIRT1292681	hsa-miR-4725-5p	CLIP-seq
MIRT1292685	hsa-miR-504	CLIP-seq
MIRT2457799	hsa-miR-544b	CLIP-seq
MIRT1292648	hsa-miR-10a	CLIP-seq
MIRT1292649	hsa-miR-10b	CLIP-seq
MIRT1292650	hsa-miR-1182	CLIP-seq
MIRT2608228	hsa-miR-1205	CLIP-seq
MIRT1292651	hsa-miR-1207-3p	CLIP-seq
MIRT1292652	hsa-miR-1224-5p	CLIP-seq
MIRT2608229	hsa-miR-1238	CLIP-seq
MIRT2608230	hsa-miR-124	CLIP-seq
MIRT2608231	hsa-miR-1254	CLIP-seq
MIRT2608232	hsa-miR-125a-5p	CLIP-seq
MIRT2608233	hsa-miR-125b	CLIP-seq
MIRT2608234	hsa-miR-1266	CLIP-seq
MIRT2608235	hsa-miR-181a	CLIP-seq
MIRT2608236	hsa-miR-181b	CLIP-seq
MIRT2608237	hsa-miR-181c	CLIP-seq
MIRT2608238	hsa-miR-181d	CLIP-seq
MIRT2457790	hsa-miR-185	CLIP-seq
MIRT1292656	hsa-miR-1909	CLIP-seq
MIRT2608239	hsa-miR-1915	CLIP-seq
MIRT2608240	hsa-miR-1976	CLIP-seq
MIRT1292657	hsa-miR-2355-5p	CLIP-seq
MIRT2608241	hsa-miR-2467-3p	CLIP-seq
MIRT2608242	hsa-miR-3116	CLIP-seq
MIRT1292658	hsa-miR-3120-5p	CLIP-seq
MIRT2608243	hsa-miR-3124-3p	CLIP-seq
MIRT2457792	hsa-miR-3126-5p	CLIP-seq
MIRT2608244	hsa-miR-3127-5p	CLIP-seq
MIRT2608245	hsa-miR-3130-3p	CLIP-seq
MIRT2608246	hsa-miR-3136-3p	CLIP-seq
MIRT1292659	hsa-miR-3150b-3p	CLIP-seq
MIRT1292660	hsa-miR-3182	CLIP-seq
MIRT2608247	hsa-miR-323-3p	CLIP-seq
MIRT2608248	hsa-miR-342-5p	CLIP-seq
MIRT1292664	hsa-miR-346	CLIP-seq
MIRT1292665	hsa-miR-3612	CLIP-seq
MIRT2608249	hsa-miR-3614-5p	CLIP-seq
MIRT2608250	hsa-miR-3616-3p	CLIP-seq
MIRT2457793	hsa-miR-3622a-3p	CLIP-seq
MIRT2457794	hsa-miR-3622b-3p	CLIP-seq
MIRT2608251	hsa-miR-3664-3p	CLIP-seq
MIRT2608252	hsa-miR-3678-3p	CLIP-seq
MIRT1292666	hsa-miR-3679-3p	CLIP-seq
MIRT2608253	hsa-miR-370	CLIP-seq
MIRT2608254	hsa-miR-3714	CLIP-seq
MIRT2608255	hsa-miR-376a	CLIP-seq
MIRT2608256	hsa-miR-376b	CLIP-seq
MIRT2608257	hsa-miR-3910	CLIP-seq
MIRT1292668	hsa-miR-3915	CLIP-seq
MIRT2608258	hsa-miR-3918	CLIP-seq
MIRT2608259	hsa-miR-4254	CLIP-seq
MIRT2608260	hsa-miR-4262	CLIP-seq
MIRT1292670	hsa-miR-4286	CLIP-seq
MIRT1292671	hsa-miR-4288	CLIP-seq
MIRT2608261	hsa-miR-4297	CLIP-seq
MIRT2608262	hsa-miR-4301	CLIP-seq
MIRT2457795	hsa-miR-4306	CLIP-seq
MIRT2608263	hsa-miR-4318	CLIP-seq
MIRT2608264	hsa-miR-4319	CLIP-seq
MIRT2457796	hsa-miR-4419a	CLIP-seq
MIRT2608265	hsa-miR-4436b-3p	CLIP-seq
MIRT1292674	hsa-miR-4459	CLIP-seq
MIRT2457797	hsa-miR-4510	CLIP-seq
MIRT2608266	hsa-miR-4518	CLIP-seq
MIRT2457798	hsa-miR-4644	CLIP-seq
MIRT1292676	hsa-miR-4649-3p	CLIP-seq
MIRT2608267	hsa-miR-4650-5p	CLIP-seq
MIRT1292677	hsa-miR-4652-3p	CLIP-seq
MIRT2608268	hsa-miR-4664-5p	CLIP-seq
MIRT2608269	hsa-miR-4677-3p	CLIP-seq
MIRT1292678	hsa-miR-4689	CLIP-seq
MIRT2608270	hsa-miR-4693-5p	CLIP-seq
MIRT1292679	hsa-miR-4695-5p	CLIP-seq
MIRT1292680	hsa-miR-4717-5p	CLIP-seq
MIRT2608271	hsa-miR-4718	CLIP-seq
MIRT2608272	hsa-miR-4721	CLIP-seq
MIRT1292681	hsa-miR-4725-5p	CLIP-seq
MIRT2608273	hsa-miR-4732-3p	CLIP-seq
MIRT2608274	hsa-miR-4753-5p	CLIP-seq
MIRT2608275	hsa-miR-4763-5p	CLIP-seq
MIRT1292683	hsa-miR-4784	CLIP-seq
MIRT2608276	hsa-miR-4786-5p	CLIP-seq
MIRT2608277	hsa-miR-4793-3p	CLIP-seq
MIRT2608278	hsa-miR-483-3p	CLIP-seq
MIRT1292685	hsa-miR-504	CLIP-seq
MIRT2608279	hsa-miR-506	CLIP-seq
MIRT1292687	hsa-miR-515-5p	CLIP-seq
MIRT2608280	hsa-miR-521	CLIP-seq
MIRT2457799	hsa-miR-544b	CLIP-seq
MIRT2608281	hsa-miR-626	CLIP-seq
MIRT1292688	hsa-miR-632	CLIP-seq
MIRT2608282	hsa-miR-637	CLIP-seq
MIRT2608283	hsa-miR-646	CLIP-seq
MIRT1292689	hsa-miR-650	CLIP-seq
MIRT2608284	hsa-miR-670	CLIP-seq
MIRT2608285	hsa-miR-767-5p	CLIP-seq
MIRT2608286	hsa-miR-769-5p	CLIP-seq
MIRT2608287	hsa-miR-892a	CLIP-seq
MIRT1292648	hsa-miR-10a	CLIP-seq
MIRT1292649	hsa-miR-10b	CLIP-seq
MIRT2608228	hsa-miR-1205	CLIP-seq
MIRT1292651	hsa-miR-1207-3p	CLIP-seq
MIRT1292652	hsa-miR-1224-5p	CLIP-seq
MIRT2608229	hsa-miR-1238	CLIP-seq
MIRT2608230	hsa-miR-124	CLIP-seq
MIRT2608231	hsa-miR-1254	CLIP-seq
MIRT2608234	hsa-miR-1266	CLIP-seq
MIRT2608235	hsa-miR-181a	CLIP-seq
MIRT2608236	hsa-miR-181b	CLIP-seq
MIRT2608237	hsa-miR-181c	CLIP-seq
MIRT2608238	hsa-miR-181d	CLIP-seq
MIRT2608239	hsa-miR-1915	CLIP-seq
MIRT2608240	hsa-miR-1976	CLIP-seq
MIRT1292657	hsa-miR-2355-5p	CLIP-seq
MIRT2608241	hsa-miR-2467-3p	CLIP-seq
MIRT2608242	hsa-miR-3116	CLIP-seq
MIRT1292658	hsa-miR-3120-5p	CLIP-seq
MIRT2608243	hsa-miR-3124-3p	CLIP-seq
MIRT2608244	hsa-miR-3127-5p	CLIP-seq
MIRT2608245	hsa-miR-3130-3p	CLIP-seq
MIRT2608246	hsa-miR-3136-3p	CLIP-seq
MIRT1292659	hsa-miR-3150b-3p	CLIP-seq
MIRT1292660	hsa-miR-3182	CLIP-seq
MIRT2608247	hsa-miR-323-3p	CLIP-seq
MIRT2608248	hsa-miR-342-5p	CLIP-seq
MIRT1292664	hsa-miR-346	CLIP-seq
MIRT1292665	hsa-miR-3612	CLIP-seq
MIRT2608249	hsa-miR-3614-5p	CLIP-seq
MIRT2608250	hsa-miR-3616-3p	CLIP-seq
MIRT2608251	hsa-miR-3664-3p	CLIP-seq
MIRT2608252	hsa-miR-3678-3p	CLIP-seq
MIRT1292666	hsa-miR-3679-3p	CLIP-seq
MIRT2608253	hsa-miR-370	CLIP-seq
MIRT2608254	hsa-miR-3714	CLIP-seq
MIRT2608255	hsa-miR-376a	CLIP-seq
MIRT2608256	hsa-miR-376b	CLIP-seq
MIRT2608257	hsa-miR-3910	CLIP-seq
MIRT1292668	hsa-miR-3915	CLIP-seq
MIRT2608258	hsa-miR-3918	CLIP-seq
MIRT2608259	hsa-miR-4254	CLIP-seq
MIRT2608260	hsa-miR-4262	CLIP-seq
MIRT1292670	hsa-miR-4286	CLIP-seq
MIRT1292671	hsa-miR-4288	CLIP-seq
MIRT2608261	hsa-miR-4297	CLIP-seq
MIRT2608262	hsa-miR-4301	CLIP-seq
MIRT2608263	hsa-miR-4318	CLIP-seq
MIRT2608265	hsa-miR-4436b-3p	CLIP-seq
MIRT1292674	hsa-miR-4459	CLIP-seq
MIRT2608266	hsa-miR-4518	CLIP-seq
MIRT1292676	hsa-miR-4649-3p	CLIP-seq
MIRT2608267	hsa-miR-4650-5p	CLIP-seq
MIRT1292677	hsa-miR-4652-3p	CLIP-seq
MIRT2608268	hsa-miR-4664-5p	CLIP-seq
MIRT2608269	hsa-miR-4677-3p	CLIP-seq
MIRT1292678	hsa-miR-4689	CLIP-seq
MIRT2608270	hsa-miR-4693-5p	CLIP-seq
MIRT1292679	hsa-miR-4695-5p	CLIP-seq
MIRT1292680	hsa-miR-4717-5p	CLIP-seq
MIRT2608271	hsa-miR-4718	CLIP-seq
MIRT2608272	hsa-miR-4721	CLIP-seq
MIRT1292681	hsa-miR-4725-5p	CLIP-seq
MIRT2608274	hsa-miR-4753-5p	CLIP-seq
MIRT2608275	hsa-miR-4763-5p	CLIP-seq
MIRT1292683	hsa-miR-4784	CLIP-seq
MIRT2608276	hsa-miR-4786-5p	CLIP-seq
MIRT2608277	hsa-miR-4793-3p	CLIP-seq
MIRT2608278	hsa-miR-483-3p	CLIP-seq
MIRT1292685	hsa-miR-504	CLIP-seq
MIRT2608279	hsa-miR-506	CLIP-seq
MIRT2608280	hsa-miR-521	CLIP-seq
MIRT2608281	hsa-miR-626	CLIP-seq
MIRT1292688	hsa-miR-632	CLIP-seq
MIRT2608282	hsa-miR-637	CLIP-seq
MIRT2608283	hsa-miR-646	CLIP-seq
MIRT1292689	hsa-miR-650	CLIP-seq
MIRT2608285	hsa-miR-767-5p	CLIP-seq
MIRT2608286	hsa-miR-769-5p	CLIP-seq
MIRT2608287	hsa-miR-892a	CLIP-seq

Transcription factors

Show/Hide all(4)

Transcription factor	Regulation	Reference
DNMT1	Unknown	24247422
SP1	Activation	19450668
SP3	Activation	19450668
TP53	Repression	21364923

Show/Hide all(25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000922	Component	Spindle pole	IEA
GO:0005515	Function	Protein binding	IPI	11857081, 12762840, 14729613, 14743218, 15109305, 16810318, 18347058, 18566590, 20562859, 20920251, 21134643, 21199877, 23455924, 28514442, 32296183, 32814053, 35512704
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	14743218, 18566590
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IEA
GO:0005819	Component	Spindle	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0006974	Process	DNA damage response	IMP	18566590
GO:0007165	Process	Signal transduction	IEA
GO:0007265	Process	Ras protein signal transduction	IBA
GO:0007265	Process	Ras protein signal transduction	IDA	15109305
GO:0008270	Function	Zinc ion binding	IEA
GO:0008270	Function	Zinc ion binding	TAS	11333291
GO:0015630	Component	Microtubule cytoskeleton	IBA
GO:0015630	Component	Microtubule cytoskeleton	IDA	14743218, 18566590
GO:0031267	Function	Small GTPase binding	IEA
GO:0031398	Process	Positive regulation of protein ubiquitination	IDA	18566590
GO:0042802	Function	Identical protein binding	IPI	11857081, 20920251
GO:0046872	Function	Metal ion binding	IEA
GO:0050821	Process	Protein stabilization	IDA	18566590
GO:0051726	Process	Regulation of cell cycle	IDA	18566590
GO:1902806	Process	Regulation of cell cycle G1/S phase transition	IMP	12024041

MIM	HGNC	e!Ensembl
605082	9882	ENSG00000068028

Protein

UniProt ID

Q9NS23

Protein name

Ras association domain-containing protein 1

Protein function

Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformation

PDB

2KZU

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00788	RA	202 → 292	Ras association (RalGDS/AF-6) domain	Domain
PF16517	Nore1-SARAH	299 → 338	Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Isoform A and isoform C are ubiquitously expressed in all tissues tested, however isoform A is absent in many corresponding cancer cell lines. Isoform B is mainly expressed in hematopoietic cells. {ECO:0000269|PubMed:10888881, ECO:0000

Sequence

MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
THTWCDLCGDFIWGVVRKGLQCARLSADCKFTCHYRCRALVCLDCCGPRDLGWEPAVERD
TNVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSV
PSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVV
DDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAF
SMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG

Sequence length

344

Interactions

View interactions

	KEGG
	Ras signaling pathway Hippo signaling pathway Hippo signaling pathway - multiple species Pathways in cancer MicroRNAs in cancer Bladder cancer Non-small cell lung cancer

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Neuroticism	Neuroticism	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (170)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma	Associate	14511407, 17967182, 18494062, 19926549, 20193080, 21102258, 21507233
Adenocarcinoma	Inhibit	18182852
Adenocarcinoma in Situ	Associate	21731750
Adenocarcinoma of Lung	Associate	21731750, 23902976
Adenoma	Associate	17923875, 18182852, 23764768, 28600574
Adenoma	Inhibit	23865079
Adenoma Liver Cell	Associate	16606445
Adenoma Oxyphilic	Associate	31773698
Adenoma Pleomorphic	Associate	21063414, 23510689
Adenomatous Polyposis Coli	Inhibit	39607643
Adenomatous Polyps	Associate	22020530
Adrenocortical Carcinoma	Inhibit	23915220
Aplasia of Lacrimal and Salivary Glands	Associate	26125908
Astrocytoma	Associate	15367334, 18298842, 21339190
Ataxia Telangiectasia	Associate	26648328
Biliary Tract Neoplasms	Associate	15471559, 18182852
Brain Neoplasms	Associate	16641902, 23661397, 24968695, 25482183, 26457492, 32783304
Breast Diseases	Associate	20627767
Breast Neoplasms	Inhibit	11333291, 14735202, 34831091
Breast Neoplasms	Associate	11839581, 12819009, 16641902, 17611401, 17764565, 17998253, 17998817, 18172292, 18381931, 18485221, 19153192, 19367284, 19657672, 19755643, 19829046 View all (43 more)
Calcinosis Cutis	Associate	23154831, 36652664
Carcinogenesis	Inhibit	16344548
Carcinogenesis	Associate	16606445, 17170014, 17634119, 18182852, 18469797, 18783461, 21878113, 23510689, 25040980, 26549256, 27516190
Carcinoid Tumor	Inhibit	21036752
Carcinoma Adenoid Cystic	Associate	15959912
Carcinoma Basal Cell	Inhibit	20505321
Carcinoma Basal Cell	Associate	23284750
Carcinoma Ductal	Associate	22925694
Carcinoma Endometrioid	Associate	17170014, 18783461
Carcinoma Hepatocellular	Associate	12433278, 14507645, 16606445, 18161048, 20079733, 20364114, 21338215, 23594797, 25923138, 26000761, 26019036, 26881524, 27078152, 28951629, 30689554, 38062093 View all (1 more)
Carcinoma Hepatocellular	Inhibit	40419121
Carcinoma Intraductal Noninfiltrating	Associate	18769130, 20056007, 24093668, 25331261, 28893223
Carcinoma Large Cell	Associate	14511407
Carcinoma Non Small Cell Lung	Inhibit	14500366, 20193080
Carcinoma Non Small Cell Lung	Associate	14511407, 15042681, 16444703, 16644104, 18337602, 18349282, 19156899, 19926549, 20521346, 20736951, 24937636, 24998565, 25040980, 26112163, 31791387, 31839603, 32605217, 33442234 View all (3 more)
Carcinoma Ovarian Epithelial	Associate	24460357, 25966226
Carcinoma Renal Cell	Associate	11390984, 14735202, 16707423, 18822131, 20038516, 21713763, 26648328, 28160561, 31773698
Carcinoma Renal Cell	Inhibit	17634119
Carcinoma Squamous Cell	Associate	14511407, 20193080, 21507233, 23478628, 23637996
Carcinoma Squamous Cell	Inhibit	26112163, 35491677
Carcinoma Transitional Cell	Associate	18192966
Cholangiocarcinoma	Associate	15467712, 15761971, 29484968
Chordoma	Associate	23533570
Colitis Ulcerative	Inhibit	30604274
Colorectal Neoplasms	Associate	15122305, 15526363, 16369045, 16513682, 18494062, 18592002, 19404924, 20970032, 21274674, 22020530, 22880157, 23128528, 23573237, 23975090, 24500500 View all (7 more)
Colorectal Neoplasms	Inhibit	23865079
Death	Associate	31055025
Drug Related Side Effects and Adverse Reactions	Associate	25526566, 26894600
Dystonic Disorders	Associate	27292796
Ectodermal Dysplasia	Associate	15959912
Ectrodactyly Ectodermal Dysplasia And Cleft Lip Palate Syndrome 1	Associate	18783461
Endocrine Gland Neoplasms	Associate	26125908
Endometrial Hyperplasia	Associate	17170014
Endometrial Neoplasms	Associate	17170014, 18469797, 31623109, 31787246, 31902687
Ependymoma	Associate	34854470
Esophageal Neoplasms	Associate	25886188, 27506957
Esophageal Squamous Cell Carcinoma	Associate	21150312, 25514805, 25886188
Fibrolamellar hepatocellular carcinoma	Associate	18264082, 21060828
Fibrosis	Associate	16606445, 25152984
Focal Epithelial Hyperplasia	Associate	11839581
Gallbladder Neoplasms	Associate	18182852
Gastritis	Associate	14507661
Gastrointestinal Neoplasms	Associate	32883271
Glioblastoma	Associate	19809523
Glioma	Associate	18616639, 21339190, 25563195, 31055025, 32783304
Glucosephosphate Dehydrogenase Deficiency	Associate	25677060
Head and Neck Neoplasms	Associate	21063414
Hepatitis B	Associate	20364114
Hepatitis Chronic	Associate	23594797
Hereditary Breast and Ovarian Cancer Syndrome	Associate	11390984, 18172292, 30049201
Histiocytoma Benign Fibrous	Associate	21649526
Hyperplasia	Associate	27511358
Idiopathic Noncirrhotic Portal Hypertension	Associate	27078152
Inflammation	Associate	19809523, 36983040
Inflammatory Bowel Diseases	Associate	30604274, 36983040
Kidney Diseases	Associate	11390984, 28160561
Kidney Neoplasms	Associate	17645803, 27725787, 31773698
Klatskin Tumor	Associate	21450690
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	35421941
Leukemia Myeloid Acute	Associate	26894600
Leukemia Myelomonocytic Juvenile	Associate	15801956
Liver Cirrhosis	Associate	16606445, 30689554
Liver Diseases	Associate	27078152
Liver Failure	Associate	16606445
Lung Neoplasms	Associate	16444703, 16644104, 17477876, 17876837, 19156899, 22146010, 22169480, 22591718, 23614702, 23771539, 25040980, 25719833, 26112163, 27716889, 29851970 View all (8 more)
Lung Neoplasms	Inhibit	20193080, 20440268, 28634396
Lymphatic Metastasis	Associate	16258509, 19926549, 23573237, 31638213
Lymphatic Metastasis	Inhibit	23478628
Lymphoma Follicular	Associate	26457492
Lymphoma Non Hodgkin	Associate	26392358
Malformations of Cortical Development Group I	Associate	16510600
Medulloblastoma	Associate	21880625
Melanoma	Associate	15596045, 16374457, 16510600, 19223509, 21081840, 21788308, 23209607
Melanoma	Inhibit	35941108
Melanoma Cutaneous Malignant	Associate	15064737, 18211945, 23125005
Meningioma	Associate	25648363
Mesothelioma Malignant	Associate	22146010
Mixed Tumor Malignant	Associate	15980887
Monoclonal Gammopathy of Undetermined Significance	Associate	15197802
Mouth Neoplasms	Associate	31013839
Multiple Myeloma	Associate	14616967, 15197802
Multiple Pulmonary Nodules	Associate	31436249, 33691657
Muscular Disorders Atrophic	Associate	17170014
Myelodysplastic Syndromes	Associate	15801956
Nasopharyngeal Carcinoma	Associate	16096369, 16229803, 17201146, 19129950, 20042089, 21535891, 24197116, 25824751, 38115290
Nasopharyngeal Neoplasms	Associate	38115290
Necrosis	Associate	25331261
Neoplasm Invasiveness	Associate	26549256
Neoplasm Metastasis	Associate	15959912, 16258509, 18494062, 21731750, 23573237, 24478455, 27880743
Neoplasm Metastasis	Inhibit	26648328, 27765918
Neoplasms	Inhibit	11333291, 14500366, 15467712, 15471559, 15761971, 15870267, 15949439, 15963934, 16096369, 16229803, 16344548, 16434257, 16444703, 16510573, 16510600 View all (102 more)
Neoplasms	Associate	11390984, 12433278, 12762840, 12819009, 14501508, 14735202, 15064737, 15292941, 15389252, 15546880, 15959912, 16224153, 16258509, 16502411, 16606445 View all (93 more)
Neoplasms	Stimulate	31773698
Neoplasms Germ Cell and Embryonal	Associate	15149548
Neoplasms Germ Cell and Embryonal	Stimulate	33224314
Neoplasms Glandular and Epithelial	Associate	17645803
Neuroblastoma	Inhibit	14500366
Neuroblastoma	Associate	17064406, 18298842, 19165202, 22695170, 23144874, 34820594
Neuroendocrine Tumors	Associate	16258509, 21036752, 29851970
Neurofibrosarcoma	Associate	25038505
Niemann Pick Disease Type C	Associate	20042089
Noma	Associate	26125908
Non functioning pancreatic endocrine tumor	Associate	21838870
Non Muscle Invasive Bladder Neoplasms	Associate	24252461
Nonseminomatous germ cell tumor	Associate	12495446
Oropharyngeal Neoplasms	Associate	31013839
Osteosarcoma	Associate	27880743
Ovarian Neoplasms	Associate	18757082, 19962312, 21056906, 22871047, 28206954, 29670073, 31653147
Pancreatic Intraductal Neoplasms	Associate	35013462
Pancreatic Neoplasms	Associate	14501508, 26782786, 34629822
Papilloma Intraductal	Associate	11839581
Parathyroid Neoplasms	Associate	20208994, 23764768, 28600574
Parathyroid Neoplasms	Inhibit	39607643
Pelvic Neoplasms	Associate	29587736
Pleural Effusion	Associate	37158875, 37811622
Pleural Effusion Malignant	Associate	37158875, 37811622, 40164346
Pre Eclampsia	Associate	26694356
Prostatic Hyperplasia	Associate	27511358
Prostatic Neoplasms	Associate	17465221, 18076941, 18637271, 21694441, 21822036, 22672250, 24001151, 24938434, 27511358, 27576364, 29660369, 31115550, 34183450, 34581895, 38493315
Prostatitis	Associate	15292941, 19454503, 24001151, 27511358
Radial Neuropathy	Inhibit	30305100
Respiratory Tract Infections	Associate	25613404
Retinal Dysplasia	Associate	30604274
Retinoblastoma	Associate	15799820
Rhabdomyosarcoma	Associate	36652664
Salivary Gland Adenoma Pleomorphic	Associate	21063414
Sarcoma	Associate	16258501, 22389451
Sarcoma Ewing	Associate	18347058, 23887284
Sex Chromosome Disorders	Associate	20847278
Sinonasal undifferentiated carcinoma	Associate	27516190
Small Cell Lung Carcinoma	Associate	11333291, 16444703, 31791387
Solitary Pulmonary Nodule	Associate	31436249
Squamous Cell Carcinoma of Head and Neck	Associate	22246327, 27027429, 29790687, 33786612, 37470582
Squamous Intraepithelial Lesions	Inhibit	35491677
Stomach Diseases	Stimulate	18494062
Stomach Neoplasms	Associate	12695555, 12746473, 18203293, 18494062, 24748501, 30106448, 33928818
Stomach Neoplasms	Inhibit	17608924, 26735582
Testicular Germ Cell Tumor	Associate	37508506
Thyroid cancer follicular	Associate	38203733
Thyroid Diseases	Associate	38203733
Thyroid Neoplasms	Associate	15980887, 22694820, 26457492, 38203733
Thyroid Nodule	Associate	26457492
Thyroiditis	Associate	15980887
Triple Negative Breast Neoplasms	Associate	17764565, 25068292, 30003738
Urethral Neoplasms	Associate	16775427
Urinary Bladder Diseases	Associate	18702824, 23527093
Urinary Bladder Neoplasms	Associate	17404085, 18702824, 21599969, 27814275, 31500788, 34806159
Uterine Cervical Neoplasms	Associate	23478628, 25081722
Uveal melanoma	Inhibit	21788308
Wilms Tumor	Associate	34820594, 35436013

RASSF1 (Ras association domain family member 1)