Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	11141
Gene name	Interleukin 1 receptor accessory protein like 1
Gene symbol	IL1RAPL1
Synonyms (NCBI Gene)	IL-1-RAPL-1IL-1RAPL-1IL1R8IL1RAPLIL1RAPL-1MRX10MRX21MRX34OPHN4TIGIRR-2
Chromosome	X
Chromosome location	Xp21.3-p21.2
Summary	The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane do

Show/Hide all (6)

SNP ID	Visualize variation	Clinical significance	Consequence
rs122461160	C>A	Pathogenic	Coding sequence variant, stop gained
rs122461161	G>A	Pathogenic	Coding sequence variant, stop gained
rs878853146	TTGGGAAAGT>-	Pathogenic	Frameshift variant, coding sequence variant
rs886041775	G>A	Pathogenic	Splice donor variant
rs1064795372	AGA>-	Likely-pathogenic, not-provided	Coding sequence variant, inframe deletion
rs1569203705	C>T	Pathogenic	Coding sequence variant, stop gained

378

Show/Hide all (378)

miRTarBase ID	miRNA	Experiments	Reference
MIRT053613	hsa-miR-151a-5p	Luciferase reporter assayqRT-PCRWestern blot	22928040
MIRT721948	hsa-miR-100-3p	HITS-CLIP	19536157
MIRT721947	hsa-miR-4279	HITS-CLIP	19536157
MIRT721946	hsa-miR-3161	HITS-CLIP	19536157
MIRT721945	hsa-miR-599	HITS-CLIP	19536157
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	19536157
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	19536157
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	22927820
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	22927820
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	22927820
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT674564	hsa-miR-5197-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	24906430
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	24906430
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	24906430
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	24906430
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	24906430
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	24906430
MIRT523020	hsa-miR-8485	PAR-CLIP	23446348
MIRT523019	hsa-miR-6768-5p	PAR-CLIP	23446348
MIRT523018	hsa-miR-4307	PAR-CLIP	23446348
MIRT628095	hsa-miR-147a	HITS-CLIP	27418678
MIRT628095	hsa-miR-147a	HITS-CLIP	27418678
MIRT575315	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT575315	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT575314	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT575314	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	27418678
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	27418678
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	27418678
MIRT628101	hsa-miR-3911	HITS-CLIP	27418678
MIRT628101	hsa-miR-3911	HITS-CLIP	27418678
MIRT575311	hsa-miR-3941	HITS-CLIP	27418678
MIRT575311	hsa-miR-3941	HITS-CLIP	27418678
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	27418678
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	27418678
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	27418678
MIRT628094	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT628094	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT575313	hsa-miR-603	HITS-CLIP	27418678
MIRT575313	hsa-miR-603	HITS-CLIP	27418678
MIRT628100	hsa-miR-644a	HITS-CLIP	27418678
MIRT628100	hsa-miR-644a	HITS-CLIP	27418678
MIRT628102	hsa-miR-663b	HITS-CLIP	27418678
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	27418678
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	27418678
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	27418678
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	27418678
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	27418678
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	27418678
MIRT523020	hsa-miR-8485	HITS-CLIP	27418678
MIRT523020	hsa-miR-8485	HITS-CLIP	27418678
MIRT721948	hsa-miR-100-3p	HITS-CLIP	19536157
MIRT721947	hsa-miR-4279	HITS-CLIP	19536157
MIRT721946	hsa-miR-3161	HITS-CLIP	19536157
MIRT721945	hsa-miR-599	HITS-CLIP	19536157
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	19536157
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	19536157
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	22927820
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	22927820
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	22927820
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT674564	hsa-miR-5197-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	PAR-CLIP	23446348
MIRT523019	hsa-miR-6768-5p	PAR-CLIP	23446348
MIRT523018	hsa-miR-4307	PAR-CLIP	23446348
MIRT1064396	hsa-miR-1269	CLIP-seq
MIRT1064397	hsa-miR-1269b	CLIP-seq
MIRT1064398	hsa-miR-1288	CLIP-seq
MIRT1064399	hsa-miR-3158-5p	CLIP-seq
MIRT1064400	hsa-miR-3654	CLIP-seq
MIRT1064401	hsa-miR-378	CLIP-seq
MIRT1064402	hsa-miR-378b	CLIP-seq
MIRT1064403	hsa-miR-378c	CLIP-seq
MIRT1064404	hsa-miR-378d	CLIP-seq
MIRT1064405	hsa-miR-378e	CLIP-seq
MIRT1064406	hsa-miR-378f	CLIP-seq
MIRT1064407	hsa-miR-378h	CLIP-seq
MIRT1064408	hsa-miR-378i	CLIP-seq
MIRT1064409	hsa-miR-422a	CLIP-seq
MIRT1064410	hsa-miR-4269	CLIP-seq
MIRT1064411	hsa-miR-4418	CLIP-seq
MIRT1064412	hsa-miR-4515	CLIP-seq
MIRT1064413	hsa-miR-4645-5p	CLIP-seq
MIRT1064414	hsa-miR-4673	CLIP-seq
MIRT1064415	hsa-miR-4740-5p	CLIP-seq
MIRT1064416	hsa-miR-509-3-5p	CLIP-seq
MIRT1064417	hsa-miR-509-5p	CLIP-seq
MIRT2015297	hsa-miR-1915	CLIP-seq
MIRT2015298	hsa-miR-2964a-5p	CLIP-seq
MIRT2015299	hsa-miR-4714-3p	CLIP-seq
MIRT2015300	hsa-miR-4726-3p	CLIP-seq

Show/Hide all (38)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005102	Function	Signaling receptor binding	ISS
GO:0005515	Function	Protein binding	IPI	12783849, 21940441
GO:0005737	Component	Cytoplasm	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	12783849
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0007165	Process	Signal transduction	IEA
GO:0007166	Process	Cell surface receptor signaling pathway	IBA
GO:0009986	Component	Cell surface	IBA
GO:0009986	Component	Cell surface	ISS
GO:0010975	Process	Regulation of neuron projection development	ISS
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0019966	Function	Interleukin-1 binding	IDA	12783849
GO:0030182	Process	Neuron differentiation	ISS
GO:0030424	Component	Axon	IEA
GO:0030425	Component	Dendrite	IEA
GO:0030425	Component	Dendrite	ISS
GO:0042995	Component	Cell projection	IEA
GO:0045211	Component	Postsynaptic membrane	NAS	21940441
GO:0045920	Process	Negative regulation of exocytosis	IBA
GO:0045920	Process	Negative regulation of exocytosis	IDA	12783849
GO:0051965	Process	Positive regulation of synapse assembly	ISS
GO:0061003	Process	Positive regulation of dendritic spine morphogenesis	ISS
GO:0061809	Function	NAD+ nucleosidase activity, cyclic ADP-ribose generating	IEA
GO:0097105	Process	Presynaptic membrane assembly	ISS
GO:0098978	Component	Glutamatergic synapse	IDA	21926414
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0098978	Component	Glutamatergic synapse	IMP	21926414
GO:0099175	Process	Regulation of postsynapse organization	IDA	21926414
GO:0099175	Process	Regulation of postsynapse organization	IMP	21926414
GO:0099545	Process	Trans-synaptic signaling by trans-synaptic complex	IDA	21926414
GO:0099545	Process	Trans-synaptic signaling by trans-synaptic complex	IMP	21926414
GO:0099560	Process	Synaptic membrane adhesion	ISS
GO:1905606	Process	Regulation of presynapse assembly	IDA	21926414
GO:1905606	Process	Regulation of presynapse assembly	IEA
GO:1905606	Process	Regulation of presynapse assembly	IMP	21926414

MIM	HGNC	e!Ensembl
300206	5996	ENSG00000169306

Q9NZN1

Protein name

Interleukin-1 receptor accessory protein-like 1 (IL-1-RAPL-1) (IL-1RAPL-1) (IL1RAPL-1) (EC 3.2.2.6) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2) (X-linked interleukin-1 receptor accessory protein-like 1)

Protein function

May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel (PubMed:12783849). May activate the MAP kinase JNK (PubMed:15123616). Plays a role in neurite outgrowth (By similar

PDB

1T3G , 4M92 , 5WY8

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF18452	Ig_6	92 → 143	Immunoglobulin domain	Domain
PF00047	ig	251 → 348	Immunoglobulin domain	Domain
PF01582	TIR	404 → 579	TIR domain	Family

Tissue specificity

TISSUE SPECIFICITY: Detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. Detected at very low levels in tonsil, prostate, testis, small intestine, placenta,

Sequence

MKAPIPHLILLYATFTQSLKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYI
RTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVI
RNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEIL
WYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDK
PPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWE
SDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVEL
AGGLGAILLLLVCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWN
QETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPN
YVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTVIKWH
GPKCNKLNSKFWKRLQYEMPFKRIEPITHEQALDVSEQGPFGELQTVSAISMAAATSTAL
ATAHPDLRSTFHNTYHSQMRQKHYYRSYEYDVPPTGTLPLTSIGNQHTYCNIPMTLINGQ
RPQTKSSREQNPDEAHTNSAILPLLPRETSISSVIW

Sequence length

696

Interactions

View interactions

	Reactome
			Receptor-type tyrosine-protein phosphatases Interleukin-38 signaling

Show/Hide Causal Diseases (4)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
IL1RAPL1-related disorder	Likely pathogenic	rs1064795372	RCV000509346
Intellectual disability	Pathogenic; Likely pathogenic	rs878853146, rs1933958646	RCV000224084 RCV001260739
Intellectual disability, X-linked 21	Likely pathogenic; Pathogenic	rs2147259265, rs2147251555, rs2147258610, rs781674023, rs122461160, rs122461161, rs2519091663, rs2518875196, rs2518941201, rs1569208908, rs1569203705	RCV001527626 RCV001775394 RCV001779415 RCV001814756 RCV000012235 RCV000012236 RCV003314205 RCV004586383 RCV004593553 RCV000760253 RCV004027174
See cases	Likely pathogenic	rs2147239911	RCV001420276

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Developmental disorder	Uncertain significance	rs2147258668	RCV001843727
Familial cancer of breast	Benign	rs6526806	RCV005895486
Hepatocellular carcinoma	Benign; Likely benign	rs138267399	RCV005908870
History of neurodevelopmental disorder	Benign; Likely benign	rs143600441	RCV000720995
Non-syndromic X-linked intellectual disability	Uncertain significance; Benign	rs773751585, rs779869307	RCV000388951 RCV000323102 RCV000267990 RCV000357791
Nonpapillary renal cell carcinoma	Uncertain significance	rs868613900	RCV005899814
Schizophrenia	Uncertain significance	rs2518852572	RCV002463528

Show/Hide Text Mining Associations (22)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Addison Disease	Associate	27087023
Adrenal Hyperplasia Congenital	Associate	12940459
Asthma	Associate	28120837
Atkin syndrome	Inhibit	33774333
Autism Spectrum Disorder	Associate	20479760, 25305082
Chromosome Disorders	Associate	12940459
Congenital Abnormalities	Associate	21933724, 25305082
Depressive Disorder Major	Associate	27440233
Developmental Disabilities	Associate	27761175
Genetic Diseases Inborn	Associate	36318984
Glomerulonephritis IGA	Associate	22318827
Hypoadrenocorticism Familial	Associate	12940459, 22456342
Hypoadrenocorticism Familial	Stimulate	27761175
Intellectual Disability	Associate	10882729, 12940459, 21933724, 22456342, 25305082, 30103804, 33774333, 34452636
Mental Disorders	Associate	27440233, 36318984
Mental Retardation X Linked	Associate	33774333
Mental Retardation X Linked Nonsyndromic	Associate	21933724, 36318984
Mood Disorders	Associate	27440233
Neoplasms	Inhibit	22928040
Neoplasms	Associate	35292515
Neurologic Manifestations	Associate	30103804
Schizophrenia	Associate	20479760

IL1RAPL1 (interleukin 1 receptor accessory protein like 1)