IL1RAPL1 (interleukin 1 receptor accessory protein like 1)

Gene

• Entrez ID: 11141
• Gene name: Interleukin 1 receptor accessory protein like 1
• Gene symbol: IL1RAPL1
• Synonyms (NCBI Gene): IL-1-RAPL-1, IL-1RAPL-1, IL1R8, IL1RAPL, IL1RAPL-1, MRX10, MRX21, MRX34, OPHN4, TIGIRR-2
• Chromosome: X
• Chromosome location: Xp21.3-p21.2
• Summary: The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane do

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs122461160	C>A	Pathogenic	Coding sequence variant, stop gained
rs122461161	G>A	Pathogenic	Coding sequence variant, stop gained
rs878853146	TTGGGAAAGT>-	Pathogenic	Frameshift variant, coding sequence variant
rs886041775	G>A	Pathogenic	Splice donor variant
rs1064795372	AGA>-	Likely-pathogenic, not-provided	Coding sequence variant, inframe deletion
rs1569203705	C>T	Pathogenic	Coding sequence variant, stop gained

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT053613	hsa-miR-151a-5p	Luciferase reporter assay, qRT-PCR, Western blot	22928040
MIRT721948	hsa-miR-100-3p	HITS-CLIP	19536157
MIRT721947	hsa-miR-4279	HITS-CLIP	19536157
MIRT721946	hsa-miR-3161	HITS-CLIP	19536157
MIRT721945	hsa-miR-599	HITS-CLIP	19536157
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	19536157
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	19536157
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	22927820
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	22927820
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	22927820
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT674564	hsa-miR-5197-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT628093	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT628092	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT628091	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628090	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	24906430
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	24906430
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	24906430
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	24906430
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	24906430
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	24906430
MIRT523020	hsa-miR-8485	PAR-CLIP	23446348
MIRT523019	hsa-miR-6768-5p	PAR-CLIP	23446348
MIRT523018	hsa-miR-4307	PAR-CLIP	23446348
MIRT628095	hsa-miR-147a	HITS-CLIP	27418678
MIRT628095	hsa-miR-147a	HITS-CLIP	27418678
MIRT575315	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT575315	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT575314	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT575314	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	27418678
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	27418678
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	27418678
MIRT628101	hsa-miR-3911	HITS-CLIP	27418678
MIRT628101	hsa-miR-3911	HITS-CLIP	27418678
MIRT575311	hsa-miR-3941	HITS-CLIP	27418678
MIRT575311	hsa-miR-3941	HITS-CLIP	27418678
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	27418678
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	27418678
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	27418678
MIRT628094	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT628094	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT575313	hsa-miR-603	HITS-CLIP	27418678
MIRT575313	hsa-miR-603	HITS-CLIP	27418678
MIRT628100	hsa-miR-644a	HITS-CLIP	27418678
MIRT628100	hsa-miR-644a	HITS-CLIP	27418678
MIRT628102	hsa-miR-663b	HITS-CLIP	27418678
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	27418678
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	27418678
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	27418678
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	27418678
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	27418678
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	27418678
MIRT523020	hsa-miR-8485	HITS-CLIP	27418678
MIRT523020	hsa-miR-8485	HITS-CLIP	27418678
MIRT721948	hsa-miR-100-3p	HITS-CLIP	19536157
MIRT721947	hsa-miR-4279	HITS-CLIP	19536157
MIRT721946	hsa-miR-3161	HITS-CLIP	19536157
MIRT721945	hsa-miR-599	HITS-CLIP	19536157
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	19536157
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	19536157
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	22927820
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	22927820
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	22927820
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT674564	hsa-miR-5197-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT628102	hsa-miR-663b	HITS-CLIP	23824327
MIRT628101	hsa-miR-3911	HITS-CLIP	23824327
MIRT628100	hsa-miR-644a	HITS-CLIP	23824327
MIRT628099	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628098	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT628097	hsa-miR-588	HITS-CLIP	23824327
MIRT628096	hsa-miR-7108-5p	HITS-CLIP	23824327
MIRT628095	hsa-miR-147a	HITS-CLIP	23824327
MIRT628094	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT575315	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575314	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575313	hsa-miR-603	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT575311	hsa-miR-3941	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT606794	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT606793	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT606792	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	HITS-CLIP	23824327
MIRT523019	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT523018	hsa-miR-4307	HITS-CLIP	23824327
MIRT523020	hsa-miR-8485	PAR-CLIP	23446348
MIRT523019	hsa-miR-6768-5p	PAR-CLIP	23446348
MIRT523018	hsa-miR-4307	PAR-CLIP	23446348
MIRT1064396	hsa-miR-1269	CLIP-seq
MIRT1064397	hsa-miR-1269b	CLIP-seq
MIRT1064398	hsa-miR-1288	CLIP-seq
MIRT1064399	hsa-miR-3158-5p	CLIP-seq
MIRT1064400	hsa-miR-3654	CLIP-seq
MIRT1064401	hsa-miR-378	CLIP-seq
MIRT1064402	hsa-miR-378b	CLIP-seq
MIRT1064403	hsa-miR-378c	CLIP-seq
MIRT1064404	hsa-miR-378d	CLIP-seq
MIRT1064405	hsa-miR-378e	CLIP-seq
MIRT1064406	hsa-miR-378f	CLIP-seq
MIRT1064407	hsa-miR-378h	CLIP-seq
MIRT1064408	hsa-miR-378i	CLIP-seq
MIRT1064409	hsa-miR-422a	CLIP-seq
MIRT1064410	hsa-miR-4269	CLIP-seq
MIRT1064411	hsa-miR-4418	CLIP-seq
MIRT1064412	hsa-miR-4515	CLIP-seq
MIRT1064413	hsa-miR-4645-5p	CLIP-seq
MIRT1064414	hsa-miR-4673	CLIP-seq
MIRT1064415	hsa-miR-4740-5p	CLIP-seq
MIRT1064416	hsa-miR-509-3-5p	CLIP-seq
MIRT1064417	hsa-miR-509-5p	CLIP-seq
MIRT2015297	hsa-miR-1915	CLIP-seq
MIRT2015298	hsa-miR-2964a-5p	CLIP-seq
MIRT2015299	hsa-miR-4714-3p	CLIP-seq
MIRT2015300	hsa-miR-4726-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005102	Function	Signaling receptor binding	ISS
GO:0005515	Function	Protein binding	IPI	12783849, 21940441
GO:0005737	Component	Cytoplasm	IEA
GO:0005886	Component	Plasma membrane	IDA	12783849
GO:0005886	Component	Plasma membrane	TAS
GO:0007157	Process	Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	ISS
GO:0007165	Process	Signal transduction	IEA
GO:0009986	Component	Cell surface	ISS
GO:0010975	Process	Regulation of neuron projection development	ISS
GO:0016021	Component	Integral component of membrane	IEA
GO:0019966	Function	Interleukin-1 binding	IDA	12783849
GO:0030182	Process	Neuron differentiation	ISS
GO:0030424	Component	Axon	IEA
GO:0030425	Component	Dendrite	ISS
GO:0045211	Component	Postsynaptic membrane	NAS	21940441
GO:0045920	Process	Negative regulation of exocytosis	IBA	21873635
GO:0045920	Process	Negative regulation of exocytosis	IDA	12783849
GO:0050135	Function	NAD(P)+ nucleosidase activity	IEA
GO:0050775	Process	Positive regulation of dendrite morphogenesis	ISS
GO:0051965	Process	Positive regulation of synapse assembly	ISS
GO:0061809	Function	NAD+ nucleotidase, cyclic ADP-ribose generating	IEA
GO:0071345	Process	Cellular response to cytokine stimulus	TAS
GO:0097105	Process	Presynaptic membrane assembly	ISS
GO:0098978	Component	Glutamatergic synapse	IDA	21926414
GO:0098978	Component	Glutamatergic synapse	IMP	21926414
GO:0099175	Process	Regulation of postsynapse organization	IDA	21926414
GO:0099175	Process	Regulation of postsynapse organization	IMP	21926414
GO:0099545	Process	Trans-synaptic signaling by trans-synaptic complex	IDA	21926414
GO:0099545	Process	Trans-synaptic signaling by trans-synaptic complex	IMP	21926414
GO:1905606	Process	Regulation of presynapse assembly	IDA	21926414
GO:1905606	Process	Regulation of presynapse assembly	IMP	21926414

Other IDs

• MIM: 300206
• HGNC: 5996
• e!Ensembl: ENSG00000169306

Protein

• UniProt ID: Q9NZN1
• Protein name: Interleukin-1 receptor accessory protein-like 1 (IL-1-RAPL-1) (IL-1RAPL-1) (IL1RAPL-1) (EC 3.2.2.6) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2) (X-linked interleukin-1 receptor accessory protein-like 1)
• Protein function: May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel (PubMed:12783849). May activate the MAP kinase JNK (PubMed:15123616). Plays a role in neurite outgrowth (By similar
• PDB: 1T3G, 4M92, 5WY8
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF18452	Ig_6	92 → 143	Immunoglobulin domain	Domain
  PF00047	ig	251 → 348	Immunoglobulin domain	Domain
  PF01582	TIR	404 → 579	TIR domain	Family

• Tissue specificity: TISSUE SPECIFICITY: Detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. Detected at very low levels in tonsil, prostate, testis, small intestine, placenta,
• Sequence:

  MKAPIPHLILLYATFTQSLKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYI
  RTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVI
  RNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEIL
  WYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDK
  PPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWE
  SDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVEL
  AGGLGAILLLLVCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWN
  QETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPN
  YVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTVIKWH
  GPKCNKLNSKFWKRLQYEMPFKRIEPITHEQALDVSEQGPFGELQTVSAISMAAATSTAL
  ATAHPDLRSTFHNTYHSQMRQKHYYRSYEYDVPPTGTLPLTSIGNQHTYCNIPMTLINGQ
  RPQTKSSREQNPDEAHTNSAILPLLPRETSISSVIW

• Sequence length: 696

Pathways

Reactome:

Receptor-type tyrosine-protein phosphatases
Interleukin-38 signaling

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Attention deficit hyperactivity disorder	Attention deficit hyperactivity disorder	rs786205019
Autism spectrum disorder	Autism Spectrum Disorders	rs724159978, rs75184679, rs119103221, rs9332964, rs121912562, rs1594344233, rs727504317, rs111033204, rs1801086, rs587784464, rs724159948, rs764659822, rs794727977, rs796052733, rs796052728, rs762292772, rs864321694, rs869312878, rs758432471, rs750896617, rs886039692, rs886039770, rs201037487, rs200483989, rs1057518198, rs1057517708, rs780267761, rs1555910143, rs1057519632, rs775225727, rs751037529, rs1064794848, rs1064795655, rs1131691548, rs1135401811, rs1553248081, rs1454466097, rs1554480537, rs1553578503, rs1553518509, rs774152851, rs1554481395, rs1554464807, rs1554401434, rs1561824498, rs1396313317, rs1564801388, rs1564801473, rs1564950387, rs1565527302, rs1569513495, rs1569305431, rs143944436, rs1563183492, rs1561846159, rs1565819425, rs1562957809, rs1585645641, rs1585016242, rs1595127294, rs1585667374, rs1585653028, rs1585653240, rs1592919048, rs1585645384, rs1789927813	20479760
Autism	Autistic Disorder, Autistic behavior	rs121964908, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699, rs1553510219, rs1684182454, rs1559060428, rs1553510677, rs1576352885, rs1574152522, rs1574152672, rs1696658542	18801879, 20437600
Developmental delay	Global developmental delay	rs28941770, rs199469464, rs281865469, rs143747297, rs398123009, rs587777428, rs786205133, rs606231459, rs797044854, rs797045027, rs864309504, rs878853160, rs886039902, rs886042046, rs886041291, rs886041382, rs1057518991, rs1057518699, rs753254213, rs748294403, rs762552974, rs1135401795, rs1553121073, rs1553122926, rs1364690005, rs1554086554, rs1554210415, rs1554168326, rs1554776342, rs1553873247, rs1567860112, rs779009256, rs1557447255, rs1564568350, rs780011005, rs1597464953, rs1200336864, rs1569513017, rs1587459606, rs1570332505, rs748888652, rs1575155995, rs2087029320, rs1589669105, rs1601769604, rs1184981709, rs749201074
Mental retardation	Severe intellectual disability, Mental Retardation, Moderate intellectual disability, MENTAL RETARDATION, X-LINKED 34 (disorder), Mental Retardation, X-Linked	rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315, rs121918316, rs397515320, rs121434489, rs1585215916, rs267607233, rs267606752, rs137852214, rs606231193, rs132630297, rs80338758, rs137852815, rs122455132, rs28935171, rs122453113, rs122445108, rs28934904, rs28934908, rs28935468, rs61748421, rs121918624, rs202060209, rs80338708, rs113994198, rs199422192, rs387906635, rs1554770064, rs1057519611, rs1060499526, rs387906636, rs1057519612, rs281875189, rs281875322, rs387906799, rs387906804, rs875989800, rs797045262, rs387906845, rs387906846, rs876657378, rs281875227, rs281875228, rs281875229, rs281875230, rs387906861, rs370667926, rs387906932, rs387906943, rs1557612719, rs387907190, rs387907191, rs2126499522, rs587776908, rs1560982564, rs80359505, rs398123009, rs587776929, rs587776930, rs397514555, rs398122824, rs398122825, rs397514556, rs2147483647, rs587776937, rs397514627, rs397514655, rs397514656, rs730882192, rs1587520018, rs1581995953, rs1554121970, rs1581987445, rs397514670, rs376395543, rs137854128, rs397509411, rs397509412, rs397514741, rs398122394, rs879255516, rs397518483, rs398122406, rs398122412, rs398123561, rs200667343, rs587777162, rs587777202, rs62507350, rs587777219, rs587777225, rs587777226, rs587779750, rs587777326, rs587777334, rs281875332, rs587780470, rs587780474, rs587780486, rs587777378, rs587777406, rs587777408, rs587777409, rs587777411, rs587777522, rs527236034, rs527236035, rs267608571, rs267608382, rs267608597, rs61753979, rs61751444, rs267608493, rs587777644, rs587777645, rs587777646, rs587777703, rs587779388, rs606231266, rs606231267, rs672601340, rs606231268, rs672601341, rs606231269, rs672601342, rs606231270, rs606231271, rs606231272, rs606231273, rs587784566, rs587784092, rs587783749, rs587783747, rs587783640, rs587783483, rs606231456, rs606231457, rs606231458, rs606231459, rs672601370, rs672601369, rs672601371, rs672601367, rs672601366, rs672601365, rs672601364, rs672601363, rs672601362, rs672601376, rs672601377, rs672601378, rs724159949, rs724159950, rs724159948, rs724159956, rs724159953, rs727502860, rs727502861, rs730882197, rs749995448, rs786205143, rs794726770, rs1135401808, rs786205583, rs786205595, rs786205859, rs794727792, rs794727928, rs794729221, rs797044519, rs797044523, rs797044521, rs797044524, rs797044526, rs797044522, rs797044520, rs794727642, rs796052719, rs781746113, rs796052510, rs796052733, rs796052724, rs796052728, rs796052676, rs796053353, rs796053366, rs796053368, rs1555103986, rs1555110818, rs796052571, rs1555110843, rs796052626, rs796052618, rs796053290, rs796052217, rs672601368, rs797045164, rs797044961, rs797044962, rs200070245, rs797044963, rs869320675, rs869320676, rs797045012, rs752746786, rs797044885, rs797044925, rs797044854, rs797044849, rs797044930, rs797044901, rs797044918, rs797044884, rs797045177, rs797045178, rs797045050, rs797045036, rs797045053, rs797045047, rs797045037, rs797045042, rs797045041, rs879255261, rs782397980, rs797045263, rs797045264, rs797045655, rs797045586, rs545185248, rs797046031, rs797046028, rs797046029, rs797046030, rs797045249, rs797045529, rs797045952, rs797045984, rs797045540, rs797045539, rs797045989, rs863224930, rs869025202, rs863225264, rs863225077, rs876661308, rs869025222, rs864309560, rs758252808, rs745756308, rs869025286, rs869025287, rs869025578, rs143038880, rs869025579, rs869025580, rs869025581, rs869312704, rs869312674, rs869312677, rs869312689, rs869312693, rs869312698, rs869312708, rs869312711, rs869312826, rs869312825, rs869312824, rs869312823, rs758432471, rs869312821, rs761993070, rs869312844, rs869312842, rs869312843, rs869312841, rs869312847, rs869320632, rs869312955, rs773432002, rs869320713, rs869320772, rs869320773, rs879255270, rs875989848, rs875989849, rs1716457622, rs2108414289, rs878854401, rs875989786, rs1085307109, rs1085307108, rs876657679, rs876661167, rs876661076, rs876661055, rs876661219, rs876661064, rs876661151, rs876661041, rs200440467, rs876661295, rs878853045, rs878853143, rs878853142, rs878853149, rs1555910048, rs878853152, rs878853146, rs878853145, rs878853141, rs878853151, rs878853144, rs878853148, rs878853147, rs878853251, rs878853269, rs879253762, rs886037841, rs879253888, rs879253931, rs879254016, rs879255618, rs879255619, rs879255620, rs886037847, rs879255621, rs886039332, rs746177928, rs886039520, rs886041003, rs886041058, rs750035706, rs886041059, rs886041060, rs886041061, rs886041090, rs886041088, rs886041089, rs886041095, rs886041097, rs886041989, rs886041944, rs886041692, rs886041593, rs886041687, rs886041207, rs886041309, rs886041239, rs886041448, rs138336847, rs149644940, rs886041295, rs886041521, rs886041125, rs886042041, rs886041238, rs886041469, rs886041197, rs886041291, rs886041658, rs886041705, rs886041876, rs139716296, rs1057516030, rs1057517408, rs749655461, rs141179774, rs370916968, rs1057517676, rs1057517933, rs1057517708, rs1057518352, rs1057518183, rs1057518474, rs1057518204, rs1057517825, rs1057518796, rs1057518961, rs1057518772, rs1057518988, rs1057519004, rs1057518700, rs772450541, rs371310428, rs1057519019, rs1057519491, rs1057519546, rs1057519560, rs1057519565, rs1057519400, rs1057519402, rs1057519405, rs1057519593, rs1057519594, rs1057519628, rs1556912828, rs1060505029, rs1060505030, rs147001633, rs1057519947, rs1057519617, rs1057524832, rs774592932, rs797045045, rs1039571136, rs1555910821, rs1060499626, rs1060499655, rs1554770185, rs1060499936, rs1060501153, rs1060501151, rs1064792984, rs1060503378, rs1060503386, rs1060503383, rs1060500046, rs1064792999, rs1060505033, rs1064796564, rs1064797002, rs1064793161, rs150802299, rs1064796830, rs1064794996, rs1064795444, rs1064796034, rs1064796403, rs1064794979, rs1064796765, rs1064793539, rs760933323, rs1064793546, rs1064796406, rs1064796367, rs780441716, rs1064794894, rs1064796023, rs1064797355, rs1085307484, rs1064794935, rs1085307547, rs1131690804, rs757511770, rs1131691875, rs1131691979, rs398122823, rs1131691866, rs1131692159, rs1131692228, rs1131692154, rs113331868, rs1554121872, rs1554121875, rs926027867, rs1554122123, rs1554122129, rs1287121256, rs1554122526, rs1554123982, rs1554385102, rs1554385111, rs1554385305, rs1554386687, rs1554389088, rs1554402092, rs1554434435, rs1135401778, rs1135401760, rs1135401770, rs1135401771, rs1135401768, rs1135401779, rs1135401805, rs1135401797, rs1135401799, rs1135401816, rs1135401823, rs1135401824, rs1555769968, rs1135401825, rs1135401955, rs1135401956, rs1135401957, rs1135401958, rs1554129040, rs1554150543, rs1553188463, rs1553146165, rs1485978447, rs1361547443, rs750079325, rs369692236, rs1554231836, rs749188610, rs1554122735, rs1554689877, rs1174482090, rs781053477, rs1554623112, rs1555409836, rs1555411305, rs770014321, rs1555984461, rs1555990958, rs762292772, rs1554944271, rs1057524157, rs1485749468, rs1555984343, rs1293450628, rs373584239, rs1553722309, rs1553738686, rs1376334317, rs1553722294, rs1553283831, rs1554120589, rs1555985554, rs1555877287, rs1555411378, rs750922282, rs1553264873, rs1554263326, rs1554264268, rs1554263626, rs1554263625, rs766614772, rs1553620494, rs1555050158, rs1555050165, rs1555050171, rs1555050174, rs765556214, rs1402086660, rs1554645052, rs1555661648, rs1293246328, rs749494995, rs775592405, rs1553265189, rs1553242856, rs1553247374, rs1553241570, rs1553997065, rs1553998565, rs1380822792, rs1555028154, rs1555023232, rs1553194155, rs1553130904, rs1553152590, rs1553567864, rs1553638614, rs120074160, rs1554486894, rs1554767754, rs1554843977, rs1555443581, rs1555443600, rs1555439545, rs1555525088, rs770680174, rs1555889130, rs373178770, rs1555985532, rs1553519853, rs781325598, rs1410587479, rs1553638086, rs150259543, rs1554093891, rs1554121228, rs1554120498, rs1554121189, rs1212517874, rs1554770628, rs1555979158, rs1554770054, rs771610568, rs1451230055, rs1554770624, rs1555906707, rs1555906768, rs1555906781, rs1555907620, rs1555907623, rs1555907626, rs1555907653, rs1555907864, rs1554094145, rs1554202698, rs1554200722, rs773327091, rs1555607621, rs1555604778, rs1555607159, rs1555607682, rs1553364018, rs1553324416, rs1555411394, rs1554102556, rs1554122363, rs1555705966, rs1555103971, rs1555408401, rs1554461593, rs1554304254, rs1554120978, rs1047509819, rs1555982601, rs767774867, rs1554789246, rs1555111511, rs1555950676, rs1555954380, rs1555985649, rs1553194162, rs1553518509, rs1274633498, rs1554274371, rs1554122252, rs1554122458, rs1554122729, rs1554297905, rs1554776342, rs1554770046, rs1554770667, rs1554792556, rs1452715535, rs1555444885, rs1555534147, rs1427624649, rs1555611722, rs1555744282, rs1555706391, rs1178702025, rs1555984102, rs1554770589, rs1554121443, rs1559791842, rs1559824939, rs1555889127, rs1236702036, rs1553510280, rs1553511175, rs1553511226, rs1554150552, rs1554275163, rs1554201137, rs1553517991, rs1553518511, rs1553517984, rs1553518752, rs1554119814, rs1554122293, rs1554122341, rs1554122689, rs1554770243, rs1554770444, rs1557045250, rs959316981, rs1556270312, rs1553270640, rs978179634, rs1554093884, rs1491240980, rs1555943484, rs1554121453, rs1334099693, rs1554048616, rs1555660806, rs1555644480, rs1555651572, rs1567844992, rs1567855081, rs1567855669, rs1567855704, rs1567856045, rs1567856331, rs1567860075, rs1567860112, rs1567860640, rs1567860891, rs754919272, rs1567860919, rs1567861468, rs1567861489, rs1567861501, rs1567861894, rs1567863732, rs1567864750, rs1567877108, rs1567878511, rs758785463, rs1553808301, rs1553245038, rs1553789166, rs1553813646, rs1553631860, rs1554121265, rs1554770262, rs1555034768, rs1555984433, rs779009256, rs1553994814, rs1553996086, rs1553996072, rs1553270599, rs1553153291, rs760262127, rs1554119274, rs1554121878, rs1554387293, rs1554385203, rs757077698, rs750612085, rs1554776500, rs1564360978, rs1554776933, rs1554776938, rs1565278132, rs1567368243, rs1558478047, rs375695605, rs1558479778, rs1558501648, rs1565240833, rs114727354, rs1557591264, rs1557620758, rs1559099927, rs1561788984, rs369459721, rs1563831738, rs1562159088, rs1562159562, rs1562159599, rs1559094754, rs1559328283, rs755634856, rs1561784687, rs1554122296, rs1561789313, rs1562720119, rs1564363665, rs1561697465, rs1561785003, rs1561787845, rs1561789215, rs1554122305, rs1561784553, rs1561784560, rs1561787690, rs1554122888, rs749632782, rs1567139896, rs1569370887, rs1569371303, rs1564493599, rs1561875779, rs1569146542, rs1569146649, rs1275489527, rs1560115921, rs1468772495, rs749969789, rs1560108090, rs1569376809, rs1569355102, rs1560103306, rs1564365418, rs1559855453, rs1562928193, rs1558149913, rs1253072668, rs141976414, rs1558371790, rs1557898800, rs1567758622, rs1567844041, rs1567844114, rs1567920106, rs1567920209, rs138247472, rs1567974030, rs1567995650, rs1283838287, rs1568003569, rs1568006217, rs1568018905, rs1562505675, rs1561783309, rs1555980234, rs1559087186, rs1560966086, rs1560330387, rs769471341, rs1562493608, rs1562505335, rs1554121861, rs1554122200, rs1562957809, rs1568097623, rs1391600900, rs1568234874, rs1568235086, rs1555990955, rs1567870541, rs1557570794, rs1562869207, rs1571818248, rs1431778557, rs369691608, rs1595808957, rs1597665063, rs1597846084, rs1603401125, rs1603350606, rs1601946481, rs1601932069, rs1602880906, rs1602308324, rs1574554519, rs1573882268, rs1603198937, rs1558148010, rs1558498928, rs1569459580, rs1569380375, rs1560062082, rs1557889974, rs1558414255, rs756429763, rs781663444, rs1569016820, rs1569017025, rs1569017160, rs1557612048, rs1568504941, rs1581987022, rs1576983339, rs1599892470, rs1265340906, rs1602284689, rs1574949440, rs1576220938, rs1576280892, rs1576288424, rs1574459612, rs1574511051, rs1575654528, rs1577094794, rs1294683568, rs771819481, rs1580984895, rs1581338441, rs1580988138, rs1581980317, rs1581986872, rs1554121207, rs1581987268, rs1581987476, rs1581987885, rs763770519, rs1581991929, rs1581992099, rs1581992998, rs1581995453, rs1554122242, rs1581996778, rs1581997228, rs1588735247, rs1555980467, rs1555985742, rs1601319086, rs1601970168, rs1574451881, rs876661168, rs1576994053, rs1573589807, rs1581036396, rs1601267617, rs1572531830, rs1573483715, rs1590954686, rs1601315812, rs1573965358, rs1573972562, rs529087882, rs1570609440, rs1598940393, rs1575333081, rs1576028676, rs1596476657, rs1599375711, rs1603290366, rs1603060007, rs1603069440, rs1592939069, rs1591612223, rs2062994512, rs373701249, rs1600471396, rs1600501018, rs1600504088, rs1600514073, rs748436953, rs765723607, rs758170522, rs1561785045, rs1357591960, rs1591609136, rs1596891223, rs1579370234, rs2047850664, rs1579109565, rs1870202051, rs1574887674, rs778229060, rs1572531281, rs1570622663, rs1573501865, rs1576086299, rs1576164991, rs1574907198, rs1576656734, rs1554121438, rs1581995425, rs1581996813, rs1582001015, rs1588324025, rs1591371152, rs1590008294, rs1590956245, rs1590028691, rs1591606580, rs1591611001, rs1591612317, rs1591612370, rs763436882, rs997044541, rs1595897117, rs747706524, rs1579377990, rs1201878175, rs1894051550, rs1572531730, rs1579576029, rs1577017863, rs752545577, rs1582461267, rs1589460606, rs1588727276, rs1598620094, rs1599368323, rs1600082188, rs1601319352, rs1598226304, rs2076013475, rs2076017638, rs1600596180, rs1554121932, rs1680676671, rs1570607996, rs1382444181, rs1570640673, rs1574994308, rs1596667777, rs1602226289, rs1595629181, rs1595609005, rs1227643933, rs1572705473, rs1570621899, rs1722830922, rs1575094649, rs1417035592, rs1581997098, rs1589457762, rs1598211790, rs758726258, rs1601071971, rs863224922, rs1586692481, rs1586692548, rs1586692551, rs1580988074, rs1594129609, rs1588732344, rs1579368865, rs1586660389, rs1586660370, rs1586660338, rs1586657848, rs1586660381, rs1791701214, rs752676391, rs1680673822, rs758098717, rs1726676630, rs762288077, rs1759964009, rs1760905766, rs1761021165, rs1554121934, rs2055849544, rs1049773, rs587784300, rs1861628072, rs1761241410, rs1064797322, rs1948652423, rs2059194330, rs1777174302, rs2054280202, rs2081190512, rs772665884, rs1400164869, rs1861593395, rs1760897843, rs1761087122, rs1388355040, rs2068797192, rs1777175608, rs376898131	24680889, 28576939, 19012350, 18801879, 16470793, 10471494
Macrocephaly	Macrocephaly	rs786204854, rs764333096, rs1557739557
Melanoma	melanoma	rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340, rs398123152, rs587780668, rs587782083, rs587782206, rs587782792, rs180177042, rs121913381, rs730881675, rs730881674, rs730881677, rs730881673, rs1800586, rs768966657, rs587778189, rs786204195, rs121913321, rs45476696, rs864622636, rs864622263, rs869025340, rs876660436, rs876658534, rs876658556, rs878853647, rs878853644, rs878853650, rs886041162, rs121913389, rs1057519852, rs121913384, rs121913387, rs1060501266, rs1060501263, rs1060501262, rs749714198, rs1060501265, rs559848002, rs1064794292, rs1131691187, rs1131691186, rs199907548, rs1554654052, rs1554656411, rs1554656624, rs1554653915, rs1554653956, rs1554656253, rs1554654224, rs754806883, rs1057520039, rs1563889584, rs1563889685, rs1287464120, rs1563888944, rs1563892715, rs1563889847, rs141798398, rs1587332338, rs1587340291, rs11552823, rs561034503, rs138677674, rs1819962958, rs1820531050	22535842
Mental retardation, x-linked	Mental Retardation, X-Linked 1	rs1603009115, rs199422240, rs199422234, rs782600511, rs199422235, rs199422236, rs199422237, rs199422238, rs199422239, rs2147483647, rs137852561, rs104894952, rs137852350, rs137852351, rs137852352, rs587776734, rs267606995, rs121918525, rs121918526, rs606231182, rs606231183, rs137852214, rs137852215, rs121918522, rs121918523, rs121918524, rs121918521, rs730882185, rs730882186, rs137853272, rs267607187, rs267607189, rs267607188, rs1602048836, rs1602048728, rs1328291159, rs28936077, rs121434615, rs121434616, rs786200913, rs1603370185, rs122468181, rs122468182, rs122461160, rs122461161, rs1373474125, rs137852815, rs387906499, rs122458138, rs1569423317, rs122458139, rs121434611, rs121434612, rs121434613, rs121434614, rs397515381, rs121434610, rs267607076, rs121434608, rs121434609, rs104894950, rs122454129, rs61748421, rs398122813, rs387906703, rs398122814, rs398122844, rs387906704, rs387906705, rs398122846, rs398122847, rs398122854, rs387906728, rs281860639, rs387906729, rs397515550, rs397515551, rs397518478, rs397518479, rs397515553, rs587777161, rs587777261, rs587777317, rs587777318, rs587777359, rs587777360, rs587777361, rs587780372, rs1555949612, rs267608329, rs61754457, rs587777605, rs267608465, rs786205133, rs606231282, rs587783357, rs587783360, rs587783361, rs587783362, rs587783364, rs587783366, rs587783368, rs587783370, rs587783371, rs137929307, rs727503977, rs727505397, rs786205208, rs794727270, rs139990565, rs794727881, rs796052231, rs796052232, rs796052234, rs796052235, rs796052236, rs796052230, rs796052226, rs797045024, rs797045025, rs869320681, rs797045026, rs797044862, rs797045140, rs879255583, rs879255584, rs797045920, rs797045433, rs749742837, rs797045431, rs782246658, rs797045646, rs863224854, rs863224879, rs864321627, rs864321628, rs864321631, rs869025343, rs869025344, rs869025345, rs869025588, rs869025589, rs869025590, rs869025591, rs869025592, rs752738546, rs875989829, rs869312692, rs1555988417, rs886039763, rs886039764, rs875989799, rs875989803, rs875989802, rs876661316, rs878853055, rs758719615, rs878854425, rs1569309474, rs1569309776, rs1569309459, rs1923775114, rs1569233549, rs1569230006, rs1569231897, rs886037836, rs1114167352, rs1929024034, rs886038208, rs886038209, rs886038210, rs886038211, rs886041767, rs886041481, rs886041705, rs886041876, rs886041701, rs886041595, rs886041433, rs886041774, rs886041971, rs1057518171, rs1057518019, rs1057518707, rs1057518697, rs1057518704, rs1057518729, rs1057518728, rs1057518730, rs1057518650, rs1057519431, rs1057519446, rs1057519430, rs1057519393, rs1057519396, rs1556909287, rs1556910184, rs1556912828, rs1556913180, rs1556913258, rs1556913268, rs782393002, rs1556955128, rs1556978515, rs1557006873, rs1557006903, rs1557024919, rs1557036757, rs1557036768, rs782099475, rs1057522024, rs1057520858, rs1057521657, rs1060499652, rs1060499661, rs1060499660, rs1060505032, rs1060505033, rs1064796023, rs1064794254, rs1064793796, rs1064796820, rs1064796827, rs1064795387, rs779508996, rs1064795512, rs1064793874, rs1085307760, rs1114167441, rs1131692155, rs1114167891, rs943295842, rs1131690786, rs1131691299, rs1131691887, rs1131691982, rs1131692040, rs1131692041, rs1131692042, rs1131692227, rs1135401788, rs1135401800, rs1135401762, rs1556014749, rs1556910261, rs1555972599, rs1556235551, rs1557314191, rs1555972628, rs1555980033, rs886128077, rs1556863435, rs1556016632, rs780775497, rs1555933969, rs1555953398, rs1555953819, rs1556016802, rs1556016731, rs1556016555, rs1555950011, rs1556518231, rs1555975458, rs1555986221, rs1556254569, rs904072058, rs1555953488, rs1064794574, rs1556861311, rs1555970404, rs1555981722, rs1556863398, rs1556865060, rs1556016292, rs1556016529, rs1556858912, rs1555932766, rs1556377028, rs1555930128, rs1556836399, rs1555974716, rs1556016224, rs1555981717, rs1556863340, rs1555954380, rs1556852362, rs1556220623, rs1555953548, rs1555954284, rs1556220029, rs1556206910, rs1555977199, rs1556863492, rs1555951993, rs1556880284, rs1555980523, rs1555924331, rs1555917927, rs1555954154, rs1556244406, rs1267519974, rs1555954105, rs1569335265, rs1569429756, rs374220843, rs1569302816, rs782660318, rs1569306724, rs1569309460, rs1569309816, rs1569309449, rs1569395541, rs1569288603, rs1569309484, rs1569057837, rs1569301036, rs1569290954, rs1569291699, rs1569300277, rs1569509136, rs1569394026, rs1569336024, rs1569203705, rs1569234653, rs1569291627, rs1602311804, rs1569238002, rs1569290395, rs1602220706, rs1569399945, rs1569389364, rs1569271378, rs1569271892, rs1569350993, rs1569277866, rs1569277899, rs1569295677, rs1569291261, rs1569380062, rs1603378331, rs1569261319, rs1569278313, rs1602284689, rs1602134459, rs1602424764, rs1602264294, rs1602291658, rs1602291861, rs1602383045, rs1602211123, rs1602279457, rs905353542, rs1602131859, rs1602131872, rs1602132216, rs1602183619, rs1602228596, rs1603305030, rs1602136369, rs1603377813, rs1602624914, rs1602134468, rs1602155923, rs1602183890, rs1602152230, rs1602387702, rs1602481623, rs1602506017, rs1602538353, rs1602624950, rs1603308066, rs1602577238, rs1602119305, rs1602126980, rs1602127262, rs1602220170, rs1602292205, rs1602424869, rs1602283534, rs1602293475, rs1602210960, rs1602147880, rs1601761445, rs1602122138, rs1602292076, rs1555988314, rs1602159841, rs1603371016, rs774419889, rs1602134248, rs1602135698, rs1602738933, rs1602385860, rs2031508845, rs1602550687, rs1602253509, rs1602231587, rs1602210346, rs1601957478, rs1602857000, rs1602511836, rs1019534975, rs1603379772, rs1924650670, rs1772040461, rs1602253464, rs2031389522, rs267608399, rs2074091750, rs2074369642, rs2074383129, rs2061745581, rs2073058023, rs1926795050, rs2080112579, rs2063908570, rs2063927503, rs2063923605, rs2063876114, rs2031456898	16470793, 19012350
Obesity	Obesity	rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562, rs121913564, rs193922650, rs193922685, rs193922687, rs751160202, rs747681609, rs1553400259, rs13447339, rs370479598, rs1554394014, rs1553174844, rs756232889, rs369841551, rs1557670950, rs1571321748, rs148538980, rs1572820988, rs1591461970, rs1419374563, rs745921568, rs144159890, rs1570714352, rs779783209, rs1573250294, rs1573254045, rs1580744791, rs1580746829
Schizophrenia	Schizophrenia and related disorders	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	21982423
Seizure	Tonic - clonic seizures	rs587784365, rs28939683, rs74315390, rs28939684, rs74315391, rs267607198, rs74315392, rs118192244, rs118192250, rs121917749, rs121917750, rs121917751, rs121917752, rs267606670, rs267607061, rs121912707, rs118192249, rs118192251, rs118192217, rs118192218, rs118192219, rs118192222, rs118192226, rs118192228, rs118192234, rs118192236, rs118192235, rs118192241, rs118192242, rs118192185, rs118192188, rs118192245, rs118192246, rs118192186, rs118192194, rs118192197, rs118192199, rs118192201, rs118192202, rs118192203, rs118192204, rs118192205, rs118192206, rs118192208, rs118192211, rs118192216, rs118192239, rs387906684, rs387906686, rs387906687, rs1596893185, rs387907126, rs387907281, rs397515405, rs587778771, rs730882067, rs730882073, rs397514579, rs397514582, rs587776976, rs398122394, rs121918784, rs121918751, rs121918735, rs398123588, rs587780450, rs61749751, rs587777620, rs727503974, rs730882124, rs794726710, rs794726697, rs794726799, rs794727444, rs794727740, rs796053166, rs794726825, rs796052676, rs796053219, rs796053220, rs796053228, rs796052653, rs759584387, rs796052650, rs796052641, rs796052626, rs796052623, rs796052663, rs796052615, rs796052802, rs797044999, rs797045047, rs797045942, rs797045941, rs118192212, rs797044938, rs777257591, rs864321712, rs879255652, rs886039268, rs886039517, rs886039529, rs199497486, rs886039496, rs886039903, rs886041300, rs769827124, rs886041339, rs886041591, rs587783092, rs1555850151, rs1057516123, rs1057516121, rs1057516115, rs1057516111, rs1057516106, rs1057516105, rs756921902, rs1057516089, rs1057516087, rs1057516080, rs1057516076, rs1060499544, rs1555850512, rs1057517919, rs118192231, rs1057520413, rs1060503101, rs1064796294, rs1064794981, rs1064794632, rs1064797245, rs1131691830, rs1131692231, rs1131691936, rs1554626549, rs1553579225, rs1553531385, rs121918736, rs1554898088, rs1553579282, rs763353895, rs1553463119, rs1554093891, rs77838305, rs1555408401, rs1554627439, rs1554097873, rs1555850403, rs1064794719, rs1315483224, rs1567134495, rs770187706, rs1057518555, rs1576983339, rs1574192005, rs1459374430, rs1586800133, rs1574641522, rs1572096837, rs1572630269, rs1574554892, rs1574556643, rs1574571769, rs1574641605, rs1574697769, rs1574716524, rs1574746733, rs1574746935, rs1574752700, rs1574754680, rs863225030, rs1601545088, rs1600714727, rs1371059392, rs1600767259, rs1339542565, rs1600785769, rs2065899210, rs1600732174, rs1162306056, rs879255709, rs1900111672, rs2066910297, rs1554122080, rs796052941, rs1600789325, rs2082695884, rs1737677036, rs1737495759, rs868389022, rs1737685202, rs1737672350, rs762737130

Unknown
Disease term	Disease name	Evidence	References	Source
Vitiligo	Vitiligo			GWAS
Neuroticism	Neuroticism			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Addison Disease	Associate	27087023
Adrenal Hyperplasia Congenital	Associate	12940459
Asthma	Associate	28120837
Atkin syndrome	Inhibit	33774333
Autism Spectrum Disorder	Associate	20479760, 25305082
Chromosome Disorders	Associate	12940459
Congenital Abnormalities	Associate	21933724, 25305082
Depressive Disorder Major	Associate	27440233
Developmental Disabilities	Associate	27761175
Genetic Diseases Inborn	Associate	36318984
Glomerulonephritis IGA	Associate	22318827
Hypoadrenocorticism Familial	Associate	12940459, 22456342
Hypoadrenocorticism Familial	Stimulate	27761175
Intellectual Disability	Associate	10882729, 12940459, 21933724, 22456342, 25305082, 30103804, 33774333, 34452636
Mental Disorders	Associate	27440233, 36318984
Mental Retardation X Linked	Associate	33774333
Mental Retardation X Linked Nonsyndromic	Associate	21933724, 36318984
Mood Disorders	Associate	27440233
Neoplasms	Inhibit	22928040
Neoplasms	Associate	35292515
Neurologic Manifestations	Associate	30103804
Schizophrenia	Associate	20479760