ZWINT (ZW10 interacting kinetochore protein)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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11130 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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ZW10 interacting kinetochore protein |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ZWINT |
Synonyms (NCBI Gene)
Gene synonyms aliases
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HZwint-1, KNTC2AP, SIP30, ZWINT1 |
Chromosome
Chromosome number
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10 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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10q21.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein l |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | O95229 | ||||||||||
Protein name | Outer kinetochore KNL1 complex subunit ZWINT (ZW10 interactor) (ZW10-interacting protein 1) (Zwint-1) | ||||||||||
Protein function | Acts as a component of the outer kinetochore KNL1 complex that serves as a docking point for spindle assembly checkpoint components and mediates microtubule-kinetochore interactions (PubMed:15094189, PubMed:15485811, PubMed:15824131, PubMed:1673 | ||||||||||
PDB | 8PPR | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 277 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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