ZWINT (ZW10 interacting kinetochore protein)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 11130 |
| Gene name | ZW10 interacting kinetochore protein |
| Gene symbol | ZWINT |
| Synonyms (NCBI Gene) |
HZwint-1KNTC2APSIP30ZWINT1
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| Chromosome | 10 |
| Chromosome location | 10q21.1 |
| Summary | This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein l |
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miRNA
miRNA information provided by mirtarbase database.
384
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
27
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O95229 | ||||||||||
| Protein name | Outer kinetochore KNL1 complex subunit ZWINT (ZW10 interactor) (ZW10-interacting protein 1) (Zwint-1) | ||||||||||
| Protein function | Acts as a component of the outer kinetochore KNL1 complex that serves as a docking point for spindle assembly checkpoint components and mediates microtubule-kinetochore interactions (PubMed:15094189, PubMed:15485811, PubMed:15824131, PubMed:1673 | ||||||||||
| PDB | 8PPR | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 277 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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