Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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1112
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Forkhead box N3 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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FOXN3 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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C14orf116, CHES1, PRO1635 |
Chromosome
Chromosome number
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14 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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14q31.3-q32.11 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, r |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Leukemia |
Leukemia, Myelocytic, Acute |
rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 |
27903959 |
Schizophrenia |
Schizophrenia |
rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 View all (12 more) |
21926974 |
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Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Hypertension |
Hypertension |
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GWAS |
Ovarian cancer |
Ovarian cancer |
Conditional KD of IL6 in the OCCA xenograft model delays tumor growth |
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GWAS, CBGDA |
Breast Cancer |
Breast Cancer |
Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients |
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GWAS, CBGDA |
Diabetes |
Diabetes |
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|
GWAS |
Heart Failure |
Heart Failure |
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|
GWAS |
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Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Adenocarcinoma of Lung |
Associate
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35441736 |
Breast Neoplasms |
Associate
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28805661 |
Carcinoma Basal Cell |
Associate
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32382535 |
Drug Related Side Effects and Adverse Reactions |
Stimulate
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36768681 |
Hyperglycemia |
Associate
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31543974 |
Hyperglycemic Hyperosmolar Nonketotic Coma |
Associate
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31543974 |
Leukemia Monocytic Acute |
Inhibit
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24727659 |
Leukemia Myeloid |
Associate
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24727659 |
Nasopharyngeal Carcinoma |
Associate
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33317407 |
Neoplasm Metastasis |
Associate
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28805661 |
Neoplasms |
Inhibit
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24403608, 24727659, 30150773, 32078244 |
Neoplasms |
Associate
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33850302 |
Pancreatic Neoplasms |
Associate
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36622275 |
Precursor T Cell Lymphoblastic Leukemia Lymphoma |
Inhibit
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32078244 |
Squamous Cell Carcinoma of Head and Neck |
Associate
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31364120 |
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