Gene Gene information from NCBI Gene database.
Entrez ID 1112
Gene name Forkhead box N3
Gene symbol FOXN3
Synonyms (NCBI Gene)
C14orf116CHES1PRO1635
Chromosome 14
Chromosome location 14q31.3-q32.11
Summary This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, r
miRNA miRNA information provided by mirtarbase database.
871
miRTarBase ID miRNA Experiments Reference
MIRT007196 hsa-miR-574-5p Luciferase reporter assayqRT-PCRWestern blot 23133627
MIRT030800 hsa-miR-21-5p Microarray 18591254
MIRT040561 hsa-miR-92b-3p CLASH 23622248
MIRT054204 hsa-miR-210-3p Luciferase reporter assayMicroarrayqRT-PCRWestern blot 23028679
MIRT610933 hsa-miR-890 HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
17
GO ID Ontology Definition Evidence Reference
GO:0000785 Component Chromatin ISA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific ISA
GO:0000987 Function Cis-regulatory region sequence-specific DNA binding IBA
GO:0003677 Function DNA binding IEA
GO:0003700 Function DNA-binding transcription factor activity IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
602628 1928 ENSG00000053254
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O00409
Protein name Forkhead box protein N3 (Checkpoint suppressor 1)
Protein function Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).
PDB 6NCE , 6NCM
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00250 Forkhead 113 200 Forkhead domain Domain
Sequence
MGPVMPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDEEL
TNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFS
CLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERS
QSIGKGSLWCIDPEYRQNLI
QALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIWPGSTFF
KRNGALLQDPDIDAASAMMLLNTPPEIQAGFPPGVIQNGARVLSRGLFPGVRPLPITPIG
VTAAMRNGITSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSS
SADDHYEFATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKK
RQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKG
QKEQKETTKN
Sequence length 490
Interactions View interactions