DIDO1 (death inducer-obliterator 1)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 11083 |
| Gene name | Death inducer-obliterator 1 |
| Gene symbol | DIDO1 |
| Synonyms (NCBI Gene) |
BYE1C20orf158DATF-1DATF1DIDO2DIDO3DIO-1DIO1dJ885L7.8
|
| Chromosome | 20 |
| Chromosome location | 20q13.33 |
| Summary | Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic sig |
|
miRNA
miRNA information provided by mirtarbase database.
303
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
|||||||||||||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q9BTC0 | ||||||||||||||||||||
| Protein name | Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1) | ||||||||||||||||||||
| Protein function | Putative transcription factor, weakly pro-apoptotic when overexpressed (By similarity). Tumor suppressor. Required for early embryonic stem cell development. ; [Isoform 2]: Displaces isoform 4 | ||||||||||||||||||||
| PDB | 2M3H , 4L7X | ||||||||||||||||||||
| Family and domains |
Pfam
|
||||||||||||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. | ||||||||||||||||||||
| Sequence |
|
||||||||||||||||||||
| Sequence length | 2240 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
|
Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
2
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||