DNAJB4 (DnaJ heat shock protein family (Hsp40) member B4)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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11080 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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DnaJ heat shock protein family (Hsp40) member B4 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DNAJB4 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CMYO21, CMYP21, DNAJW, DjB4, HLJ1 |
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Chromosome
Chromosome number
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1 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p31.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds inco |
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miRNA
miRNA information provided by mirtarbase database.
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| Transcription factors | |||||||
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q9UDY4 | |||||||||||||||
| Protein name | DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein) | |||||||||||||||
| Protein function | Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877). | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver. {ECO:0000269|PubMed:9546042}. | |||||||||||||||
| Sequence |
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| Sequence length | 337 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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