DUS4L (dihydrouridine synthase 4 like)

Gene

• Entrez ID: 11062
• Gene name: Dihydrouridine synthase 4 like
• Gene symbol: DUS4L
• Synonyms (NCBI Gene): DUS4, PP35
• Chromosome: 7
• Chromosome location: 7q22.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT023098	hsa-miR-124-3p	Microarray	18668037
MIRT947323	hsa-miR-1260	CLIP-seq
MIRT947324	hsa-miR-1260b	CLIP-seq
MIRT947325	hsa-miR-1283	CLIP-seq
MIRT947326	hsa-miR-1293	CLIP-seq
MIRT947327	hsa-miR-188-3p	CLIP-seq
MIRT947328	hsa-miR-216b	CLIP-seq
MIRT947329	hsa-miR-2278	CLIP-seq
MIRT947330	hsa-miR-3135	CLIP-seq
MIRT947331	hsa-miR-3145-5p	CLIP-seq
MIRT947332	hsa-miR-3152-5p	CLIP-seq
MIRT947333	hsa-miR-3156-3p	CLIP-seq
MIRT947334	hsa-miR-3618	CLIP-seq
MIRT947335	hsa-miR-3921	CLIP-seq
MIRT947336	hsa-miR-4301	CLIP-seq
MIRT947337	hsa-miR-4483	CLIP-seq
MIRT947338	hsa-miR-4649-3p	CLIP-seq
MIRT947339	hsa-miR-4653-5p	CLIP-seq
MIRT947340	hsa-miR-4773	CLIP-seq
MIRT947341	hsa-miR-4774-3p	CLIP-seq
MIRT947342	hsa-miR-508-5p	CLIP-seq
MIRT947343	hsa-miR-660	CLIP-seq
MIRT947344	hsa-miR-934	CLIP-seq
MIRT1980624	hsa-miR-1915	CLIP-seq
MIRT1980625	hsa-miR-193a-5p	CLIP-seq
MIRT947331	hsa-miR-3145-5p	CLIP-seq
MIRT1980626	hsa-miR-4314	CLIP-seq
MIRT1980627	hsa-miR-4726-3p	CLIP-seq
MIRT947342	hsa-miR-508-5p	CLIP-seq
MIRT1980628	hsa-miR-579	CLIP-seq
MIRT947344	hsa-miR-934	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002943	Process	TRNA dihydrouridine synthesis	IDA	34798057
GO:0002943	Process	TRNA dihydrouridine synthesis	IEA
GO:0008033	Process	TRNA processing	IEA
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0017150	Function	TRNA dihydrouridine synthase activity	IBA
GO:0017150	Function	TRNA dihydrouridine synthase activity	IEA
GO:0050660	Function	Flavin adenine dinucleotide binding	IEA
GO:0102266	Function	TRNA-dihydrouridine20a synthase activity	IEA
GO:0102267	Function	TRNA-dihydrouridine20b synthase activity	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: O95620
• Protein name: tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like (EC 1.3.1.90) (pp35) (tRNA-dihydrouridine synthase 4-like)
• Protein function: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01207	Dus	30 → 310	Dihydrouridine synthase (Dus)	Family

• Sequence:

  MKSDCMQTTICQERKKDPIEMFHSGQLVKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIV
  AADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRW
  AMAEGYGACLINKPELVQDMVKQVRNQVETPGFSVSIKIRIHDDLKRTVDLCQKAEATGV
  SWITVHGRTAEERHQPVHYDSIKIIKENMSIPVIANGDIRSLKEAENVWRITGTDGVMVA
  RGLLANPAMFAGYEETPLKCIWDWVDIALELGTPYMCFHQHLMYMMEKITSRQEKRVFNA
  LSSTSAIIDYLTDHYGI

• Sequence length: 317