Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
11057
Gene name Gene Name - the full gene name approved by the HGNC.
Abhydrolase domain containing 2, acylglycerol lipase
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ABHD2
Synonyms (NCBI Gene) Gene synonyms aliases
HS1-2, LABH2, PHPS1-2
Chromosome Chromosome number
15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q26.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a wide range of enzymes. The encoded protein is an acylglycerol lipase that catalyzes the hydrolysis of endocannabinoid arachidonoylglycerol from the
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT018354 hsa-miR-335-5p Microarray 18185580
MIRT051282 hsa-miR-16-5p CLASH 23622248
MIRT049598 hsa-miR-92a-3p CLASH 23622248
MIRT041909 hsa-miR-484 CLASH 23622248
MIRT705979 hsa-miR-8080 HITS-CLIP 23313552
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001669 Component Acrosomal vesicle IEA
GO:0003707 Function Nuclear steroid receptor activity IDA 26989199
GO:0004806 Function Triacylglycerol lipase activity IEA
GO:0005886 Component Plasma membrane IEA
GO:0005929 Component Cilium IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
612196 18717 ENSG00000140526
Protein
UniProt ID P08910
Protein name Monoacylglycerol lipase ABHD2 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 2) (Acetylesterase) (EC 3.1.1.6) (Lung alpha/beta hydrolase 2) (Progesterone-sensitive lipase) (EC 3.1.1.79) (Protein PHPS1-2)
Protein function Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane (PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00561 Abhydrolase_1 126 383 alpha/beta hydrolase fold Domain
Tissue specificity TISSUE SPECIFICITY: Present in sperm (at protein level). {ECO:0000269|PubMed:26989199}.
Sequence
Sequence length 425
Interactions View interactions
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