STON1 (stonin 1)

Gene

• Entrez ID: 11037
• Gene name: Stonin 1
• Gene symbol: STON1
• Synonyms (NCBI Gene): SALF, SBLF, STN1, STNB1
• Chromosome: 2
• Chromosome location: 2p16.3
• Summary: Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is rela

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1399042	hsa-miR-1260	CLIP-seq
MIRT1399043	hsa-miR-1260b	CLIP-seq
MIRT1399044	hsa-miR-1285	CLIP-seq
MIRT1399045	hsa-miR-1827	CLIP-seq
MIRT1399046	hsa-miR-188-3p	CLIP-seq
MIRT1399047	hsa-miR-188-5p	CLIP-seq
MIRT1399048	hsa-miR-3140-3p	CLIP-seq
MIRT1399049	hsa-miR-3156-3p	CLIP-seq
MIRT1399050	hsa-miR-3187-5p	CLIP-seq
MIRT1399051	hsa-miR-3929	CLIP-seq
MIRT1399052	hsa-miR-425	CLIP-seq
MIRT1399053	hsa-miR-4419b	CLIP-seq
MIRT1399054	hsa-miR-4459	CLIP-seq
MIRT1399055	hsa-miR-4478	CLIP-seq
MIRT1399056	hsa-miR-4505	CLIP-seq
MIRT1399057	hsa-miR-4645-5p	CLIP-seq
MIRT1399058	hsa-miR-4649-3p	CLIP-seq
MIRT1399059	hsa-miR-4673	CLIP-seq
MIRT1399060	hsa-miR-4695-5p	CLIP-seq
MIRT1399061	hsa-miR-4722-5p	CLIP-seq
MIRT1399062	hsa-miR-4768-3p	CLIP-seq
MIRT1399063	hsa-miR-4780	CLIP-seq
MIRT1399064	hsa-miR-4793-3p	CLIP-seq
MIRT1399065	hsa-miR-508-5p	CLIP-seq
MIRT1399066	hsa-miR-603	CLIP-seq
MIRT1399067	hsa-miR-612	CLIP-seq
MIRT1399068	hsa-miR-623	CLIP-seq
MIRT1399069	hsa-miR-642b	CLIP-seq
MIRT1399070	hsa-miR-658	CLIP-seq
MIRT1399071	hsa-miR-665	CLIP-seq
MIRT1399072	hsa-miR-940	CLIP-seq
MIRT1399073	hsa-miR-103a	CLIP-seq
MIRT1399074	hsa-miR-105	CLIP-seq
MIRT1399075	hsa-miR-107	CLIP-seq
MIRT1399076	hsa-miR-1276	CLIP-seq
MIRT1399077	hsa-miR-15a	CLIP-seq
MIRT1399078	hsa-miR-15b	CLIP-seq
MIRT1399079	hsa-miR-16	CLIP-seq
MIRT1399045	hsa-miR-1827	CLIP-seq
MIRT1399047	hsa-miR-188-5p	CLIP-seq
MIRT1399080	hsa-miR-195	CLIP-seq
MIRT1399081	hsa-miR-2053	CLIP-seq
MIRT1399082	hsa-miR-2054	CLIP-seq
MIRT1399083	hsa-miR-3117-5p	CLIP-seq
MIRT1399084	hsa-miR-3143	CLIP-seq
MIRT1399085	hsa-miR-3189-3p	CLIP-seq
MIRT1399086	hsa-miR-3199	CLIP-seq
MIRT1399087	hsa-miR-3646	CLIP-seq
MIRT1399088	hsa-miR-369-3p	CLIP-seq
MIRT1399089	hsa-miR-374a	CLIP-seq
MIRT1399090	hsa-miR-374b	CLIP-seq
MIRT1399091	hsa-miR-375	CLIP-seq
MIRT1399092	hsa-miR-380	CLIP-seq
MIRT1399093	hsa-miR-3942-5p	CLIP-seq
MIRT1399094	hsa-miR-424	CLIP-seq
MIRT1399095	hsa-miR-4265	CLIP-seq
MIRT1399096	hsa-miR-4296	CLIP-seq
MIRT1399097	hsa-miR-4318	CLIP-seq
MIRT1399098	hsa-miR-4322	CLIP-seq
MIRT1399099	hsa-miR-4328	CLIP-seq
MIRT1399100	hsa-miR-4417	CLIP-seq
MIRT1399054	hsa-miR-4459	CLIP-seq
MIRT1399101	hsa-miR-451b	CLIP-seq
MIRT1399102	hsa-miR-4670-3p	CLIP-seq
MIRT1399060	hsa-miR-4695-5p	CLIP-seq
MIRT1399103	hsa-miR-4703-5p	CLIP-seq
MIRT1399104	hsa-miR-4711-5p	CLIP-seq
MIRT1399061	hsa-miR-4722-5p	CLIP-seq
MIRT1399062	hsa-miR-4768-3p	CLIP-seq
MIRT1399105	hsa-miR-4775	CLIP-seq
MIRT1399063	hsa-miR-4780	CLIP-seq
MIRT1399106	hsa-miR-497	CLIP-seq
MIRT1399107	hsa-miR-543	CLIP-seq
MIRT1399108	hsa-miR-569	CLIP-seq
MIRT1399109	hsa-miR-582-3p	CLIP-seq
MIRT1399068	hsa-miR-623	CLIP-seq
MIRT1399070	hsa-miR-658	CLIP-seq
MIRT1399071	hsa-miR-665	CLIP-seq
MIRT1399072	hsa-miR-940	CLIP-seq
MIRT2119630	hsa-miR-1207-5p	CLIP-seq
MIRT1399044	hsa-miR-1285	CLIP-seq
MIRT2119631	hsa-miR-1321	CLIP-seq
MIRT2119632	hsa-miR-204	CLIP-seq
MIRT1399081	hsa-miR-2053	CLIP-seq
MIRT2119633	hsa-miR-211	CLIP-seq
MIRT2119634	hsa-miR-3121-5p	CLIP-seq
MIRT1399050	hsa-miR-3187-5p	CLIP-seq
MIRT1399085	hsa-miR-3189-3p	CLIP-seq
MIRT2119635	hsa-miR-3938	CLIP-seq
MIRT2119636	hsa-miR-3940-3p	CLIP-seq
MIRT2119637	hsa-miR-4270	CLIP-seq
MIRT2119638	hsa-miR-4441	CLIP-seq
MIRT2119639	hsa-miR-4494	CLIP-seq
MIRT2119640	hsa-miR-4739	CLIP-seq
MIRT2119641	hsa-miR-4755-5p	CLIP-seq
MIRT2119642	hsa-miR-4756-5p	CLIP-seq
MIRT2119643	hsa-miR-4763-3p	CLIP-seq
MIRT2119644	hsa-miR-490-3p	CLIP-seq
MIRT1399109	hsa-miR-582-3p	CLIP-seq
MIRT1399067	hsa-miR-612	CLIP-seq
MIRT1399068	hsa-miR-623	CLIP-seq
MIRT2119645	hsa-miR-649	CLIP-seq
MIRT2119630	hsa-miR-1207-5p	CLIP-seq
MIRT1399044	hsa-miR-1285	CLIP-seq
MIRT2341779	hsa-miR-132	CLIP-seq
MIRT2119631	hsa-miR-1321	CLIP-seq
MIRT2341780	hsa-miR-212	CLIP-seq
MIRT1399050	hsa-miR-3187-5p	CLIP-seq
MIRT1399085	hsa-miR-3189-3p	CLIP-seq
MIRT2341781	hsa-miR-329	CLIP-seq
MIRT2341782	hsa-miR-362-3p	CLIP-seq
MIRT2119636	hsa-miR-3940-3p	CLIP-seq
MIRT2341783	hsa-miR-3941	CLIP-seq
MIRT2119637	hsa-miR-4270	CLIP-seq
MIRT2119638	hsa-miR-4441	CLIP-seq
MIRT1399054	hsa-miR-4459	CLIP-seq
MIRT1399058	hsa-miR-4649-3p	CLIP-seq
MIRT2119640	hsa-miR-4739	CLIP-seq
MIRT2119642	hsa-miR-4756-5p	CLIP-seq
MIRT2119643	hsa-miR-4763-3p	CLIP-seq
MIRT1399062	hsa-miR-4768-3p	CLIP-seq
MIRT2341784	hsa-miR-4797-3p	CLIP-seq
MIRT2119644	hsa-miR-490-3p	CLIP-seq
MIRT2341785	hsa-miR-548p	CLIP-seq
MIRT1399109	hsa-miR-582-3p	CLIP-seq
MIRT1399066	hsa-miR-603	CLIP-seq
MIRT1399067	hsa-miR-612	CLIP-seq
MIRT2119645	hsa-miR-649	CLIP-seq
MIRT2119630	hsa-miR-1207-5p	CLIP-seq
MIRT1399044	hsa-miR-1285	CLIP-seq
MIRT2119631	hsa-miR-1321	CLIP-seq
MIRT1399050	hsa-miR-3187-5p	CLIP-seq
MIRT1399085	hsa-miR-3189-3p	CLIP-seq
MIRT2119637	hsa-miR-4270	CLIP-seq
MIRT2119638	hsa-miR-4441	CLIP-seq
MIRT2119640	hsa-miR-4739	CLIP-seq
MIRT2119642	hsa-miR-4756-5p	CLIP-seq
MIRT2119643	hsa-miR-4763-3p	CLIP-seq
MIRT2119644	hsa-miR-490-3p	CLIP-seq
MIRT1399109	hsa-miR-582-3p	CLIP-seq
MIRT1399067	hsa-miR-612	CLIP-seq
MIRT2119645	hsa-miR-649	CLIP-seq
MIRT2460704	hsa-miR-3120-5p	CLIP-seq
MIRT2460705	hsa-miR-3613-3p	CLIP-seq
MIRT2460706	hsa-miR-3664-5p	CLIP-seq
MIRT2460707	hsa-miR-3672	CLIP-seq
MIRT2460708	hsa-miR-371-5p	CLIP-seq
MIRT2460709	hsa-miR-371b-5p	CLIP-seq
MIRT2460710	hsa-miR-4522	CLIP-seq
MIRT2460711	hsa-miR-548a-5p	CLIP-seq
MIRT2460712	hsa-miR-548ab	CLIP-seq
MIRT2460713	hsa-miR-548ak	CLIP-seq
MIRT2460714	hsa-miR-548b-5p	CLIP-seq
MIRT2460715	hsa-miR-548c-5p	CLIP-seq
MIRT2460716	hsa-miR-548d-5p	CLIP-seq
MIRT2460717	hsa-miR-548h	CLIP-seq
MIRT2460718	hsa-miR-548i	CLIP-seq
MIRT2460719	hsa-miR-548j	CLIP-seq
MIRT2460720	hsa-miR-548n	CLIP-seq
MIRT2460721	hsa-miR-548w	CLIP-seq
MIRT2460722	hsa-miR-548y	CLIP-seq
MIRT2460723	hsa-miR-559	CLIP-seq
MIRT2635693	hsa-miR-1273f	CLIP-seq
MIRT1399044	hsa-miR-1285	CLIP-seq
MIRT1399077	hsa-miR-15a	CLIP-seq
MIRT1399078	hsa-miR-15b	CLIP-seq
MIRT1399079	hsa-miR-16	CLIP-seq
MIRT1399080	hsa-miR-195	CLIP-seq
MIRT1399083	hsa-miR-3117-5p	CLIP-seq
MIRT2460704	hsa-miR-3120-5p	CLIP-seq
MIRT1399050	hsa-miR-3187-5p	CLIP-seq
MIRT2460705	hsa-miR-3613-3p	CLIP-seq
MIRT1399087	hsa-miR-3646	CLIP-seq
MIRT2460706	hsa-miR-3664-5p	CLIP-seq
MIRT2460707	hsa-miR-3672	CLIP-seq
MIRT2460708	hsa-miR-371-5p	CLIP-seq
MIRT2460709	hsa-miR-371b-5p	CLIP-seq
MIRT1399094	hsa-miR-424	CLIP-seq
MIRT1399056	hsa-miR-4505	CLIP-seq
MIRT1399101	hsa-miR-451b	CLIP-seq
MIRT2460710	hsa-miR-4522	CLIP-seq
MIRT1399057	hsa-miR-4645-5p	CLIP-seq
MIRT1399059	hsa-miR-4673	CLIP-seq
MIRT2635694	hsa-miR-4747-5p	CLIP-seq
MIRT2635695	hsa-miR-4765	CLIP-seq
MIRT1399064	hsa-miR-4793-3p	CLIP-seq
MIRT2341784	hsa-miR-4797-3p	CLIP-seq
MIRT2635696	hsa-miR-4797-5p	CLIP-seq
MIRT1399106	hsa-miR-497	CLIP-seq
MIRT1399065	hsa-miR-508-5p	CLIP-seq
MIRT2635697	hsa-miR-520a-5p	CLIP-seq
MIRT2635698	hsa-miR-525-5p	CLIP-seq
MIRT2460711	hsa-miR-548a-5p	CLIP-seq
MIRT2460712	hsa-miR-548ab	CLIP-seq
MIRT2460713	hsa-miR-548ak	CLIP-seq
MIRT2460714	hsa-miR-548b-5p	CLIP-seq
MIRT2460715	hsa-miR-548c-5p	CLIP-seq
MIRT2460716	hsa-miR-548d-5p	CLIP-seq
MIRT2460717	hsa-miR-548h	CLIP-seq
MIRT2460718	hsa-miR-548i	CLIP-seq
MIRT2460719	hsa-miR-548j	CLIP-seq
MIRT2460720	hsa-miR-548n	CLIP-seq
MIRT2341785	hsa-miR-548p	CLIP-seq
MIRT2460721	hsa-miR-548w	CLIP-seq
MIRT2460722	hsa-miR-548y	CLIP-seq
MIRT2460723	hsa-miR-559	CLIP-seq
MIRT1399066	hsa-miR-603	CLIP-seq
MIRT1399067	hsa-miR-612	CLIP-seq
MIRT1399069	hsa-miR-642b	CLIP-seq
MIRT2635699	hsa-miR-759	CLIP-seq
MIRT1399044	hsa-miR-1285	CLIP-seq
MIRT2692306	hsa-miR-1304	CLIP-seq
MIRT2119634	hsa-miR-3121-5p	CLIP-seq
MIRT2692307	hsa-miR-3184	CLIP-seq
MIRT1399050	hsa-miR-3187-5p	CLIP-seq
MIRT2692308	hsa-miR-3611	CLIP-seq
MIRT2692309	hsa-miR-3923	CLIP-seq
MIRT2692310	hsa-miR-423-5p	CLIP-seq
MIRT2692311	hsa-miR-4427	CLIP-seq
MIRT1399056	hsa-miR-4505	CLIP-seq
MIRT1399057	hsa-miR-4645-5p	CLIP-seq
MIRT1399059	hsa-miR-4673	CLIP-seq
MIRT2692312	hsa-miR-4688	CLIP-seq
MIRT2692313	hsa-miR-4714-3p	CLIP-seq
MIRT1399064	hsa-miR-4793-3p	CLIP-seq
MIRT2635696	hsa-miR-4797-5p	CLIP-seq
MIRT1399065	hsa-miR-508-5p	CLIP-seq
MIRT1399066	hsa-miR-603	CLIP-seq
MIRT1399067	hsa-miR-612	CLIP-seq
MIRT2692314	hsa-miR-628-5p	CLIP-seq
MIRT2119645	hsa-miR-649	CLIP-seq
MIRT2635699	hsa-miR-759	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005737	Component	Cytoplasm	IEA
GO:0005905	Component	Clathrin-coated pit	IEA
GO:0006897	Process	Endocytosis	IEA
GO:0006897	Process	Endocytosis	IEA
GO:0006929	Process	Substrate-dependent cell migration	IEA
GO:0008021	Component	Synaptic vesicle	IBA
GO:0016020	Component	Membrane	IEA
GO:0030100	Process	Regulation of endocytosis	IBA
GO:0030100	Process	Regulation of endocytosis	IDA	11454741
GO:0030100	Process	Regulation of endocytosis	IEA
GO:0030122	Component	AP-2 adaptor complex	IBA
GO:0031252	Component	Cell leading edge	IEA
GO:0035615	Function	Clathrin adaptor activity	IBA
GO:0042995	Component	Cell projection	IEA
GO:0048008	Process	Platelet-derived growth factor receptor signaling pathway	IEA
GO:0048041	Process	Focal adhesion assembly	IEA
GO:0048488	Process	Synaptic vesicle endocytosis	IBA
GO:0072583	Process	Clathrin-dependent endocytosis	IBA
GO:0097178	Process	Ruffle assembly	IEA
GO:0120181	Process	Focal adhesion disassembly	IEA
GO:0140312	Function	Cargo adaptor activity	IEA

Other IDs

• MIM: 605357
• HGNC: 17003
• e!Ensembl: ENSG00000243244

Interactions View interactions

Pathways

Reactome:

Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Myoepithelial tumor	Uncertain significance	rs758514131	RCV002463969

Associations from Text Mining
Disease Name	Relationship Type	References
Carcinoma Renal Cell	Inhibit	36759775
Macular Degeneration	Associate	28775256
Neoplasm Metastasis	Inhibit	36759775
Neoplasms	Associate	36759775
Polycystic Ovary Syndrome	Stimulate	26305227