DSTN (destrin, actin depolymerizing factor)

Gene

• Entrez ID: 11034
• Gene name: Destrin, actin depolymerizing factor
• Gene symbol: DSTN
• Synonyms (NCBI Gene): ACTDP, ADF, HEL32, bA462D18.2
• Chromosome: 20
• Chromosome location: 20p12.1
• Summary: The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) an

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT041745	hsa-miR-484	CLASH	23622248
MIRT507530	hsa-miR-5571-5p	PAR-CLIP	21572407
MIRT507529	hsa-miR-942-3p	PAR-CLIP	21572407
MIRT545615	hsa-miR-4728-3p	PAR-CLIP	21572407
MIRT329006	hsa-miR-380-3p	PAR-CLIP	21572407
MIRT507528	hsa-miR-4717-3p	PAR-CLIP	21572407
MIRT507527	hsa-miR-6515-3p	PAR-CLIP	21572407
MIRT507526	hsa-miR-1236-3p	PAR-CLIP	21572407
MIRT329015	hsa-miR-7162-3p	PAR-CLIP	21572407
MIRT507525	hsa-miR-412-3p	PAR-CLIP	21572407
MIRT507523	hsa-miR-6754-3p	PAR-CLIP	21572407
MIRT507524	hsa-miR-6837-3p	PAR-CLIP	21572407
MIRT329008	hsa-miR-655-5p	PAR-CLIP	21572407
MIRT545614	hsa-miR-377-5p	PAR-CLIP	21572407
MIRT545613	hsa-miR-6086	PAR-CLIP	21572407
MIRT545612	hsa-miR-4663	PAR-CLIP	21572407
MIRT545611	hsa-miR-7160-5p	PAR-CLIP	21572407
MIRT545610	hsa-miR-8077	PAR-CLIP	21572407
MIRT507521	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT507520	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT507519	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT507518	hsa-miR-23c	PAR-CLIP	21572407
MIRT507517	hsa-miR-4753-3p	PAR-CLIP	21572407
MIRT329009	hsa-miR-2054	PAR-CLIP	21572407
MIRT507516	hsa-miR-6809-3p	PAR-CLIP	21572407
MIRT507532	hsa-miR-4676-3p	PAR-CLIP	23446348
MIRT507533	hsa-miR-892c-3p	PAR-CLIP	23446348
MIRT507531	hsa-miR-452-5p	PAR-CLIP	23446348
MIRT507530	hsa-miR-5571-5p	PAR-CLIP	23446348
MIRT507529	hsa-miR-942-3p	PAR-CLIP	23446348
MIRT507528	hsa-miR-4717-3p	PAR-CLIP	23446348
MIRT507527	hsa-miR-6515-3p	PAR-CLIP	23446348
MIRT507526	hsa-miR-1236-3p	PAR-CLIP	23446348
MIRT507525	hsa-miR-412-3p	PAR-CLIP	23446348
MIRT507523	hsa-miR-6754-3p	PAR-CLIP	23446348
MIRT507524	hsa-miR-6837-3p	PAR-CLIP	23446348
MIRT507522	hsa-miR-4693-5p	PAR-CLIP	23446348
MIRT507521	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT507520	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT507519	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT507518	hsa-miR-23c	PAR-CLIP	23446348
MIRT507517	hsa-miR-4753-3p	PAR-CLIP	23446348
MIRT507516	hsa-miR-6809-3p	PAR-CLIP	23446348
MIRT507532	hsa-miR-4676-3p	PAR-CLIP	23446348
MIRT507533	hsa-miR-892c-3p	PAR-CLIP	23446348
MIRT507531	hsa-miR-452-5p	PAR-CLIP	23446348
MIRT507530	hsa-miR-5571-5p	PAR-CLIP	23446348
MIRT507529	hsa-miR-942-3p	PAR-CLIP	23446348
MIRT507528	hsa-miR-4717-3p	PAR-CLIP	23446348
MIRT507527	hsa-miR-6515-3p	PAR-CLIP	23446348
MIRT507526	hsa-miR-1236-3p	PAR-CLIP	23446348
MIRT507525	hsa-miR-412-3p	PAR-CLIP	23446348
MIRT507523	hsa-miR-6754-3p	PAR-CLIP	23446348
MIRT507524	hsa-miR-6837-3p	PAR-CLIP	23446348
MIRT507522	hsa-miR-4693-5p	PAR-CLIP	23446348
MIRT507521	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT507520	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT507519	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT507518	hsa-miR-23c	PAR-CLIP	23446348
MIRT507517	hsa-miR-4753-3p	PAR-CLIP	23446348
MIRT507516	hsa-miR-6809-3p	PAR-CLIP	23446348
MIRT733526	hsa-miR-362-5p	Western blotting, Microarray, RNA-seq	34120636
MIRT507530	hsa-miR-5571-5p	PAR-CLIP	21572407
MIRT507529	hsa-miR-942-3p	PAR-CLIP	21572407
MIRT545615	hsa-miR-4728-3p	PAR-CLIP	21572407
MIRT329006	hsa-miR-380-3p	PAR-CLIP	21572407
MIRT507528	hsa-miR-4717-3p	PAR-CLIP	21572407
MIRT507527	hsa-miR-6515-3p	PAR-CLIP	21572407
MIRT507526	hsa-miR-1236-3p	PAR-CLIP	21572407
MIRT329015	hsa-miR-7162-3p	PAR-CLIP	21572407
MIRT507525	hsa-miR-412-3p	PAR-CLIP	21572407
MIRT507523	hsa-miR-6754-3p	PAR-CLIP	21572407
MIRT507524	hsa-miR-6837-3p	PAR-CLIP	21572407
MIRT329008	hsa-miR-655-5p	PAR-CLIP	21572407
MIRT545614	hsa-miR-377-5p	PAR-CLIP	21572407
MIRT545613	hsa-miR-6086	PAR-CLIP	21572407
MIRT545612	hsa-miR-4663	PAR-CLIP	21572407
MIRT545611	hsa-miR-7160-5p	PAR-CLIP	21572407
MIRT545610	hsa-miR-8077	PAR-CLIP	21572407
MIRT507521	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT507520	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT507519	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT507518	hsa-miR-23c	PAR-CLIP	21572407
MIRT507517	hsa-miR-4753-3p	PAR-CLIP	21572407
MIRT329009	hsa-miR-2054	PAR-CLIP	21572407
MIRT507516	hsa-miR-6809-3p	PAR-CLIP	21572407
MIRT507532	hsa-miR-4676-3p	PAR-CLIP	23446348
MIRT507533	hsa-miR-892c-3p	PAR-CLIP	23446348
MIRT507531	hsa-miR-452-5p	PAR-CLIP	23446348
MIRT507530	hsa-miR-5571-5p	PAR-CLIP	23446348
MIRT507529	hsa-miR-942-3p	PAR-CLIP	23446348
MIRT507528	hsa-miR-4717-3p	PAR-CLIP	23446348
MIRT507527	hsa-miR-6515-3p	PAR-CLIP	23446348
MIRT507526	hsa-miR-1236-3p	PAR-CLIP	23446348
MIRT507525	hsa-miR-412-3p	PAR-CLIP	23446348
MIRT507523	hsa-miR-6754-3p	PAR-CLIP	23446348
MIRT507524	hsa-miR-6837-3p	PAR-CLIP	23446348
MIRT507522	hsa-miR-4693-5p	PAR-CLIP	23446348
MIRT507521	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT507520	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT507519	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT507518	hsa-miR-23c	PAR-CLIP	23446348
MIRT507517	hsa-miR-4753-3p	PAR-CLIP	23446348
MIRT507516	hsa-miR-6809-3p	PAR-CLIP	23446348
MIRT507532	hsa-miR-4676-3p	PAR-CLIP	23446348
MIRT507533	hsa-miR-892c-3p	PAR-CLIP	23446348
MIRT507531	hsa-miR-452-5p	PAR-CLIP	23446348
MIRT507530	hsa-miR-5571-5p	PAR-CLIP	23446348
MIRT507529	hsa-miR-942-3p	PAR-CLIP	23446348
MIRT507528	hsa-miR-4717-3p	PAR-CLIP	23446348
MIRT507527	hsa-miR-6515-3p	PAR-CLIP	23446348
MIRT507526	hsa-miR-1236-3p	PAR-CLIP	23446348
MIRT507525	hsa-miR-412-3p	PAR-CLIP	23446348
MIRT507523	hsa-miR-6754-3p	PAR-CLIP	23446348
MIRT507524	hsa-miR-6837-3p	PAR-CLIP	23446348
MIRT507522	hsa-miR-4693-5p	PAR-CLIP	23446348
MIRT507521	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT507520	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT507519	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT507518	hsa-miR-23c	PAR-CLIP	23446348
MIRT507517	hsa-miR-4753-3p	PAR-CLIP	23446348
MIRT507516	hsa-miR-6809-3p	PAR-CLIP	23446348
MIRT946298	hsa-miR-129-3p	CLIP-seq
MIRT946299	hsa-miR-23a	CLIP-seq
MIRT946300	hsa-miR-23b	CLIP-seq
MIRT946301	hsa-miR-330-3p	CLIP-seq
MIRT946302	hsa-miR-33a	CLIP-seq
MIRT946303	hsa-miR-33b	CLIP-seq
MIRT946304	hsa-miR-4276	CLIP-seq
MIRT946305	hsa-miR-4687-5p	CLIP-seq
MIRT946306	hsa-miR-4725-5p	CLIP-seq
MIRT946307	hsa-miR-4735-5p	CLIP-seq
MIRT946308	hsa-miR-4775	CLIP-seq
MIRT946309	hsa-miR-4786-5p	CLIP-seq
MIRT946310	hsa-miR-495	CLIP-seq
MIRT946311	hsa-miR-504	CLIP-seq
MIRT946312	hsa-miR-548a-3p	CLIP-seq
MIRT946313	hsa-miR-548e	CLIP-seq
MIRT946314	hsa-miR-548f	CLIP-seq
MIRT946315	hsa-miR-769-5p	CLIP-seq
MIRT946298	hsa-miR-129-3p	CLIP-seq
MIRT946316	hsa-miR-1323	CLIP-seq
MIRT946317	hsa-miR-3187-3p	CLIP-seq
MIRT946301	hsa-miR-330-3p	CLIP-seq
MIRT946318	hsa-miR-3591-5p	CLIP-seq
MIRT946319	hsa-miR-3617	CLIP-seq
MIRT946320	hsa-miR-3926	CLIP-seq
MIRT946321	hsa-miR-4255	CLIP-seq
MIRT946322	hsa-miR-4435	CLIP-seq
MIRT946323	hsa-miR-4652-3p	CLIP-seq
MIRT946305	hsa-miR-4687-5p	CLIP-seq
MIRT946324	hsa-miR-4701-5p	CLIP-seq
MIRT946307	hsa-miR-4735-5p	CLIP-seq
MIRT946325	hsa-miR-4742-3p	CLIP-seq
MIRT946308	hsa-miR-4775	CLIP-seq
MIRT946326	hsa-miR-4778-5p	CLIP-seq
MIRT946327	hsa-miR-486-5p	CLIP-seq
MIRT946310	hsa-miR-495	CLIP-seq
MIRT946328	hsa-miR-548o	CLIP-seq
MIRT946329	hsa-miR-548s	CLIP-seq
MIRT946330	hsa-miR-588	CLIP-seq
MIRT946331	hsa-miR-630	CLIP-seq
MIRT946332	hsa-miR-641	CLIP-seq
MIRT946333	hsa-miR-656	CLIP-seq
MIRT1548060	hsa-miR-550b	CLIP-seq
MIRT946318	hsa-miR-3591-5p	CLIP-seq
MIRT1548061	hsa-miR-4280	CLIP-seq
MIRT1548060	hsa-miR-550b	CLIP-seq
MIRT1556246	hsa-miR-1185	CLIP-seq
MIRT1556247	hsa-miR-3143	CLIP-seq
MIRT1556248	hsa-miR-3679-5p	CLIP-seq
MIRT1556249	hsa-miR-451b	CLIP-seq
MIRT1556250	hsa-miR-543	CLIP-seq
MIRT1980224	hsa-miR-1207-5p	CLIP-seq
MIRT1980225	hsa-miR-1236	CLIP-seq
MIRT946316	hsa-miR-1323	CLIP-seq
MIRT1980226	hsa-miR-1909	CLIP-seq
MIRT1980227	hsa-miR-1976	CLIP-seq
MIRT946299	hsa-miR-23a	CLIP-seq
MIRT946300	hsa-miR-23b	CLIP-seq
MIRT1980228	hsa-miR-3140-5p	CLIP-seq
MIRT1980229	hsa-miR-3176	CLIP-seq
MIRT946317	hsa-miR-3187-3p	CLIP-seq
MIRT1980230	hsa-miR-3665	CLIP-seq
MIRT1980231	hsa-miR-3670	CLIP-seq
MIRT1980232	hsa-miR-380	CLIP-seq
MIRT1980233	hsa-miR-3922-3p	CLIP-seq
MIRT946320	hsa-miR-3926	CLIP-seq
MIRT1980234	hsa-miR-412	CLIP-seq
MIRT946304	hsa-miR-4276	CLIP-seq
MIRT1980235	hsa-miR-4279	CLIP-seq
MIRT946322	hsa-miR-4435	CLIP-seq
MIRT946324	hsa-miR-4701-5p	CLIP-seq
MIRT946306	hsa-miR-4725-5p	CLIP-seq
MIRT1980236	hsa-miR-4736	CLIP-seq
MIRT1980237	hsa-miR-4763-3p	CLIP-seq
MIRT946309	hsa-miR-4786-5p	CLIP-seq
MIRT946311	hsa-miR-504	CLIP-seq
MIRT946328	hsa-miR-548o	CLIP-seq
MIRT946329	hsa-miR-548s	CLIP-seq
MIRT946330	hsa-miR-588	CLIP-seq
MIRT1980238	hsa-miR-764	CLIP-seq
MIRT946315	hsa-miR-769-5p	CLIP-seq
MIRT1980239	hsa-miR-885-5p	CLIP-seq
MIRT2215313	hsa-miR-1200	CLIP-seq
MIRT1980225	hsa-miR-1236	CLIP-seq
MIRT2215314	hsa-miR-1257	CLIP-seq
MIRT946298	hsa-miR-129-3p	CLIP-seq
MIRT2215315	hsa-miR-1304	CLIP-seq
MIRT2215316	hsa-miR-136	CLIP-seq
MIRT2215317	hsa-miR-140-3p	CLIP-seq
MIRT2215318	hsa-miR-151-3p	CLIP-seq
MIRT2215319	hsa-miR-1827	CLIP-seq
MIRT1980227	hsa-miR-1976	CLIP-seq
MIRT946299	hsa-miR-23a	CLIP-seq
MIRT946300	hsa-miR-23b	CLIP-seq
MIRT2215320	hsa-miR-299-3p	CLIP-seq
MIRT2215321	hsa-miR-3138	CLIP-seq
MIRT1980228	hsa-miR-3140-5p	CLIP-seq
MIRT946301	hsa-miR-330-3p	CLIP-seq
MIRT946302	hsa-miR-33a	CLIP-seq
MIRT946303	hsa-miR-33b	CLIP-seq
MIRT2215322	hsa-miR-340	CLIP-seq
MIRT946318	hsa-miR-3591-5p	CLIP-seq
MIRT1980231	hsa-miR-3670	CLIP-seq
MIRT2215323	hsa-miR-3685	CLIP-seq
MIRT2215324	hsa-miR-374a	CLIP-seq
MIRT2215325	hsa-miR-374b	CLIP-seq
MIRT1980232	hsa-miR-380	CLIP-seq
MIRT2215326	hsa-miR-384	CLIP-seq
MIRT2215327	hsa-miR-3934	CLIP-seq
MIRT2215328	hsa-miR-3941	CLIP-seq
MIRT2215329	hsa-miR-3973	CLIP-seq
MIRT1980234	hsa-miR-412	CLIP-seq
MIRT946321	hsa-miR-4255	CLIP-seq
MIRT946304	hsa-miR-4276	CLIP-seq
MIRT1980235	hsa-miR-4279	CLIP-seq
MIRT1548061	hsa-miR-4280	CLIP-seq
MIRT2215330	hsa-miR-4324	CLIP-seq
MIRT2215331	hsa-miR-4453	CLIP-seq
MIRT2215332	hsa-miR-4491	CLIP-seq
MIRT2215333	hsa-miR-450b-5p	CLIP-seq
MIRT2215334	hsa-miR-452	CLIP-seq
MIRT2215335	hsa-miR-4528	CLIP-seq
MIRT2215336	hsa-miR-4538	CLIP-seq
MIRT2215337	hsa-miR-455-5p	CLIP-seq
MIRT2215338	hsa-miR-4639-3p	CLIP-seq
MIRT2215339	hsa-miR-4643	CLIP-seq
MIRT2215340	hsa-miR-4657	CLIP-seq
MIRT2215341	hsa-miR-466	CLIP-seq
MIRT2215342	hsa-miR-4666-3p	CLIP-seq
MIRT2215343	hsa-miR-4668-3p	CLIP-seq
MIRT2215344	hsa-miR-4672	CLIP-seq
MIRT946305	hsa-miR-4687-5p	CLIP-seq
MIRT2215345	hsa-miR-4696	CLIP-seq
MIRT946307	hsa-miR-4735-5p	CLIP-seq
MIRT946325	hsa-miR-4742-3p	CLIP-seq
MIRT2215346	hsa-miR-4755-3p	CLIP-seq
MIRT2215347	hsa-miR-4760-5p	CLIP-seq
MIRT2215348	hsa-miR-4789-3p	CLIP-seq
MIRT2215349	hsa-miR-4790-3p	CLIP-seq
MIRT2215350	hsa-miR-4800-5p	CLIP-seq
MIRT2215351	hsa-miR-4804-3p	CLIP-seq
MIRT946327	hsa-miR-486-5p	CLIP-seq
MIRT946310	hsa-miR-495	CLIP-seq
MIRT2215352	hsa-miR-544b	CLIP-seq
MIRT946312	hsa-miR-548a-3p	CLIP-seq
MIRT2215353	hsa-miR-548a-5p	CLIP-seq
MIRT2215354	hsa-miR-548ab	CLIP-seq
MIRT2215355	hsa-miR-548ak	CLIP-seq
MIRT2215356	hsa-miR-548b-5p	CLIP-seq
MIRT2215357	hsa-miR-548c-3p	CLIP-seq
MIRT2215358	hsa-miR-548c-5p	CLIP-seq
MIRT2215359	hsa-miR-548d-5p	CLIP-seq
MIRT946313	hsa-miR-548e	CLIP-seq
MIRT946314	hsa-miR-548f	CLIP-seq
MIRT2215360	hsa-miR-548h	CLIP-seq
MIRT2215361	hsa-miR-548i	CLIP-seq
MIRT2215362	hsa-miR-548j	CLIP-seq
MIRT2215363	hsa-miR-548p	CLIP-seq
MIRT2215364	hsa-miR-548w	CLIP-seq
MIRT2215365	hsa-miR-548y	CLIP-seq
MIRT2215366	hsa-miR-550a	CLIP-seq
MIRT1548060	hsa-miR-550b	CLIP-seq
MIRT2215367	hsa-miR-552	CLIP-seq
MIRT2215368	hsa-miR-559	CLIP-seq
MIRT946331	hsa-miR-630	CLIP-seq
MIRT946333	hsa-miR-656	CLIP-seq
MIRT2215369	hsa-miR-668	CLIP-seq
MIRT2215370	hsa-miR-676	CLIP-seq
MIRT1980239	hsa-miR-885-5p	CLIP-seq
MIRT946309	hsa-miR-4786-5p	CLIP-seq
MIRT946315	hsa-miR-769-5p	CLIP-seq
MIRT1980224	hsa-miR-1207-5p	CLIP-seq
MIRT1980226	hsa-miR-1909	CLIP-seq
MIRT1980230	hsa-miR-3665	CLIP-seq
MIRT1980236	hsa-miR-4736	CLIP-seq
MIRT946325	hsa-miR-4742-3p	CLIP-seq
MIRT1980237	hsa-miR-4763-3p	CLIP-seq
MIRT946327	hsa-miR-486-5p	CLIP-seq
MIRT946331	hsa-miR-630	CLIP-seq
MIRT1980238	hsa-miR-764	CLIP-seq
MIRT1556246	hsa-miR-1185	CLIP-seq
MIRT1980224	hsa-miR-1207-5p	CLIP-seq
MIRT1980225	hsa-miR-1236	CLIP-seq
MIRT2215314	hsa-miR-1257	CLIP-seq
MIRT2215315	hsa-miR-1304	CLIP-seq
MIRT2215316	hsa-miR-136	CLIP-seq
MIRT2215319	hsa-miR-1827	CLIP-seq
MIRT2519772	hsa-miR-186	CLIP-seq
MIRT1980226	hsa-miR-1909	CLIP-seq
MIRT2519773	hsa-miR-3133	CLIP-seq
MIRT1556247	hsa-miR-3143	CLIP-seq
MIRT1980229	hsa-miR-3176	CLIP-seq
MIRT2519774	hsa-miR-3529	CLIP-seq
MIRT946318	hsa-miR-3591-5p	CLIP-seq
MIRT946319	hsa-miR-3617	CLIP-seq
MIRT2519775	hsa-miR-3619-3p	CLIP-seq
MIRT1980230	hsa-miR-3665	CLIP-seq
MIRT1980231	hsa-miR-3670	CLIP-seq
MIRT1556248	hsa-miR-3679-5p	CLIP-seq
MIRT2519776	hsa-miR-3688-5p	CLIP-seq
MIRT2519777	hsa-miR-379	CLIP-seq
MIRT1980233	hsa-miR-3922-3p	CLIP-seq
MIRT2215328	hsa-miR-3941	CLIP-seq
MIRT946321	hsa-miR-4255	CLIP-seq
MIRT946304	hsa-miR-4276	CLIP-seq
MIRT1548061	hsa-miR-4280	CLIP-seq
MIRT2519778	hsa-miR-4451	CLIP-seq
MIRT2519779	hsa-miR-4474-3p	CLIP-seq
MIRT2215333	hsa-miR-450b-5p	CLIP-seq
MIRT1556249	hsa-miR-451b	CLIP-seq
MIRT2519780	hsa-miR-4520b-3p	CLIP-seq
MIRT2519781	hsa-miR-4529-3p	CLIP-seq
MIRT2519782	hsa-miR-4535	CLIP-seq
MIRT2215337	hsa-miR-455-5p	CLIP-seq
MIRT2215338	hsa-miR-4639-3p	CLIP-seq
MIRT2215339	hsa-miR-4643	CLIP-seq
MIRT2519783	hsa-miR-4650-3p	CLIP-seq
MIRT2215341	hsa-miR-466	CLIP-seq
MIRT2215344	hsa-miR-4672	CLIP-seq
MIRT2215345	hsa-miR-4696	CLIP-seq
MIRT946306	hsa-miR-4725-5p	CLIP-seq
MIRT1980236	hsa-miR-4736	CLIP-seq
MIRT946325	hsa-miR-4742-3p	CLIP-seq
MIRT2215346	hsa-miR-4755-3p	CLIP-seq
MIRT1980237	hsa-miR-4763-3p	CLIP-seq
MIRT2519784	hsa-miR-4776-5p	CLIP-seq
MIRT946326	hsa-miR-4778-5p	CLIP-seq
MIRT946309	hsa-miR-4786-5p	CLIP-seq
MIRT2215348	hsa-miR-4789-3p	CLIP-seq
MIRT2215349	hsa-miR-4790-3p	CLIP-seq
MIRT2519785	hsa-miR-4802-3p	CLIP-seq
MIRT946327	hsa-miR-486-5p	CLIP-seq
MIRT946311	hsa-miR-504	CLIP-seq
MIRT1556250	hsa-miR-543	CLIP-seq
MIRT2215366	hsa-miR-550a	CLIP-seq
MIRT1548060	hsa-miR-550b	CLIP-seq
MIRT946331	hsa-miR-630	CLIP-seq
MIRT946332	hsa-miR-641	CLIP-seq
MIRT946333	hsa-miR-656	CLIP-seq
MIRT2215369	hsa-miR-668	CLIP-seq
MIRT2519786	hsa-miR-671-5p	CLIP-seq
MIRT1980238	hsa-miR-764	CLIP-seq
MIRT946315	hsa-miR-769-5p	CLIP-seq
MIRT1980239	hsa-miR-885-5p	CLIP-seq
MIRT1556246	hsa-miR-1185	CLIP-seq
MIRT1980224	hsa-miR-1207-5p	CLIP-seq
MIRT1980225	hsa-miR-1236	CLIP-seq
MIRT2215315	hsa-miR-1304	CLIP-seq
MIRT2215316	hsa-miR-136	CLIP-seq
MIRT2215319	hsa-miR-1827	CLIP-seq
MIRT2519772	hsa-miR-186	CLIP-seq
MIRT1980226	hsa-miR-1909	CLIP-seq
MIRT2215320	hsa-miR-299-3p	CLIP-seq
MIRT2519773	hsa-miR-3133	CLIP-seq
MIRT2215321	hsa-miR-3138	CLIP-seq
MIRT1556247	hsa-miR-3143	CLIP-seq
MIRT1980229	hsa-miR-3176	CLIP-seq
MIRT2519774	hsa-miR-3529	CLIP-seq
MIRT946318	hsa-miR-3591-5p	CLIP-seq
MIRT946319	hsa-miR-3617	CLIP-seq
MIRT2519775	hsa-miR-3619-3p	CLIP-seq
MIRT1980230	hsa-miR-3665	CLIP-seq
MIRT1556248	hsa-miR-3679-5p	CLIP-seq
MIRT2519776	hsa-miR-3688-5p	CLIP-seq
MIRT2519777	hsa-miR-379	CLIP-seq
MIRT1980232	hsa-miR-380	CLIP-seq
MIRT1980233	hsa-miR-3922-3p	CLIP-seq
MIRT2215328	hsa-miR-3941	CLIP-seq
MIRT946321	hsa-miR-4255	CLIP-seq
MIRT946304	hsa-miR-4276	CLIP-seq
MIRT1548061	hsa-miR-4280	CLIP-seq
MIRT2519778	hsa-miR-4451	CLIP-seq
MIRT2519779	hsa-miR-4474-3p	CLIP-seq
MIRT2215332	hsa-miR-4491	CLIP-seq
MIRT2215333	hsa-miR-450b-5p	CLIP-seq
MIRT1556249	hsa-miR-451b	CLIP-seq
MIRT2519780	hsa-miR-4520b-3p	CLIP-seq
MIRT2519781	hsa-miR-4529-3p	CLIP-seq
MIRT2519782	hsa-miR-4535	CLIP-seq
MIRT2215337	hsa-miR-455-5p	CLIP-seq
MIRT2215339	hsa-miR-4643	CLIP-seq
MIRT2519783	hsa-miR-4650-3p	CLIP-seq
MIRT2215340	hsa-miR-4657	CLIP-seq
MIRT2215341	hsa-miR-466	CLIP-seq
MIRT2215344	hsa-miR-4672	CLIP-seq
MIRT2215345	hsa-miR-4696	CLIP-seq
MIRT946306	hsa-miR-4725-5p	CLIP-seq
MIRT1980236	hsa-miR-4736	CLIP-seq
MIRT946325	hsa-miR-4742-3p	CLIP-seq
MIRT1980237	hsa-miR-4763-3p	CLIP-seq
MIRT2519784	hsa-miR-4776-5p	CLIP-seq
MIRT946326	hsa-miR-4778-5p	CLIP-seq
MIRT946309	hsa-miR-4786-5p	CLIP-seq
MIRT2215348	hsa-miR-4789-3p	CLIP-seq
MIRT2215350	hsa-miR-4800-5p	CLIP-seq
MIRT2519785	hsa-miR-4802-3p	CLIP-seq
MIRT946327	hsa-miR-486-5p	CLIP-seq
MIRT946311	hsa-miR-504	CLIP-seq
MIRT1556250	hsa-miR-543	CLIP-seq
MIRT2215366	hsa-miR-550a	CLIP-seq
MIRT1548060	hsa-miR-550b	CLIP-seq
MIRT946331	hsa-miR-630	CLIP-seq
MIRT946332	hsa-miR-641	CLIP-seq
MIRT946333	hsa-miR-656	CLIP-seq
MIRT2519786	hsa-miR-671-5p	CLIP-seq
MIRT1980238	hsa-miR-764	CLIP-seq
MIRT946315	hsa-miR-769-5p	CLIP-seq
MIRT1980239	hsa-miR-885-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	16189514, 25416956, 29892012, 31515488, 32296183
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0008154	Process	Actin polymerization or depolymerization	TAS	8399167
GO:0015629	Component	Actin cytoskeleton	IBA	21873635
GO:0030042	Process	Actin filament depolymerization	IBA	21873635
GO:0030042	Process	Actin filament depolymerization	IDA	11812157
GO:0030043	Process	Actin filament fragmentation	IBA	21873635
GO:0030836	Process	Positive regulation of actin filament depolymerization	IEA
GO:0030864	Component	Cortical actin cytoskeleton	IEA
GO:0048870	Process	Cell motility	IBA	21873635
GO:0051014	Process	Actin filament severing	IBA	21873635
GO:0051015	Function	Actin filament binding	IBA	21873635
GO:0051015	Function	Actin filament binding	IDA	8399167, 11812157
GO:0070062	Component	Extracellular exosome	HDA	19056867

Other IDs

• MIM: 609114
• HGNC: 15750
• e!Ensembl: ENSG00000125868

Protein

• UniProt ID: P60981
• Protein name: Destrin (Actin-depolymerizing factor) (ADF)
• Protein function: Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00241	Cofilin_ADF	23 → 151	Cofilin/tropomyosin-type actin-binding protein	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely distributed in various tissues.
• Sequence:

  MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDV
  GVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASS
  KDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV

• Sequence length: 165

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Colorectal cancer	Colorectal Carcinoma	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800, rs63750198, rs63751109, rs863223312, rs63750710, rs63751615, rs63750206, rs63750781, rs63750899, rs63750691, rs63750217, rs121912965, rs63749939, rs63751194, rs63750693, rs63750540, rs63751221, rs193922370, rs80359596, rs397514632, rs483352909, rs200495564, rs397514684, rs397516436, rs398122386, rs79512956, rs74953290, rs587779001, rs63750677, rs63749837, rs267607816, rs63751715, rs267607819, rs267607815, rs267607822, rs63749906, rs587778883, rs63750472, rs63751012, rs63750715, rs63750580, rs267607706, rs267607709, rs267607710, rs587778894, rs63750749, rs63750483, rs63751015, rs63751153, rs63751094, rs63751118, rs63750316, rs63749981, rs587778906, rs267607821, rs587778908, rs63750020, rs587778909, rs63750713, rs267607825, rs63751592, rs281864936, rs587778913, rs587778914, rs63749795, rs63750855, rs63749916, rs63749923, rs63751472, rs63751689, rs267607832, rs267607837, rs267607836, rs587778923, rs63750028, rs587778928, rs587778929, rs587778930, rs63751277, rs587778933, rs267607842, rs267607843, rs63750192, rs587778934, rs63750193, rs587778937, rs587778938, rs267607845, rs63751244, rs63751393, rs63751460, rs267607849, rs267607853, rs267607856, rs267607850, rs63751657, rs267607854, rs267607852, rs587778942, rs63750309, rs63750587, rs63749863, rs63751486, rs63750016, rs63749868, rs63750375, rs63750035, rs63750604, rs63750386, rs63750150, rs63750486, rs63751428, rs267607866, rs63749986, rs63751594, rs63750152, rs63750850, rs267607867, rs267607868, rs63751632, rs267607871, rs63751892, rs587778956, rs63750469, rs587778958, rs63749792, rs267607875, rs63751255, rs281864938, rs63751202, rs63750726, rs63751310, rs63749900, rs587778964, rs267607879, rs267607878, rs587778966, rs267607883, rs267607887, rs63750061, rs63750663, rs587778968, rs587778971, rs63750809, rs63749867, rs63750864, rs587778972, rs63751275, rs267607718, rs267607722, rs63750769, rs267607717, rs587778973, rs267607716, rs267607720, rs63749995, rs63750859, rs587778975, rs63750114, rs587778976, rs63750603, rs267607889, rs267607723, rs63750561, rs63750499, rs63751642, rs63751022, rs587778981, rs63750971, rs267607898, rs267607906, rs267607903, rs587778989, rs587778992, rs267607894, rs267607901, rs267607892, rs63750437, rs587778997, rs587778998, rs63750005, rs63750641, rs63751421, rs11541859, rs63750266, rs111052004, rs267607726, rs267607727, rs63750453, rs267607734, rs267607735, rs63751665, rs267607736, rs267607732, rs63749816, rs63750539, rs267607739, rs587779006, rs587779008, rs267607745, rs267607742, rs63751595, rs267607743, rs587779010, rs587779012, rs63750057, rs63749818, rs63751124, rs587779014, rs587779015, rs63749820, rs63751302, rs267607750, rs267607751, rs267607749, rs63750891, rs63749959, rs63749804, rs267607765, rs267607760, rs587779021, rs267607759, rs63750515, rs587779023, rs63751021, rs63751480, rs267607772, rs267607773, rs587779024, rs63751653, rs587779027, rs267607767, rs587779029, rs63750706, rs63750385, rs267607774, rs267607778, rs267607780, rs587779034, rs63751711, rs267607784, rs587779035, rs63750823, rs63750822, rs267607787, rs63750303, rs63749839, rs63749827, rs267607789, rs267607790, rs267607791, rs267607786, rs267607771, rs267607795, rs267607794, rs267607788, rs267607799, rs267607801, rs587779045, rs63750034, rs587779047, rs63750216, rs63751707, rs63751598, rs267607803, rs267607777, rs63750144, rs267607805, rs63750547, rs63750489, rs63750993, rs587779054, rs63751259, rs63749926, rs63750796, rs587779058, rs63750745, rs63750582, rs180177084, rs587779866, rs200389141, rs587779950, rs587780104, rs587780183, rs587778536, rs587780683, rs587781554, rs267607712, rs587777627, rs587783057, rs730881734, rs41542214, rs730881273, rs786203456, rs786201990, rs786202767, rs748005072, rs786204317, rs786204318, rs797045117, rs63750549, rs863225383, rs863225384, rs863225373, rs863225376, rs863225377, rs863225378, rs863225379, rs863225380, rs863225381, rs63750059, rs267607823, rs864622457, rs869312767, rs869312753, rs876661059, rs876658915, rs876658923, rs876660860, rs876660822, rs876660458, rs876660214, rs876658657, rs876658247, rs876659226, rs876658821, rs876660589, rs876659068, rs876659681, rs876659608, rs878853794, rs878853778, rs878853780, rs878853785, rs886039423, rs886039424, rs1057517543, rs1057517541, rs756843954, rs1057517617, rs1057517558, rs1057519256, rs1060500689, rs764085979, rs1060500707, rs1060500699, rs1060500706, rs1060500703, rs1064795341, rs1064793607, rs1064794348, rs1064795441, rs1064794373, rs1064793172, rs1064794122, rs1064795515, rs1064794331, rs63750978, rs1114167435, rs1553641362, rs63751448, rs1553648029, rs1553648058, rs587778903, rs1553653237, rs1553664353, rs267607744, rs1553647995, rs1553648047, rs1553653084, rs1553663750, rs1553664436, rs1553488015, rs1553637293, rs63750310, rs63750443, rs63751596, rs1553646681, rs550890395, rs1064796057, rs1553642079, rs1553648023, rs587782087, rs746536721, rs1553653037, rs1248251121, rs1553646602, rs1434898623, rs1553665683, rs1553648068, rs1553645331, rs1553644123, rs1553658246, rs1553651299, rs1553648149, rs1553663159, rs1302248679, rs1553664119, rs1553658009, rs1553665977, rs1416171624, rs1553663834, rs1553664617, rs1553664702, rs1553647969, rs1553648040, rs1437454428, rs1553641273, rs63751101, rs1553646764, rs1553648225, rs1554082118, rs1553648201, rs1553638868, rs1553665866, rs376736188, rs1553642707, rs1553645226, rs1553652883, rs63751435, rs1553653115, rs1553653195, rs63750300, rs1553662622, rs1553658104, rs1553648220, rs1559544064, rs63750584, rs267608083, rs1559551570, rs1559575107, rs1559553501, rs1565986506, rs1559524405, rs1559553492, rs1559554339, rs1559588540, rs1559558071, rs761329565, rs1559521039, rs1559574795, rs1567221417, rs1559578422, rs1481129490, rs1570714352, rs779783209, rs1575376830, rs1575469070, rs1575537843, rs1575620443, rs1575621506, rs587779022, rs1575414904, rs1575449093, rs1575469505, rs1575536254, rs1575537933, rs1575632112, rs1575639851, rs1575441094, rs1575449402, rs267607831, rs2081922847, rs2083403132, rs2085415927, rs2085469647, rs2043913790, rs147542208

Unknown
Disease term	Disease name	Evidence	References	Source
Congestive heart failure	Congestive heart failure		29394407	ClinVar
Heart failure	Heart failure, Left-Sided Heart Failure, Heart Failure, Right-Sided		29394407	ClinVar
Myocardial infarction	Myocardial Failure		29394407	ClinVar

Associations from Text Mining
Disease Name	Relationship Type	References
Atrial Fibrillation	Associate	21736391
Carcinoma Renal Cell	Associate	38292868
Colorectal Neoplasms	Associate	28358024
Leukemia	Associate	3011152
Neoplasms	Associate	39896807
Obesity	Associate	29115457
Squamous Cell Carcinoma of Head and Neck	Associate	39896807