KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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11014 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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KDEL endoplasmic reticulum protein retention receptor 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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KDELR2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ELP-1, ELP1, ERD2.2, OI21 |
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Chromosome
Chromosome number
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7 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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7p22.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-ter |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P33947 | ||||||||||
| Protein name | ER lumen protein-retaining receptor 2 (ERD2-like protein 1) (ELP-1) (KDEL endoplasmic reticulum protein retention receptor 2) (KDEL receptor 2) | ||||||||||
| Protein function | Membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Gol | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 212 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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